<script data-pm-proxy="intercept"></script><?xml version="1.0" encoding="UTF-8"?><rss xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:content="http://purl.org/rss/1.0/modules/content/" xmlns:atom="http://www.w3.org/2005/Atom" version="2.0" xmlns:itunes="http://www.itunes.com/dtds/podcast-1.0.dtd" xmlns:googleplay="http://www.google.com/schemas/play-podcasts/1.0"><channel><title><![CDATA[Tiny Perfusion Letter]]></title><description><![CDATA[20 recent articles from and for the perfusionist community and all those surrounding them. When we have them, you get them...]]></description><link>https://lucpuis.substack.com</link><image><url>https://substackcdn.com/image/fetch/$s_!Fa70!,w_256,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fa2c04eb5-9a38-4ec1-99c4-a1745b246f8e_640x640.png</url><title>Tiny Perfusion Letter</title><link>https://lucpuis.substack.com</link></image><generator>Substack</generator><lastBuildDate>Fri, 04 Sep 2026 19:02:08 GMT</lastBuildDate><atom:link href="/__u/lucpuis.substack.com/feed" rel="self" type="application/rss+xml"/><copyright><![CDATA[Luc Puis]]></copyright><language><![CDATA[en]]></language><webMaster><![CDATA[lucpuis@substack.com]]></webMaster><itunes:owner><itunes:email><![CDATA[lucpuis@substack.com]]></itunes:email><itunes:name><![CDATA[Luc Puis]]></itunes:name></itunes:owner><itunes:author><![CDATA[Luc Puis]]></itunes:author><googleplay:owner><![CDATA[lucpuis@substack.com]]></googleplay:owner><googleplay:email><![CDATA[lucpuis@substack.com]]></googleplay:email><googleplay:author><![CDATA[Luc Puis]]></googleplay:author><itunes:block><![CDATA[Yes]]></itunes:block><item><title><![CDATA[Tiny Perfusion Letter #830]]></title><description><![CDATA[Tiny Perfusion Letter]]></description><link>https://lucpuis.substack.com/p/tiny-perfusion-letter-830</link><guid isPermaLink="false">https://lucpuis.substack.com/p/tiny-perfusion-letter-830</guid><dc:creator><![CDATA[Luc Puis]]></dc:creator><pubDate>Tue, 01 Sep 2026 11:03:15 GMT</pubDate><enclosure url="https://substackcdn.com/image/fetch/$s_!Fa70!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fa2c04eb5-9a38-4ec1-99c4-a1745b246f8e_640x640.png" length="0" type="image/jpeg"/><content:encoded><![CDATA[<h1>Tiny Perfusion Letter</h1><p>Nothing</p><p>Sometimes, you just not want to hear anything, not read anything, not have to deal with anything</p><p>Just. Nothing.</p><p>Not a very good promotional talk to start a newsletter with &#128556;, but sometimes, it is what it is</p><p>Nevertheless,</p><p>#enjoyandshare</p><p></p><p class="button-wrapper" data-attrs="{&quot;url&quot;:&quot;https://lucpuis.substack.com/?utm_source=substack&amp;utm_medium=email&amp;utm_content=share&amp;action=share&quot;,&quot;text&quot;:&quot;Share Tiny Perfusion Letter&quot;,&quot;action&quot;:null,&quot;class&quot;:null}" data-component-name="ButtonCreateButton"><a class="button primary" href="/__u/lucpuis.substack.com/?utm_source=substack&amp;utm_medium=email&amp;utm_content=share&amp;action=share"><span>Share Tiny Perfusion Letter</span></a></p><p></p><p><strong><a href="https://journals.sagepub.com/doi/10.1177/02676591261477624">Temperature-adjusted Perfusion-metabolic Phenotyping during Cardiopulmonary Bypass: An Exploratory Study.</a></strong></p><p>Squiccimarro E, Catalano S, Colombaro C, Doronzo F, Martulli D et al.</p><p>Perfusion. 2026 Aug 14. Online ahead of print</p><p><strong><a href="https://www.annalsthoracicsurgery.org/article/S0003-4975(26)00737-X/abstract">Modified Ultrafiltration and Association with Outcomes after Neonatal Cardiac Surgery.</a></strong></p><p>Benscoter AL, Reagor JA, Timpa JG, Capone CC, Olshove V et al.</p><p>Ann Thorac Surg. 2026 Jul 28. Online ahead of print</p><p><strong><a href="https://www.scielo.br/j/ccsci/a/Zt4pQw3Vg5BVXrPpdnr3q7j/?lang=en">Perioperative Albumin versus Other Fluids to Prevent Cardiac Surgery-associated Kidney Injury: A Systematic Review and Meta-analysis of Randomized Trials.</a></strong></p><p>Darlison PR, Shehabi Y, Walker HGM, Serpa Neto A, Motorniak DC et al.</p><p>Crit Care Sci. 2026 Jul 27;38:e20260353 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://jamanetwork.com/journals/jama/fullarticle/2852324">Dapagliflozin and Acute Kidney Injury Following Cardiac Surgery: A Randomized Clinical Trial.</a></strong></p><p>Oosterom-Eijmael MJP, Hulst AH, de Oliveira NPM, Niesten ED, Wietsma NE et al.</p><p>JAMA. 2026 Jul 30:e269268. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.mdpi.com/1648-9144/62/7/1380">Endoscopic Minimally Invasive Beating-Heart Tricuspid Valve Surgery Without Jugular Vein Cannulation or Caval Snaring: Clinical Outcomes Using Novel Percutaneous Venous Cannulation.</a></strong></p><p>Salem R, Kyriakides OM, Kabbesh F, Naraghi H, Zeriouh M et al.</p><p>Medicina (Kaunas). 2026 Jul 17;62(7):1380 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.mdpi.com/2227-9067/13/7/893">Nadir Oxygen Delivery During Pediatric Cardiopulmonary Bypass and Postoperative Acute Kidney Injury: A Pilot Cohort Study.</a></strong></p><p>Kangel D, &#199;evlik B, Ali &#304;, Y&#252;cel ED, Recep E et al.</p><p>Children (Basel). 2026 Jul 3;13(7):893 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(26)00567-7/fulltext">Anticoagulation Strategies for Cardiopulmonary Bypass in Heparin-Induced Thrombocytopenia: A Brief Review and Practical Algorithm.</a></strong></p><p>Moreira V, Ligocki M, Ligocki A, Litvin R, Zakaria L, Alfirevic A.</p><p>J Cardiothorac Vasc Anesth. 2026 Jul 4. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://academic.oup.com/icvts/article/41/8/ivag207/8742043">Haematocrit During Cardiopulmonary Bypass and Risk for Acute Kidney Injury: An Observational Single-Centre Study.</a></strong></p><p>Hj&#228;rpe AK, Jeppsson A, Lannemyr L, Romlin B.</p><p>Interdiscip Cardiovasc Thorac Surg. 2026 Aug 3;41(8):ivag207 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://journals.sagepub.com/doi/10.1177/03913988261473119">Hemoperfusion Integrated Into the Cardiopulmonary Bypass Circuit Modifies Perioperative Inflammatory Trajectories.</a></strong></p><p>Zhang B, Li L, Li H, Li J, Liu H.</p><p>Int J Artif Organs. 2026 Aug 6. Online ahead of print</p><p><strong><a href="https://www.scielo.br/j/abo/a/nZJKyWkCT3FqStLCTVptKJn/?lang=en">Evaluation of Early Retinal Microvasculature Changes after Cardiopulmonary Bypass.</a></strong></p><p>&#214;zba&#351; M, Demirayak B.</p><p>Arq Bras Oftalmol. 2026 Jul 31;89(4):e20250344 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://annalsofglobalhealth.org/articles/10.5334/aogh.5185">Acute Kidney Injury After Cardiac Surgery in Low- and Middle-Income Countries.</a></strong></p><p>Ndaba E, Baloyi V.</p><p>Ann Glob Health. 2026 Jul 27;92(1):75 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.sciencedirect.com/science/article/pii/S010400142600093X">Relative Hematocrit Declines at the Time of Transfusion and Postoperative Outcomes after Coronary Artery Bypass Grafting: A Retrospective Cohort Study.</a></strong></p><p>Sadr F, Jalali A, Vakili-Basir A, Pashang M, Barkhordari K.</p><p>Braz J Anesthesiol. 2026 Aug 7:844813.Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jthjournal.org/article/S1538-7836(26)00336-3/fulltext">How to Monitor and Manage Unfractionated Heparin in Practice (Part 1)? Guidance from the SSC of the ISTH.</a></strong></p><p>Gouin-Thibault I, Frere C, Castellucci LA, Connors JM, Cuker A et al.</p><p>J Thromb Haemost. 2026 Aug;24(8):3051-3062 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC13401511/">Mean Arterial Pressure During the First 24 Hours After Cardiac Surgery and Acute Kidney Injury: An Observational Cohort Study.</a></strong></p><p>McIlroy DR, Li G, Freundlich RE, Mishra V, Wimbiscus M et al.</p><p>J Cardiothorac Vasc Anesth. 2026 Sep;40(9):2808-2819 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.sciencedirect.com/science/article/abs/pii/S1053077026004854">Combined Observations From Two Tertiary Centers Reveal Critical Limitations in a Filtration-Based Autotransfusion System During Complex Cardiac Surgery.</a></strong></p><p>van Vrouwerf E, Filius A, Vermeer H, Hoogzaad D, Ter Horst M.</p><p>J Cardiothorac Vasc Anesth. 2026 Sep;40(9):3059-3061</p><p><strong><a href="https://journals.physiology.org/doi/full/10.1152/ajpheart.00127.2026">Leukocytes in Atrial Fibrillation: Mechanisms and Therapeutics.</a></strong></p><p>Swenson GE, Fischer MA</p><p>Am J Physiol Heart Circ Physiol. 2026 Jun 25;331(2):H688-H701 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(26)00785-8/fulltext">The Relationship Between the Preoperative Gut Microbiome and SIRS after Cardiac Surgery: A Prospective Cohort Study.</a></strong></p><p>Hejndorf S, Gulay A, Zheng C, Vibeke Nielsen R, Buhl Rasmussen S et al.</p><p>J Cardiothorac Vasc Anesth. 2026 Jul 4. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(26)00798-6/abstract">Pulmonary Artery Perfusion as a Rescue Strategy for Differential Hypoxemia During Partial Cardiopulmonary Bypass in Thoracoabdominal Aortic Replacement</a></strong></p><p>Tanahira D, Okamura Y, Tomita K, Hirata N</p><p>J Cardiothorac Vasc Anesth. 2026 Aug 13. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.ovid.com/jnls/anesthesia-analgesia/abstract/10.1213/ane.0000000000008255~the-timeless-project-a-mixed-methods-analysis-of-modifiable?redirectionsource=fulltextview">The TIMELESS Project: A Mixed-Methods Analysis of Modifiable Risk Factors and Transfusion Practices in 24,000 Cardiac Surgical Cases.</a></strong></p><p>Lakda AM, Mi J, Liu X, Otrock ZK, Donaldson C et al.</p><p>Anesth Analg. 2026 Aug 17. Online ahead of print</p><p><strong><a href="https://www.jtcvsopen.org/article/S2666-2736(26)00348-7/fulltext">Use of Whole Blood in Pediatric Congenital Heart Surgery.</a></strong></p><p>Maitoza L, Bland S, Fortes PA, McGonigle A, Williams T et al.</p><p>JTCVS Open. 2026 Jun 11;32:101925 <strong>OPEN ACCESS</strong></p><p></p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://lucpuis.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">Tiny Perfusion Letter is a reader-supported publication. To receive new posts, consider becoming a free or paid subscriber.</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div><p></p>]]></content:encoded></item><item><title><![CDATA[Tiny Perfusion Letter #829]]></title><description><![CDATA[Tiny Perfusion Letter]]></description><link>https://lucpuis.substack.com/p/tiny-perfusion-letter-829</link><guid isPermaLink="false">https://lucpuis.substack.com/p/tiny-perfusion-letter-829</guid><dc:creator><![CDATA[Luc Puis]]></dc:creator><pubDate>Tue, 18 Aug 2026 12:04:58 GMT</pubDate><enclosure url="https://substackcdn.com/image/fetch/$s_!Fa70!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fa2c04eb5-9a38-4ec1-99c4-a1745b246f8e_640x640.png" length="0" type="image/jpeg"/><content:encoded><![CDATA[<h1>Tiny Perfusion Letter</h1><p>#1</p><p>Sometimes, titles of articles hit a personal note; Prof. Ken Taylor was extremely involved in the training and education of perfusionists and was present when this humble nurse (wannabe perfusionist) took their practical exam for the European Board of Cardiovascular Perfusion. Next to the Y2K bug, we were heavily hit by the OPCAB-plague around that time, and there was no pump run on the day of the exam, but somehow (sometimes, the truth needs a shroud of mystery), we went from Wannabe to Havetobe</p><p>Wild times, we guess&#8230; &#129335;</p><p>#2</p><p>Sometimes, the title of a scientific case report reads like the headlines of a newspaper&#8230;</p><p>The newspaper was a device that was used to distribute the news from the day before - a paper version of yesterday&#8217;s TikTok</p><p>Wild times, again&#8230; &#129335;</p><p>#3 Sometimes, a survey&#8230; It&#8217;s been a while, you can do it: <strong><a href="https://lime.aphp.fr/index.php/156476">intended for anaesthesiologists and perfusionists who are currently involved in the management of paediatric cardiopulmonary bypass</a></strong></p><p>#enjoyandshare</p><p></p><p class="button-wrapper" data-attrs="{&quot;url&quot;:&quot;https://lucpuis.substack.com/?utm_source=substack&amp;utm_medium=email&amp;utm_content=share&amp;action=share&quot;,&quot;text&quot;:&quot;Share Tiny Perfusion Letter&quot;,&quot;action&quot;:null,&quot;class&quot;:null}" data-component-name="ButtonCreateButton"><a class="button primary" href="/__u/lucpuis.substack.com/?utm_source=substack&amp;utm_medium=email&amp;utm_content=share&amp;action=share"><span>Share Tiny Perfusion Letter</span></a></p><p></p><p><strong><a href="https://journals.sagepub.com/doi/abs/10.1177/02676591261454814">Obituary: Professor Kenneth MacDonald &#8220;Ken&#8221; Taylor MB ChB MD FRCS FRCSE FESC FETCS FSA British Heart Foundation, Professor of Cardiac Surgery, Imperial College London</a></strong></p><p>Punjabi PP.</p><p>Perfusion. 2026 Jul 28. </p><p><strong><a href="https://www.ovid.com/jnls/jfmpc/fulltext/10.4103/jfmpc.jfmpc_1578_25~a-case-report-a-man-creates-holes-in-his-own-heart">A Case Report: A Man Creates Holes in His Own Heart.</a></strong></p><p>Wu Y, Zhang X, Liu X.</p><p>J Family Med Prim Care. 2026 Apr;15(4):1847-1849 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://academic.oup.com/ejcts/article/68/5/ezag159/8676467">Quality of Life After Cardiac Surgery: The QUACS Study and Benefit Prediction Model.</a></strong></p><p>Nashef SAM, Willard J, Mills C, Chiu YD, Noyes P et al.</p><p>Eur J Cardiothorac Surg. 2026 May 11;68(5):ezag159 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.nature.com/articles/s41746-026-02853-6">Humanoid Robots in the Operating Room: A Framework for Staged Integration of Embodied AI in Surgery.</a></strong></p><p>Kernbach JM, Brat G, Topol EJ, Rajpurkar P.</p><p>NPJ Digit Med. 2026 Jul 13. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jtcvsopen.org/article/S2666-2736(26)00399-2/fulltext">From General Guidance to Surgical Reality: Adapting the Heparin-Induced Thrombocytopenia Algorithm for Cardiac Surgery.</a></strong></p><p>Engelman D, Cuker A, Chatterjee S.</p><p>JTCVS Open. 2026 Jul 30. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jtcvsopen.org/article/S2666-2736(26)00401-8/fulltext">Weekend Versus Weekday Cardiac Surgery: A Comprehensive Meta-Analysis of Over 500,000 Cases with Meta-Regression.</a></strong></p><p>Santos K, Belen Kim Kim J, F&#225;rez C, Hakkeem B, Irakoze Habiyambere G et al.</p><p>JTCVS Open. 2026 Jul 30. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jtcvsopen.org/article/S2666-2736(26)00407-9/fulltext">Weekend Effect on Operative Mortality Following Coronary Artery Bypass Grafting.</a></strong></p><p>Squiers J, Dorton C, Pickering T, Banwait JK, Hale S et al.</p><p>JTCVS Open. 2026 Jul 30. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(26)00648-8/fulltext"><span>Propofol-Supplemented Cardioplegic Solution Effect on Myocardial Protection: A Systematic Review and Bayesian Meta-Analysis of Randomized Controlled Trials.</span></a></strong></p><p>Esparza R, Mil&#225;n R, Abbas M,</p><p>JTCVA Open. Aug 06. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(26)00790-1/abstrac">Intraoperative Thromboelastography-activated Clotting Time after Weaning from Cardiopulmonary Bypass Correlates with Fibrinogen Concentration, and Its Prolongation May Predict Hypofibrinogenemia.</a></strong></p><p>Inaba M, Ohashi N, Seino Y, Baba H.</p><p>JTCVA. 2026 Aug 09. Online ahead of print</p><p><strong><a href="https://journals.sagepub.com/doi/abs/10.1177/17504589261464832">Safe Surgery Checklist: Barriers and Facilitators for Its Implementation.</a></strong></p><p>Pereira VT, Cruz SSD, Gomes-Filho IS, Imoto AM, Ronca DB et al.</p><p>J Perioper Pract. 2026 Aug 5. Online ahead of print</p><p><strong><a href="https://www.sciencedirect.com/science/article/pii/S0956566326006457">A Methylene Blue Based Electrochemical Assay to Quantify Haemoglobin in Blood for Point-of-care Anaemia Diagnosis.</a></strong></p><p>de Mariscal-Molina N, Hern&#225;ndez G, Piper A, Rossetti M, S&#225;nchez M, Merko&#231;i A.</p><p>Biosens Bioelectron. 2026 Nov 15;312:119013 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.sciencedirect.com/science/article/abs/pii/S1053077026003897">Challenging Venous Cannulation Pre-Cardiopulmonary Bypass During Aortic Surgery: An Interesting TEE Finding.</a></strong></p><p>Toor AS, Andany AV, Cory JM, Price J, Foglia J.</p><p>J Cardiothorac Vasc Anesth. 2026 Aug;40(8):2500-2504</p><p><strong><a href="https://journals.sagepub.com/doi/abs/10.1177/02676591261462274">Initial Cardioplegia Dose Indexed to Left Ventricular Mass in Mitral Valve Surgery.</a></strong></p><p>Tang S, Ren X, Wang C, Afolabi MO, Dai M et al.</p><p>Perfusion. 2026 Jul 10. Online ahead of print</p><p><strong><a href="https://journals.sagepub.com/doi/abs/10.1177/02676591261467979">Efficacy of Intraoperative Hemoadsorption in Patients Undergoing Cardiac Surgery, A Meta-analysis.</a></strong></p><p>Motawea KR, Abouainain L, Amer AE, Mohamed MS, Kandil O et al.</p><p>Perfusion. 2026 Jul 7. Online ahead of print</p><p><strong><a href="https://www.imrpress.com/journal/RCM/27/7/10.31083/RCM49903">Immunothrombotic Dysregulation in Pediatric Patients Receiving Veno-arterial ECMO After Cardiac Surgery: Insights From Platelet Activation and T Cell Immune Profiling.</a></strong></p><p>Guo J, Du Z, Xu B, Yang X, Xin M et al.</p><p>Rev Cardiovasc Med. 2026 Jul 28;27(7):49903 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.cambridge.org/core/journals/cardiology-in-the-young/article/abs/extracorporeal-membrane-oxygenation-in-congenital-cardiac-surgery-a-10year-singlecentre-experience/1B23651A0C741C4A1549060EDEAFECE4">Extracorporeal Membrane Oxygenation in Congenital Cardiac Surgery: A 10-year Single-centre Experience.</a></strong></p><p>Munshi SK, Narwaley M, Generali T, Kutty R, Lotto A et al.</p><p>Cardiol Young. 2026 Jul 31:1-8. Online ahead of print</p><p><strong><a href="https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2026.1801971/full">Impact of an Early, Graduated Mobilization Program on Recovery and Postoperative Outcomes after Cardiac Revascularization with Extracorporeal Circulation.</a></strong></p><p>Liu J, Jiang M, Zhao X, Liang Y, Liu Y, Pan R.</p><p>Front Cardiovasc Med. 2026 Jul 15;13:1801971 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.mdpi.com/1648-9144/62/7/1289">Predictors of Prolonged ICU Stay After Isolated CABG: The Role of MiECC.</a></strong></p><p>&#214;zbakkalo&#287;lu A, Rahman &#214;F, Arslangilay M, Kele&#351; E, Bozkurt &#214;T et al.</p><p>Medicina (Kaunas). 2026 Jul 3;62(7):1289 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.ectrx.org/detail/supplement/2026/24/6/2/84/0">Hypothermic Oxygenated Machine Perfusion Using a Standard Cardiopulmonary Bypass System: Clinical Outcomes and Feasibility in Extended Criteria Donor Liver Transplantation.</a></strong></p><p>Shabunin AV, Drozdov PA, Minina MG, Levina ON, Astapovich SA et al.</p><p>Exp Clin Transplant. 2026 Jul;24(Suppl 2):84-92 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://academic.oup.com/icvts/article/41/8/ivag216/8748377">Blood-Based Versus Crystalloid Cardiopulmonary Bypass Priming in Left Ventricular Assist Device Surgery: Impact on End-Organ Function and Survival.</a></strong></p><p>Bonni S, Zayat R, Ramnath NWM, Hatam N, Tewarie L et al.</p><p>Interdiscip Cardiovasc Thorac Surg. 2026 Aug 3;41(8):ivag216 <strong>OPEN ACCESS</strong></p><p></p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://lucpuis.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">Tiny Perfusion Letter is a reader-supported publication. To receive new posts, consider becoming a free or paid subscriber</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div><p></p>]]></content:encoded></item><item><title><![CDATA[Tiny Perfusion Letter #828]]></title><description><![CDATA[Tiny Perfusion Letter]]></description><link>https://lucpuis.substack.com/p/tiny-perfusion-letter-828</link><guid isPermaLink="false">https://lucpuis.substack.com/p/tiny-perfusion-letter-828</guid><dc:creator><![CDATA[Luc Puis]]></dc:creator><pubDate>Tue, 11 Aug 2026 12:01:24 GMT</pubDate><enclosure url="https://substackcdn.com/image/fetch/$s_!Fa70!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fa2c04eb5-9a38-4ec1-99c4-a1745b246f8e_640x640.png" length="0" type="image/jpeg"/><content:encoded><![CDATA[<h1>Tiny Perfusion Letter</h1><p>In about one month, it will be <strong><a href="https://www.who.int/campaigns/world-patient-safety-day/2026">World Patient Safety Day</a></strong></p><blockquote><p>The 2026 edition of World Patient Safety Day focuses on addressing one of the major health concerns affecting billions of people and accounting for 74% of deaths worldwide, namely noncommunicable diseases (NCDs). Noncommunicable diseases are long-term conditions, such as cardiovascular diseases, cancers, diabetes and chronic respiratory diseases, that can affect people of all ages and often require ongoing care throughout life</p></blockquote><p>Can&#8217;t say we didn&#8217;t tell y&#8217;all!</p><p>#enjoyandshare</p><p></p><p class="button-wrapper" data-attrs="{&quot;url&quot;:&quot;https://lucpuis.substack.com/?utm_source=substack&utm_medium=email&utm_content=share&action=share&quot;,&quot;text&quot;:&quot;Share Tiny Perfusion Letter&quot;,&quot;action&quot;:null,&quot;class&quot;:null}" data-component-name="ButtonCreateButton"><a class="button primary" href="/__u/lucpuis.substack.com/?utm_source=substack&amp;utm_medium=email&amp;utm_content=share&amp;action=share"><span>Share Tiny Perfusion Letter</span></a></p><p></p><p><strong><a href="https://link.springer.com/article/10.1186/s13019-026-04540-9">Amino Acids for the Prevention of Acute Kidney Injury after Cardiac Surgery: A Narrative Review of Trials and Meta-analyses.</a></strong></p><p>Svedjeholm R, Holm J, Vanky F.</p><p>J Cardiothorac Surg. 2026 Jul 21;21(1):502 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://e-century.us/files/ajtr/18/6/ajtr0172530.pdf">Predictive Value of Oxygen Delivery and Regional Oxygen Saturation during Cardiopulmonary Bypass for Cardiac Surgery-associated Acute Kidney Injury in Neonates with Congenital Heart Disease.</a></strong></p><p>Li T, Chen H, Chen S, You T.</p><p>Am J Transl Res. 2026 Jun 15;18(6):5379-5388 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://journals.sagepub.com/doi/10.1177/02676591261471110">Innovative Use of Quality Indicators during Cardiopulmonary Bypass: A Goal Directed Perfusion Strategy Using Real-time Area Under the Threshold Analysis.</a></strong></p><p>van Hoeven M, Gensen C, Overdevest E, Gerritse M, Turco S, Bouwman A.</p><p>Perfusion. 2026 Jul 2. Online ahead of print</p><p><strong><a href="https://www.ovid.com/jnls/anesthesia-analgesia/abstract/10.1213/ane.0000000000008139~sonorheometry-quantra-qplus-characteristics-in-adult-cardiac?redirectionsource=fulltextview">Sonorheometry Quantra QPlus Characteristics in Adult Cardiac Surgical Patients: An Observational Cohort Study.</a></strong></p><p>Knio ZO, Marche CA, Khan J, McNeil JS, Singh KE, Mazzeffi MA.</p><p>Anesth Analg. 2026 Jul 20. Online ahead of print</p><p><strong><a href="https://journals.sagepub.com/doi/10.1177/21501351261450092">Methodological Considerations in Interpreting Inflammatory Mediator Profiles Following Pediatric Cardiopulmonary Bypass Prime Exposure.</a></strong></p><p>Thakkar R, Raina D, Maji C, Anjum V.</p><p>World J Pediatr Congenit Heart Surg. 2026 Jul 18. Online ahead of print</p><p><strong><a href="https://journals.sagepub.com/doi/10.1177/03913988261462526">Design and In Vitro Evaluation of a Parallel Gas-exchange Chambers Oxygenator with Reduced Hemolysis and Pressure Drop.</a></strong></p><p>Liu Y, Yu J, Zhu Y, Guo H, Lu Z, Yang M.</p><p>Int J Artif Organs. 2026 Jul 2. Online ahead of print</p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(26)00560-4/fulltext">Incidence and Temporal Changes of Transfusion and Coagulation Management in Cardiac Surgery: Insights From the Netherlands Heart Registration.</a></strong></p><p>Schaap CM, Schenk J, Eberl S, M&#252;ller MCA, Vlaar APJ et al.</p><p>J Cardiothorac Vasc Anesth. 2026 Jul 4. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://associationofanaesthetists-publications.onlinelibrary.wiley.com/doi/ftr/10.1111/anae.70306">Postoperative Anaemia and Long-term Survival Following Cardiac Surgery: A Multicentre, Retrospective, Observational Study.</a></strong></p><p>Boyko Y, Lindhardt RB, Chen M, Bartozko J, Andersen CL et al.</p><p>Anaesthesia. 2026 Jul 21. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1007/s12055-026-02193-w">Coronary Artery Bypass Grafting In a Patient with Factor XIII Deficiency: Case Report and Review of Perioperative Management.</a></strong></p><p>Kanthimathinathan S, Machiraju PK, Sridhar LF, Pandurangan P, Namala SP, Singanamala S.</p><p>Indian J Thorac Cardiovasc Surg. 2026 Aug;42(8):1016-1020 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.nature.com/articles/s44161-026-00831-5">An Integrated Cell Atlas of 2.4 Million Cardiac Cells Across 209 Individuals in Health and Disease.</a></strong></p><p>Datar Y, Chaffin M, Simonson B, Mandia A, Ellinor PT.</p><p>Nat Cardiovasc Res. 2026 Jul;5(7):624-63 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.cell.com/cell/fulltext/S0092-8674(26)00760-9">The Intrinsic Cardiac Nervous System is Essential for Cardiac Function and Survival.</a></strong></p><p>Xu QJ, Applegate MC, Hsu IY, Kogan RP, Hafez OA et al.</p><p>Cell. 2026 Jul 22. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jtcvsopen.org/article/S2666-2736(26)00397-9/fulltext">Retrograde Lower Body Perfusion Is Associated with Reduced Acute Kidney Injury in Stage II Palliation for Hypoplastic Left Heart Syndrome</a></strong></p><p>Zajonz T, Edinger F, Sturm N, Beran R, Bosch C et al.</p><p>JTCVS Open. 2026 Jul 25. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(26)00645-2/fulltext">Malignant Hyperthermia (MH) During Cardiothoracic Surgery: An Analysis of the National Inpatient Sample (NIS).</a></strong></p><p>Shekhar AC, Wethington M, Wethington A, Pinzon N, Raveendran G et al.</p><p>J Cardiothorac Vasc Anesth. 2026 Jul 31. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://journals.physiology.org/doi/full/10.1152/ajplung.00101.2026">Piecing Together the Alveolar-capillary Unit: Arterial-venous Capillary Polarization.</a></strong></p><p>Majka SM, Niethamer TK, Caporarello N, Thorndyke HF, Clair G et al.</p><p>Am J Physiol Lung Cell Mol Physiol. 2026 Jul 1;331(1):L57-L69 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://journals.physiology.org/doi/full/10.1152/ajplung.00141.2026">V&#775;CO<sub>2</sub>: The Essential Underpinning to Homeostatic Control of Breathing.</a></strong></p><p>Dempsey JA, McCrimmon DR.</p><p>Am J Physiol Lung Cell Mol Physiol. 2026 Jul 1;331(1):L34-L47 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s41077-026-00448-5">AI Integration in Healthcare Simulation Debriefing: Support or Substitute?</a></strong></p><p>Stocks L, Place M, Brazil V, Kainth R, Lowe B et al.</p><p>Adv Simul (Lond). 2026 Jun 10. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.sciencedirect.com/science/article/pii/S174270612600437X">Enhanced Antithrombogenic Performance of Microfluidic Oxygenators Through Dual Bioactive Surface Modification for An Artificial Placenta System.</a></strong></p><p>Li S, Sojan A, Wang S, Atkinson HM, Fusch G et al.</p><p>Acta Biomater. 2026 Aug;220:44-55 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s13019-026-04549-0">Impact of Red Blood Cell Transfusion on Clinical Outcomes after Cardiovascular Surgery: A Reconstructed Time-to-event Meta-analysis.</a></strong></p><p>Obi OS, Kumar V, Rajith G, Avila MS, Mohammed OF et al.</p><p>J Cardiothorac Surg. 2026 Jul 29. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s13019-026-04500-3">Navigating Anticoagulation in Heart Transplantation with Thrombin&#8211;Antithrombin Complex: When Conventional Monitoring Fails.</a></strong></p><p>Liu C, Ling L, Huang, X, Yu Z, Wang S,Zhou J.</p><p>J Cardiothorac Surg 2026 Jul 28. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s13019-026-04607-7">Randomized Pilot Trial of Intraoperative Hemoadsorption in Clopidogrel Treated Patients Undergoing Urgent Coronary Artery Bypass Grafting.</a></strong></p><p>Jahangirifar A, Mirtajani SB, Al-Aamri I, Al-Lawati K, Hosseinzadeh M et al. </p><p>J Cardiothorac Surg 2026 Jul 28. Online ahead of print <strong>OPEN ACCESS</strong></p><p></p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://lucpuis.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">Tiny Perfusion Letter is a reader-supported publication. To receive new posts, consider becoming a free or paid subscriber.</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div><p></p>]]></content:encoded></item><item><title><![CDATA[Tiny Perfusion Letter #827]]></title><description><![CDATA[Tiny Perfusion Letter]]></description><link>https://lucpuis.substack.com/p/tiny-perfusion-letter-827</link><guid isPermaLink="false">https://lucpuis.substack.com/p/tiny-perfusion-letter-827</guid><dc:creator><![CDATA[Luc Puis]]></dc:creator><pubDate>Tue, 04 Aug 2026 12:01:29 GMT</pubDate><enclosure url="https://substackcdn.com/image/fetch/$s_!Fa70!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fa2c04eb5-9a38-4ec1-99c4-a1745b246f8e_640x640.png" length="0" type="image/jpeg"/><content:encoded><![CDATA[<h1>Tiny Perfusion Letter</h1><p>We can safely assume that cardiac surgery still is the discipline with the highest relative consumption of blood products</p><p>Many perfusionists are also responsible for cellsavers, acute normovolemic hemodilution, and hopefully member of a Patient Blood Management (PBM) Committee in the center where they work</p><p>Therefore, we&#8217;re focusing on some of the many resources available online on PBM, next to the more traditional literature sources</p><p>There is a TON of information out there on PBM, with many societies and possibilities for networking, listening to podcasts, attending conferences and email alerts</p><p>In random order:</p><ul><li><p><strong><a href="https://www.transfusionevidencelibrary.com/">Transfusion Evidence Library</a></strong> is an information resource&#8230; </p></li><li><p><strong><a href="https://transfusionnews.com/">Transfusion News</a></strong> brings you the latest news in blood banking&#8230;</p></li><li><p><strong><a href="https://www.aabb.org/home">AABB</a></strong>  (Association for the Advancement of Blood &amp; Biotherapies) is an international, not-for-profit association representing individuals and institutions involved&#8230; (they publish</p></li><li><p><strong><a href="https://onlinelibrary.wiley.com/journal/15372995">Transfusion</a></strong> </p></li><li><p><strong><a href="https://ifpbm.org/">IFPBM</a></strong> (International Foundation for Patient Blood Management) is a multi-faceted organization&#8230;</p></li><li><p><strong><a href="https://sabm.org/">SABM</a></strong> (Society for the Advancement of Patient Blood Management) is an international, evidence-based educational resource network of excellence&#8230;</p></li><li><p><strong><a href="https://nataonline.com/">NATA</a></strong> (Network for the Advancement of Patient Blood Management, Haemostasis and Thrombosis - formerly known as Network for the Advancement of Transfusion Alternatives) is a global independent medical association&#8230;</p></li><li><p>Then there&#8217;s this guy &#8212; <strong><a href="https://www.bbguy.org/">BloodBankGuy</a></strong></p></li></ul><p>Don&#8217;t say you didn&#8217;t know&#8230; &#128578;&#8205;&#8596;&#65039; &#129656;&#129656;&#129656;</p><p>#enjoyandshare</p><p></p><p class="button-wrapper" data-attrs="{&quot;url&quot;:&quot;https://lucpuis.substack.com/?utm_source=substack&amp;utm_medium=email&amp;utm_content=share&amp;action=share&quot;,&quot;text&quot;:&quot;Share Tiny Perfusion Letter&quot;,&quot;action&quot;:null,&quot;class&quot;:null}" data-component-name="ButtonCreateButton"><a class="button primary" href="/__u/lucpuis.substack.com/?utm_source=substack&amp;utm_medium=email&amp;utm_content=share&amp;action=share"><span>Share Tiny Perfusion Letter</span></a></p><p></p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(26)00563-X/fulltext">Central and Mixed Venous Oxygen Saturation in Cardiac Surgery: A Systematic Review and Meta-Analysis</a></strong></p><p>Guarnieri M, Baggio L, Amendolagine L, Mincolelli A, De Cari D et al.</p><p>J Cardiothorac Vasc Anesth. 2026 Jul 5. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://ject.edpsciences.org/articles/ject/full_html/2026/02/ject250090/ject250090.html">Understanding Pressure Excursions in Extracorporeal Technologies: The Role of Shear Stress and Hematologic Predisposition.</a></strong></p><p>El Dsouki Y, Cirullo C, D&#8217;Alessandro A, Condello I.</p><p>J Extra Corpor Technol. 2026 Jun;58(2):205-207 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://ject.edpsciences.org/articles/ject/full_html/2026/02/ject250087/ject250087.html">Estimation of Hemoglobin Concentration at the Initiation of Cardiopulmonary Bypass Using Support Vector Regression.</a></strong></p><p>Hirano H, Takahashi S, Kamei T, Hibiya M.</p><p>J Extra Corpor Technol. 2026 Jun;58(2):128-138 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://ject.edpsciences.org/articles/ject/full_html/2026/02/ject250068/ject250068.html">Comparison of Clinical Outcomes between Pulsatile and Non-pulsatile Perfusion during Cardiopulmonary Bypass: A Prospective Randomized Study.</a></strong></p><p>Sharma A, Luitel P, Khakural P, Sapkota R.</p><p>J Extra Corpor Technol. 2026 Jun;58(2):117-123 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://ject.edpsciences.org/articles/ject/full_html/2026/02/ject250080/ject250080.html">Simulation Use in Perfusion Education: A 2025 Survey of United States Programs.</a></strong></p><p>Bienstock J, Searles B, Darling E.</p><p>J Extra Corpor Technol. 2026 Jun;58(2):102-109 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://journals.sagepub.com/doi/abs/10.1177/21501351261450526">Integration of the Korean and World Databases for Pediatric and Congenital Heart Surgery: A Model for Global Registry Collaboration.</a></strong></p><p>St Louis JD, Bateson BP, Broser T, Jeong CL, Rudraraju R et al.</p><p>World J Pediatr Congenit Heart Surg. 2026 Jun 30. Online ahead of print</p><p><strong><a href="https://www.sciencedirect.com/science/article/pii/S095656632600549X">Field-effect Transistors for Electrophysiological Monitoring of Cardiac and Nervous System.</a></strong></p><p>Zhang T, Li H, Li N, Zhao X, Meng Q et al.</p><p><span>Biosens Bioelectron. 2026 Nov 1;311:118917</span></p><p><strong><a href="https://www.sciencedirect.com/science/article/abs/pii/S0956566326006342">A Heart-on-a-chip Simultaneously Monitoring Contractility and Troponin Secretion Under Dynamic Mechanical Stimulation</a></strong></p><p>Zhang W, Wang Y, Yu J, Wang K, Xing L et al.</p><p>Biosens Bioelectron. 2026 Nov 1;311:119002</p><p><strong><a href="https://www.jtcvsopen.org/article/S2666-2736(26)00371-2/fulltext">Head&#8211;core Temperature Discordance during Hypothermic Circulatory Arrest in Acute Type A Aortic Dissection</a></strong></p><p>Wakisaka H, Takashima N, Suzuki T.</p><p><span>JCTVS Open. 2026 Jul 1. Online ahead of print </span><strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(26)00577-X/abstract">Cerebral Autoregulation During Antegrade Cerebral Perfusion in Neonates Undergoing Congenital Cardiac Surgery</a></strong></p><p>Fang ZA, Marino BS, Brady KM.</p><p>J Cardiothorac Vasc Anesth. 2026 Jul 10. Online ahead of print</p><p><strong><a href="https://link.springer.com/article/10.1007/s00431-026-07231-8">Fluid Balance during PICU Stay in Children after Cardiac Surgery with Cardiopulmonary Bypass.</a></strong></p><p>Luppes VAC, Pamir Z, Blom NA, Hazekamp MG, Roeleveld PP et al.</p><p>Eur J Pediatr. 2026 Jul 10;185(8):566 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.nature.com/articles/s41598-026-60608-5">Feasibility and Safety of a Novel Activated Leukocyte Adsorption Device during Cardiopulmonary Bypass: A First-in-human Pilot Study.</a></strong></p><p>Yan W, Zhang W, Mao X, Yuan H, Xiong Y.</p><p>Sci Rep. 2026 Jul 7. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://academic.oup.com/icvts/article/41/7/ivag186/8726271">Sex-Related Long-Term Outcomes in On-Pump Coronary Artery Bypass Grafting-A Propensity Score-Matched Analysis.</a></strong></p><p>Knochenhauer T, Sobik F, Pausch J, Detlef I, Brickwedel J et al.</p><p>Interdiscip Cardiovasc Thorac Surg. 2026 Jul 1;41(7):ivag186 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.bjaopen.org/article/S2772-6096(26)00051-1/fulltext">The Association of Estimated Citrate Load with Frozen Plasma versus Four-factor Prothrombin Complex Concentrate for Coagulopathy after Cardiac Surgery: A Post Hoc Exploratory Analysis of the FARES-II Randomised Controlled Trial.</a></strong></p><p>Tanaka KA, Butt AL, Stewart KE, Pezeshki G, Werner S et al.</p><p>BJA Open. 2026 Jun 29;19:100577 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(26)00494-5/abstract">Effect of the Duration of Cardiopulmonary Bypass on Oxygenation Predicted by Measuring Thoracic Fluid Content Using Electrical Cardiometry in Infants Undergoing Closure of Ventricular Septal Defect:A Prospective Observational Study.</a></strong></p><p>Laguduva AH, Gharde P, Chauhan S, Ramakrishnan L, Prakash M et al.</p><p>J Cardiothorac Vasc Anesth. 2026 Jun 11. Online ahead of print</p><p><strong><a href="https://www.cureus.com/articles/499618-the-mambo-framework-and-the-future-of-modern-perfusion-artificial-intelligence-cognitive-ergonomics-and-sustainable-workflow-integration#!/">The MAMBO Framework and the Future of Modern Perfusion: Artificial Intelligence, Cognitive Ergonomics, and Sustainable Workflow Integration.</a></strong></p><p>Condello I, El Dsouki Y.</p><p>Cureus. 2026 Jun 8;18(6):e110501 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s12872-026-06168-y">Silent Cerebral Infarction after Proximal Thoracic Aortic Surgery under Deep Hypothermic Circulatory Arrest: An Exploratory Prospective DW-MRI Study.</a></strong></p><p>Bozkurt B, Ak&#305;nc&#305; O, Ku&#351; MK, &#214;ren C, Y&#305;ld&#305;z Z et al.</p><p>BMC Cardiovasc Disord. 2026 Jul 6. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s41077-026-00462-7">Conceptions of Human Factors in Simulation-based Education: A Phenomenographic Study.</a></strong></p><p>Kitt A, Kainth R.</p><p>Adv Simul (Lond). 2026 Jul 8.Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s13019-026-04578-9">Partial Carina Resection, Reconstruction, and Left Pneumonectomy under Median Sternotomy Combined with Cardiopulmonary Bypass: A Case Report.</a></strong></p><p>Guo Y, Wang J, Zhang G, Tong T, Jin C.</p><p>J Cardiothorac Surg. 2026 Jul 19.Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s13019-026-04114-9">Partial Cardiopulmonary Bypass in Thoracoabdominal Aorta Repair: A Safe Alternative in a Low-volume Center.</a></strong></p><p>Nunez-Ordonez N, Senosiain J, Sarmiento JA, Villa CA, Obando C et al.</p><p>J Cardiothorac Surg. 2026 Jul 19. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s13019-026-04541-8">Predictive Value of Preoperative Hematologic Inflammation Indices (NLR, PLR, SII) and Clinical Risk Factors in Predicting Postoperative Pulmonary Complications after Elective Isolated On-pump Coronary Artery Bypass Grafting: A Retrospective Cohort Study of 1034 Patients.</a></strong></p><p>Vezir &#214;, Tekin EE.</p><p>J Cardiothorac Surg. 2026 Jul 18. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s13019-026-04513-y">Efficacy and Safety of Prothrombin Complex Concentrate versus Fresh Frozen Plasma in Adult Patients Undergoing Cardiac Surgery: A Systematic Review and Meta-analysis.</a></strong></p><p>Hameed MS, Razzaq A, Zia A, Iftihar A, Zaeem M et al.</p><p>J Cardiothorac Surg. 2026 Jul 17. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s13019-026-04480-4">Mortality-related Predictors in Patients Receiving Extracorporeal Membrane Oxygenation after Coronary Artery Bypass Grafting: A Retrospective Study. </a></strong></p><p>Zhang C, Feng C, Zhang P, Kan Y, Liu A et al. </p><p>J Cardiothorac Surg. 2026 Jul 5. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s13019-026-04403-3">Risk Factors and Outcomes of Early Postoperative Complications Following Congenital Heart Surgery: A Retrospective Study at a Tertiary Care Hospital in Nairobi, Kenya.</a></strong></p><p>Adan NI, Orwa J, Ahmed I, Awori M, Del Rossi S. </p><p>J Cardiothorac Surg. 2026 Jul 25. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s13019-026-04532-9">Imbalance between Oxygen Delivery and Consumption during Cooling and Rewarming Phases of Cardiopulmonary Bypass and Association with Hyperlactatemia in Total Aortic Arch Replacement: A Prospective Observational Study.</a></strong></p><p>Peng L, Wei W, Du L, Xiong J.</p><p>J Cardiothorac Surg. 2026 Jul 20. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.ctsnet.org/article-video/direct-axillary-artery-cannulation-with-the-open-seldinger-technique/">Direct Axillary Artery Cannulation With the Open Seldinger Technique.</a></strong></p><p>Karaa&#287;a&#231; A, G&#246;k&#231;e I, Arslanhan G, Bastopcu M, Ozcan ZS et al.</p><p>CTSNET. 2026 Jul 9. <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jtcvsopen.org/article/S2666-2736(26)00377-3/fulltext">Pericardial Fluid Cardiac Troponin I Predicts Postoperative Atrial Fibrillation after Coronary Artery Bypass Grafting.</a></strong></p><p>Shu Y, Gao C, Ren X, Deng X, Luo L. et al.</p><p>JCTVS Open. 2026 Jul 6. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.heartandlung.org/article/S0147-9563(26)00177-9/abstract">Determinants of Postoperative Recovery after Cardiac Surgery in Older Adults: A Multidimensional Cross-sectional Study.</a></strong></p><p>Basli A, I&#351;&#305;kl&#305; A, H&#252;seyin S.</p><p>Heart Lung. 2026 Jul 25;80:102893. Online ahead of print</p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(26)00574-4/abstract">Coagulation-Friendly Environment in Cardiac Surgery. A Narrative Review.</a></strong></p><p>Y&#233;venes F, Bolliger D, Di Dedda U, Ahmed A, Koller T et al.</p><p>J Cardiothorac Vasc Anesth. 2026 Jul 12. Online ahead of print</p><p><strong><a href="https://www.jhltopen.org/article/S2950-1334(26)00151-5/fulltext">Distinct Goal-directed Perfusion Signatures in Donation after Brain Death versus Circulatory Death Heart Transplantation.</a></strong></p><p>Wang C, Ahmad A, Petrovic M, </p><p>JHLT Open. 2026 Nov:14;100630. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jtcvs.org/article/S0022-5223(26)01151-7/abstract">Proteomic, Transcriptomic, and Metabolic Mediators of Post-Cardiopulmonary Bypass Vasoplegia Syndrome.</a></strong></p><p>Galloway A, Magro C, Goparaju C, Phillips K, Tokoro K et al.</p><p>J Thorac Cardiovasc Surg. 2026 Jul 15. Online ahead of print </p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(26)00393-9/fulltext">Evaluation of Activated Clotting Time Response to Unfractionated Heparin in Vascular Surgery: An Observational Study.</a></strong></p><p>Garberi R, Milan M, Palermo R, Segramora VM, Casati M et al.</p><p>J Cardiothorac Vasc Anesth. 2026 Aug;40(8):2466-2473 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(26)00587-2/fulltext">Preoperative Glycocalyx Status and Postoperative Organ Failure after Cardiac Surgery in the GLYPOCS Observational Cohort Study.</a></strong></p><p>Molkhou C, Demailly Z, Ait-Ali C, Kouadri G, Clavier T et al.</p><p>J Cardiothorac Vasc Anesth. 2026 Jul 21. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(26)00637-3/fulltext">Blood Glucose Variability and Postoperative Organ Function in Coronary Artery Bypass Grafting: A Prospective Cohort Study of Microcirculatory Perfusion and Oxygenation.</a></strong></p><p>Mansjoer A, Alwi I, Yunir E, Aditianingsih D, Harimurti K et al.</p><p>J Cardiothorac Vasc Anesth. 2026 Jul 29. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jtcvs.org/article/S0022-5223(26)00772-5/abstract">Pulses That Predict: Postoperative Perfusion Index and Outcomes in High-risk Pediatric Cardiac Surgery.</a></strong></p><p>Cater DT, Friedman ML, Murphy LD, Puranik P, Turrentine MW, Lutfi R.</p><p>J Thorac Cardiovasc Surg. 2026 Aug;172(2):271-279</p><p><strong><a href="https://journals.sagepub.com/doi/full/10.1177/15569845261457046">Artificial Intelligence for Predicting Perioperative Outcomes in Cardiac Surgery: A Systematic Review.</a></strong></p><p>Ha J, Vohra HA.</p><p>Innovations (Phila). 2026 Jul 13. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.ovid.com/jnls/simulationinhealthcare/abstract/10.1097/sih.0000000000000919~promoting-psychological-safety-for-all-participants-during-a?cid=eTOC+Issues.2026-simulationinhealthcare-01266021-202608000-00000&amp;rid=E_0000000006294323&amp;TargetID=&amp;EjpToken=zg06cMIOzQAuXdg-e6YM5xaQFi5tPd7syuPc4qVetNdFjYI835gQxS9bQJzi1g0SEclMb8ZsTbOpdP-WOQ&amp;mkt_tok=NjgxLUZIRS00MjkAAAGjU0hnLRCshTkQI-RVBMu6-doETxaBCBQG0cEwKlmbDMeTA2YhkAW6ZWMn4MbnInpRIZmqdJM-BJwLOg0mnU37bvzvnA_xpYUva53INkDPVLlrpZOJdzgv&amp;redirectionsource=fulltextview">Promoting Psychological Safety for All Participants During a High-Intensity Interprofessional Simulation Event.</a></strong></p><p>Greene EA, Williams JK, Nicholson RM, Kumer KD, Best NI et al.</p><p>Simul Healthc. 2026 Aug 1;21(4):247-251</p><p><strong><a href="https://onlinelibrary.wiley.com/doi/10.1111/ijlh.70195">Laboratory Monitoring Unfractionated Heparin Treatments: Unanswered Issues.</a></strong></p><p>Toulon P.</p><p>Int J Lab Hematol. 2026 Jul 14. Online ahead of print</p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(26)00508-2/abstract">Heparin Dose-Response Curve for Heparin Dose Determination During Cardiopulmonary Bypass for Pediatric Cardiac Surgery: A Prospective Randomized Controlled Study.</a></strong></p><p>Gokhale P, Hasija S, Choudhury A, B SG, Yadav M, Chauhan S.</p><p>J Cardiothorac Vasc Anesth. 2026 Jun 27. Online ahead of print</p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(26)00500-8/fulltext">Concordance of Activated Partial Thromboplastin Time and Anti&#8210;Factor Xa Levels in Monitoring Heparin Therapy Among Cardiac Surgery Patients in Pre- and Postoperative Settings.</a></strong></p><p>O&#8217;Connor K, Cassiere HA, Islam S, Chang TY, Sherman N, Yu PJ.</p><p>J Cardiothorac Vasc Anesth. 2026 Jun 23. Online ahead of print <strong>OPEN ACCESS</strong></p><p></p><p><strong>40</strong></p><p></p><p><strong><a href="https://www.jstage.jst.go.jp/article/scrj/12/1/12_cr.26-0380/_article">Adequate Venous Drainage Does Not Exclude Cannula Malposition: Right Ventricular Perforation during Minimally Invasive Aortic Valve Replacement.</a></strong></p><p>Oue K, Kinoshita M, Okuda S, Kondo N.</p><p>Surg Case Rep. 2026;12(1):26-0380 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.ovid.com/jnls/aoca/fulltext/10.4103/aca.aca_290_25~harbinger-of-difficult-weaning-from-cardiopulmonary-bypass">Harbinger of Difficult Weaning from Cardiopulmonary Bypass in Aortic Valve Replacement Surgery: A Case Report.</a></strong></p><p>Deepak A, Kuppuswamy B, Davis K, Andugala SS.</p><p>Ann Card Anaesth. 2026 Jul 1;29(3):430-433 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.ovid.com/jnls/aoca/fulltext/10.4103/aca.aca_21_26~relationship-between-entropy-guided-sevoflurane">Relationship Between Entropy-Guided Sevoflurane Administration and End Oxygenator Sevoflurane Concentration in Adult Patients Undergoing Cardiopulmonary Bypass Surgery.</a></strong></p><p>Kumar V, Kumar A, Gourav KP, Devarakonda B.</p><p>Ann Card Anaesth. 2026 Jul 1;29(3):378-385 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.ovid.com/jnls/md-journal/fulltext/10.1097/md.0000000000049765~combining-biomarkers-with-clinical-risk-factors-to-predict">Combining Biomarkers with Clinical Risk Factors to Predict Acute Kidney Injury after Cardiopulmonary Bypass Surgery: An Observational Cohort Study.</a></strong></p><p>Xu X, Liang Y, Shi S, Si H, Cheng A et al.</p><p>Medicine (Baltimore). 2026 Jul 10;105(28):e49765 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(26)00495-7/fulltext">Superiority of Fibrinogen Concentrate Versus Cryoprecipitate for Treatment of Bleeding in Cardiac Surgery Patients: A Secondary Analysis of the FIBRES Randomized Clinical Trial Stratified by Surgical Risk.</a></strong></p><p>Bartoszko J, Karkouti K, Callum JL.</p><p>J Cardiothorac Vasc Anesth. 2026 Jun 17. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.ovid.com/jnls/anesthesia-analgesia/abstract/10.1213/ane.0000000000008221~clinical-effectiveness-of-acute-normovolemic-hemodilution-in?redirectionsource=fulltextview">Clinical Effectiveness of Acute Normovolemic Hemodilution in Cardiac Surgery: A Systematic Review and Meta-analysis.</a></strong></p><p>Elfiki M, Elfeky A, Ali MS, Ibrahim A, Zayed M et al.</p><p>Anesth Analg. 2026 Jul 13. Online ahead of print</p><p><strong><a href="https://link.springer.com/article/10.1007/s12265-026-10791-7">Is Preoperative Serum Bicarbonate an Undervalued Risk Factor in Cardiac Surgery?</a></strong></p><p>Chorney W, Hinchion J.</p><p>J Cardiovasc Transl Res. 2026 Jul 13;19(1):89 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1007/s00246-026-04399-6">Postoperative Hematocrit and Lactate Trajectory After Neonatal Cardiopulmonary Bypass: A Retrospective Cohort Study.</a></strong></p><p>Rehman MU, Whitehorn M, Torgerson D, Fineman JR, Steurer MA.</p><p>Pediatr Cardiol. 2026 Jul 24. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s13019-026-04538-3">Association Between Preoperative Hydration and Cardiac Surgery-associated Acute Kidney Injury: A Prospective Observational Study.</a></strong></p><p>Mohsen G, Wallqvist J, Lee ZY, Buckenmayer A, Oppenkowski JV et al.</p><p>J Cardiothorac Surg. 2026 Jul 23;21(1):505 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.bjanaesthesia.org/article/S0007-0912(26)00413-7/abstract">Sevoflurane Diffusion Across Four Paediatric Cardiopulmonary Bypass Oxygenators: A Laboratory Investigation.</a></strong></p><p>Dubernet M, Bonnet V, Vanden Dorpe T, Hennart B, Wiart JF, Moussa MD.</p><p>Br J Anaesth. 2026 Jul 2. Online ahead of print</p><p></p><p>&#127881;&#127881;&#127881; You made it all the way down on the list!! Congratulations!</p><p></p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://lucpuis.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">Tiny Perfusion Letter is a reader-supported publication. To receive new posts, consider becoming a free or paid subscriber.</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div><p></p>]]></content:encoded></item><item><title><![CDATA[Tiny Perfusion Letter #826]]></title><description><![CDATA[Tiny Perfusion Letter]]></description><link>https://lucpuis.substack.com/p/tiny-perfusion-letter-826</link><guid isPermaLink="false">https://lucpuis.substack.com/p/tiny-perfusion-letter-826</guid><dc:creator><![CDATA[Luc Puis]]></dc:creator><pubDate>Tue, 28 Jul 2026 12:03:17 GMT</pubDate><enclosure url="https://substackcdn.com/image/fetch/$s_!Fa70!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fa2c04eb5-9a38-4ec1-99c4-a1745b246f8e_640x640.png" length="0" type="image/jpeg"/><content:encoded><![CDATA[<h1>Tiny Perfusion Letter</h1><p>While you are doing your daily job in the OR, animal lab, ICU, cathlab, meeting room, conference hall, or just enjoying a wonderful day off, it is sometimes necessary to think about the less obvious sides of the profession:</p><p>Legislation. Licenses. Credentialing. Bills. Acts. Scopes of Practice. &#128565;&#8205;&#128171;&#128565;&#8205;&#128171;&#128565;&#8205;&#128171;</p><p><strong>Professionalism</strong></p><p>It&#8217;s hard to keep tabs on this, but this <strong><a href="/__u/cliniciansdiary.substack.com/p/who-is-keeping-you-alive">eye-opening overview and call to action</a></strong> (see further) did all that work for you. We&#8217;re talking about you, US CCP&#8217;s. We believe it&#8217;s important you&#8217;re aware of the situation and take action in your state</p><p>We know we would, if we were a CCP (surprising shocker: we&#8217;re <strong>not</strong>)</p><p>But we have a &#129728; for the profession and we believe you have a &#129728; too, so read it and take action (ignore the fact that it states that it is not written for perfusionists&#8230;)</p><div class="embedded-post-wrap" data-attrs="{&quot;id&quot;:208401284,&quot;url&quot;:&quot;https://cliniciansdiary.substack.com/p/who-is-keeping-you-alive&quot;,&quot;publication_id&quot;:9707165,&quot;embedding_publication_id&quot;:2158756,&quot;publication_name&quot;:&quot;Tom Ferry&quot;,&quot;publication_logo_url&quot;:&quot;https://substackcdn.com/image/fetch/$s_!d2-G!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fb4cc1df7-2009-4e98-9453-111f589fa93f_1254x1254.png&quot;,&quot;title&quot;:&quot;WHO IS KEEPING YOU ALIVE?&quot;,&quot;truncated_body_text&quot;:&quot;This is not an article written for perfusionists.&quot;,&quot;date&quot;:&quot;2026-07-25T00:23:45.330Z&quot;,&quot;like_count&quot;:1,&quot;comment_count&quot;:0,&quot;bylines&quot;:[{&quot;id&quot;:488805859,&quot;name&quot;:&quot;Tom Ferry&quot;,&quot;handle&quot;:&quot;cliniciansdiary&quot;,&quot;previous_name&quot;:null,&quot;photo_url&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/b4cc1df7-2009-4e98-9453-111f589fa93f_1254x1254.png&quot;,&quot;bio&quot;:&quot;A perfusionist's account of American healthcare &#8212; the stories inside the OR, the cases that don't make the news, and the system failures hiding behind closed doors. Nothing sanitized.&quot;,&quot;profile_set_up_at&quot;:&quot;2026-06-11T13:22:16.758Z&quot;,&quot;reader_installed_at&quot;:&quot;2026-06-26T14:55:34.501Z&quot;,&quot;publicationUsers&quot;:[{&quot;id&quot;:9961979,&quot;user_id&quot;:488805859,&quot;publication_id&quot;:9707165,&quot;role&quot;:&quot;admin&quot;,&quot;public&quot;:true,&quot;is_primary&quot;:true,&quot;publication&quot;:{&quot;id&quot;:9707165,&quot;name&quot;:&quot;Tom Ferry&quot;,&quot;subdomain&quot;:&quot;cliniciansdiary&quot;,&quot;custom_domain&quot;:null,&quot;custom_domain_optional&quot;:false,&quot;hero_text&quot;:&quot;A perfusionist's account of American healthcare &#8212; the stories inside the OR, the cases that don't make the news, and the system failures hiding behind closed doors. Nothing sanitized.&quot;,&quot;logo_url&quot;:null,&quot;author_id&quot;:488805859,&quot;primary_user_id&quot;:488805859,&quot;theme_var_background_pop&quot;:&quot;#FF6719&quot;,&quot;created_at&quot;:&quot;2026-06-26T14:59:03.801Z&quot;,&quot;email_from_name&quot;:null,&quot;copyright&quot;:&quot;Tom Ferry&quot;,&quot;founding_plan_name&quot;:null,&quot;community_enabled&quot;:true,&quot;invite_only&quot;:false,&quot;payments_state&quot;:&quot;disabled&quot;,&quot;language&quot;:null,&quot;explicit&quot;:false,&quot;homepage_type&quot;:&quot;profile&quot;,&quot;is_personal_mode&quot;:false,&quot;logo_url_wide&quot;:null}}],&quot;is_guest&quot;:false,&quot;bestseller_tier&quot;:null,&quot;status&quot;:{&quot;bestsellerTier&quot;:null,&quot;subscriberTier&quot;:null,&quot;leaderboard&quot;:null,&quot;vip&quot;:false,&quot;badge&quot;:null,&quot;subscriber&quot;:null}}],&quot;utm_campaign&quot;:null,&quot;belowTheFold&quot;:false,&quot;type&quot;:&quot;newsletter&quot;,&quot;language&quot;:&quot;en&quot;,&quot;source&quot;:null}" data-component-name="EmbeddedPostToDOM"><a class="embedded-post" native="true" href="/__u/cliniciansdiary.substack.com/p/who-is-keeping-you-alive?utm_source=substack&amp;utm_campaign=post_embed&amp;utm_medium=web&amp;embedding_publication_id=2158756"><div class="embedded-post-header"><img class="embedded-post-publication-logo" src="/__u/substackcdn.com/image/fetch/$s_!d2-G!,w_56,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fb4cc1df7-2009-4e98-9453-111f589fa93f_1254x1254.png"><span class="embedded-post-publication-name">Tom Ferry</span></div><div class="embedded-post-title-wrapper"><div class="embedded-post-title">WHO IS KEEPING YOU ALIVE?</div></div><div class="embedded-post-body">This is not an article written for perfusionists&#8230;</div><div class="embedded-post-cta-wrapper"><span class="embedded-post-cta">Read more</span></div><div class="embedded-post-meta">a month ago &#183; 1 like &#183; Tom Ferry</div></a></div><p>#enjoyandshare </p><p class="button-wrapper" data-attrs="{&quot;url&quot;:&quot;https://lucpuis.substack.com/?utm_source=substack&amp;utm_medium=email&amp;utm_content=share&amp;action=share&quot;,&quot;text&quot;:&quot;Share Tiny Perfusion Letter&quot;,&quot;action&quot;:null,&quot;class&quot;:null}" data-component-name="ButtonCreateButton"><a class="button primary" href="/__u/lucpuis.substack.com/?utm_source=substack&amp;utm_medium=email&amp;utm_content=share&amp;action=share"><span>Share Tiny Perfusion Letter</span></a></p><p></p><p><strong><a href="https://www.ovid.com/jnls/transplantjournal/fulltext/10.1097/tp.0000000000005830~filtered-or-fried-rethinking-intraoperative-cell-salvage-in">Filtered or Fried? Rethinking Intraoperative Cell Salvage in Liver Transplantation.</a></strong></p><p>Biancofiore G.</p><p>Transplantation. 2026 Jul 6. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://obgyn.onlinelibrary.wiley.com/doi/10.1002/ijgo.71181">Impact of Cell Saver technology on pro-hemostatic factors transfusion in placenta accreta spectrum interventions: A 10-year retrospective single-center study.</a></strong></p><p>Levy I, Vachette M, Van Der Putten E, Chouteau M, Goffinet F et al.</p><p>Int J Gynaecol Obstet. 2026 Jul 2. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1007/s11748-026-02349-w">Blood Management with Preoperative Autologous Blood in Valve-sparing Root Replacement: Separated Autologous Red Blood Cells and Plasma and Fibrin Sealant versus Autologous Whole Blood.</a></strong></p><p>Matsumura Y, Sato T, Nagahori R, Yoshitake M, Masuzawa A et al.</p><p>Gen Thorac Cardiovasc Surg. 2026 Jun 30. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.eajm.org/index.php/pub/article/view/3297">Efficacy, Safety, and Cost-Effectiveness of Cell Salvage in Cardiac Reoperations.</a></strong></p><p>Beyazal OF, Kayalar N, Yanarta&#351; M.</p><p>Eurasian J Med. 2026 Jun 9;58(4):1-7 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s13741-026-00716-y">Perioperative Neurocognitive Disorders in Older Patients: A Narrative Review of Current Knowledge in 2026.</a></strong></p><p>Zhou X, Yang J, Tang Z, Yang S, Zhao H, Yang F.</p><p>Perioper Med (Lond). 2026 Jul 4. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s12871-026-04053-x">Sevoflurane Blood Concentrations in Patients Undergoing Mild and Moderate Hypothermic Cardiac Surgery: A Prospective Observational Study.</a></strong></p><p>Tamura T, Mori A, Imaizumi T, Yokoyama T, Nishiwaki K.</p><p>BMC Anesthesiol. 2026 Jul 4. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.sciencedirect.com/science/article/pii/S0733865126000457">Management of Shock After Cardiac Surgery.</a></strong></p><p>Deschamps J, Yao RJ, Kumar N, Zakaria L, Donaldson C, Ghadimi K.</p><p>Cardiol Clin. 2026 Aug;44(3):429-445</p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(26)00404-0/fulltext">Association Between Preoperative Iron Deficiency and Postoperative Outcomes in Children Undergoing Cardiac Surgery.</a></strong></p><p>Matisoff AJ, Teehan E, Signorile M, Schmidt M, Mooser A et al.</p><p>J Cardiothorac Vasc Anesth. 2026 May 15. Online ahead of print</p><p><strong><a href="https://journals.physiology.org/doi/full/10.1152/ajprenal.00007.2026">Nitrite Protects Against Cardiac Surgery-associated Acute Kidney Injury via Inflammation Suppression: Insights from a Rat Cardiopulmonary Bypass Model.</a></strong></p><p>Ohno S, Yoshikawa Y, Maeda M, Hirahata T, Kii N et al.</p><p>Am J Physiol Renal Physiol. 2026 Aug 1;331(2):F199-F212 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://academic.oup.com/icvts/article/41/7/ivag185/8723345">Comparison of Cannulation Strategies for Minimally Invasive Mitral Valve Surgery.</a></strong></p><p>Sromicki J, Papadopoulos N, Tr&#246;binger L, Ntinopoulos V, Hebeisen M et al.</p><p>Interdiscip Cardiovasc Thorac Surg. 2026 Jul 1;41(7):ivag185 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(26)00459-3/fulltext">An Insight Into a Potential Antithrombin-Independent Mechanism of Inadequate Heparin Response in Neonates and Infants Undergoing Pediatric Cardiac Surgery: An Exploratory Study.</a></strong></p><p>Swangwong S, Sullivan K, Malm E, Kim S, Faraoni D et al.</p><p>J Cardiothorac Vasc Anesth. 2026 May 26. Online ahead of print</p><p><strong><a href="https://onlinelibrary.wiley.com/doi/10.1155/anrp/9078621">Effects of Inspired Oxygen Concentrations During Cardiopulmonary Bypass on the Pulmonary Function of Patients Undergoing a Modified Morrow Procedure via a Small Right Axillary Incision.</a></strong></p><p>Xu L, Wang L, Yan M, Wei H, Jiang T, Wang H, Guo J, Cui Y.</p><p>Anesthesiol Res Pract. 2026 Jun 30;2026:9078621 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jtcvsopen.org/article/S2666-2736(26)00146-4/fulltext">Hypobaric Type Oxygenators during Cardiopulmonary Bypass for Cardiac Surgery to Reduce Gaseous Microemboli: A Randomized Controlled Trial.</a></strong></p><p>Gibbison B, Chotimol P, Smartt H, Reeves BC, Bamford A et al.</p><p>JTCVS Open. 2026 Mar 12;31:101723 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://academic.oup.com/icvts/article/41/7/ivag179/8721574">Postoperative C-Reactive Protein Resolution Patterns in Patients With and Without Postoperative Atrial Fibrillation After Cardiac Surgery.</a></strong></p><p>Heine M, Ulbrich F, Justice S, Saravi B, Amacher SA et al.</p><p>Interdiscip Cardiovasc Thorac Surg. 2026 Jul 1;41(7):ivag179 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1007/s10047-026-01565-8">Development of a Novel Anticoagulant and Fibrinolytic Management Monitoring Method during Extracorporeal Circulation Using Clot-fibrinolysis Waveform Analysis: The Effects of Anticoagulants on Coagulation and Fibrinolysis Functions.</a></strong></p><p>Shimizu S, Matsumoto T, Shimomura D, Soyama T.</p><p>J Artif Organs. 2026 Jun 30;29(3):40 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.sciencedirect.com/science/article/pii/S0733865126000330">Embracing Enhanced Recovery After Cardiac Surgery Program.</a></strong></p><p>Gregory AJ, Noss CD, Grant MC.</p><p>Cardiol Clin. 2026 Aug;44(3):491-506</p><p><strong><a href="https://www.sciencedirect.com/science/article/pii/S073386512600038X">Prehabilitation in Cardiac Surgery: Part 1: From Phenotype-driven Risk Stratification to Individualized Multimodal Preoperative Optimization.</a></strong></p><p>Catena D, Germinario L, Mohsen G, Hellner N, Apaydin S, Stoppe C.</p><p>Cardiol Clin. 2026 Aug;44(3):301-315</p><p><strong><a href="https://www.sciencedirect.com/science/article/pii/S0733865126000494">Prehabilitation in Cardiac Surgery: Part 2: Building a Prehab Loop and Delivering Individualized Multimodal Prehabilitation.</a></strong></p><p>Catena D, Germinario L, Mohsen G, Hellner N, Apaydin S, Stoppe C.</p><p>Cardiol Clin. 2026 Aug;44(3):317-322</p><p><strong><a href="https://journals.sagepub.com/doi/10.1177/02676591261466148">Advanced Organ Protection Strategies in Aortic Arch Surgery: A Narrative Review.</a></strong></p><p>Husen TF, Lotfalla A, Schreurs R, K&#246;rver E, Verheule S et al.</p><p>Perfusion. 2026 Jul 11. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://academic.oup.com/icvts/article/41/6/ivag145/8694815">A Comprehensive Total Body Perfusion Strategy vs Conventional Techniques in Elective Aortic Arch Surgery: A Comparative Analysis.</a></strong></p><p>Lotfalla A, Heuts S, Schreurs R, Maessen JG, Schurgers L et al.</p><p>Interdiscip Cardiovasc Thorac Surg. 2026 Jun 9;41(6):ivag145 <strong>OPEN ACCESS</strong></p><p></p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://lucpuis.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">Tiny Perfusion Letter is a reader-supported publication. To receive new posts, consider becoming a free or paid subscriber.</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div><p></p>]]></content:encoded></item><item><title><![CDATA[Tiny Perfusion Letter #825]]></title><description><![CDATA[Tiny Perfusion Letter]]></description><link>https://lucpuis.substack.com/p/tiny-perfusion-letter-825</link><guid isPermaLink="false">https://lucpuis.substack.com/p/tiny-perfusion-letter-825</guid><dc:creator><![CDATA[Luc Puis]]></dc:creator><pubDate>Tue, 21 Jul 2026 12:04:01 GMT</pubDate><enclosure url="https://substackcdn.com/image/fetch/$s_!Fa70!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fa2c04eb5-9a38-4ec1-99c4-a1745b246f8e_640x640.png" length="0" type="image/jpeg"/><content:encoded><![CDATA[<h1>Tiny Perfusion Letter</h1><p>If you ever wondered what the carbon footprint of a &#8220;cardiopulmonary bypass device&#8221; is; according to the <a href="https://www.medzerocarbon.com/">Lancet MedZero website</a>, it is 32041 gCO<sub>2</sub>e, which seems&#8230; a lot?</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!AUfl!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F271924fc-1a7a-4b0d-9482-e0aadbd7ff66_3780x2126.png" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!AUfl!, /__u/lucpuis.substack.com/w_424, /__u/lucpuis.substack.com/c_limit, /__u/lucpuis.substack.com/f_webp, /__u/lucpuis.substack.com/q_auto:good, /__u/lucpuis.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F271924fc-1a7a-4b0d-9482-e0aadbd7ff66_3780x2126.png 424w, /__u/substackcdn.com/image/fetch/$s_!AUfl!, /__u/lucpuis.substack.com/w_848, /__u/lucpuis.substack.com/c_limit, /__u/lucpuis.substack.com/f_webp, /__u/lucpuis.substack.com/q_auto:good, /__u/lucpuis.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F271924fc-1a7a-4b0d-9482-e0aadbd7ff66_3780x2126.png 848w, /__u/substackcdn.com/image/fetch/$s_!AUfl!, /__u/lucpuis.substack.com/w_1272, /__u/lucpuis.substack.com/c_limit, /__u/lucpuis.substack.com/f_webp, /__u/lucpuis.substack.com/q_auto:good, /__u/lucpuis.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F271924fc-1a7a-4b0d-9482-e0aadbd7ff66_3780x2126.png 1272w, /__u/substackcdn.com/image/fetch/$s_!AUfl!, /__u/lucpuis.substack.com/w_1456, /__u/lucpuis.substack.com/c_limit, /__u/lucpuis.substack.com/f_webp, /__u/lucpuis.substack.com/q_auto:good, /__u/lucpuis.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F271924fc-1a7a-4b0d-9482-e0aadbd7ff66_3780x2126.png 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!AUfl!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F271924fc-1a7a-4b0d-9482-e0aadbd7ff66_3780x2126.png" width="728" height="409.5" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/271924fc-1a7a-4b0d-9482-e0aadbd7ff66_3780x2126.png&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:819,&quot;width&quot;:1456,&quot;resizeWidth&quot;:728,&quot;bytes&quot;:29076,&quot;alt&quot;:null,&quot;title&quot;:null,&quot;type&quot;:&quot;image/png&quot;,&quot;href&quot;:null,&quot;belowTheFold&quot;:false,&quot;topImage&quot;:true,&quot;internalRedirect&quot;:&quot;https://lucpuis.substack.com/i/207690844?img=https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F271924fc-1a7a-4b0d-9482-e0aadbd7ff66_3780x2126.png&quot;,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="" srcset="/__u/substackcdn.com/image/fetch/$s_!AUfl!, /__u/lucpuis.substack.com/w_424, /__u/lucpuis.substack.com/c_limit, /__u/lucpuis.substack.com/f_auto, /__u/lucpuis.substack.com/q_auto:good, /__u/lucpuis.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F271924fc-1a7a-4b0d-9482-e0aadbd7ff66_3780x2126.png 424w, /__u/substackcdn.com/image/fetch/$s_!AUfl!, /__u/lucpuis.substack.com/w_848, /__u/lucpuis.substack.com/c_limit, /__u/lucpuis.substack.com/f_auto, /__u/lucpuis.substack.com/q_auto:good, /__u/lucpuis.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F271924fc-1a7a-4b0d-9482-e0aadbd7ff66_3780x2126.png 848w, /__u/substackcdn.com/image/fetch/$s_!AUfl!, /__u/lucpuis.substack.com/w_1272, /__u/lucpuis.substack.com/c_limit, /__u/lucpuis.substack.com/f_auto, /__u/lucpuis.substack.com/q_auto:good, /__u/lucpuis.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F271924fc-1a7a-4b0d-9482-e0aadbd7ff66_3780x2126.png 1272w, /__u/substackcdn.com/image/fetch/$s_!AUfl!, /__u/lucpuis.substack.com/w_1456, /__u/lucpuis.substack.com/c_limit, /__u/lucpuis.substack.com/f_auto, /__u/lucpuis.substack.com/q_auto:good, /__u/lucpuis.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F271924fc-1a7a-4b0d-9482-e0aadbd7ff66_3780x2126.png 1456w" sizes="100vw" fetchpriority="high"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption"><a href="https://edhawkins.org/about/">#ShowYourStripes</a></figcaption></figure></div><p>Lancet MedZero offers insights into different devices and disposables used in our daily practice, and with the <a href="https://wmo.int/news/media-centre/wmo-confirms-2024-warmest-year-record-about-155degc-above-pre-industrial-level">WHO declaring</a> &#8220;climate change [&#8230;] the biggest threat to global health in the 21st century&#8221;, we just might take a minute to think about how to </p><p><a href="https://www.ovid.com/jnls/annalsofsurgery/abstract/10.1097/sla.0000000000006337~improving-environmental-sustainability-of-operating-theatres">Do</a> </p><p><a href="https://medicine.nus.edu.sg/cosm/">Something</a> </p><p><a href="https://cdn.craft.cloud/019efd17-dcc2-707f-8e07-011d00d1146a/assets/issues/221_09_mja252481.pdf">About</a> </p><p>it&#8230; </p><p>(that&#8217;s 3 separate links&#8230;)</p><p>#enjoyandshare</p><p></p><p class="button-wrapper" data-attrs="{&quot;url&quot;:&quot;https://lucpuis.substack.com/?utm_source=substack&amp;utm_medium=email&amp;utm_content=share&amp;action=share&quot;,&quot;text&quot;:&quot;Share Tiny Perfusion Letter&quot;,&quot;action&quot;:null,&quot;class&quot;:null}" data-component-name="ButtonCreateButton"><a class="button primary" href="/__u/lucpuis.substack.com/?utm_source=substack&amp;utm_medium=email&amp;utm_content=share&amp;action=share"><span>Share Tiny Perfusion Letter</span></a></p><p></p><p><strong><a href="https://www.ahajournals.org/doi/10.1161/CIR.0000000000001446">Perioperative Anemia and Patient Blood Management in Cardiac Surgery: A Scientific Statement From the American Heart Association.</a></strong></p><p>Howard-Quijano K, Shore-Lesserson L, Osho A, Raphael J, Rove JY et al.</p><p>Circulation. 2026 Jun 22. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jstage.jst.go.jp/article/jject/53/2/53_87/_article/-char/en">Examining Hemodynamic Parameters Required for Goal-directed Perfusion Optimizing Oxygen Supply-demand Balance during Pediatric Cardiopulmonary Bypass.</a></strong></p><p>Misaka Y, Matsushima S, Akiyama S, Matsuhisa H, Oshima Y, Doi K. </p><p>Jpn J ExtraCorporeal Technology. 2026;53(2):87-94 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jtcvs.org/article/S0022-5223(26)01147-5/fulltext">Factors Associated with Acute Intestinal Ischemia after Cardiac Surgery: A Propensity Score-matched Study</a></strong></p><p>R&#248;mer V, Holbek BL, Linde JJ, Brandtz&#228;g A, Resch T et al.</p><p>JCTVS. 2026, Jul 14. <span>Online ahead of print </span><strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.cureus.com/articles/489638-cardiopulmonary-bypass-circuit-tubing-rupture-during-unplanned-conversion-from-off-pump-coronary-artery-bypass-graft-procedure-a-case-report#!/">Cardiopulmonary Bypass Circuit Tubing Rupture During Unplanned Conversion From Off-Pump Coronary Artery Bypass Graft Procedure: A Case Report.</a></strong></p><p>Ansari AR, Cote F, Hadaway C.</p><p>Cureus. 2026 May 20;18(5):e109284 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.mdpi.com/2077-0383/15/12/4547">Does Inflammatory Prognostic Index Predict Postoperative Outcomes in Coronary Artery Bypass Grafting?</a></strong></p><p>Karaarslan M, Beyazal OF, Temizturk Z, Cevik B, Kayalar N, Yanartas M.</p><p>J Clin Med. 2026 Jun 11;15(12):4547 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.mdpi.com/2077-0383/15/12/4424">Expanding the Boundaries of Minimally Invasive Cardiac Surgery: Initial Experience with Multivalve Procedures.</a></strong></p><p>Karolak W, Sta&#324;ska A, Tomczyk I, Klapkowski A.</p><p>J Clin Med. 2026 Jun 8;15(12):4424 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.mdpi.com/2075-1729/16/6/1026">Preoperative Transcranial Doppler Findings and Postoperative Delirium After Cardiac Surgery in Elderly Patients: A Prospective Observational Study.</a></strong></p><p>Bergmann A, Ruzhyn Y, Wiesemann J, Hulde N, Fliegenschmidt J et al.</p><p>Life (Basel). 2026 Jun 19;16(6):1026 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(26)00471-4/abstract">Incidence and Characteristics of Residual Heparin Effect in Cardiothoracic Surgical Patients using Sonorheometry Clot Time Ratio.</a></strong></p><p>Marche CA, Knio ZO, Nguyen CT, Khan J, McNeil JS et al.</p><p>J Cardiothorac Vasc Anesth. 2026 May 30. Online ahead of print</p><p><strong><a href="https://link.springer.com/article/10.1007/s13239-026-00845-x">A Trends Analysis and Scoping Review: Minimal Invasive Extracorporeal Circulation.</a></strong></p><p>Hem&#351;inli D, Karaki&#351;i SO, K&#305;l&#305;&#231; H.</p><p>Cardiovasc Eng Technol. 2026 Jun 25. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://cvja.co.za/journal/cvja-2026-011/">The Early-term Effects of the Minimally Invasive Extracorporeal Circulation on Atrial Fibrillation Development in Patients Who Underwent Coronary Artery Bypass Grafting.</a></strong></p><p>Yilmaz S, Ayd&#305;n E, Kele&#351; BO.</p><p>Cardiovasc J Afr. 2026 Jun 5;37(2):203-207 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1007/s11748-026-02341-4">A Non-invasive and Simple Method to Assess Incomplete Aortic Cross-clamping during Cardiovascular Surgery with Cardiopulmonary Bypass.</a></strong></p><p>Minami K, Hiraoka A, Oshita T, Muraki R, Arimichi M.</p><p>Gen Thorac Cardiovasc Surg. 2026 Jun 24. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://journals.sagepub.com/doi/10.1177/02676591261462292">Hydrogen Ion (pH) and Gas Behavior during Deep Hypothermic Cardiopulmonary Bypass: Physiology and Clinical Implications.</a></strong></p><p>Diop S, Thes J, Kassab MC, Mounier R.</p><p>Perfusion. 2026 Jun 22. Online ahead of print</p><p><strong><a href="https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2026.1834632/full">Predictive Value of Multimodal Neurological Monitoring in the Postoperative Neurological Dysfunction after Cardiovascular Surgery with Cardiopulmonary Bypass.</a></strong></p><p>Zou M, Tan X, Zhang X, Yi M, Xiang Y, Wan P.</p><p>Front Neurol. 2026 Jun 4;17:1834632 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2026.1843167/full">Microcirculation Dysfunction and Cardioprotection in Cardiac Surgery with Cardiopulmonary Bypass: Mechanisms, Monitoring, and Therapeutic Strategies.</a></strong></p><p>Zheng C, Muir K, Kaushik H, Yalamanchili K, Zahiri K et al.</p><p>Front Cardiovasc Med. 2026 Jun 5;13:1843167 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s13019-026-04458-2">Precision Neuroprotection in Cardiac Surgery: A Structured Narrative Review of Multimodal, Data-driven Perioperative Care.</a></strong></p><p>Hamza M, Zafarullah M, Mujtaba M, Javaid MH, Butt AI et al.</p><p>J Cardiothorac Surg. 2026 Jun 21. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.sciencedirect.com/science/article/pii/S0022522326000735">Multidisciplinary Blood Conservation Practices for Transfusion-free Congenital Heart Surgery.</a></strong></p><p>Carrillo SA, Chenault K, Naguib AN, Voss J, Kelly M et al.</p><p>J Thorac Cardiovasc Surg. 2026 Jul;172(1):209-215</p><p><strong><a href="https://journals.sagepub.com/doi/full/10.1177/17504589261454168">The Hidden Myocardium: Why Intraoperative Hypotension Should be Treated as Myocardial Injury Prevention Rather Than a Transient Anaesthetic Variable.</a></strong></p><p>Burmeister JR, Jawad M, Metzger T, Zazay I, Mansoor M.</p><p>J Perioper Pract. 2026 Jun 2. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://journals.physiology.org/doi/full/10.1152/ajpheart.00016.2026">In Vivo Evidence of Blood Flow Slippage: Failure of the No-slip Boundary Condition Assumption.</a></strong></p><p>Jarol&#237;mov&#225; A, Hron J, T&#367;ma K, Chabiniok R, M&#225;lek J, Rajagopal K.</p><p>Am J Physiol Heart Circ Physiol. 2026 Jul 1;331(1):H301-H317 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.bjanaesthesia.org/article/S0007-0912(26)00120-0/fulltext">Physiology, Monitoring, and Optimisation of Perioperative Tissue Oxygenation: A Narrative Review.</a></strong></p><p>Meier J, Lasocki S, Meybohm P, Filipescu D, Haas T et al.</p><p>Br J Anaesth. 2026 Jun;136(6):1761-1775 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.sciencedirect.com/science/article/pii/S1052514926000018">Vascular and Hematologic Disorders.</a></strong></p><p>Nagornaya N, Aristizabal J, McKinney A, Saigal G.</p><p>Neuroimaging Clin N Am. 2026 Aug;36(3):475-493</p><p></p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://lucpuis.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">Tiny Perfusion Letter is a reader-supported publication. To receive new posts, consider becoming a free or paid subscriber</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div><p></p><p></p>]]></content:encoded></item><item><title><![CDATA[Tiny Perfusion Letter #824]]></title><description><![CDATA[Tiny Perfusion Letter]]></description><link>https://lucpuis.substack.com/p/tiny-perfusion-letter-824</link><guid isPermaLink="false">https://lucpuis.substack.com/p/tiny-perfusion-letter-824</guid><dc:creator><![CDATA[Luc Puis]]></dc:creator><pubDate>Tue, 14 Jul 2026 12:02:45 GMT</pubDate><enclosure url="https://substackcdn.com/image/fetch/$s_!Fa70!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fa2c04eb5-9a38-4ec1-99c4-a1745b246f8e_640x640.png" length="0" type="image/jpeg"/><content:encoded><![CDATA[<h1>Tiny Perfusion Letter</h1><p>They say life can be a rollercoaster</p><p>And every now and then, it feels like you&#8217;re stuck going downhill, when all the fun happens and you&#8217;re moving rapidly, turning sharply and go a little uphill, to move down again fast&#8230; Whoopie</p><p>While you&#8217;re in that situation, you sometimes go so fast that you can&#8217;t see what is happening next to you, or you don&#8217;t have the time to do what you usually do</p><p>We guess that&#8217;s why it is that we haven&#8217;t gotten to a TPL lately, which gives <strong>YOU</strong>, the reader, a break, but also means that <strong>WE</strong> at TPL would like to catch up&#8230;</p><p>Anyway, a lot of words to tell you that we&#8217;re having a loaded edition, once again</p><p>#enjoyandshare</p><p></p><p></p><p class="button-wrapper" data-attrs="{&quot;url&quot;:&quot;https://lucpuis.substack.com/?utm_source=substack&utm_medium=email&utm_content=share&action=share&quot;,&quot;text&quot;:&quot;Share Tiny Perfusion Letter&quot;,&quot;action&quot;:null,&quot;class&quot;:null}" data-component-name="ButtonCreateButton"><a class="button primary" href="/__u/lucpuis.substack.com/?utm_source=substack&amp;utm_medium=email&amp;utm_content=share&amp;action=share"><span>Share Tiny Perfusion Letter</span></a></p><p></p><p><strong><a href="https://link.springer.com/article/10.1186/s13019-026-04309-0">Preoperative IV Iron and Postoperative Blood Transfusion Reduction in Non-anaemic Patients Undergoing Cardiac Surgery: A Systematic Review and Meta-analysis of RCTs.</a></strong></p><p>Murad ZA, Lahcen AA, Alkhawam M, Elbasosy MY, Abdelhamid MO et al.</p><p>J Cardiothorac Surg. 2026 Jun 6. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s12872-026-06040-z">Association between Intrarenal Venous Flow and Postoperative Acute Kidney Injury in Cardiac Surgery Patients following Cardiopulmonary Bypass: A Prospective Cohort Study.</a></strong></p><p>Zhao J, Li Z, Wang W, Fu S, Fu Q, Fu S.</p><p>BMC Cardiovasc Disord. 2026 Jun 2. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.annalsthoracicsurgeryshortrep.org/article/S2772-9931(26)00223-8/fulltext">Role of Sex Hormones in Early Neurocognitive Decline After Cardiac Surgery: An Exploratory Analysis.</a></strong></p><p>Zheng CR, Stanley ME, Sawka DM, Ehsan A, Sodha NR, Sellke FW.</p><p>Ann Thorac Surg Short Reports. 2026 May 17. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://ject.edpsciences.org/articles/ject/full_html/2026/02/ject250093/ject250093.html">Considerations to Practice a Safe and Minimal Administration of Heparin and Protamine during Cardiopulmonary Bypass.</a></strong></p><p>Lee MH, Shann KG, Rosenthal T.</p><p>J Extra Corpor Technol. 2026 Jun;58(2):164-171 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.ovid.com/jnls/asaiojournal/fulltext/10.1097/mat.0000000000002754~quantitative-cerebral-perfusion-monitoring-using">Quantitative Cerebral Perfusion Monitoring Using Transit-Time Flow Measurement During Neonatal Aortic Arch Surgery: A Case Report.</a></strong></p><p>Orioli V, Careddu L, Agulli M, Sperandeo F, Berardi M, Mangerini VF, Angeli E.</p><p>ASAIO J. 2026 Jun 9. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.nejm.org/doi/full/10.1056/NEJMra2506021">Antidotes for Anticoagulation Reversal.</a></strong></p><p>Rocca B, Ten Cate H.</p><p>N Engl J Med. 2026 Jun 11;394(22):2235-2254</p><p><strong><a href="https://www.sciencedirect.com/science/article/pii/S2616420526000083">Evidence-based Clinical Applications of Minimal Invasive Extracorporeal Circulation: From Pathophysiological Protection to a Precision Perfusion Platform.</a></strong></p><p>Xiong H, Chang L, Yang Y, Chen T, Jin Z, Chen D.</p><p>ECLS. 2026;1(1):48-57 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.sciencedirect.com/science/article/pii/S152229422500087X">Beating Heart Implantation: A Comprehensive Technical Perspective</a></strong></p><p>Elde S, Krishnan A, Liou KS, Fawad M, McNulty J et al.</p><p>Oper Tech Thor Cardiovasc Surg. 2026;31(2):80-90 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://academic.oup.com/eurheartj/advance-article-abstract/doi/10.1093/eurheartj/ehag455/8705589">Accelerated Epigenetic Ageing in Congenital Heart Disease: The AccelerAGE Study.</a></strong></p><p>Tournoy TK, Daelman B, Demulier L, Brooke RT, Van De Bruaene A et al.</p><p>Eur Heart J. 2026 Jun 11. Online ahead of print</p><p><strong><a href="https://associationofanaesthetists-publications.onlinelibrary.wiley.com/doi/10.1111/anae.70125">Time of Day of Cardiac Surgery and Postoperative Outcomes In the UK: A Secondary Analysis of Linked National Datasets.</a></strong></p><p>Kitchen G, Thomas K, Felton T, Durrington H, Blaikley J et al.</p><p>Anaesthesia. 2026 Jun;81(6):775-782 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jtcvs.org/article/S0022-5223(26)00120-0/fulltext">Ethical Leadership in Cardiothoracic Surgery in an Era of Consolidation: A Framework for Trust, Transparency, and Workforce Stability.</a></strong></p><p>Shuhaiber J.</p><p>J Thorac Cardiovasc Surg. 2026 May;171(5):1169-1176 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://journals.sagepub.com/doi/10.1177/02184923261458087">Hemodynamic Principles of Arterial Cannulation: Orientation, Wall Shear Stress, Turbulence, Plaque Destabilization, and Cerebral Microembolization.</a></strong></p><p>Condello I, Dell&#8217;Aquila M, El Dsouki Y, Condello S, Falco G et al.</p><p>Asian Cardiovasc Thorac Ann. 2026 Jul;34(6):551-559</p><p><strong><a href="https://www.mdpi.com/2077-0383/15/11/4124">Side-Clamping Versus Single Cross-Clamping in On-Pump CABG: Impact on Early Hematologic Outcomes and Blood Conservation.</a></strong></p><p>&#214;nta&#351; H, G&#246;z&#252;a&#231;&#305;k R&#252;zgar AA.</p><p>J Clin Med. 2026 May 27;15(11):4124 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(26)00346-0/abstract">Advances in Cardiovascular Pharmacotherapy. VIII. Angiotensin II in Vasodilatory Shock.</a></strong></p><p>Pagel PS, Hang D, Freed JK, Crystal GJ.</p><p>J Cardiothorac Vasc Anesth. 2026 Apr 1. Online ahead of print</p><p><strong><a href="https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2026.1735292/full">Evaluation of Nosocomial Infections after Congenital Heart Surgery in Children: a Comprehensive Analysis Including the Systemic Immune-inflammation Index.</a></strong></p><p>Tak S, Demirda&#287; TB, &#304;riz E, Yi&#287;iter EN, Shide IAA et al.</p><p>Front Pediatr. 2026 May 26;14:1735292 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2026.1811178/full">Perioperative Immune Dynamics during Cardiopulmonary Bypass and Association with Major Adverse Postoperative Events.</a></strong></p><p>Cheng Z, Liao X, Wu J, Yang P, Wu Q et al.</p><p>Front Cardiovasc Med. 2026 May 26;13:1811178 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://journals.sagepub.com/doi/10.1177/21501351261449205">Perioperative Normoxia Versus Hyperoxia in Cyanotic Congenital Heart Surgery: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.</a></strong></p><p>Gon&#231;alves LB, Delgado LM, Oliveira RENDN, Carvalho E&#193;, Loftin M, Ten&#243;rio DF.</p><p>World J Pediatr Congenit Heart Surg. 2026 Jun 11. Online ahead of print</p><p><strong><a href="https://www.sciencedirect.com/science/article/pii/S0952818026001388">Exploring Carboxyhemoglobin as a Predictive Marker of Hemolysis-related CSA-AKI.</a></strong></p><p>Terrenghi S, Duceau B, Dureau P, Campeanu A, Djavidi N et al.</p><p>J Clin Anesth. 2026 Jun 10;113:112260. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.spandidos-publications.com/10.3892/br.2026.2162">Cognitive Dysfunction after Cardiac Surgery: A Systematic Review and Meta-analysis On the Mini-mental State Examination Findings.</a></strong></p><p>Cheng H, Yasen Y, Cheng X, Hu Z, Li X et al.</p><p>Biomed Rep. 2026 May 26;25(1):89 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://journals.co.za/doi/abs/10.5830/CVJA-2023-006">Effect of Different Priming Fluids on Extravascular Lung Water, Cell Integrity and Oxidative Stress in Cardiopulmonary Bypass Surgery.</a></strong></p><p>Ulug&#246;l H, Can MG, Aksu U, Vardar K, &#214;kten M, Toraman F.</p><p>Cardiovasc J Afr. 2024 May-Aug 1;35(2):70-74</p><p><strong><a href="https://www.mdpi.com/2077-0383/15/11/4221">Multi-Output Machine Learning for Prediction of Postoperative Outcomes After Cardiac Surgery Using Patient Blood Management Biomarkers.</a></strong></p><p>Coelho H, Paup&#233;rio D, Silva F, Barbosa MI, Ribeiro P et al.</p><p>J Clin Med. 2026 May 29;15(11):4221 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://jamanetwork.com/journals/jama/fullarticle/2850177">Survivors of Cyanotic Congenital Heart Disease: A Review.</a></strong></p><p>Egidy Assenza G, O&#8217;Leary E, Brida M, Kwon M, Landzberg MJ.</p><p>JAMA. 2026 Jul 7;336(1):56-68 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.annalsthoracicsurgery.org/article/S0003-4975(26)00577-1/pdf">Management Algorithm for Vasoplegic Shock after Cardiac Surgery: An Interdisciplinary Collaboration.</a></strong></p><p>Chatterjee S, Ortoleva J, Arora RC, Dalton KR, Engelman DT et al.</p><p>Ann Thorac Surg. 2026 Jun 17. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.ovid.com/jnls/anesthesia-analgesia/abstract/10.1213/ane.0000000000007845~fibrinogenalbumin-ratio-and-outcome-in-adult-cardiac-surgery?redirectionsource=fulltextview">Fibrinogen/Albumin Ratio and Outcome in Adult Cardiac Surgery With Cardiopulmonary Bypass.</a></strong></p><p>Casalino S, Anguissola M, Barbaria A, Aloisio T, Baryshnikova E, Landi G, Ranucci M.</p><p>Anesth Analg. 2025 Nov 25. Online ahead of print</p><p><strong><a href="https://heart.bmj.com/content/early/2026/05/28/heartjnl-2025-327683.long">Comparison between Three Single-dose Cardioplegic Solutions in Myocardial Protection: Cardioplegia Trial - A Double-blind Randomised Clinical Trial.</a></strong></p><p>Lira KB, Delvaux RS, Spadini FA, Anschau F, Kopittke L et al.</p><p>Heart. 2026 May 28. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jacc.org/doi/10.1016/j.jacadv.2026.102745">Perioperative Metabolomic Profiling in Neonatal Cardiac Surgery Identifies a High-Risk Phenotype for Adverse Outcomes.</a></strong></p><p>Cooney SJ, Chinni BK, Graham EM, Russell M, McCrindle BW et al.</p><p>JACC Adv. 2026 May;5(5):102745 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.ovid.com/jnls/anesthesia-analgesia/abstract/10.1213/ane.0000000000008136~cardiopulmonary-bypass-effects-on-minimum-alveolar?redirectionsource=fulltextview">Cardiopulmonary Bypass Effects on Minimum Alveolar Concentration and Other Bypass Terminology.</a></strong></p><p>Grocott HP.</p><p>Anesth Analg. 2026 May 27. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.mdpi.com/1422-0067/27/10/4416">Plasma from Cardiac Surgery Patients Induces Endothelial and Tubular Epithelial Cell Damage: Potential Role in Acute Kidney Injury Development-A Preliminary Report.</a></strong></p><p>Grossini E, Esposito T, Venkatesan S, Ola Pour MM, Cantaluppi V et al.</p><p>Int J Mol Sci. 2026 May 15;27(10):4416 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.mdpi.com/2227-9067/13/5/668">The Gut Microbiome in Congenital Heart Disease: Dysbiosis, Intestinal Barrier Injury, and Translational Opportunities Across the Childhood-A Narrative Review.</a></strong></p><p>Luca AC, Mindru DE, Rosu ST, Diaconescu C, Rosu EV, &#538;arc&#259; E, Adumitr&#259;chioaiei H, Anton-Paduraru DT.</p><p>Children (Basel). 2026 May 11;13(5):668 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.ovid.com/jnls/cardiologyinreview/abstract/10.1097/crd.0000000000001330~the-role-of-glucagon-like-peptide-1-receptor-agonists-in?redirectionsource=fulltextview">The Role of Glucagon-Like Peptide-1 Receptor Agonists in Mediating Myocardial Resilience in Cardiac Surgery.</a></strong></p><p>Venkatesan A, Martin A, Katragadda N, Tsui S, Otten M et al.</p><p>Cardiol Rev. 2026 May 25. Online ahead of print</p><p><strong><a href="https://jtd.amegroups.org/article/view/116820/html">Protamine Dosing in Cardiac Surgery: Method is Key.</a></strong></p><p>Beukers AM, Mansvelder FJ, Eberl S, Hermanns H.</p><p>J Thorac Dis. 2026 Apr 30;18(4):450 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://jtd.amegroups.org/article/view/116816/html">Push the Flow - Mind the Micro: Renal Microcirculation during High-flow Cardiopulmonary Bypass.</a></strong></p><p>Langouet E, Ouattara A, Tafer N, Villemain O.</p><p>J Thorac Dis. 2026 Apr 30;18(4):446 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://globalcardiologyscienceandpractice.com/index.php/gcsp/article/view/1041">Cardiopulmonary Bypass Complications and Their Predictors in Open-heart Surgery at a Tertiary Cardiac Care Facility in Tanzania.</a></strong></p><p>Luvakule AD, Gamba SF, Lugazia ER, Loth A.</p><p>Glob Cardiol Sci Pract. 2026 Apr 30;2026(2):e202611 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.tsoc.org.tw/upload/journal/1/20260531/acs-42-03-413.pdf">Challenges of Intra-Aortic Balloon Pump and Extracorporeal Membrane Oxygenation in Cardiogenic Shock: Real-World Outcomes.</a></strong></p><p>Wang WT, Lee CY, Huang SS, Fung E, Huang PH et al.</p><p>Acta Cardiol Sin. 2026 May;42(3):413-428 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(26)00358-7/abstract">Con: Viscoelastic Testing Should Not Be Used Routinely but Selectively in Cardiac Surgery.</a></strong></p><p>Cameron M, Awad T.</p><p>J Cardiothorac Vasc Anesth. 2026 Apr 27. Online ahead of print</p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(26)00443-X/abstract">Pro: Point-of-care Viscoelastic Testing Should Be Routinely Used in All Cardiac Surgery Patients.</a></strong></p><p>Galhardo C Jr,, Sheriffdeen R.</p><p>J Cardiothorac Vasc Anesth. 2026 May 22. Online ahead of print</p><p><strong><a href="https://www.sciencedirect.com/science/article/pii/S0020748925002925">Fatigue Risk Management in Healthcare: A Scoping Literature Review.</a></strong></p><p>Fox S, Dall&#8217;Ora C, Young M.</p><p>Int J Nurs Stud. 2026 Feb;174:105282 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(26)00545-8/fulltext">Heparin Activity Following Titration-Guided Protamine Reversal After Cardiopulmonary Bypass: Impact on Postoperative Bleeding,</a></strong></p><p>Tornudd M, Ramstrom S, Escobar Kvitting JP, Alfredsson J, Lindahl TL, Berg S. </p><p>J Cardiothorac Vasc Anesth. 2026 Jun 30. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://journals.sagepub.com/doi/abs/10.1177/21501351261450531">Mortality and Risk Factors in Pediatric Cardiac Surgery for Congenital Heart Disease in Mexico.</a></strong></p><p>Leyva-L&#243;pez Y, Cerano-Fuentes JL, Calder&#243;n-Colmenero J, Cervantes-Salazar JL.</p><p>World J Pediatr Congenit Heart Surg. 2026 Jun 2. Online ahead of print</p><p><strong><a href="https://journals.sagepub.com/doi/10.1177/03913988261450135">Antithrombin and 20% Albumin as Treatment of Oxygenator High Pressures Excursion during Cardiopulmonary Bypass in Cardiac Surgery: A Case Report.</a></strong></p><p>Mandarano R, Pedevilla S, Annese F, Pessetti L, Squiccimarro E et al.</p><p>Int J Artif Organs. 2026 Jul;49(7):468-472</p><p><strong><a href="https://www.nature.com/articles/s41598-026-57088-y">Development of a Hemolysis Filter System for the Selective Removal of Free Hemoglobin, Haem and Iron from Blood Envisaged for Use in Extracorporeal Circuits.</a></strong></p><p>Naghavi N, Barbaro L, Griffiths MJ, Davidson S, Melley DD et al.</p><p>Sci Rep. 2026 Jul 1. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s13019-026-04444-8">TM and t-PAIC May be Possible Biomarkers to Predict Postoperative Infection after Cardiac Surgery with Cardiopulmonary Bypass.</a></strong></p><p>Wang L, Chen Q, Wu W, Long Y.</p><p>J Cardiothorac Surg. 2026 Jun 14. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s13019-026-04420-2">Association of Surgeon Sex with Postoperative Adverse Outcomes in Adult Cardiac Surgery: A Nationwide Cohort Study.</a></strong></p><p>Arnreiter M, Kaider A, Pljakova M, Angleitner P, Osipenko K et al.</p><p>J Cardiothorac Surg. 2026 Jun 13. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s13019-026-04447-5">Patient and Family-centered Concerns in Pediatric Cardiac Surgery: a Middle Eastern Perspective.</a></strong></p><p>Jha NK, Hassan AA, Elmahi M.</p><p>J Cardiothorac Surg. 2026 Jun 12. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s13019-026-04442-w">Timing Matters: Association of Persistent Postoperative Anemia with Adverse Outcomes in Cardiac Surgery.</a></strong></p><p>Zhang X, Nie Y, Zhang R, Zhang Q, Wang X.</p><p>J Cardiothorac Surg. 2026 Jun 12. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.sciencedirect.com/science/article/abs/pii/S1053077026003009">How To Dose Prothrombin Complex Concentrates in Bleeding Patients After Cardiac Surgery.</a></strong></p><p>Bolliger D, Mauermann E, Tanaka KA.</p><p>J Cardiothorac Vasc Anesth. 2026 Jul;40(7):1977-1979</p><p><strong><a href="https://www.sciencedirect.com/science/article/pii/S105307702600248X">Anticoagulation Monitoring Strategies During Cardiopulmonary Bypass in Patients With Antiphospholipid Syndrome: A Systematic Review.</a></strong></p><p>Yoshida S, Ishida O, Tsutsumi K.</p><p>J Cardiothorac Vasc Anesth. 2026 Jul;40(7):2004-2014 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://iopscience.iop.org/article/10.1088/1361-6579/ae674f">Perioperative Hypoxaemia Early Warning Based on High-frequency Waveform Fusion and Deep Learning.</a></strong></p><p>Wang C, Dong L, Yu M, Chen W, Liu B, Zhang G.</p><p>Physiol. Meas. 2026, 47(5):55017</p><p><strong><a href="https://www.ovid.com/jnls/asaiojournal/fulltext/10.1097/mat.0000000000002590~numerical-analyses-of-blood-pumps-under-realistic-operating">Numerical Analyses of Blood Pumps Under Realistic Operating Conditions.</a></strong></p><p>Klocker S, Grujic M, Sch&#246;fbeck R, Thamsen B, Torner B et al.</p><p>ASAIO J. 2026 Jun 1;72(6):477-485 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.frontiersin.org/journals/surgery/articles/10.3389/fsurg.2026.1863142/full">Association between Circulating Biomarkers of Endothelial Glycocalyx Degradation and Postoperative Acute Kidney Injury in Patients Undergoing Cardiac Surgery with Cardiopulmonary Bypass.</a></strong><a href="https://www.frontiersin.org/journals/surgery/articles/10.3389/fsurg.2026.1863142/full"> </a></p><p>Wang M, He M, Hong L, Shen Y, Wang, Sun Y.</p><p>Front. Surg. 2026 Jul 12;13:1863142 <strong>OPEN ACCESS</strong></p><p></p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://lucpuis.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">Tiny Perfusion Letter is a reader-supported publication. To receive new posts, consider becoming a free or paid subscriber</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div><p></p>]]></content:encoded></item><item><title><![CDATA[Tiny Perfusion Letter #823]]></title><description><![CDATA[Tiny Perfusion Letter]]></description><link>https://lucpuis.substack.com/p/tiny-perfusion-letter-823</link><guid isPermaLink="false">https://lucpuis.substack.com/p/tiny-perfusion-letter-823</guid><dc:creator><![CDATA[Luc Puis]]></dc:creator><pubDate>Wed, 01 Jul 2026 12:02:21 GMT</pubDate><enclosure url="https://substackcdn.com/image/fetch/$s_!Fa70!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fa2c04eb5-9a38-4ec1-99c4-a1745b246f8e_640x640.png" length="0" type="image/jpeg"/><content:encoded><![CDATA[<h1>Tiny Perfusion Letter</h1><p>Here, at TPL HQ, we are not against AI at all</p><p>But we are very skeptic of how it is used in certain ways, and how it can be a danger to self discovery, skill learning, mental health, independent thinking and also education</p><p>We believe that AI should be supporting education and <strong><a href="https://www.damienrayuela.com/en/journal/how-can-ai-enable-real-learning/">this interesting blog</a></strong> has done the research, and created a nice overview of that (ironically they used AI to make it, but only to make it look orderly, not to do the research), and gives solutions to how AI can enable real learning</p><p>Bottom line is: you&#8217;re going to have to put the work in, but it will pay off in the end</p><p>#enjoyandshare</p><p></p><p class="button-wrapper" data-attrs="{&quot;url&quot;:&quot;https://lucpuis.substack.com/?utm_source=substack&utm_medium=email&utm_content=share&action=share&quot;,&quot;text&quot;:&quot;Share Tiny Perfusion Letter&quot;,&quot;action&quot;:null,&quot;class&quot;:null}" data-component-name="ButtonCreateButton"><a class="button primary" href="/__u/lucpuis.substack.com/?utm_source=substack&amp;utm_medium=email&amp;utm_content=share&amp;action=share"><span>Share Tiny Perfusion Letter</span></a></p><p></p><p><strong><a href="https://www.annalsthoracicsurgeryshortrep.org/article/S2772-9931(26)00213-5/fulltext">From Fast-Track to Enhanced Recovery After Surgery: A Definitive Review of Two Generations of Recovery in Cardiac Surgery</a></strong></p><p>Engelman DT, Engelman RM.</p><p><span>Ann Thor Surg Short Rep. 2026 May 29. Online ahead of print </span><strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s12893-026-03899-9">Correlations between Intraparenchymal Cerebral Temperature and Peripheral Temperature Monitoring Sites during Rewarming after Deep Hypothermic Circulatory Arrest on Cardiopulmonary Bypass.</a></strong></p><p>Parmantier D, Erhlich T, Dan P, Piccoli J, Phamisith &#201; et al.</p><p>BMC Surg. 2026 Jun 4. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.sciencedirect.com/science/article/abs/pii/S1538783626003533">Management of Anticoagulation in Patients with Heparin-induced Thrombocytopenia Requiring Cardiac Surgery with Cardiopulmonary Bypass: Guidance from the ISTH SSC on Perioperative and Critical Care Haemostasis and Thrombosis.</a></strong></p><p>Pishko AM, Frere C, Maier CL, Levy JH, Connors JM.</p><p>J Thromb Haemost. 2026 Jun 4. Online ahead of print</p><p><strong><a href="https://www.sciencedirect.com/science/article/pii/S2352556826001281">Perioperative Management of Adult Sickle Cell Disease Patients Requiring Cardiac Surgery: A 25-year Experience In a Referral Center.</a></strong></p><p>De Roux Q, Zanoun N, Habibi A, Cherait C, Alessandri C et al.</p><p>Anaesth Crit Care Pain Med. 2026 Jun 3. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://smj.researchcommons.org/journal/vol47/iss2/17/">National Heart Center Perfusion Guidelines.</a></strong></p><p>Khouqeer FA, Albaradei AS, Jamjoom AA, Jabbad HH, Iskander KA et al.</p><p>Saudi Med J. 2026 Feb;47(2):336-401 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.sciencedirect.com/science/article/pii/S1053077026003897">Challenging Venous Cannulation Pre-Cardiopulmonary Bypass During Aortic Surgery: An Interesting TEE Finding.</a></strong></p><p>Toor AS, Andany AV, Cory JM, Price J, Foglia J.</p><p>J Cardiothorac Vasc Anesth. 2026 May 8. Online ahead of print</p><p><strong><a href="https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2026.1818646/full">Monitoring Unfractionated Heparin in ECMO and Cardiac Surgery: the Search for a Valid Reference Standard.</a></strong></p><p>Weber CF, Zacharowski K, Calatzis A, Lindner ML.</p><p>Front Med (Lausanne). 2026 May 14;13:1818646 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s12959-026-00880-7">Plasma PF4 is a Reliable Biomarker of Platelet Reactivity and Predictive of Bleeding Risk in DAPT Patients Undergoing Cardiac Surgery.</a></strong></p><p>de Bezieux JR, Amour J, Philippe A, Rancic J, Gendron N. et al.</p><p>Thromb J. 2026 Jun 3;24(1):55 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2026.1803092/full">High Inappropriate Red Blood Cell Transfusion Rate Despite Low Overall Use: A Real-world Multicenter Study in 43 Spanish Hospitals.</a></strong></p><p>Tamayo-Velasco &#193;, Llau JV, Colomina MJ, de la Varga-Mart&#237;nez O, Navarro-P&#233;rez R et al.</p><p>Front Med (Lausanne). 2026 May 14;13:1803092 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.sciencedirect.com/science/article/pii/S1521689625000497">The Role of Biomarkers in the Preoperative Evaluation of Cardiac Surgical Patients - A Narrative Review.</a></strong></p><p>Coverdale G, Camilleri M, Patteril M.</p><p>Best Pract Res Clin Anaesthesiol. 2025 Jun;39(2):90-94</p><p><strong><a href="https://www.tandfonline.com/doi/10.1080/00365513.2026.2681039">Reference Intervals for Haptoglobin in Neonates and Children 30 Days to 18 Years Old.</a></strong></p><p>El Maamari J, Karlaftis V, Braida C, Smith J, Matthews S et al.</p><p>Scand J Clin Lab Invest. 2026 Jun 2:1-7. Online ahead of print</p><p><strong><a href="https://link.springer.com/article/10.1186/s42234-026-00208-w">Effects of Transcutaneous Auricular Vagus Nerve Stimulation or Combined Vagal and Trigeminal Nerve Stimulation on Platelet Function and Laboratory Hemostasis Parameters in Healthy Human Subjects.</a></strong></p><p>Huston JM, Bravo-I&#241;iguez CE, Papoin J, Ahmad M, Le B et al.</p><p>Bioelectron Med. 2026 Jun 5;12(1):14 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://ject.edpsciences.org/articles/ject/full_html/2026/02/ject250055/ject250055.html">A Pilot Study of the Impact of Enhanced Cardiac Index Coupled with Pulsatile Flow on Goal Direct Perfusion during Cardiopulmonary Bypass.</a></strong></p><p>Bagherinasab M, Rezaei S, Moradi AR, Aghal B, Steele-Pruett J, Darban NH.</p><p>J Extra Corpor Technol. 2026 Jun;58(2):110-116 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s13019-026-04344-x">Perioperative Hyperoxia versus Normoxia during Cardiopulmonary Bypass in Adult Cardiac Surgery: a ystematic Review and Meta-analysis of Randomized Controlled Trials.</a></strong></p><p>AlSejari NY, Aljaber BH, Alyahya SA, Alharran AM, Abdul-Hafez HA, Alsubaiei AA.</p><p>J Cardiothorac Surg. 2026 Jun 10. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2026.1837462/full">Nomogram for Subsyndromal Delirium after Cardiac Surgery with Cardiopulmonary Bypass: a Retrospective Cohort Study.</a></strong></p><p>Lin M, Xiang Y, Luo T, Ren Y, Wang J, Wang X, Zeng L and Fan J (2026)  </p><p>Front. Med. 2026;13:1837462 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.annalsthoracicsurgery.org/article/S0003-4975(26)00344-9/abstract">The Society of Thoracic Surgeons 2026 Clinical Practice Guidelines for the Prevention and Treatment of New-Onset Postoperative Atrial Fibrillation After Cardiac Surgery.</a></strong></p><p>Chatterjee S, Grant MC, Hui DS, Schwann TA, Alexander JH et al.</p><p>Ann Thorac Surg. 2026 Apr 18. Online ahead of print</p><p><strong><a href="https://www.thieme-connect.de/products/ejournals/abstract/10.1055/a-2812-7835">The Use of Intra-Aortic Balloon Pumping in Cardiac Surgery.</a></strong></p><p>Grieshaber P, Bauer A, B&#246;ning A, Groesdonk HV, Heringlake M et al.</p><p>Thorac Cardiovasc Surg. 2026 Jun;74(S 04):S99-S144</p><p><strong><a href="https://www.semthorcardiovascsurg.com/article/S1043-0679(26)00032-8/fulltext">Palliative Care Throughout the Entire Perioperative Pathway in Cardiovascular Surgery.</a></strong></p><p>Blum M, Schoenrath F, Ahn J, Bockbreder K, Ott S et al.</p><p>Semin Thorac Cardiovasc Surg. 2026 Jun 9. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s13019-026-04345-w">Patient Blood Management Protocol Reduces Allogeneic Transfusion, Morbidity, and Mortality in Coronary Artery Bypass Surgery.</a></strong></p><p>Alceu Dos Santos A, Hossne Junior NA, Gomes WJ, Guizilini S, da Silva GS et al.</p><p>J Cardiothorac Surg. 2026 Jun 5. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s13019-026-04340-1">Cardiopulmonary Bypass Elevates the Neutrophil-to-lymphocyte Ratio and Reduces Lymphocyte Counts: A Comparison of On-pump versus Off-pump CABG.</a></strong></p><p>Xia XF, Zhu YC, Zhang L, Bao R, Li D et al.</p><p>J Cardiothorac Surg. 2026 Jun 6. Online ahead of print <strong>OPEN ACCESS</strong></p><p></p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://lucpuis.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">Tiny Perfusion Letter is a reader-supported publication. To receive new posts, consider becoming a free or paid subscriber.</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div><p></p><p></p>]]></content:encoded></item><item><title><![CDATA[Tiny Perfusion Letter #822]]></title><description><![CDATA[Tiny Perfusion Letter]]></description><link>https://lucpuis.substack.com/p/tiny-perfusion-letter-822</link><guid isPermaLink="false">https://lucpuis.substack.com/p/tiny-perfusion-letter-822</guid><dc:creator><![CDATA[Luc Puis]]></dc:creator><pubDate>Wed, 24 Jun 2026 12:03:49 GMT</pubDate><enclosure url="https://substackcdn.com/image/fetch/$s_!Fa70!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fa2c04eb5-9a38-4ec1-99c4-a1745b246f8e_640x640.png" length="0" type="image/jpeg"/><content:encoded><![CDATA[<h1>Tiny Perfusion Letter</h1><p>Hmmm&#8230;, what if we&#8230;?</p><p>No&#8230;</p><p>And what about&#8230;?</p><p>Naaah&#8230;</p><p>Maybe we could&#8230;?</p><p>Nope.</p><p>We give up, let&#8217;s just get it started with&#8230;</p><p>#enjoyandshare</p><p></p><p class="button-wrapper" data-attrs="{&quot;url&quot;:&quot;https://lucpuis.substack.com/?utm_source=substack&utm_medium=email&utm_content=share&action=share&quot;,&quot;text&quot;:&quot;Share Tiny Perfusion Letter&quot;,&quot;action&quot;:null,&quot;class&quot;:null}" data-component-name="ButtonCreateButton"><a class="button primary" href="/__u/lucpuis.substack.com/?utm_source=substack&amp;utm_medium=email&amp;utm_content=share&amp;action=share"><span>Share Tiny Perfusion Letter</span></a></p><p></p><p><strong><a href="https://qualitysafety.bmj.com/content/early/2026/05/07/bmjqs-2026-020130">How Can We Prevent Clinical Deskilling When Using AI?</a></strong></p><p>Scott I, van der Vegt A, Douglas P.</p><p>BMJ Qual Saf. 2026 May 7. Online ahead of print</p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(26)00338-1/abstract">Risk Factor Analysis of Inadequate Heparin Response in Pediatric Cardiac Surgery.</a></strong></p><p>Swangwong S, Odegard K, Matte G, Nathan M, Emani S et al.</p><p>J Cardiothorac Vasc Anesth. 2026 Apr 16. Online ahead of print</p><p><strong><a href="https://journals.sagepub.com/doi/10.1177/02676591261452060">CytoSorb&#174; Haemoadsorption in High-risk Cardiac Surgery: A Focused Review with Proposed Tiered Patient Selection.</a></strong></p><p>Ohri SK.</p><p>Perfusion. 2026 May 14. Online ahead of print</p><p><strong><a href="https://journals.lww.com/transplantjournal/fulltext/9900/oncologic_safety_of_irradiated_only_autologous.1414.aspx">Oncologic Safety of Irradiated-only Autologous Blood Transfusion in Liver Transplantation for Hepatocellular Carcinoma: A Single-Center Cohort Study.</a></strong></p><p>Thierry G, Piette B, Navez M, Koch JN, Mangon A et al.</p><p>Transplantation. 2026 May 28. Online ahead of print</p><p><strong><a href="https://www.bjanaesthesia.org/article/S0007-0912(26)00273-4/fulltext">Patient Blood Management: a Systematic Review of Current International Guidelines.</a></strong></p><p>Dreher D, Honnef G, Zoidl P, Auinger D, Heuschneider L et al.</p><p>Br J Anaesth. 2026 May 11. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://journals.sagepub.com/doi/full/10.1177/02676591261452061">Microcirculatory Effects of Cardiopulmonary Bypass Primings in Coronary Artery Bypass Graft Surgery the Prime Randomised Clinical Trial for a Physiological Proof-of-principle.</a></strong></p><p>Beukers AM, Seegers JC, van Haasteren N, Brouwers M, Bosch RJ et al.</p><p>Perfusion. 2026 May 16. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.sciencedirect.com/science/article/pii/S2667100X26000265">Microcirculatory Response and Leukocyte Activation in Patients Undergoing Elective Cardiac Surgery with Cardiopulmonary Bypass.</a></strong></p><p>Favaron E, Ince C, Bosch RJ, Evers V, Hilty MP et al.</p><p>J Intensive Med. 2026 Feb 20;6(3):302-309 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://journals.sagepub.com/doi/10.1177/02676591261452056">Oxygenator Failures during Cardiopulmonary Bypass Lead to Associated Injury Patterns.</a></strong></p><p>Bradshaw JC, Bradshaw A, Agarwal R, Dontu V, Shirodkar S et al.</p><p>Perfusion. 2026 May 21. Online ahead of print</p><p><strong><a href="https://onlinelibrary.wiley.com/doi/10.1111/trf.70262">Next Generation Spray-dried On-demand Plasma: A Multicenter, Randomized, Dose-escalation, First-in-human Safety Study.</a></strong></p><p>Cancelas JA, Buckley L, Leitman SF, Nestheide S, Gingras L et al.</p><p>Transfusion. 2026 May 21. Online ahead of print</p><p><strong><a href="https://journals.lww.com/anesthesiology/abstract/9900/hydroxyethyl_starch_and_perioperative.1024.aspx">Hydroxyethyl Starch and Perioperative Complications: a Systematic Review and Meta-analysis.</a></strong></p><p>Sessler DI, Pradelli L, Povero M, Chappell D, Wang E.</p><p>Anesthesiology. 2026 May 20. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jacc.org/doi/10.1016/j.jacc.2026.04.018">The Male Survival Disadvantage: A Cardiovascular and Metabolic Puzzle.</a></strong></p><p>Krumholz HM.</p><p>J Am Coll Cardiol. 2026 May 26;87(20):2761-2763 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.sciencedirect.com/science/article/abs/pii/S221174582600026X">Prevention and Management of Hemolysis when Utilizing Mechanical Circulatory Support.</a></strong></p><p>Balthazar T, Carmeliet T, Raes M.</p><p>Interv Cardiol Clin. 2026 Jul;15(3):465-475</p><p><strong><a href="https://link.springer.com/article/10.1186/s12871-026-03929-2">Interpretable Machine Learning to Predict Postoperative Adverse Outcomes in Cardiac Surgery.</a></strong></p><p>Lei L, Qin D, Liu M, Ma D, Lei X et al.</p><p>BMC Anesthesiol. 2026 May 22. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s12871-026-03711-4">Crystalloid Fluids Choices during Cardiopulmonary Bypass, Outcomes of Acid-base and Lactate Levels in Cardio Surgery.</a></strong></p><p>Pabarjay M, Azarfarin R, Alizadeh-Ghavidel A, Hamidi SH, Bakhshandeh H et al.</p><p>BMC Anesthesiol. 2026 May 18. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s13019-026-04232-4">Outcomes after Extracorporeal Membrane Oxygenation Following the Norwood Procedure: a Systematic Review and Meta-analysis.</a></strong></p><p>Almehandi A, Altarkait A, Ali Y, Alhajri M, Alenezi M et al.</p><p>J Cardiothorac Surg. 2026 May 23. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s13019-026-04255-x">Association of the Red Cell Distribution Width to Total Serum Calcium Ratio with Severe AKI in Patients Undergoing Cardiac Surgery: a Retrospective Cohort Study Using the MIMIC-IV Database.</a></strong></p><p>Li X, Zheng K, He L, Zhang P, Lv M.</p><p>J Cardiothorac Surg. 2026 May 23. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s13019-026-04230-6">4-finger Technique for Retrograde Cardioplegia Cannula Insertion.</a></strong></p><p>Hammad W.</p><p>J Cardiothorac Surg. 2026 May 23;21(1):254 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s13019-026-04168-9">Use of Argatroban as Anticoagulation for Cardiopulmonary Bypass during Heart Transplantation: A Case Report.</a></strong></p><p>Faggioli M, Bacich D, Tessari C, Zanella F, Pittarello D et al.</p><p>J Cardiothorac Surg. 2026 May 18. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(25)01142-5/fulltext">Perioperative Inflammation and Immune Response in Anesthesia: Implications for Recovery and Postoperative Outcomes.</a></strong></p><p>Chen L.</p><p>J Cardiothorac Vasc Anesth. 2026 May;40(5):1511-1518</p><p><strong><a href="https://www.nature.com/articles/s41591-026-04438-y">AI-induced Never-skilling in Medical Education.</a></strong></p><p>Ke Y, Jin L, Ong JCL, Thirunavukarasu AJ, Car J et al.</p><p>Nat Med. 2026 Jun;32(6):1997-2006</p><p></p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://lucpuis.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">Tiny Perfusion Letter is a reader-supported publication. To receive new posts, consider becoming a free or paid subscriber.</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div><p></p>]]></content:encoded></item><item><title><![CDATA[Tiny Perfusion Letter #821]]></title><description><![CDATA[Tiny Perfusion Letter]]></description><link>https://lucpuis.substack.com/p/tiny-perfusion-letter-821</link><guid isPermaLink="false">https://lucpuis.substack.com/p/tiny-perfusion-letter-821</guid><dc:creator><![CDATA[Luc Puis]]></dc:creator><pubDate>Tue, 16 Jun 2026 12:02:44 GMT</pubDate><enclosure url="https://substackcdn.com/image/fetch/$s_!Fa70!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fa2c04eb5-9a38-4ec1-99c4-a1745b246f8e_640x640.png" length="0" type="image/jpeg"/><content:encoded><![CDATA[<h1>Tiny Perfusion Letter</h1><p>Research is exciting!</p><p>We&#8217;re sure not everyone would agree, because it&#8217;s probably the coming to an insight or confirmative result, or winning an award or applause after a presentation, that creates the excitement. But the road to it, the long hours of thinking, reading, planning, executing repetitive experiments and searching for a solution/answer - those are the less exciting parts of research. But also sometimes not&#8230; It can also be fun</p><p>When scanning the newsletters, blogs, tables of contents and whatsnot to curate yours very own TPL/TEL, we stumbled upon this curious title from a journal called Brain Communications (yup, that&#8217;s a thing). The title is: <strong><a href="https://academic.oup.com/braincomms/article/8/2/fcag064/8526011">Replication study: the case of disappearing teaspoons in a Scottish neuroscience department</a></strong></p><p>It&#8217;s Open Access and it&#8217;s about disappearing teaspoons - that&#8217;s all we&#8217;re going to say about it&#8230;</p><p>#enjoyandshare</p><p class="button-wrapper" data-attrs="{&quot;url&quot;:&quot;https://lucpuis.substack.com/?utm_source=substack&amp;utm_medium=email&amp;utm_content=share&amp;action=share&quot;,&quot;text&quot;:&quot;Share Tiny Perfusion Letter&quot;,&quot;action&quot;:null,&quot;class&quot;:null}" data-component-name="ButtonCreateButton"><a class="button primary" href="/__u/lucpuis.substack.com/?utm_source=substack&amp;utm_medium=email&amp;utm_content=share&amp;action=share"><span>Share Tiny Perfusion Letter</span></a></p><p></p><p><strong><a href="https://journals.sagepub.com/doi/10.1177/21501351261423189">The American Society of ExtraCorporeal Technology Standards and Guidelines for Pediatric and Congenital Perfusion Practice: 2025 Update.</a></strong></p><p>Oldeen ME, Striker CW, Angona R, Chianella DA, Capone C et al.</p><p>World J Pediatr Congenit Heart Surg. 2026 May 7. Online ahead of print</p><p><strong><a href="https://www.jtcvs.org/article/S0022-5223(26)00889-5/pdf">2026 American Association for Thoracic Surgery (AATS) Expert Consensus Document: Diagnosis and Management of Heparin-induced Thrombocytopenia in Cardiac Surgery Patients.</a></strong></p><p>Chatterjee S, Girardi NI, Crow J, Wieruszewski PM, Grant MC et al.</p><p>J Thorac Cardiovasc Surg. 2026 May 4. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.mdpi.com/2077-0383/15/8/3017">Perioperative Patient Blood Management: Evidence-Based Strategies for Surgeons and Anesthesiologists: A Narrative Review</a></strong></p><p>Nikolouzakis TK, Kantidakis EE, Crawford R, Pretorius R, Zaimakis ON, Chrysos E.</p><p>J Clin Med. 2026 Apr 15;15(8):3017 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://journals.sagepub.com/doi/10.1177/02184923261446677">Use of Extracorporeal Circulation in Multidisciplinary Approach and Replantation Strategies for Traumatic Limb Amputations: A Case Report.</a></strong></p><p>Bayram H, Durmaz A, Arikan AA, Yavuz S.</p><p>Asian Cardiovasc Thorac Ann. 2026 Jun;34(5):461-464</p><p><strong><a href="https://journals.sagepub.com/doi/10.1177/03913988261446074">Hemolysis Testing in Circulatory Support Pumps: Standards, Mock Loops, and Pulsatility.</a></strong></p><p>Park SM, Choi SW.</p><p>Int J Artif Organs. 2026 May;49(5):316-327</p><p><strong><a href="https://www.bjanaesthesia.org/article/S0007-0912(26)00162-5/abstract">Low Cardiac Index during Periods of Arterial Hypotension and Risk of Acute Kidney Injury in Cardiac Surgery.</a></strong></p><p>Goeddel LA, Koffman L, Zhou X, Hernandez M, Zhao A et al.</p><p>Br J Anaesth. 2026 May 6. Online ahead of print </p><p><strong><a href="https://www.ijbs.com/v22p4059.htm">Intestinal Ischemia/Reperfusion Injury: Mechanisms, Diagnosis, and Therapeutic Advances.</a></strong></p><p>Deng F, Sun QS, Xie S, Wu L, He SY et al.</p><p>Int J Biol Sci. 2026 Mar 30;22(8):4059-4073 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://journals.sagepub.com/doi/10.1177/02676591261427298">Prophylactic Temporary Mechanical Circulatory Support: The New Paradigm in Cardiac Surgery.</a></strong></p><p>Mariani S, Bari G, Meani P, Perazzo A, Kowalewski et al.</p><p>Perfusion. 2026 May;41(1_suppl):66S-82S <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jtcvs.org/article/S0022-5223(26)00852-4/fulltext">Low Intraoperative Oxygen Extraction during Heart Transplant Reduces Primary Graft Dysfunction Risk in Allografts with Prolonged Ischemic Time.</a></strong></p><p>Ahmad A, Wang CC, Bommareddi S, Trahanas JM, McGann KC et al.</p><p>J Thorac Cardiovasc Surg. 2026 May 3. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://journals.lww.com/anesthesia-analgesia/abstract/9900/nephrocheck_for_prediction_of_in_hospital_acute.1775.aspx">Nephrocheck for Prediction of In-Hospital Acute Kidney Injury and Major Adverse Kidney Events After Cardiac Surgery.</a></strong></p><p>Cheruku SR, Neyra JA, Trinh J, Hopson E, Nixon C et al.</p><p>Anesth Analg. 2026 May 5. Online ahead of print</p><p><strong><a href="https://link.springer.com/article/10.1186/s12871-026-03872-2">Topical Use of Tranexamic Acid for Antifibrinolysis in Cardiac Surgery with Cardiopulmonary Bypass: a Randomized Clinical Study.</a></strong></p><p>Tuerhong D, Li CX, Yan L.</p><p>BMC Anesthesiol. 2026 May 4. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.mdpi.com/2227-9059/14/4/837">The Role of Cytokines in Vascular Endothelial Glycocalyx Integrity and Impairment Following Open-Heart Surgery.</a></strong></p><p>Bati&#269;i&#263; L, &#262;urko-Cofek B, Taleska &#352;tupica G, Jenko M, Zdravkovi&#263; M et al.</p><p>Biomedicines. 2026 Apr 7;14(4):837 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2849735">Early Neurodevelopmental Outcomes in Children With Congenital Heart Disease.</a></strong></p><p>Seed M, Ilardi D, Rofeberg V, Ortinau C, Goldberg C et al.</p><p>JAMA Netw Open. 2026 Jun 1;9(6):e2615885 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://journals.lww.com/ejanaesthesiology/fulltext/2026/04000/optimal_metrics_for_assessing_the_climatic_impact.1.aspx">Optimal Metrics for Assessing the Climatic Impact of Volatile Anaesthetics.</a></strong></p><p>Coburn M, Hense A, Shine KP, Rex S, Kalmar AF, Laube JC.</p><p>Eur J Anaesthesiol. 2026 Apr 1;43(4):291-294 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(26)00300-9/fulltext">How To Dose Prothrombin Complex Concentrates in Bleeding Patients After Cardiac Surgery.</a></strong></p><p>Bolliger D, Mauermann E, Tanaka KA.</p><p>J Cardiothorac Vasc Anesth. 2026 Apr 10. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.sciencedirect.com/science/article/abs/pii/S1473050226000753">The Case for Washing Eed Blood Cells and Platelets - A Concise Review of Donors, Processes, and Products.</a></strong></p><p>Nguyen PL, Asante A, Refaai M, Masel D, Blumberg N.</p><p>Transfus Apher Sci. 2026 Jun;65(3):104443</p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(26)00331-9/fulltext">Impact of Restrictive Versus Liberal Oxygenation on Pulmonary Decline After Cardiac Surgery: A Substudy of the GLORIOUS Randomized Clinical Trial.</a></strong></p><p>Mikkelsen AD, Wiberg S, Schultz HHL, M&#248;ller-S&#248;rensen PH, H&#248;fsten D et al.</p><p>J Cardiothorac Vasc Anesth. 2026 Apr 14. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s41077-026-00439-6">Teaching Raters to See: A Faculty Development Innovation for Robust Assessment in Health Professions Education.</a></strong></p><p>Setnik L, Park YS, Buleon C, Szyld D, Rudolph J.</p><p>Adv Simul (Lond). 2026 May 5. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s13019-026-04253-z">Intraoperative Continuous Noninvasive Hemoglobin Monitoring in Patients Undergoing Thoracic Surgery.</a></strong></p><p>Mogahed MM, Alnoamani TS, Elkahwagy MS.</p><p>J Cardiothorac Surg. 2026 May 9;21(1):220 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s13019-026-04188-5">Association of Serum Lactate and One-year Mortality among Women with Coronary Artery Bypass Grafting Surgery: Filling Gaps in Female.</a></strong></p><p>Zhang R, Zhang K, Li B.</p><p>J Cardiothorac Surg. 2026 May 6. Online ahead of print <strong>OPEN ACCESS</strong></p><p></p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://lucpuis.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">Tiny Perfusion Letter is a reader-supported publication. To receive new posts, consider becoming a free or paid subscriber.</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div><p></p>]]></content:encoded></item><item><title><![CDATA[Tiny Perfusion Letter #820]]></title><description><![CDATA[Tiny Perfusion Letter]]></description><link>https://lucpuis.substack.com/p/tiny-perfusion-letter-820</link><guid isPermaLink="false">https://lucpuis.substack.com/p/tiny-perfusion-letter-820</guid><dc:creator><![CDATA[Luc Puis]]></dc:creator><pubDate>Tue, 09 Jun 2026 12:03:48 GMT</pubDate><enclosure url="https://substackcdn.com/image/fetch/$s_!Fa70!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fa2c04eb5-9a38-4ec1-99c4-a1745b246f8e_640x640.png" length="0" type="image/jpeg"/><content:encoded><![CDATA[<h1>Tiny Perfusion Letter</h1><p>Here is some news that caught our eyes &#129763; (that is the first cringe part of the news). It's a real eye-opener &#129763;.</p><p>It's not the news that&#8217;s cringe, it's the way we&#8217;re bringing it for your eyes to see &#129763;. Just close your eyes &#129763; and embrace it. <a href="https://news.miami.edu/stories/2025/07/paving-the-way-for-human-eye-transplants.html">Researchers at the University of Miami</a> have developed an eye-ECMO. It's a little box - called the eye-HOLDER<em> -</em> that is hooked to an actual ECMO to keep a donor eye perfused for implantation into a recipient. Just look at it &#129763;! There is also <a href="https://gizmo.md/2025/07/25/ecmo-inspired-technology-enables-viable-whole-eye-transplants/">a video here</a> that you can look at &#129763; and they have <a href="https://www.ophthalmologyscience.org/article/S2666-9145(26)00121-1/fulltext">published the initial cadaveric pilot here</a>. The researchers envision &#129763; that it would make eye transplantation possible in the foreseeable &#129763; future. Let's keep an eye open &#129763; for the first clinical application so we can actually believe it with our own eyes &#129763;. Wait and see&#8230;&#129763;</p><p>It is bold visions &#129763; like this that build the future&#8230;</p><p>You will need to see to believe it &#129763;</p><p>Don&#8217;t turn a blind eye now &#129763;</p><p>It&#8217;s all in the eye of the beholder &#129763;</p><p>OK&#8230;</p><p>#enjoyandshare</p><p></p><p class="button-wrapper" data-attrs="{&quot;url&quot;:&quot;https://lucpuis.substack.com/?utm_source=substack&utm_medium=email&utm_content=share&action=share&quot;,&quot;text&quot;:&quot;Share Tiny Perfusion Letter&quot;,&quot;action&quot;:null,&quot;class&quot;:null}" data-component-name="ButtonCreateButton"><a class="button primary" href="/__u/lucpuis.substack.com/?utm_source=substack&amp;utm_medium=email&amp;utm_content=share&amp;action=share"><span>Share Tiny Perfusion Letter</span></a></p><p></p><p><strong><a href="https://www.mdpi.com/2076-3425/16/4/412">A Systematic Review of How Cardiopulmonary Bypass Parameters Influence Electroencephalogram Signals.</a></strong></p><p>Bao H, Wang J, Cui Z, Zhu M, Chen W et al.</p><p>Brain Sci. 2026 Apr 13;16(4):412 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://journals.salviapub.com/index.php/gmj/article/view/3981">Comprehensive Coagulation Management in Cardiac Surgery: Anticoagulants, Heparin Resistance, Monitoring, and Bleeding Risks : Coagulation Management in Cardiac Surgery.</a></strong></p><p>Negargar S, Javanshir E.</p><p>Galen Med J. 2025 Nov 5;14:e3981 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.sciencedirect.com/science/article/abs/pii/S0039914026005680">A Highly Biocompatible Chip for Continuous Blood Electrolyte Detection Based on Hydrophilic Surface Modification.</a></strong></p><p>Yu H, Xu C, Tan Z, Sun C, Zhai X et al.</p><p>Talanta. 2026 Sep 1;307:129912 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://onlinelibrary.wiley.com/doi/10.1111/bjh.70509">Use of Andexanet Alfa: A British Society for Haematology Position Statement.</a></strong></p><p>Buka RJ, Arachchillage DJ, Bagot CN, Benson G, Bradbury CA et al.</p><p>Br J Haematol. 2026 Apr 25. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://journals.lww.com/aoca/fulltext/9900/thrombocytopenia_after_cardiac_surgery__a.26.aspx">Thrombocytopenia After Cardiac Surgery: A Single-Center Retrospective Study.</a></strong></p><p>Haszon D, Abdallah S, Jia Q, Lutz T, Santiago S et al.</p><p>Ann Card Anaesth. 2026 Apr 29. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://academic.oup.com/eurjcn/article/25/2/364/8488437">Harnessing Mobile Health to Support Recovery after Cardiac Surgery.</a></strong></p><p>Hayes M, Fredericks S.</p><p>Eur J Cardiovasc Nurs. 2026 Apr 29;25(2):364-365 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(26)00296-X/fulltext">Combined Platelet and Red Blood Cell Salvage During Cardiac Surgery.</a></strong></p><p>Bolliger D, Frei I.</p><p>J Cardiothorac Vasc Anesth. 2026 Apr 3. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.sciencedirect.com/science/article/abs/pii/S1053077026001436">TEAMing Up for Coronary Artery Bypass Grafting: Cardiac Anesthesiologists Driving Change.</a></strong></p><p>Shaygan L, Makkad B, Budd AN, Fermin L, Kucharski D, Kertai MD.</p><p>J Cardiothorac Vasc Anesth. 2026 Jun;40(6):1599-1605</p><p><strong><a href="https://www.sciencedirect.com/science/article/abs/pii/S1053077026001825">Influence of Human Factors on Coagulation Management in Cardiac Surgery: A Retrospective Analysis.</a></strong></p><p>Bachmann C, Di Primio T, Gauger MS, Hilber N, Biefer HRC et al.</p><p>J Cardiothorac Vasc Anesth. 2026 Jun;40(6):1638-1644</p><p><strong><a href="https://www.sciencedirect.com/science/article/pii/S1053077025012224">Influence of Non-Compressible Versus Compressible Underbody Forced-Air Warming Systems on Core Temperature in Off-Pump Cardiac Surgery.</a></strong></p><p>R&#246;sler O, Bakhtiary F, Bode C, Coburn M, Velten M, Piekarski F.</p><p>J Cardiothorac Vasc Anesth. 2026 Jun;40(6):1659-1667 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.sciencedirect.com/science/article/abs/pii/S1053077026001448">Unexpected Prolonged Activated Clotting Time During Abdominal Aortic Surgery Due to Low Factor XII Activity.</a></strong></p><p>Sugita Y, Hori Y, Nata Y, Sada Y, Yano K, Sakaguchi H.</p><p>J Cardiothorac Vasc Anesth. 2026 Jun;40(6):1795-1800</p><p><strong><a href="https://www.sciencedirect.com/science/article/abs/pii/S105307702600145X">The ISHLT Consensus Statement on the Perioperative Use of ECLS in Lung Transplantation: Highlights and Perioperative Implications.</a></strong></p><p>Wanar H, Weiner MM.</p><p>J Cardiothorac Vasc Anesth. 2026 Jun;40(6):1840-1848</p><p><strong><a href="https://www.sciencedirect.com/science/article/pii/S1053077026000455">A Retrospective Analysis of Thromboelastometry and Conventional Laboratory Values in Nonsurgical and Noncardiac Surgery Patients: Not What One Might Expect From Cardiac Surgery Data.</a></strong></p><p>Fischer P, L&#252;thy A, Bolliger D, Mauermann E, Frei I.</p><p>J Cardiothorac Vasc Anesth. 2026 Jun;40(6):1849-1857 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD014901.pub2/full">Early Versus Late Surgical Start Times for On-pump Cardiac Surgery.</a></strong></p><p>Liu Z, Penny-Dimri JC, Nagel M, Plummer M, Segal R et al.</p><p>Cochrane Database Syst Rev. 2026 Apr 28;4(4):CD014901</p><p><strong><a href="https://journals.lww.com/asaiojournal/abstract/9900/development_of_a_plasma_free_hemoglobin_adsorbing.947.aspx">Development of a Plasma Free Hemoglobin-Adsorbing Device for Extracorporeal Therapies.</a></strong></p><p>Butler M, Maywar A, Orizondo R, Federspiel W, Kim-Campbell N.</p><p>ASAIO J. 2026 May 1. Online ahead of print</p><p><strong><a href="https://openheart.bmj.com/content/13/1/e004011">Impact of Three-dimensional Heart Models on Surgical Planning and Outcomes in Congenital Heart Disease: a Systematic Review and Meta-analysis.</a></strong></p><p>Arero G, Jarsso G, Wako A, Fekadu D, Mardasa K, Godana H.</p><p>Open Heart. 2026 May 25;13(1):e004011 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://journals.sagepub.com/doi/full/10.1177/02676591261427298">Prophylactic Temporary Mechanical Circulatory Support: The New Paradigm in Cardiac Surgery.</a></strong></p><p>Mariani S, Bari G, Meani P, Perazzo A, Kowalewski M et al.</p><p>Perfusion. 2026 May;41(1_suppl):66S-82S <strong>OPEN ACCESS</strong></p><p><strong><a href="https://journals.sagepub.com/doi/full/10.1177/02676591261430620">The Role of the Perfusionist in the Extracorporeal Life Support Management: An International Survey.</a></strong></p><p>Scoppa C, Toscano D, Costa MC, Vercaemst L, Debeuckelaere G et al.</p><p>Perfusion. 2026 May;41(1_suppl):39S-50 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.sciencedirect.com/science/article/abs/pii/S0735109726062972">Obesity, Adipose Biology, and the Next Frontier in Cardiovascular Medicine</a></strong></p><p>Krumholz HM, Hines HH</p><p>JACC. 2026 Jun;87(21):2945-2947</p><p><strong><a href="https://link.springer.com/article/10.1007/s00101-026-01683-1">Perioperative Blood Management in Jehovah&#8217;s Witnesses.</a></strong></p><p>Piekarski F, Menzenbach J, Hilbert T, Hersch J, Schindler E et al.</p><p>Anaesthesiologie. 2026 May 4. Online ahead of print <strong>OPEN ACCESS</strong></p><p></p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://lucpuis.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">Tiny Perfusion Letter is a reader-supported publication. To receive new posts, consider becoming a subscriber.</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div><p></p>]]></content:encoded></item><item><title><![CDATA[Tiny Perfusion Letter #819]]></title><description><![CDATA[Tiny Perfusion Letter]]></description><link>https://lucpuis.substack.com/p/tiny-perfusion-letter-819</link><guid isPermaLink="false">https://lucpuis.substack.com/p/tiny-perfusion-letter-819</guid><dc:creator><![CDATA[Luc Puis]]></dc:creator><pubDate>Tue, 02 Jun 2026 12:04:08 GMT</pubDate><enclosure url="https://substackcdn.com/image/fetch/$s_!Fa70!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fa2c04eb5-9a38-4ec1-99c4-a1745b246f8e_640x640.png" length="0" type="image/jpeg"/><content:encoded><![CDATA[<h1>Tiny Perfusion Letter</h1><p>After two consecutive TPLs with 50 titles, we&#8217;re going to take a tiny breather and do a &#8220;normal&#8221; TPL (not that there is anything normal about it)</p><p>If you really crave more info to optimize the care for your patients, we recommend the <strong><a href="https://www.ctsnet.org/podcasts/">podcasts from CTSNet</a></strong>. There is <strong>The Cardiac Recovery Room</strong>, <strong>The Beat</strong>, <strong>The Atrium</strong> and <strong>The Lifeline</strong>. Enough for everyone! CTSNet has a <strong><a href="https://www.ctsnet.org/">renewed website</a></strong> and we recommend you to become a (free) member!</p><p>If you have never heard of CTSNet, we recommend spanking with a shore A 85 durometer 1/2#x3/32&#8221; tubing&#8230; A dual-stage venous cannula would also work&#8230;</p><p>Just kidding&#8230;</p><p>#enjoyandshare</p><p></p><p class="button-wrapper" data-attrs="{&quot;url&quot;:&quot;https://lucpuis.substack.com/?utm_source=substack&utm_medium=email&utm_content=share&action=share&quot;,&quot;text&quot;:&quot;Share Tiny Perfusion Letter&quot;,&quot;action&quot;:null,&quot;class&quot;:null}" data-component-name="ButtonCreateButton"><a class="button primary" href="/__u/lucpuis.substack.com/?utm_source=substack&amp;utm_medium=email&amp;utm_content=share&amp;action=share"><span>Share Tiny Perfusion Letter</span></a></p><p></p><p><strong><a href="https://link.springer.com/article/10.1186/s13019-026-04220-8">Predictive Value of Cerebral Oxygenation with Near Infrared Spectroscopy for In-hospital Mortality in Pediatric Congenital Heart Disease Surgery: a Retrospective Observational Study.</a></strong></p><p>Yilmaz H, Elcik D, Tuncay A.</p><p>J Cardiothorac Surg. 2026 Apr 26. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s13019-026-04233-3">Evaluation of Nursing Performance during Coronary Artery Bypass Grafting Surgeries Using Machine Learning Analysis of Surgical Videos: a Multicenter Retrospective Study.</a></strong></p><p>Tang Q, Richard SA, Peng S, Qiang H, Li J, Wang H.</p><p>J Cardiothorac Surg. 2026 Apr 24. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s13019-026-04110-z">Prehabilitation Clinic in Cardiac Surgery: Multidisciplinary Protocol for the Improvement of Postoperative Outcomes.</a></strong></p><p>Santarpino G, D&#8217;Anna V, Prencipe CM, Cavone M, Palisi G et al.</p><p>J Cardiothorac Surg. 2026 Apr 22. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://journals.sagepub.com/doi/abs/10.1177/08850666251321786">Systemic and Pulmonary Microcirculation, Double Microcirculation: From Basic Concepts to Treatment Key Points.</a></strong></p><p>Wang G, Deng Q, Wang J, Zhang Q, Lian H, Wang X.</p><p>J Intensive Care Med. 2026 May;41(5):365-380</p><p><strong><a href="https://www.nature.com/articles/s41586-026-10412-y">Engineering Tough Blood Clots for Rapid Haemostasis and Enhanced Regeneration.</a></strong></p><p>Jiang S, Bao G, Yang Z, Wu J, Yang X et al.</p><p>Nature. 2026 May;653(8115):723-730 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.mdpi.com/2075-4418/16/9/1375">Postoperative Bleeding Definitions as the Foundation of Hemostasis in Pediatric Cardiac Surgery.</a></strong></p><p>Karam O, Atchison C, Chegondi M.</p><p>Diagnostics (Basel). 2026 May 1;16(9):1375 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jocn-journal.com/article/S0967-5868(26)00210-9/fulltext">Cardiopulmonary Bypass Time, Intraoperative Hematocrit and Transfusion Predict Neurocognitive Decline in Patients undergoing Cardiac Surgery.</a></strong></p><p>Zheng CR, Kanuparthy M, Raker C, Sawka D, Cronkhite S et al.</p><p>J Clin Neurosci. 2026 Aug;150:112059 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2026.1750479/full">Immediate Postpartum Cardiac Surgery for Critical Congenital Heart Disease: Cardiopulmonary Bypass Management and Early Outcomes in 21 Neonates.</a></strong></p><p>Wang J, Miao N, Zhang X, Zhao X, Zhao J.</p><p>Front Cardiovasc Med. 2026 Apr 15;13:1750479 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2026.1765841/full">Gastrointestinal Complications after Cardiac Surgery: a Retrospective Case-control Study and Risk Score Development.</a></strong></p><p>Giambuzzi I, Bonalumi G, Messi P, Ballan G, Maccarana A et al.</p><p>Front Cardiovasc Med. 2026 Apr 15;13:1765841 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(26)00274-0/fulltext">Evaluating Four HIT Prediction Scores After Cardiac Surgery With Cardiopulmonary Bypass: A Comparative Study.</a></strong></p><p>Soyer G, Savard P, Guerci P, Hacquard MT, Jeanbert E et al.</p><p>J Cardiothorac Vasc Anesth. 2026 Apr 2. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(26)00276-4/abstract">Low-Dose Postoperative Amino Acid Infusion and Kidney Protection After Cardiac Surgery: A Before-and-After Observational Cohort Study.</a></strong></p><p>Ajello V, Franceschini G, Lorini A, Deiana C, Abate D et al.</p><p>J Cardiothorac Vasc Anesth. 2026 Mar 27. Online ahead of print</p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(26)00283-1/abstract">Impact of an Autotransfusion Device on Platelet Count and Transfusion Requirements in Cardiac Surgery: An Observational Study.</a></strong></p><p>Desfour M, Rigal JC, Boissier E, Guimbretiere G, Souab F et al.</p><p>J Cardiothorac Vasc Anesth. 2026 Apr 3. Online ahead of print</p><p><strong><a href="https://link.springer.com/article/10.1186/s13741-026-00687-0">FXII Decline during Cardiopulmonary Bypass and the Limits of Routine Coagulation Assays: a Prospective Observational Analysis.</a></strong></p><p>Thaler S, Aster I, Patton E, Voigt C, Peterss S et al.</p><p>Perioper Med (Lond). 2026 Apr 30;15(1):44 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s12871-026-03862-4">Intestinal Microbiota Dynamics in Postoperative Delirium following Cardiac Surgery with Cardiopulmonary Bypass: an Observational Study.</a></strong></p><p>Zhang S, Ma X, Zhang X, Zou B, Sun Y, Diao Y.</p><p>BMC Anesthesiol. 2026 Apr 29.Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.sciencedirect.com/science/article/abs/pii/S0952818026000954">Renal Pulsatility Index assessment by Intraoperative Doppler uUtrasound is Associated with Acute Kidney Injury after Cardiac Surgery: a Prospective Observational Study.</a></strong></p><p>Cheng X, Wang Q, Yuan Z, Zhang H, Wang L et al.</p><p>J Clin Anesth. 2026 Apr 28;112:112217. Online ahead of print</p><p><strong><a href="https://journals.lww.com/aoca/fulltext/9900/effect_of_albumin_concentration_and_timing_on.28.aspx">Effect of Albumin Concentration and Timing on Acute Kidney Injury After Adult Cardiac Surgery: A Systematic Review and Meta-analysis.</a></strong></p><p>Abo T, Umibe T, Nakano K, Tongu Y, Oya K.</p><p>Ann Card Anaesth. 2026 Apr 29. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://journals.lww.com/aoca/fulltext/9900/early_postoperative_complications_and_risk.30.aspx">Early Postoperative Complications and Risk Assessment in Cardiac Surgery: A Cohort Study.</a></strong></p><p>Vel&#225;squez JMR, Deras B.</p><p>Ann Card Anaesth. 2026 Apr 29. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s13019-026-04117-6">Effectiveness of Sodium Bicarbonate Ringer&#8217;s Solution as a Priming Fluid for Cardiopulmonary Bypass: a Propensity Score Matching Study.</a></strong></p><p>Xia Q, Song M, Lin F, Zhou C, Deng L.</p><p>J Cardiothorac Surg. 2026 Apr 28. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.cureus.com/articles/475203-establishing-cardiopulmonary-bypass-before-general-anesthesia-in-a-patient-undergoing-right-atrial-myxoma-resection#!/">Establishing Cardiopulmonary Bypass Before General Anesthesia in a Patient Undergoing Right Atrial Myxoma Resection.</a></strong></p><p>Beisenova K, Vogel A, Paladichuk S, Carter R, Wallen TJ, Mullen M.</p><p>Cureus. 2026 Mar 27;18(3):e105976 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s13019-026-04159-w">Early Oxygenator Failure during Cardiopulmonary Bypass with Preserved Neurological Outcome: a Case Report.</a></strong></p><p>Khan M, Naved SA, Rajput MZ, Shah MUA.</p><p>J Cardiothorac Surg. 2026 Apr 27. Online ahead of print <strong>OPEN ACCESS</strong></p><p></p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://lucpuis.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">Tiny Perfusion Letter is a reader-supported publication. To receive new posts, consider becoming a free or paid subscriber.</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div><p></p><p></p>]]></content:encoded></item><item><title><![CDATA[Tiny Perfusion Letter #818]]></title><description><![CDATA[Tiny Perfusion Letter]]></description><link>https://lucpuis.substack.com/p/tiny-perfusion-letter-818</link><guid isPermaLink="false">https://lucpuis.substack.com/p/tiny-perfusion-letter-818</guid><dc:creator><![CDATA[Luc Puis]]></dc:creator><pubDate>Wed, 27 May 2026 12:03:41 GMT</pubDate><enclosure url="https://substackcdn.com/image/fetch/$s_!Fa70!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fa2c04eb5-9a38-4ec1-99c4-a1745b246f8e_640x640.png" length="0" type="image/jpeg"/><content:encoded><![CDATA[<h1>Tiny Perfusion Letter </h1><p>As we said last week, we&#8217;re trying to catch up&#8230;</p><p>#enjoyandshare</p><p></p><p class="button-wrapper" data-attrs="{&quot;url&quot;:&quot;https://lucpuis.substack.com/?utm_source=substack&amp;utm_medium=email&amp;utm_content=share&amp;action=share&quot;,&quot;text&quot;:&quot;Share Tiny Perfusion Letter&quot;,&quot;action&quot;:null,&quot;class&quot;:null}" data-component-name="ButtonCreateButton"><a class="button primary" href="/__u/lucpuis.substack.com/?utm_source=substack&amp;utm_medium=email&amp;utm_content=share&amp;action=share"><span>Share Tiny Perfusion Letter</span></a></p><p></p><p></p><p><strong><a href="https://www.jem-journal.com/article/S0736-4679(25)00467-6/abstract">Comparison of Cadaveric Warming Rates in Accidental Hypothermia Between Continuous and Dwell Thoracic Lavage.</a></strong></p><p>O&#8217;Leary J, Davis C, Johnson J, Waasdorp C Jr, Gumayan JD, Lareau S.</p><p>J Emerg Med. 2026 May;84:59-65</p><p><strong><a href="https://www.mdpi.com/2077-0383/15/6/2403">Prognostic Value of Red Blood Cell Distribution Width in Predicting Acute Kidney Injury After Cardiac Surgery: A Retrospective Cohort Study.</a></strong></p><p>Marianello D, Puddu A, Biuzzi C, Fogagnolo A, Spadaro S et al.</p><p>J Clin Med. 2026 Mar 21;15(6):2403 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.mdpi.com/2227-9059/14/3/535">Estimated End-Tidal Sevoflurane Concentration to Maintain Optimal Anesthetic Depth During Cardiopulmonary Bypass: A Meta-Analysis.</a></strong></p><p>Lee SH, Kang TH, Yoo S, Kim K.</p><p>Biomedicines. 2026 Feb 27;14(3):535 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.mdpi.com/1648-9144/62/4/675">Silent Stroke in Adult Cardiac Surgery: Mechanisms, Clinical Impact, and Preventive Strategies.</a></strong></p><p>Condello I, Dell&#8217;Aquila M, Condello S, Falco G, Totaro A et al.</p><p>Medicina (Kaunas). 2026 Apr 1;62(4):675 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s12882-026-04922-0">Impacts of Preoperative Kidney Function and Acute Kidney Injury on Long-term Kidney Failure after Cardiac Surgery: a Registry-based Cohort Study.</a></strong></p><p>Keuskamp D, Davies CE, Baker RA, Polkinghorne KR, Reid CM et al.</p><p>BMC Nephrol. 2026 Apr 2;27(1):301 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC13054747/">Speech-Based Predictors of Nontechnical Skills Performance in Cardiac Surgery.</a></strong></p><p>Mendu S, Mishra S, Dias RD, Chaspari T, Zenati MA.</p><p>Proc Conf New Technol Comput Robot Assist Surg. 2025 Sep;2025:149-150 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/nbm.70284">Cerebral Hemodynamic Changes During Cardiac Surgery: A Feasibility MR Study in Piglets.</a></strong></p><p>Schulte DT, O&#8217;Gorman Tuura R, Richter H, Hofmann M, Del Chicca F et al.</p><p>NMR Biomed. 2026 May;39(5):e70284 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(26)00210-7/abstract">Rethinking Lactate in Cardiac Surgery and Intensive Care.</a></strong></p><p>Guzzi J, Salter R, Pettit S, Kelting T, Falter F, Perrino AC Jr.</p><p>J Cardiothorac Vasc Anesth. 2026 Mar 14. Online ahead of print</p><p><strong><a href="https://www.jtcvsopen.org/article/S2666-2736(25)00433-4/fulltext">Uncontrolled Hypertension Contributes to Vascular Permeability after Cardioplegic Arrest and Cardiopulmonary Bypass.</a></strong></p><p>Kanuparthy M, Stone CR, Manthana R, Kaushik H, Muir KC et al.</p><p>JTCVS Open. 2025 Dec 1;29:101541 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://journals.lww.com/jtrauma/abstract/9900/a_retrospective_observational_study_on_management.1312.aspx">A Retrospective Observational Study on Management of Penetrating Gunshot and Migrating Projectile Injuries to the Heart during the War in Ukraine.</a></strong></p><p>Maruniak S, Hutsuliak Y, Mokryk I, Zelenchuk O, Sudakevych S et al.</p><p>J Trauma Acute Care Surg. 2026 Apr 8. Online ahead of print</p><p><strong><a href="https://www.jtcvsopen.org/article/S2666-2736(25)00487-5/fulltext">The Value of Days Alive and Out of Hospital 30 Days after Surgery as an Outcome Measure in a Major Cardiac Surgical Center in Australia.</a></strong></p><p>Steel RP, Field JD, Dieleman JM.</p><p>JTCVS Open. 2025 Dec 11;29:101556 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jtcvsopen.org/article/S2666-2736(25)00427-9/fulltext">Long-term Cardiac Surgery Outcomes in Patients Receiving Dialysis and with Previous Kidney Transplantation: A National Registries Analysis.</a></strong></p><p>Keuskamp D, Davies CE, Baker RA, Polkinghorne KR, Reid CM et al.</p><p>JTCVS Open. 2025 Nov 24;29:101535 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jtcvsopen.org/article/S2666-2736(25)00398-5/fulltext">Modified Del Nido &#8220;Microplegia&#8221; Reduces Intraoperative, Postoperative, and Total Blood Products.</a></strong></p><p>Simon AB, Coffey T, Coffey P, Doddala B, Jones N et al.</p><p>JTCVS Open. 2025 Nov 11;29:101506 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.annalsthoracicsurgeryshortrep.org/article/S2772-9931(26)00134-8/fulltext">Beating Heart Removal of an Aortic Arch Thrombus Under Total Body Perfusion.</a></strong></p><p>Lotfalla A, Schreurs R, Heuts S, Bidar E.</p><p>Ann Thor Surg Short Reports. 2026 Apr 15. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://journals.sagepub.com/doi/10.1177/02676591261434526">Standardization of In-vitro Evaluation of Extracorporeal Life Support (ECLS) Devices for Research and Development.</a></strong></p><p>Arens J, Belliato M, Broman LM, Clauser JC, Donker DW et al.</p><p>Perfusion. 2026 Mar 13. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://journals.sagepub.com/doi/10.1177/02676591261429813">Brain Tissue Perfusion during Pulmonary Endarterectomy - The Impact of Controlled Regional Cooling.</a></strong></p><p>Veronesi R, Bozzini S, Dezza C, Pellegrini A, Rossini B et al.</p><p>Perfusion. 2026 Apr 16. Online ahead of print</p><p><strong><a href="https://www.mdpi.com/1422-0067/27/7/3336">Factor XII in Thrombosis and Thromboinflammation: From Molecular Biology to Clinical Translation.</a></strong></p><p>St&#281;pnicki J, Imiela AM, Szyma&#324;ska M, Miko&#322;ajczuk J, Pruszczyk P.</p><p>Int J Mol Sci. 2026 Apr 7;27(7):3336 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jacc.org/doi/10.1016/j.jaccas.2026.107170">Takotsubo Cardiomyopathy After Cardiac Surgery: A Hidden Menace.</a></strong></p><p>See SB, Chan IYH, Ho JYK, Wong RHL.</p><p>JACC Case Rep. 2026 May 13;31(19):107170 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.sciencedirect.com/science/article/pii/S0041134526001648">Flow Control and Oxygenation of Preservation Solution in Circulatory Determined Death Donors Undergoing Abdominal Normothermic Regional Perfusion.</a></strong></p><p>Antonini MV, Circelli A, La Manna G, Siniscalchi A, Cordella E et al.</p><p>Transplant Proc. 2026 May;58(4):632-635 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(26)00254-5/abstract">Association Between Core Body Temperature at the Time of Separation From Cardiopulmonary Bypass and Postoperative Acute Kidney Injury: A Retrospective Observational Study.</a></strong></p><p>Minami Y, Mukaida H, Sato G, Yasumoto H, Sugawara K et al.</p><p>J Cardiothorac Vasc Anesth. 2026 Mar 21. Online ahead of print</p><p><strong><a href="https://www.heartandlung.org/article/S0147-9563(26)00075-0/abstract">Predictors and Clinical Outcomes Associated with Prolonged Mechanical Ventilation Following Major Cardiac Surgery.</a></strong></p><p>Kang YA, Shin YS.</p><p>Heart Lung. 2026 Apr 13. Online ahead of print</p><p><strong><a href="https://link.springer.com/article/10.1007/s10877-026-01436-w">Intraoperative Respiratory Exchange Ratio to Predict Complications after Cardiopulmonary Bypass Surgery: a Retrospective Cohort Study.</a></strong></p><p>Riesemann S, Wachtendorf LJ, Braeuer BLP, Sahli SD, Paschold BS et al.</p><p>J Clin Monit Comput. 2026 Apr 15. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://peerj.com/articles/21055/">Factors Associated with Device-associated Health Care-associated Infections after Cardiac Surgery: a Matched Cohort Study.</a></strong></p><p>Yan M, Wang K, Liu S, Yan H, Kang B et al.</p><p>PeerJ. 2026 Apr 9;14:e21055 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s13019-026-04058-0">Hemofilters versus Hemodialyzers: Impacts on Cytokine Removal during Cardiopulmonary Bypass in Pediatric Cardiac Surgery: a Randomized Controlled Trial.</a></strong></p><p>Abdelazim AM, Alaaeldin B, Amer AM, Rizk A, Mahmoud D et al.</p><p>J Cardiothorac Surg. 2026 Apr 13;21(1):199 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://journals.lww.com/jnsa/abstract/9900/phase_specific_electroencephalography_monitoring_.224.aspx">Phase-Specific Electroencephalography Monitoring: A Dynamic Approach to Predict Postoperative Delirium During Aortic Surgery.</a></strong></p><p>Song Y, Lee HS, Han DW, Park S, Nam SB, Yang H, Bae J.</p><p>J Neurosurg Anesthesiol. 2026 Apr 14. Online ahead of print</p><p><strong><a href="https://link.springer.com/article/10.1186/s12871-026-03841-9">Development and External Validation of a Machine Learning Model for Predicting Severe Immediate Postoperative Complications in Adults Undergoing Cardiac Surgery.</a></strong></p><p>Cheun H, Ahn JH, Park JW, Ko SH, Shim JK et al.</p><p>BMC Anesthesiol. 2026 Apr 17. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s12872-026-05857-y">Impact of Eosinophil Levels on Postoperative Clinical Outcomes in Patients undergoing Extracorporeal Circulation: a Retrospective Cohort Study.</a></strong></p><p>Li L, Wang JM, Xu JC, Su QH, Shu R et al.</p><p>BMC Cardiovasc Disord. 2026 Apr 18. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jthjournal.org/article/S1538-7836(26)00220-5/abstract">Development of New Antithrombotic Drugs for Children (Part 1): Guidance from the ISTH SSC Subcommittee on Pediatric and Neonatal Thrombosis and Hemostasis and the Pedi-ATLAS Group.</a></strong></p><p>Goldenberg NA, Berkowitz SD, Betensky M, Holzhauer S, Ignjatovic V et al.</p><p>J Thromb Haemost. 2026 Apr 10. Online ahead of print</p><p><strong><a href="https://www.nature.com/articles/s44161-026-00802-w">Cardiovascular PIEZO Discovery Continues Apace to Reveal Myocardial Nerves Feeling Posture and Blood Loss.</a></strong></p><p>Beech DJ.</p><p>Nat Cardiovasc Res. 2026 Apr;5(4):286-288.</p><p><strong><a href="https://www.mdpi.com/2075-4426/16/2/69">Artificial Intelligence in Adult Cardiovascular Medicine and Surgery: Real-World Deployments and Outcomes.</a></strong></p><p>Magouliotis DE, Sicouri N, Ramlawi L, Baudo M, Androutsopoulou V, Sicouri S.</p><p>J Pers Med. 2026 Jan 30;16(2):69 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.semthorcardiovascsurg.com/article/S1043-0679(26)00019-5/fulltext">Preventing Stroke in Aortic Arch Operations.</a></strong></p><p>Ikeno Y, Tanaka A, Estrera AL.</p><p>Semin Thorac Cardiovasc Surg. 2026 Apr 22. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jhltopen.org/article/S2950-1334(26)00095-9/fulltext">Surgical Technique of Donation after Circulatory Death Heart Procurement Using Direct Procurement and Hypothermic Oxygenated Perfusion Preservation</a></strong></p><p>Vandendriessche K, Brouckaert J, Van de Voorde K, Gaublomme F, Degezelle K et al.</p><p>JHLT Open. 2026 Apr 22. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jhltopen.org/article/S2950-1334(26)00038-8/fulltext">Minimal Intraoperative Anticoagulation Strategy for Lung Transplantation with Preoperative Heparin-induced Thrombocytopenia.</a></strong></p><p>Bagrodia N, Alvarez AV, Gouchoe DA, Whitson BA, Henn MC, Choi K.</p><p>JHLT Open. 2026 Feb 9;12:100517 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.sciencedirect.com/science/article/pii/S0003497525010999">Arterial Cannulation and Brain Perfusion Strategies for Acute Type A Dissection in North America.</a></strong></p><p>Koprivanac M, Desai N, Stembal F, Chang SC, Habib RH et al.</p><p>Ann Thorac Surg. 2026 May;121(5):1059-1067 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1007/s13239-026-00822-4">Synthetic, Population-Based Virtual Patient Database Using a Digital Twin of the Cardiovascular System.</a></strong></p><p>W&#233;ber R, Viharos M, Csippa B, Gy&#252;rki D, Pa&#225;l G.</p><p>Cardiovasc Eng Technol. 2026 Apr;17(2):188-205 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1007/s10877-025-01400-0">Feasibility of Estimating Cardiac Indices Using Cardiac Surgery Anesthesia Records in a Multicenter Cohort.</a></strong></p><p>Balczewski EA, Mentz G, Singh K, Mathis MR.</p><p>J Clin Monit Comput. 2026 Jun;40(3):635-643 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1007/s10877-026-01412-4">Peripheral Perfusion Noninvasive Monitoring Technologies - a Literature and Patent Review.</a></strong></p><p>Orellana Plaza I, Dankelman J, Bakker J.</p><p>J Clin Monit Comput. 2026 Jun;40(3):673-686 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1007/s10877-025-01396-7">Program of Quality Improvement for Extracorporeal Blood Purification Therapies in the Intensive Care Unit.</a></strong></p><p>Cecchi M, Pomar&#232; Montin D, Fioccola A, Bocciero V et al.</p><p>J Clin Monit Comput. 2026 Jun;40(3):735-745 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1007/s10877-025-01406-8">A Cohort, Semi-Randomized, Open Label Quality Improvement Patient Blood Management (PBM) Comparison of Point of Care Viscoelastic Coagulation Monitors in Cardiac Surgery.</a></strong></p><p>Spiess BD, Burger M, R N MJM, R N SG, Garvan C et al.</p><p>J Clin Monit Comput. 2026 Jun;40(3):747-755 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.mdpi.com/2076-3271/14/2/182">Evolution of Femoral Cannulation Techniques in Minimally Invasive Mitral Valve Surgery: A 10-Year Experience.</a></strong></p><p>Schwarz J, Massoudy P, Harpa MM, Czesla M, Mogilansky C et al.</p><p>Med Sci (Basel). 2026 Apr 3;14(2):182 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.annalsthoracicsurgeryshortrep.org/article/S2772-9931(25)00284-0/fulltext">A 27-Year Comparative Analysis of Off-Pump and On-Pump Coronary Artery Bypass Grafting in Octogenarians.</a></strong></p><p>Comanici M, Nair A, Umakumar K, Marczin N, Bhudia SK, Raja SG.</p><p>Ann Thorac Surg Short Rep. 2025 Jul 31;4(1):38-42 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.scielo.cl/scielo.php?script=sci_arttext&amp;pid=S0034-98872026000200190&amp;lng=en&amp;nrm=iso&amp;tlng=en">The Effect of ABO Blood Groups and Rhesus Factor on Cardiac Surgery Performed with Cardiopulmonary Bypass.</a></strong></p><p>Ama&#231; B, Engin M, Hijazi A, Abanoz M.</p><p>Rev Med Chil. 2026 Feb;154(2):190-200 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://jnhrc.com.np/index.php/jnhrc/article/view/4652">Blood Lactate Clearance as a Predictor of Mortality in Children Undergoing Cardiac Surgery with Cardiopulmonary Bypass.</a></strong></p><p>Mahaju Bajracharaya S, Shrestha U, Amatya AG.</p><p>J Nepal Health Res Counc. 2026 Mar 24;23(4):638-645</p><p><strong><a href="https://www.sciencedirect.com/science/article/pii/S1441277226000177">The Effect of Intravenous Calcium Administration on Haemodynamics in Perioperative Cardiothoracic Surgery and Intensive Care: A Narrative Review.</a></strong></p><p>Miller A, Omassoli J, Simpson J, Brooks K, Almeida A et al.</p><p>Crit Care Resusc. 2026 Apr 18;28(2):100178 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://journals.sagepub.com/doi/10.1177/02676591261446139">Goal-directed Perfusion during Cardiopulmonary Bypass: Physiological Rationale, Clinical Evidence, and Critical Appraisal.</a></strong></p><p>Mukaida H, Minami Y.</p><p>Perfusion. 2026 Apr 20. Online ahead of print</p><p><strong><a href="https://journals.sagepub.com/doi/10.1177/02676591261446469">Modified Extracorporeal Circulation (mECC) for Enhanced Blood Conservation in Thoracoabdominal Aortic Surgery: A Single-center Experience.</a></strong></p><p>Sar&#305;cao&#287;lu MC, Ak&#231;a F, &#214;z&#231;&#305;nar E, Hasde A&#304;, Dikmen N et al.</p><p>Perfusion. 2026 Apr 23. Online ahead of print</p><p><strong><a href="https://www.annalsthoracicsurgeryshortrep.org/article/S2772-9931(25)00331-6/fulltext">The Current State and Challenges in Cardiothoracic Surgery in Latin America.</a></strong></p><p>Cubas WS, Vervoort D, Day&#225;n V, R&#237;os-Ortega J, Montes L.</p><p>Ann Thorac Surg Short Rep. 2025 Oct 6;4(1):329-333 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC13093145/">Evaluation of a Novel Intelligent Interruption Management System in High-Fidelity Simulated Cardiac OR to Improve Surgical Safety.</a></strong></p><p>Mendu S, Dias RD, Arney D, Ebnali RH, Conboy H et al.</p><p>Proc Conf New Technol Comput Robot Assist Surg. 2025 Sep;2025:151-152 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jocn-journal.com/article/S0967-5868(26)00210-9/fulltext">Cardiopulmonary Bypass Time, Intraoperative Hematocrit and Transfusion Predict Neurocognitive Decline in Patients undergoing Cardiac Surgery.</a></strong></p><p>Zheng CR, Kanuparthy M, Raker C, Sawka D, Cronkhite S et al.</p><p>J Clin Neurosci. 2026 Aug;150:112059 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s12872-026-05861-2">Coronary Slow Flow: Role of Systemic Inflammation and Biomarkers in its Pathophysiology.</a></strong></p><p>Flores MVM, Robledo AIU, Galarza FFG, L&#243;pez FKS, Aguirre HAD et al.</p><p>BMC Cardiovasc Disord. 2026 Apr 21. Online ahead of print <strong>OPEN ACCESS</strong></p><p></p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://lucpuis.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">Tiny Perfusion Letter is a reader-supported publication. To receive new posts, consider becoming a free or paid subscriber.</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div><p></p><p></p>]]></content:encoded></item><item><title><![CDATA[Tiny Perfusion Letter #817]]></title><description><![CDATA[Tiny Perfusion Letter]]></description><link>https://lucpuis.substack.com/p/tiny-perfusion-letter-817</link><guid isPermaLink="false">https://lucpuis.substack.com/p/tiny-perfusion-letter-817</guid><dc:creator><![CDATA[Luc Puis]]></dc:creator><pubDate>Tue, 19 May 2026 12:00:43 GMT</pubDate><enclosure url="https://substackcdn.com/image/fetch/$s_!Fa70!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fa2c04eb5-9a38-4ec1-99c4-a1745b246f8e_640x640.png" length="0" type="image/jpeg"/><content:encoded><![CDATA[<h1>Tiny Perfusion Letter</h1><p>We owe you an apology&#8230;</p><p>(Or maybe not? This is all voluntary and not-for-profit, exactly the reason why we haven&#8217;t heavily monetized this much-appreciated newsletter: we can do whatever we want)</p><p>We haven&#8217;t produced a TPL in a while, and that is all because of being busy (not just the daily busy, but the incredibly insane what-do-I-do-first, hyperbusy&#8230; (it was so busy, hyperbusy isn&#8217;t even in the dictionary)</p><p>That means articles have been piling up and we are really wanting to catch up</p><p>You&#8217;ll be getting a few TPLs that are longer than usual, but the premise is the same: you only read what you like, it might be a little more than usual</p><p>If you don&#8217;t feel like reading, here&#8217;s a great <strong><a href="https://is.gd/KaQ2AR">survey</a></strong> that we would like to promote, from Dr Tony Shackelford, CCP at MUSC:</p><blockquote><p>&#8220;We&#8217;ve been running a longitudinal perfusion practice survey since 2004. Four waves now &#8212; 2004, 2006, 2011, and 2026. The goal has always been the same: document how perfusion practice actually evolves over time, what perfusionists are actually doing at the bedside. Prime volumes, circuit configuration, blood conservation strategies, ECMO responsibility, GDP adoption, cannula selection &#8212; the real picture. The survey takes about 7 minutes, it&#8217;s completely anonymous, and you can take the survey <strong><a href="https://is.gd/KaQ2AR">here</a>&#8221;</strong></p></blockquote><p>To wind down from all that, here&#8217;s a little something to keep you distracted: <strong><a href="https://www.cosmicodometer.space/">The Cosmic Odometer</a></strong>&#8230; It also helps to relativize the fact that since we last published a TPL (or just taking that <strong><a href="https://is.gd/KaQ2AR">survey</a></strong>), a LOT, and also NOT MUCH has happened at the same time&#8230; It&#8217;s a bit mind-blowing, actually</p><p>Just like this&#8230;</p><p>#enjoyandshare</p><p></p><p class="button-wrapper" data-attrs="{&quot;url&quot;:&quot;https://lucpuis.substack.com/?utm_source=substack&amp;utm_medium=email&amp;utm_content=share&amp;action=share&quot;,&quot;text&quot;:&quot;Share Tiny Perfusion Letter&quot;,&quot;action&quot;:null,&quot;class&quot;:null}" data-component-name="ButtonCreateButton"><a class="button primary" href="/__u/lucpuis.substack.com/?utm_source=substack&amp;utm_medium=email&amp;utm_content=share&amp;action=share"><span>Share Tiny Perfusion Letter</span></a></p><p></p><p><strong><a href="https://journalaim.com/Article/aim-35112">Exploring the Role of Central Venous Pressure in Cardiac Surgery-Associated Acute Kidney Injury: A Comprehensive Scoping Review.</a></strong></p><p>Aligholizadeh M, Sangi S, Mesbah Kiaei M, Mohaghegh MR, Abbasi M, Aligholizadeh M.</p><p>Arch Iran Med. 2025 Dec 1;28(12):710-718 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://academic.oup.com/icvts/article/41/3/ivag081/8525330">Prolonged Systemic Inflammatory Response Syndrome Predicts Atrial Fibrillation After Cardiac Surgery.</a></strong></p><p>Viikinkoski E, Lehto J, Relander A, Jalkanen J, Gunn J et al.</p><p>Interdiscip Cardiovasc Thorac Surg. 2026 Mar 12;41(3):ivag081 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.frontiersin.org/journals/digital-health/articles/10.3389/fdgth.2026.1695494/full">Predicting Kidney Injury after Cardiac Surgery with Cardio-pulmonary Bypass Using Machine Learning.</a></strong></p><p>Fliegenschmidt J, Sasono G, Cabanillas Silva P, Meesseman L, Rezk M et al.</p><p>Front Digit Health. 2026 Feb 26;8:1695494 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(26)00123-0/fulltext">Weaning From Mechanical Ventilation in Cardiac Surgery Patients: Current Strategies, Monitoring Innovations, and Future Perspectives.</a></strong></p><p>Rauseo M, Cotoia A, Padovano FP, Squiccimarro E, Paparella D et al.</p><p>J Cardiothorac Vasc Anesth. 2026 Feb 11. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.australiancriticalcare.com/article/S1036-7314(26)00030-5/abstract">Nutrition Support Practices in Cardiothoracic Surgery Patients with Gastrointestinal Complications: An Observational Study.</a></strong></p><p>Davis C, Louis R, Asser I, Green M, Thatcher A et al.</p><p>Aust Crit Care. 2026 Apr;39(2):101560</p><p><strong><a href="https://www.mdpi.com/2077-0383/15/5/1887">The Association Between Early Postoperative Temperature Trajectories and Severe Acute Kidney Injury After Valvular Heart Surgery: A Retrospective Cohort Study.</a></strong></p><p>Cho JS, Suh S, Shim JK, Lee HS, Choi HW et al.</p><p>J Clin Med. 2026 Mar 1;15(5):1887 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.sciencedirect.com/science/article/pii/S0003497525012597">Radical Pericardiectomy and Use of Cardiopulmonary Bypass for Constrictive Pericarditis.</a></strong></p><p>Koprivanac M, Bauza K, Smedira N, Pettersson G, Unai S et al.</p><p>Ann Thorac Surg. 2026 Apr;121(4):871-880 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://journals.sagepub.com/doi/full/10.1177/02676591261438387">Normoxic versus Hyperoxic Reperfusion: A Retrospective Study of Ischemia-reperfusion Injury in Patients undergoing On-pump Coronary Artery Bypass Grafting.</a></strong></p><p>El Dsouki Y, Condello I, Gunertem OE, Yildirim A, Gunaydin S, Lorusso R.</p><p>Perfusion. 2026 Mar 21. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.sciencedirect.com/science/article/abs/pii/S0952818026000681">Dose-response Relationship between Cell Salvage Volume, Perioperative Transfusion Requirements, and Postoperative Clinical Outcomes in Cardiac Surgery: A Retrospective Cohort Study.</a></strong></p><p>Fein S, Aranbitski R, Shimon O, Krasulya B, Kashkush A et al. </p><p>J Clin Anesth. 2026 Apr;111:112190</p><p><strong><a href="https://onlinelibrary.wiley.com/doi/10.1002/pan.70173">Impact of Priming Volume Reduction on Hematocrit Retention in Pediatric Cardiopulmonary Bypass: A Retrospective Analysis.</a></strong></p><p>Hibino T, Okui Y, Toba Y, Kondo S, Ikegami H et al.</p><p>Paediatr Anaesth. 2026 Jun;36(6):703-713 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.sciencedirect.com/science/article/abs/pii/S0002870326000967">Design and Rationale of the Impella&#174;-protected Cardiac Surgery Trial (IMPACT): A Multicenter, Single-arm Pilot Study in High-risk Cardiac Surgery Patients.</a></strong></p><p>Goldstein DJ, Reichenspurner H, Vorovich E, Teuteberg J, Ramzy D et al.</p><p>Am Heart J. 2026 Jul;297:107434</p><p><strong><a href="https://www.mdpi.com/2075-4426/16/3/138">Volatile Anesthesia in Contemporary Cardiac Surgery: Clinical Implications, Organ Protection and Perspectives for Personalized Perioperative Care.</a></strong></p><p>Torre DE, Pirri C.</p><p>J Pers Med. 2026 Mar 1;16(3):138 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.mdpi.com/2308-3425/13/3/121">Early Prediction of Postoperative Peritoneal Dialysis Using Lung Ultrasound Scoring in Neonates After Cardiopulmonary Bypass.</a></strong></p><p>Tun&#231;el D, Geter S, &#350;ero L, K&#305;l&#305;&#231; Y, Okur N, Aldudak B.</p><p>J Cardiovasc Dev Dis. 2026 Mar 6;13(3):121 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://tjtcvs.org/articles/comparison-of-intermittent-antegrade-cardioplegia-and-antegraderetrograde-cardioplegia-in-cardiac-surgery-a-propensity-matched-analysis/doi/tjtcs.2026.28228">Comparison of Intermittent Antegrade Cardioplegia and Antegrade/retrograde Cardioplegia in Cardiac Surgery: A Propensity-matched Analysis.</a></strong></p><p>Beyazal OF, Yaz&#305;c&#305; S, Temizt&#252;rk Z, Ayd&#305;n C, Do&#287;an E et al.</p><p>Turk Gogus Kalp Damar Cerrahisi Derg. 2026 Mar 27. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s12871-026-03757-4">Oxygenator-related Gaseous Microemboli and Postoperative Delirium after On-pump Coronary Artery Bypass Grafting: a Prospective Cohort Study.</a></strong></p><p>Tutu&#353; V, Paunovi&#263; M, Kuli&#263; S, Rajovic N, Mili&#263; N et al.</p><p>BMC Anesthesiol. 2026 Mar 26;26(1):281 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1007/s00246-026-04193-4">Quantitative Electroencephalogram Patterns During Neonatal Antegrade Cerebral Perfusion and Deep Hypothermic Circulatory Arrest that Suggest Neurologic Injury.</a></strong></p><p>Orie GA, Swartz MF, Seltzer L, Yoshitake S, Alfieris GM.</p><p>Pediatr Cardiol. 2026 Mar 25. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://journals.lww.com/aacr/abstract/2026/03000/unexpected_cardiac_arrest_after_cardiopulmonary.13.aspx">Unexpected Cardiac Arrest After Cardiopulmonary Bypass Initiation, Likely Due to Cardioplegia Migration: A Case Report.</a></strong></p><p>Yamamoto T, Inaba M, Sugimoto A.</p><p>A A Pract. 2026 Mar 25;20(3):e02172</p><p><strong><a href="https://onlinelibrary.wiley.com/doi/10.1002/pan.70172">Avoidance of Hyperoxemia Versus Routine Hyperoxia During Cardiopulmonary Bypass in Children With Cyanotic Congenital Heart Disease-A Systematic Review and Meta-Analysis.</a></strong></p><p>Fischer J, Arobo A, Almehandi A, Leidens EC, Apostu EB et al.</p><p>Paediatr Anaesth. 2026 Jun;36(6):607-616</p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(26)00204-1/abstract">The Year in Coagulation and Transfusion: Selected Highlights.</a></strong></p><p>Erdoes G, Koster A, Shore-Lesserson L, Vilnits Y, Steiner ME et al.</p><p>J Cardiothorac Vasc Anesth. 2026 Mar 4. Online ahead of print</p><p><strong><a href="https://journals.lww.com/anesthesia-analgesia/abstract/9900/association_between_ionized_calcium_concentrations.1733.aspx">Association Between Ionized Calcium Concentrations During Weaning From Cardiopulmonary Bypass and Postoperative Low Cardiac Output Syndrome: A Retrospective Cohort Study.</a></strong></p><p>Hamai Y, Okada Y, Ito S, Nakamura T, Takei T et al.</p><p>Anesth Analg. 2026 Mar 24. Online ahead of print</p><p><strong><a href="https://journals.sagepub.com/doi/10.1177/02676591261438976">Oxygenator Oxygen Transfer Performance during Cardiopulmonary Bypass of the Sorin&#174; Inspire 6F&#169;.</a></strong></p><p>Riesterer DM, Eisner C, Wojdyla J, Turra J.</p><p>Perfusion. 2026 Mar 24. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://amjcaserep.com/abstract/full/idArt/950336">Therapeutic Plasma Exchange for Uncontrollable Bleeding After Platelet Inhibition with Ticagrelor: A Report of 2 Cases.</a></strong></p><p>Herrmann A, Mai B, Bai Y, Castillo B, Kar B et al.</p><p>Am J Case Rep. 2026 Mar 22;27:e950336 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s13019-026-03895-3">Cardiac Surgery in Chile: Preoperative Risk Characterization and Analytical Outcomes Pre-operative Risk Characterization in Cardiac Surgeries.</a></strong></p><p>Seguel E, Castillo B, Guinez-Molinos S.</p><p>J Cardiothorac Surg. 2026 Mar 26. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://academic.oup.com/ejcts/article-abstract/68/2/ezag093/8472258">Ross(-Konno) Procedure in Neonates and Infants: A Multicentre Experience.</a></strong></p><p>Bueno-Gomez A, Abella RF, Varrica A, Galletti L, P&#233;rez-Caballero R et al.</p><p>Eur J Cardiothorac Surg. 2026 Feb 5;68(2):ezag093</p><p><strong><a href="https://www.ingentaconnect.com/content/wk/aln/2025/00000143/00000004/art00020">Intravenous Dabigatran for Anticoagulation during Cardiopulmonary Bypass in a Sheep Model.</a></strong></p><p>Nadtochiy SM, Stefanos T, Angona RE, Darrow N, Gu Y et al.</p><p>Anesthesiology. 2025 Oct 1;143(4):862-872</p><p><strong><a href="https://www.ingentaconnect.com/content/wk/aln/2025/00000143/00000004/art00022">Perioperative Glucose Pragmatic (PROGRAM) Trial: Standardized Insulin Management in Surgical Patients.</a></strong></p><p>Zapf M, Henson CP, Huang EY, Wanderer JP, Fowler LC et al.</p><p>Anesthesiology. 2025 Oct 1;143(4):883-893</p><p><strong><a href="https://www.annalsthoracicsurgeryshortrep.org/article/S2772-9931(26)00128-2/fulltext">Use of Extracorporeal Membrane Oxygenation for Management of Hemostasis After Complex Cardiac Surgery</a></strong></p><p>Demessie D, Menassa Y, Divya A, Borgi J</p><p>Ann Thor Surg Case Rep 2026 Apr 1. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.annalsthoracicsurgery.org/article/S0003-4975(26)00011-1/abstract">Temporary Mechanical Circulatory Support and Shock Teams in High-Risk Cardiac Surgery: The Strategic Evolution of Protected Cardiac Surgery.</a></strong></p><p>Salazar L, Nersesian G, Meani P, Bari G, Mariani S et al.</p><p>Ann Thorac Surg. 2026 Jan 14. Online ahead of print</p><p><strong><a href="https://www.sciencedirect.com/science/article/pii/S2616420526000034">The Adsorptive Property of HA380 Hemoperfusion in Inflammation Alleviation during Cardiopulmonary Bypass</a></strong></p><p>Liu H, Ge S</p><p>Extracorporeal Life Support 2026, Apr 15. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.frontierspartnerships.org/journals/transplant-international/articles/10.3389/ti.2026.16316/full">Shaping the Future of AI in Organ Transplantation: Position Paper of the European Society for Organ Transplantation.</a></strong></p><p>Kourounis G, Gilbert S, Knight SR, Leal A, Scully JL et al.</p><p>Transpl Int. 2026 Apr 20;39:16316 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://bmjleader.bmj.com/content/early/2026/03/25/leader-2025-001381">Safety Signals and Near Misses: Exposing the Design Failures We Can Prevent.</a></strong></p><p>Clark J, Guttman O, Kok J.</p><p>BMJ Lead. 2026 Mar 25. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.cureus.com/articles/474939-effects-of-hyperbaric-oxygen-therapy-on-myocardial-injury-and-inflammatory-biomarkers-a-systematic-review-with-qualitative-synthesis?utm_campaign=6829611-Cureus%20U&amp;utm_medium=email&amp;%5C_hsenc=p2ANqtz--BuwU5LFElG0iVkSGlu7_tr-RICy8LLroevh22C9Afp8VMmKYfpwGFvC1RpYyw4sGZTJHjBkvA8lfxX2IBeoQTe1vlIw&amp;%5C_hsmi=416198956&amp;utm_content=416198956&amp;utm_source=hs_automation#!/">Effects of Hyperbaric Oxygen Therapy on Myocardial Injury and Inflammatory Biomarkers: A Systematic Review With Qualitative Synthesis.</a></strong></p><p>Almomany M, Rawashdeh Z, Alshyyab MA, Alnabulsi A, Alodat L et al.</p><p>Cureus. 2026 Apr 5;18(4):e106468 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.eurekaselect.com/article/154115">Anaemia: A Scientific Overview on Types and Recent Advancements in the Detection of Anaemia.</a></strong></p><p>Mitta S, Thirumalesh E, Siva Nandu G, Sushmitha M, Adam Mohammed AT et al.</p><p>Cardiovasc Hematol Agents Med Chem. 2026 Mar 26. . Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.sciencedirect.com/science/article/pii/S2957391225000191">Perioperative Multivariate Analysis and Risk Prediction of Acute Kidney Injury after Cardiac Surgery: Based on Dynamic Temperature Changes during Cardiopulmonary Bypass.</a></strong></p><p>Zhang X, Li W, Shi J, Zhou Z, Li Z et al.</p><p>J Anesth Transl Med. 2025 May 26;4(2):55-64 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://academic.oup.com/eurjcn/article-abstract/25/1/18/8586580">The Global Burden of Cardiovascular Disease in Adults.</a></strong></p><p>Victor G, Shishani K, Vellone E, Froelicher ES.</p><p>Eur J Cardiovasc Nurs. 2026 Apr 3;25(1):18-30</p><p><strong><a href="https://www.pnas.org/doi/10.1073/pnas.2535113123">Biomechanical Anticoagulation by Spherical Platelets in Extracorporeal Systems.</a></strong></p><p>Ji R, Li Y, Li J, Chen H.</p><p>Proc Natl Acad Sci U S A. 2026 Apr 7;123(14):e2535113123 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(26)00112-6/fulltext">Delirium after Coronary Artery Bypass Grafting: Where We Are Now and Setting Goals for Where We Could Go Next.</a></strong></p><p>Jonik B, Kiefer JJ, Augoustides JG.</p><p>J Cardiothorac Vasc Anesth. 2026 Jun;40(6):1606-1608</p><p><strong><a href="https://www.sciencedirect.com/science/article/pii/S1053077025012479">Myocardial Protection with Cardioplegia in Cardiac Surgery: Optimizing Where We Are Now and Setting Goals for Where We Could Go Next.</a></strong></p><p>Augoustides JG.</p><p>J Cardiothorac Vasc Anesth. 2026 Apr;40(4):1064-1066</p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(26)00333-2/fulltext">Artificial Intelligence in Perioperative Cardiothoracic and Vascular Practice: The Development and Deployment of Assisted and Autonomous Care Options.</a></strong></p><p>Augoustides JG.</p><p>J Cardiothorac Vasc Anesth. 2026 Apr 15. Online ahead of print</p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(25)01124-3/fulltext">Suspected Malignant Hyperthermia in a Patient Undergoing Cardiac Surgery: Perioperative Challenges and Management.</a></strong></p><p>Bloom J, Alvarado E, Linganna R, Augoustides JG, Ivanova V et al.</p><p>J Cardiothorac Vasc Anesth. 2026 Feb;40(2):751-757.</p><p><strong><a href="https://www.sciencedirect.com/science/article/pii/S2341192926000934">Use of Extracorporeal Membrane Oxygenation with a Cardiotomy Reservoir for Patient Blood Management in Thoracoabdominal Open Surgery: A Single Centre Experience.</a></strong></p><p>Ruano JS, Aparicio C, Gonzalez A, Carballo L, Enrique Mu&#241;oz L, Manzano F.</p><p>Rev Esp Anestesiol Reanim (Engl Ed). 2026 Mar 28. Online ahead of print</p><p><strong><a href="https://journals.sagepub.com/doi/abs/10.1177/02676591261439568">Evolution of Myocardial Protection Strategies: The Rise of del Nido Cardioplegia in Adult Cardiac Surgery.</a></strong></p><p>Bay&#305;c&#305; BB, K&#305;z&#305;lyel F.</p><p>Perfusion. 2026 Mar 26. Online ahead of print</p><p><strong><a href="https://journals.sagepub.com/doi/full/10.1177/02676591261440347">Perioperative Blood Loss in Cardiac Surgery: Validation of Machine Learning-derived Clusters.</a></strong></p><p>Orazymbetov Y, Aitaliyev S, Jaku&#353;ka P, Veikutien&#279; A, Lenkutis T et al.</p><p>Perfusion. 2026 Mar 26. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://journals.sagepub.com/doi/abs/10.1177/02676591261440360">Predicting Acute Kidney Injury after CABG: Identification of Modifiable Intraoperative Risk Factors.</a></strong></p><p>Pierri MD, Galeazzi M, D&#8217;Alessio S, Silvano R, Mali E et al.</p><p>Perfusion. 2026 Mar 28. Online ahead of print</p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(26)00197-7/fulltext">Excessive Anesthetic Depth Is Associated With Increased Rate of Postoperative Delirium After Cardiac Surgery: A Retrospective Analysis of Processed Electroencephalography.</a></strong></p><p>Benson L, Engerstr&#246;m L, Holm J, Kristenson K.</p><p>J Cardiothorac Vasc Anesth. 2026 Mar 2. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://journals.sagepub.com/doi/10.1177/02184923261438205">From Phthalates to Microplastics: Emerging and Unresolved Biocompatibility Risks in Extracorporeal Circulation.</a></strong></p><p>Condello I, Dsouki YE.</p><p>Asian Cardiovasc Thorac Ann. 2026 May;34(4):380-386</p><p><strong><a href="https://www.jacc.org/doi/10.1016/j.jaccas.2025.106414">Percutaneous Mechanical Aspiration Thrombectomy-Assisted Management of Right-Sided Infective Endocarditis During Pregnancy.</a></strong></p><p>Dunn M, Iqbal T, Wang Y, Sharma R.</p><p>JACC Case Rep. 2026 Apr 1;31(13):106414 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://onlinelibrary.wiley.com/doi/10.1002/mrm.70364">Preclinical 1H MRS Study of a Porcine Model Shows Evidence and Mechanisms for Acute Neuronal Injury in Neonatal Cardiopulmonary Bypass (CPB) Surgery.</a></strong></p><p>Omon A, Gu M, Hurd R, Riemer K, Hanley F, Spielman D.</p><p>Magn Reson Med. 2026 Apr 1. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://journals.sagepub.com/doi/10.1177/02184923261432687">Artificial Intelligence in Extracorporeal Technology: Current Applications and Future Directions-A Narrative Review.</a></strong></p><p>Darbari A, Shetty T.</p><p>Asian Cardiovasc Thorac Ann. 2026 May;34(4):368-379</p><p><strong><a href="https://link.springer.com/article/10.1186/s12871-026-03786-z">Quality Management of Comprehensive Blood Conservation Strategies during Cardiopulmonary Bypass in Pediatric Cardiac Surgery.</a></strong></p><p>Wang W, Wang H, Liu J, Jin Y, Liu J.</p><p>BMC Anesthesiol. 2026 Mar 30;26(1):287 <strong>OPEN ACCESS</strong></p><p></p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://lucpuis.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">Tiny Perfusion Letter is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div><p></p>]]></content:encoded></item><item><title><![CDATA[Tiny Perfusion Letter #816]]></title><description><![CDATA[Tiny Perfusion Letter]]></description><link>https://lucpuis.substack.com/p/tiny-perfusion-letter-816</link><guid isPermaLink="false">https://lucpuis.substack.com/p/tiny-perfusion-letter-816</guid><dc:creator><![CDATA[Luc Puis]]></dc:creator><pubDate>Tue, 14 Apr 2026 12:00:57 GMT</pubDate><enclosure url="https://substackcdn.com/image/fetch/$s_!Fa70!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fa2c04eb5-9a38-4ec1-99c4-a1745b246f8e_640x640.png" length="0" type="image/jpeg"/><content:encoded><![CDATA[<h1>Tiny Perfusion Letter</h1><p>Yip yip yip</p><p>Yap yap yap</p><p>Yada yada yada</p><p>Be-bop-baloo-bop</p><p>A-whop-bam-boom</p><p>It doesn&#8217;t always have to be meaningful, it just has to be something</p><p>It&#8217;s what follows now that matters&#8230;</p><p>#enjoyandshare</p><p></p><p class="button-wrapper" data-attrs="{&quot;url&quot;:&quot;https://lucpuis.substack.com/?utm_source=substack&utm_medium=email&utm_content=share&action=share&quot;,&quot;text&quot;:&quot;Share Tiny Perfusion Letter&quot;,&quot;action&quot;:null,&quot;class&quot;:null}" data-component-name="ButtonCreateButton"><a class="button primary" href="/__u/lucpuis.substack.com/?utm_source=substack&amp;utm_medium=email&amp;utm_content=share&amp;action=share"><span>Share Tiny Perfusion Letter</span></a></p><p></p><p><strong><a href="https://journals.sagepub.com/doi/full/10.1177/21501351261418297">The Potent Complement Stimulus of Sanguineous Versus Crystalloid Cardiopulmonary Bypass Prime during Pediatric Cardiac Surgery.</a></strong></p><p>Bierer JD, Stanzel R, Henderson M, Sapp J, Andreou P et al.</p><p>World J Pediatr Congenit Heart Surg. 2026 Mar 14. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://obgyn.onlinelibrary.wiley.com/doi/10.1002/pd.70069">The Sooner, the Better: Neuroprotective Strategies in Fetuses With Congenital Heart Disease.</a></strong></p><p>Nijman M, van der Meijden MEM, Breur JMPJ, Stegeman R, Jansen NJG et al.</p><p>Prenat Diagn. 2026 Mar;46(3):368-381 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://academic.oup.com/cardiovascres/article/122/5/562/8494234">Anticoagulants Beyond Coagulation: a Narrative Review of Cardiovascular Effects.</a></strong></p><p>Aarts A, Ten Cate H, Ten Cate-Hoek AJ.</p><p>Cardiovasc Res. 2026 Mar 26;122(5):562-577 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.frontiersin.org/journals/health-services/articles/10.3389/frhs.2026.1751580/full">Integrating Theory and Practice: the Core Components Guide for Rigorous Quality Improvement Design.</a></strong></p><p>Howard P, Arrieta J, Leruth C, Bones K, Steinfield R et al.</p><p>Front. Health Serv. 6:1751580. <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jtcvsopen.org/article/S2666-2736(26)00139-7/fulltext">Abnormal Bleeding In the Cardiac Operating Room: An Observational Study of Interrater Reliability Between Anesthetists and Surgeons</a></strong></p><p>Sebestyen A, Behouche A, Picard J, Giai J, Leroy C et al.</p><p>JCTVS Open. 2026 March 6. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770%2826%2900289-2/fulltext">Real-Time Individualization of UFH Dosing in Cardiac Procedures: Development and Validation of an Online ACT-Based Target-Controlled Tool</a></strong></p><p>Ollier E, Massacrier F, Zufferey PJ, Sivard B, Azarnoush K et al.</p><p>J Cardiothorac Vasc Anesth. 2026 Apr 3. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1007/s10877-026-01418-y">From Promising Prototypes to &#8220;Instructions for Use&#8221;: Embedding LLMs Safely in Perioperative and Intensive Care.</a></strong></p><p>Bignami EG, Russo M.</p><p>J Clin Monit Comput. 2026 Apr;40(2):301-304 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1007/s10877-026-01422-2">Describing Hemodynamic States: A Plea for Systematic Terminology.</a></strong></p><p>Saugel B, Lakhal K.</p><p>J Clin Monit Comput. 2026 Apr;40(2):305-307 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1007/s10877-025-01399-4">On the Utility of Near-infrared Spectroscopy-derived Measures for Assessing Cerebrovascular Autoregulation: Results from an Observational Cohort Study.</a></strong></p><p>B&#246;gli SY, Smith C, Olakorede I, Placek MM, Bale G, Smielewski P.</p><p>J Clin Monit Comput. 2026 Apr;40(2):333-344 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1007/s10877-025-01345-4">Intraoperative Renal and Cerebral Tissue Oxygen Saturation Measurements to Predict Postoperative Acute Kidney Injury in Pediatric Cardiac Surgery: a Prospective Observational Study.</a></strong></p><p>Massari D, Modestini M, Niezen CK, Yeh L, Zoutman AC et al.</p><p>J Clin Monit Comput. 2026 Apr;40(2):405-416 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jstage.jst.go.jp/article/ejmj/72/1/72_JMJ25-0066-R/_article">Revisiting the Concept of DIC: A Phenotype-guided Framework for Modern Hemostatic Medicine.</a></strong></p><p>Crochemore T, Scarlatescu E.</p><p>Juntendo Med J. 2026 Feb 17;72(1):45-53 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2846209">Sivelestat and Incidence of Acute Respiratory Distress Syndrome After Cardiovascular Surgery: A Randomized Clinical Trial.</a></strong></p><p>Pan T, Xu C, Wang YP, Wang HL, Su WX et al.</p><p>JAMA Netw Open. 2026 Mar 2;9(3):e260390 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.tandfonline.com/doi/10.1080/14796678.2026.2641608">Intra-aortic Balloon Pump Support in Patients Undergoing Durable Left Ventricular Assist Device Implantation: Contemporary Evidence and Practical Considerations.</a></strong></p><p>Antonios J, Jeng JA, Jeng EI.</p><p>Future Cardiol. 2026 Mar;22(3):301-308</p><p><strong><a href="https://www.sciencedirect.com/science/article/pii/S0163725826000537">Innate Immune Responses Following Myocardial Ischemia and Reperfusion: Evidence, Mechanisms, and Translational Challenges.</a></strong></p><p>Zhang S, Du P, Zhang C, Jie W, Shi GP, Guo J.</p><p>Pharmacol Ther. 2026 Mar 14. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(25)01245-5/abstract">Perioperative Transfusion Requirements in Pediatric Patients Receiving Apixaban Prior to Cardiac Surgery With Cardiopulmonary Bypass.</a></strong></p><p>Longacre MM, VanderPlyum CJ, Staffa SJ, DiNardo JA, Brown ML.</p><p>J Cardiothorac Vasc Anesth. 2026 Apr;40(4):1130-1137</p><p><strong><a href="https://bmjopen.bmj.com/content/16/3/e115288.long">PRECISION Study: Impact of Personalised Cardiac Anaesthesia and Cerebral Autoregulation on Neurological Outcomes in Patients Undergoing Cardiac Surgery - Protocol for an International, Multicentre, Prospective Cohort Study.</a></strong></p><p>Gomes NV, Edgar-Whelan H, Beqiri E, Young J, Schindler C et al.</p><p>BMJ Open. 2026 Mar 18;16(3):e115288 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://karger.com/bpu/article/doi/10.1159/000551559/946351/Rhabdomyolysis-associated-Acute-Kidney-Injury-from">Rhabdomyolysis-associated Acute Kidney Injury: From Pathogenic Mechanisms to the Therapeutic Use of Sorbents.</a></strong></p><p>Naso E, Marengo M, Cantaluppi V.</p><p>Blood Purif. 2026 Mar 16:1-17. Online ahead of print</p><p><strong><a href="https://www.annalsthoracicsurgery.org/article/S0003-4975(26)00228-6/abstract">Results of a Preoperative Screening Brain Magnetic Resonance Imaging Protocol in Neonates Undergoing Cardiopulmonary Bypass.</a></strong></p><p>Islam IS, McGetrick ME, Leon RL, Reyes K, Davies RR et al.</p><p>Ann Thorac Surg. 2026 Mar 19. Online ahead of print</p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(26)00183-7/fulltext">Hemolysis and Acute Kidney Injury Following Cardiac Surgery With Cardiopulmonary Bypass in Patients With Preexisting Renal Dysfunction.</a></strong></p><p>Volleman C, Phelp PG, Dubelaar DPC, Tuip-de Boer AM, Hollander RVG et al.</p><p>J Cardiothorac Vasc Anesth. 2026 Feb 25. Online ahead of print</p><p><strong><a href="https://www.minervamedica.it/en/journals/minerva-anestesiologica/article.php">Comparison of Remimazolam and Sevoflurane on Requirement of Inotropes and Vasopressors in Cardiopulmonary Bypass Surgery: a Propensity-score-matched Retrospective Cohort Study.</a></strong></p><p>Takahashi Y, Yoshii R, Amaya F, Sawa T, Ogawa S.</p><p>Minerva Anestesiol. 2026 Mar 20. Online ahead of print</p><p></p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://lucpuis.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">Thanks for reading Tiny Perfusion Letter! Subscribe for free to receive new posts</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div><p></p>]]></content:encoded></item><item><title><![CDATA[Tiny Perfusion Letter #815]]></title><description><![CDATA[Tiny Perfusion Letter]]></description><link>https://lucpuis.substack.com/p/tiny-perfusion-letter-815</link><guid isPermaLink="false">https://lucpuis.substack.com/p/tiny-perfusion-letter-815</guid><dc:creator><![CDATA[Luc Puis]]></dc:creator><pubDate>Tue, 07 Apr 2026 12:04:13 GMT</pubDate><enclosure url="https://substackcdn.com/image/fetch/$s_!Fa70!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fa2c04eb5-9a38-4ec1-99c4-a1745b246f8e_640x640.png" length="0" type="image/jpeg"/><content:encoded><![CDATA[<h1>Tiny Perfusion Letter</h1><blockquote><p>Hurricane Annie ripped the ceiling off a church and killed everyone inside<a href="https://genius.com/14334579/Prince-sign-o-the-times/Hurricane-annie-ripped-the-ceiling-off-a-church-and-killed-everyone-inside-you-turn-on-the-telly-and-every-other-story-is-tellin-you-somebody-died"><br></a>You turn on the telly and every other story is tellin' you somebody died<br>Sister killed her baby 'cause she couldn't afford to feed it<a href="https://genius.com/3028820/Prince-sign-o-the-times/Sister-killed-her-baby-cause-she-couldnt-afford-to-feed-it-and-were-sending-people-to-the-moon"><br></a>And we're sending people to the moon<br>In September, my cousin tried reefer for the very first time<a href="https://genius.com/19644581/Prince-sign-o-the-times/In-september-my-cousin-tried-reefer-for-the-very-first-time-now-hes-doing-horseits-june"><br></a>Now he's doing horse&#8212;it's June<br>Times<br>Time</p></blockquote><p>Still very relevant, by his Purple Highness&#8230;</p><p>#enjoyandshare</p><p class="button-wrapper" data-attrs="{&quot;url&quot;:&quot;https://lucpuis.substack.com/?utm_source=substack&utm_medium=email&utm_content=share&action=share&quot;,&quot;text&quot;:&quot;Share Tiny Perfusion Letter&quot;,&quot;action&quot;:null,&quot;class&quot;:null}" data-component-name="ButtonCreateButton"><a class="button primary" href="/__u/lucpuis.substack.com/?utm_source=substack&amp;utm_medium=email&amp;utm_content=share&amp;action=share"><span>Share Tiny Perfusion Letter</span></a></p><p></p><p><strong><a href="https://www.sciencedirect.com/science/article/pii/S2666668526000157">Intraoperative Sodium Range Affects White Matter Microstructure in Neonatal Congenital Heart Disease.</a></strong></p><p>van der Meijden MEM, van Loon K, Nijman M, Talacua H, Breur JMPJ et al.</p><p>Int J Cardiol Congenit Heart Dis. 2026 Mar 5;24:100666 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://ject.edpsciences.org/articles/ject/full_html/2026/01/ject250023/ject250023.html">Cybersecurity As It Relates to Perfusion.</a></strong></p><p>Lung K.</p><p>J Extra Corpor Technol. 2026 Mar;58(1):3-18 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC12966988/">Markers of Inflammation and Immunological Competence: Assessment In the Early Postoperative Phase of Cardiac Surgery Involving Extracorporeal Circulation.</a></strong></p><p>Muteveli&#263; S, Bajramovi&#263;-Omeragi&#263; L, &#352;ehi&#263; M, Baljevi&#263;-Spahi&#263; S, Pehlivanovi&#263; KB et al.</p><p>J Med Biochem. 2025 Nov 5;44(8):1770-1778 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://ject.edpsciences.org/articles/ject/full_html/2026/01/ject250059/ject250059.html">A Comparative Study of the Effect of Slow and Rapid Initiation of Cardiopulmonary Pump on Tissue Oxygenation Index and Ischemic Complications.</a></strong></p><p>Bagherinasab M, Rezaei S, Moradi AR, Jabbari A, Noori A et al.</p><p>J Extra Corpor Technol. 2026 Mar;58(1):73-78 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://ject.edpsciences.org/articles/ject/full_html/2026/01/ject250054/ject250054.html">Initiating Cardiopulmonary Bypass Using a Dry Venous Line: Implications and Analysis.</a></strong></p><p>Benedict T, Brownlee R, Foley C, Hoyer N, Dell&#8217;Aiera L et al.</p><p>J Extra Corpor Technol. 2026 Mar;58(1):65-72 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://ject.edpsciences.org/articles/ject/full_html/2026/01/ject250061/ject250061.html">Is Continuous In-line Blood Gas Monitoring Reliable during Cardiopulmonary Bypass When PaO2 and PaCO2 Are Calculated Rather Than Measured?</a></strong></p><p>Lee MH, Rosenthal T.</p><p>J Extra Corpor Technol. 2026 Mar;58(1):43-50 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://ject.edpsciences.org/articles/ject/full_html/2026/01/ject250052/ject250052.html">The Effect of Surgical Field Suction Flow Rate and Venous Reservoir Levels on Gaseous Microemboli Transmission&#8902;.</a></strong></p><p>Rath T, Sugden M, Evans E, Dana K, Rentschler M et al.</p><p>J Extra Corpor Technol. 2026 Mar;58(1):19-31 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.mdpi.com/1660-4601/23/2/241">Diversity and Representation in Cardiovascular Research: Evidence Gaps, Emerging Models, and Policy Implications.</a></strong></p><p>Grewal S, Wildish J, Chalmers C, Dedding C, Suurmond J et al.</p><p>Int J Environ Res Public Health. 2026 Feb 14;23(2):241 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://japi.org/article/japi-74-2-52">Profile of Acute Kidney Injury in Patients Undergoing Cardiac Surgery with Use of Cardiopulmonary Bypass Machine.</a></strong></p><p>Ghosh I, Agrahari D, Sangha SS, Behera V, Dogra PM et al.</p><p>J Assoc Physicians India. 2026 Feb;74(2):52-56 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2026.1788870/full">Editorial: Immune Cell Dynamics and Biomarkers in Cardiac Surgery-induced Systemic Inflammatory Response.</a></strong></p><p>Tan J, Ji B, Shao Y, Duan W, Takayama W, Du L.</p><p>Front Cardiovasc Med. 2026 Feb 24;13:1788870 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2846214">Preventing ARDS, Not Treating It-Lessons From Sivelestat After Cardiopulmonary Bypass.</a></strong></p><p>Lee WL, Slutsky AS.</p><p>JAMA Netw Open. 2026 Mar 2;9(3):e261201 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://journals.sagepub.com/doi/10.1177/02676591261433205">Beyond Goal Directed Perfusion: Individualizing O2-delivery to O2-consumption.</a></strong></p><p>Diop S, Mavambu N, Aparicio M, Premachandra A, Th&#232;s J.</p><p>Perfusion. 2026 Mar 1. Online ahead of print</p><p><strong><a href="https://link.springer.com/article/10.1186/s13019-026-03914-3">Pathogenesis of Gaseous Microemboli in Cardiac Surgery. a Comprehensive Overview of Deairing Procedures, Operative Interactions and Risk Factors to Mitigate Postoperative Cerebral Disorders.</a></strong></p><p>Ehrlich T, Juliette P, Klein T, Phamisith E, Hereson L et al.</p><p>J Cardiothorac Surg. 2026 Mar 14. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.pnas.org/doi/10.1073/pnas.2507008123">Elevated Phthalate Exposure and Metabolic Susceptibility Increased Breast Cancer Risk: A 20-y Follow-up Study in Taiwan.</a></strong></p><p>Chen HC, You SL, Lin CH, Sun CW, Chiang CJ et al.</p><p>Proc Natl Acad Sci U S A. 2026 Mar 17;123(11):e2507008123</p><p><strong><a href="https://www.sciencedirect.com/science/article/pii/S1053077025011735">Hyperlipidemia and Postoperative Hallucinations After Cardiac Surgery: Insights from the VAACS Cohort Study.</a></strong></p><p>Abu Khadija H, Abu Hamdeh N, Najajra D, Masu&#8217;d M, Dabash A et al.</p><p>J Cardiothorac Vasc Anesth. 2026 Apr;40(4):1155-1170</p><p><strong><a href="https://www.sciencedirect.com/science/article/pii/S1053077025012364">The Role of Sequential Organ Failure Assessment Scores and Perfusion Markers in Predicting Postoperative Complications After Cardiac Surgery.</a></strong></p><p>Vujovi&#263; B, Giraud R, Mili&#269;i&#263; B, Kalezi&#263; N, Bendjelid K.</p><p>J Cardiothorac Vasc Anesth. 2026 Apr;40(4):1187-1194</p><p><strong><a href="https://www.sciencedirect.com/science/article/pii/S1053077025003283">The Impact of Body Temperature on Neurologic Outcomes in Neonatal Aortic Arch Surgery Using Antegrade Cerebral Perfusion: A Scoping Review.</a></strong></p><p>Treurniet L, Martherus B, Talacua H, Alderliesten T, Schoof P et al.</p><p>J Cardiothorac Vasc Anesth. 2026 Apr;40(4):1266-1275 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.sciencedirect.com/science/article/pii/S1053249825024623">A Paradigm Shift in Donor Heart Preservation - Years In the Making.</a></strong></p><p>Gunn TM, Salerno CT.</p><p>J Heart Lung Transplant. 2026 Apr;45(4):553-554</p><p><strong><a href="https://journals.lww.com/asaiojournal/fulltext/9900/coronary_arteries_investigation_in_normothermic_ex.921.aspx">Coronary Arteries Investigation in Normothermic Ex Situ Heart Perfusion Machine.</a></strong></p><p>Nurmykhametova Z, Kaliyev R, Medressova A, Lesbekov T, Faizov L et al.</p><p>ASAIO J. 2026 Mar 10. Online ahead of print</p><p><strong><a href="https://academic.oup.com/cardiovascres/article/122/2/178/8432336">Impact of Amino Acid Supplementation on Cardiovascular and Chronic Kidney Diseases: a Systematic Review.</a></strong></p><p>Mikolajetz D, Kalim S, Noels H, Wu Z, Jankowski V et al.</p><p>Cardiovasc Res. 2026 Mar 16;122(2):178-194 <strong>OPEN ACCESS</strong></p><p></p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://lucpuis.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">Thanks for reading Tiny Perfusion Letter! Subscribe for free to receive new posts</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div><p></p><p></p>]]></content:encoded></item><item><title><![CDATA[Tiny Perfusion Letter #814]]></title><description><![CDATA[Tiny Perfusion Letter]]></description><link>https://lucpuis.substack.com/p/tiny-perfusion-letter-814</link><guid isPermaLink="false">https://lucpuis.substack.com/p/tiny-perfusion-letter-814</guid><dc:creator><![CDATA[Luc Puis]]></dc:creator><pubDate>Tue, 31 Mar 2026 12:02:00 GMT</pubDate><enclosure url="https://substackcdn.com/image/fetch/$s_!Fa70!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fa2c04eb5-9a38-4ec1-99c4-a1745b246f8e_640x640.png" length="0" type="image/jpeg"/><content:encoded><![CDATA[<h1>Tiny Perfusion Letter</h1><p>We took a little break from TPLing, to attend a conference</p><p>On multiple occasions, people we met there, were very kindly expressing their sympathy for the TPL, and especially appreciated the little piece of text that we&#8217;re writing right now &#128522;</p><p>That feels like a hot-shot to our &#129728; and so we want to give a big shoutout to, well, just all of you!!</p><p>Thank you for being a subscriber and spreading the love!</p><p>#enjoyandshare</p><p></p><p class="button-wrapper" data-attrs="{&quot;url&quot;:&quot;https://lucpuis.substack.com/?utm_source=substack&amp;utm_medium=email&amp;utm_content=share&amp;action=share&quot;,&quot;text&quot;:&quot;Share Tiny Perfusion Letter&quot;,&quot;action&quot;:null,&quot;class&quot;:null}" data-component-name="ButtonCreateButton"><a class="button primary" href="/__u/lucpuis.substack.com/?utm_source=substack&amp;utm_medium=email&amp;utm_content=share&amp;action=share"><span>Share Tiny Perfusion Letter</span></a></p><p></p><p><strong><a href="https://onlinelibrary.wiley.com/doi/10.1111/aas.70214">APECx-Anaesthesia, Perfusion and Surgical Practices in Cardiac Surgery: Main Study Protocol of a Modular Multiphase Prospective International Multicentre Observational Study.</a></strong></p><p>Seegers JC, Grewal N, van Vliet R, Berger T, Bhatia B et al.</p><p>Acta Anaesthesiol Scand. 2026 Apr;70(4):e70214 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1007/s10877-026-01424-0">Regional Tissue Perfusion Index (RTPI): A New Optical-based Metric for Quantifying Regional Tissue Perfusion.</a></strong></p><p>Shadgan B, Amani Tehrani I, Khosravi S, Askari Z, Pirhadi Rad AP, Bashashati A.</p><p>J Clin Monit Comput. 2026 Feb 24. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.ahajournals.org/doi/10.1161/CIRCHEARTFAILURE.125.013750">Arterial Versus Mixed Venous Lactate Levels in 1526 Cardiac Intensive Care Patients.</a></strong></p><p>Vandenbriele C, Galiatsou E, Rosenberg A.</p><p>Circ Heart Fail. 2026 Mar 3. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.sciencedirect.com/science/article/abs/pii/S0952818026000358">Incidence of Phosphate Abnormalities after Cardiac Surgery and Their Association with Lactic Acidosis: A Cohort Study from the Multicenter Perioperative Outcomes Group.</a></strong></p><p>Steck DT, Silliman WL, Li R, O&#8217;Reilly-Shah VN, Mathis M et al.</p><p>J Clin Anesth. 2026 Mar 4. Online ahead of print</p><p><strong><a href="https://cvja.co.za/journal/cvja-2025-055/">The Effect of Cardiopulmonary Bypass on Platelet Distribution Width, Red Cell Distribution Width - Standard Deviation, and Platelet Large Cell Ratio.</a></strong></p><p>Ama&#231; B, Ba&#287;i&#351; MZ.</p><p>Cardiovasc J Afr. 2025 Sep 3;36(3):368-373 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://cvja.co.za/journal/cvja-2025-056/">The Effect of Cardiopulmonary Bypass Prime Solution Volume on Blood Transfusion: How Do Perfusionists Manage Fluid and What Is the Optimal Prime Solution Volume?</a></strong></p><p>Ama&#231; B, Ba&#287;i&#351; MZ, Ersoy M.</p><p>Cardiovasc J Afr. 2025 Sep 3;36(3):374-379 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://cvja.co.za/journal/cvja-2025-059/">Delta Perfusion Rate Predicts the Development of Adverse Outcome in Cardiopulmonary Bypass Patients.</a></strong></p><p>Ama&#231; B, Abanoz M, Engin M.</p><p>Cardiovasc J Afr. 2025 Sep 26;36(3):424-429 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.j-saudi-heart.com/jsha/vol37/iss4/14/">A Prospective Observational Study on Role of Intraoperative Renal &amp; Muscle Oxygen Saturation on Post-operative Serum Creatinine Level in Patients Undergoing Cardiac Surgery on Cardiopulmonary Bypass.</a></strong></p><p>Banerjee B, Das H, Srivastava L, Pramanik S, Majumder D.</p><p>J Saudi Heart Assoc. 2025 Dec 20;37(4):14 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(26)00110-2/fulltext">Evaluating the Impact of a Standardized Protocol for Managing Refractory Vasoplegia After Cardiopulmonary Bypass.</a></strong></p><p>Teletnick A, Suh K, Boisen M, Brown JA, Cabral B et al.</p><p>J Cardiothorac Vasc Anesth. 2026 Feb 6. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.sciencedirect.com/science/article/abs/pii/S2352556826000408">Hypoperfusion and Cardiac Surgery-associated Major Adverse Kidney Events: A Single-center Retrospective Cohort Study.</a></strong></p><p>Jacquet-Lagr&#232;ze M, Larue M, Ruste M, Schweizer R, Chesnel D, Fellahi JL.</p><p>Anaesth Crit Care Pain Med. 2026 Feb 26. Online ahead of print</p><p><strong><a href="https://revistamedica.imss.gob.mx/index.php/revista_medica/article/view/6878">Early Versus Delayed Post-transfusion Hemoglobin and Hematocrit Measurement in Adults: A Narrative Review.</a></strong></p><p>Nu&#241;ez-Martinez FJ.</p><p>Rev Med Inst Mex Seguro Soc. 2026 Mar 3;64(2):e6878 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s12911-026-03358-8">Machine Learning for the Prediction of Acute Kidney Injury Post Cardiac Surgery: A Systematic Review and Meta-analysis.</a></strong></p><p>Aftab RA, Butt ZA, Ibrahim B, Kun LS.</p><p>BMC Med Inform Decis Mak. 2026 Mar 3. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.sciencedirect.com/science/article/pii/S2352492826003363">Nanoconjugated Anticoagulant Coating with Blood Repellency for Extracorporeal Circulation in Cardiothoracic Surgery</a></strong></p><p>Sun Z, Chen W, Ge N, Dai M, Zhang S, Tong W.</p><p>Materials Today. 2026 Mar 6;52:114952 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://academic.oup.com/ejcts/article/68/2/ezag061/8450332">Interdisciplinary and Cross-Sectoral Perioperative Care Model in Cardiac Surgery: ERAS Implementation in the Setting of Minimally Invasive Heart Valve Surgery (INCREASE)-Results of a Randomized Controlled Trial.</a></strong></p><p>Petersen J, Stock S, Brettschneider C, Dolata L, Dumps C et al.</p><p>Eur J Cardiothorac Surg. 2026 Feb 5;68(2):ezag061 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770%2826%2900246-6/fulltext">Adding the Missing Link &#8211; Integration of Anesthesia and Perfusion Variables into Europe&#180;s largest Congenital Cardiac Surgery Outcomes Database &#8211; Methods and First List of Candidate Variables by an ECHSA &#8211; EACTAIC &#8211; EBCP Collaboration</a></strong></p><p>Meier S, Kousi T, Arrigoni SC, Jacobs JP, Vida V et al.</p><p>J Cardiothorac Vasc Anesth. 2026 Mar 17. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jhltopen.org/article/S2950-1334(26)00061-3/fulltext">A Novel Less Invasive Single Port Pulsatile Ventricular Assist Device</a></strong></p><p>Li L, Chen J, Zhuang Z, Topaz S, Kawabori M et al.</p><p>JHLT Open. 2026 Mar 19. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://journals.lww.com/asaiojournal/abstract/9900/acellular_hemoglobin_impairs_cardiomyocyte.914.aspx">Acellular Hemoglobin Impairs Cardiomyocyte Excitation-Contraction Coupling.</a></strong></p><p>Lucas D, Munoz C, Muller CR, Gu X, Wolfe SR et al.</p><p>ASAIO J. 2026 Mar 4. Online ahead of print</p><p><strong><a href="https://ject.edpsciences.org/articles/ject/full_html/2026/01/ject250053/ject250053.html">A Bedside Staffing Model with Perfusionists for Pediatric Extracorporeal Membrane Oxygenation (ECMO) at a High-volume Center.</a></strong></p><p>Nemeh C, Cain-Trivette C, Schmoke N, Varner C, Brewer M et al.</p><p>J Extra Corpor Technol. 2026 Mar;58(1):51-56 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)02278-0/abstract">Sickle Cell Disease.</a></strong></p><p>Colombatti R, Jastaniah W, Makani J, Andemariam B.</p><p>Lancet. 2026 Mar 14;407(10533):1095-1111</p><p><strong><a href="https://ject.edpsciences.org/articles/ject/full_html/2026/01/ject250026/ject250026.html">Use of Plasmapheresis during Cardiopulmonary Bypass in a Pediatric Heart Transplant of a Patient with Failing Fontan Physiology: First Case in Argentina.</a></strong></p><p>Martinez MJ, Berra I, Cornelis J, Costilla J, Zamora F, Delucis PG.</p><p>J Extra Corpor Technol. 2026 Mar;58(1):79-84 <strong>OPEN ACCESS</strong></p><p></p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://lucpuis.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">Tiny Perfusion Letter is a reader-supported publication. To receive new posts and support my work, consider becoming a subscriber.</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div><p></p>]]></content:encoded></item><item><title><![CDATA[Tiny Perfusion Letter #813]]></title><description><![CDATA[Tiny Perfusion Letter]]></description><link>https://lucpuis.substack.com/p/tiny-perfusion-letter-813</link><guid isPermaLink="false">https://lucpuis.substack.com/p/tiny-perfusion-letter-813</guid><dc:creator><![CDATA[Luc Puis]]></dc:creator><pubDate>Tue, 17 Mar 2026 12:03:19 GMT</pubDate><enclosure url="https://substackcdn.com/image/fetch/$s_!Fa70!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fa2c04eb5-9a38-4ec1-99c4-a1745b246f8e_640x640.png" length="0" type="image/jpeg"/><content:encoded><![CDATA[<h1>Tiny Perfusion Letter</h1><p>You can think &amp; say about A.I. what you want, everyone has a right to their opinion</p><p>We found <strong><a href="/__u/substack.com/home/post/p-187213882">this article</a></strong> by David William Silva really refreshing and to-the-point</p><p>Especially this take was a good one:</p><blockquote><p>There is a meme in Brazil that goes:</p><p><em>&#8220;How do you manage to do so much in a single day?&#8221;</em></p><p><em>&#8220;I do everything very poorly.&#8221;</em></p><p>That is AI in one exchange.</p></blockquote><p>#enjoyandshare</p><p></p><p class="button-wrapper" data-attrs="{&quot;url&quot;:&quot;https://lucpuis.substack.com/?utm_source=substack&amp;utm_medium=email&amp;utm_content=share&amp;action=share&quot;,&quot;text&quot;:&quot;Share Tiny Perfusion Letter&quot;,&quot;action&quot;:null,&quot;class&quot;:null}" data-component-name="ButtonCreateButton"><a class="button primary" href="/__u/lucpuis.substack.com/?utm_source=substack&amp;utm_medium=email&amp;utm_content=share&amp;action=share"><span>Share Tiny Perfusion Letter</span></a></p><p></p><p><strong><a href="https://pubmed.ncbi.nlm.nih.gov/41745202/">Lean Body Weight-indexed O<sub>2</sub></a><a href="https://journals.sagepub.com/doi/10.1177/02676591261430630"> Delivery during Cardiopulmonary Bypass and Acute Kidney Injury.</a></strong></p><p>Carter HH, Dauch W, Dooley M, Dell&#8217;Aiera L, Newland R.</p><p>Perfusion. 2026 Feb 26. Online ahead of print</p><p><strong><a href="https://www.pnas.org/doi/10.1073/pnas.2537961123">The Way of Life: The Network Challenge of Blood Flow in the Brain.</a></strong></p><p>Schmid F.</p><p>Proc Natl Acad Sci U S A. 2026 Mar 3;123(9):e2537961123</p><p><strong><a href="https://www.mdpi.com/2308-3425/13/2/81">Clinical Application of Inhaled Nitric Oxide in Conditions of Excessive Right Heart Load: A Review from Neonatal Pulmonary Hypertension to Perioperative Cardiac Surgery Management.</a></strong></p><p>Hu C, Chen Z, Lv L, Zhu Y, Chen Y, Wang Q.</p><p>J Cardiovasc Dev Dis. 2026 Feb 8;13(2):81 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.mdpi.com/2073-4409/15/4/346">Endothelin-1 and Vasomotor Tone Following Cardioplegic Ischemia/Reperfusion and Cardiopulmonary Bypass.</a></strong></p><p>Kant S, Sellke F, Feng J.</p><p>Cells. 2026 Feb 14;15(4):346 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.mdpi.com/1660-4601/23/2/156">Prevalence of Musculoskeletal Disorders Among Perfusion Staff in Germany.</a></strong></p><p>Gre&#223;ler AR, Kehmann M, Backhaus C, Hinricher N.</p><p>Int J Environ Res Public Health. 2026 Jan 27;23(2):156 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s12871-026-03707-0">Benefits of Nitric Oxide Administration during Cardiopulmonary Bypass on Postoperative Outcomes in Adult Patients: a Meta-analysis and Systematic Review.</a></strong></p><p>Zhang Y, Wang M, Chen G, Zhou Y.</p><p>BMC Anesthesiol. 2026 Feb 25. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.sciencedirect.com/science/article/abs/pii/S0169260726000544">Emboli Transport In a Full Patient-specific Aortic Tree: Assessment of Abdominal Organ Injury Risk during Cardiopulmonary Bypass.</a></strong></p><p>Arefin NM, Good BC.</p><p>Comput Methods Programs Biomed. 2026 Feb 16. Online ahead of print</p><p><strong><a href="https://www.cureus.com/articles/452517-stone-heart-syndrome-after-aortic-valve-replacement-for-severe-aortic-stenosis-a-case-report#!/">Stone Heart Syndrome After Aortic Valve Replacement for Severe Aortic Stenosis: A Case Report.</a></strong></p><p>Papageorgiou L.</p><p>Cureus. 2026 Jan 21;18(1):e101968 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.sciencedirect.com/science/article/pii/S0022522325008517">Propofol-supplemented Cardioplegia: A Multicenter Blinded 3-group Randomized Trial (Propofol for Myocardial Protection Trial 2: ProMPT2).</a></strong></p><p>Angelini GD, Smartt HJM, Joyce K, Heys R, Maishman R et al.</p><p>J Thorac Cardiovasc Surg. 2026 Mar;171(3):649-658</p><p><strong><a href="https://www.sciencedirect.com/science/article/abs/pii/S002252232500635X">Optimizing Patient Blood Management through Intraoperative Goal-directed Fluid Therapy Protocol Within an Enhanced Recovery after Cardiac Surgery Program.</a></strong></p><p>Schneider C, Darras M, Oulehri W, Marguerite S, Saad&#233; S. et al.</p><p>J Thorac Cardiovasc Surg. 2026 Mar;171(3):671-680</p><p><strong><a href="https://academic.oup.com/ejcts/article/68/2/ezag064/8475616">Obesity Does Not Influence the Outcomes of Minimally Invasive Mitral Valve Repair for Mitral Regurgitation: A Longitudinal Analysis.</a></strong></p><p>Mazur P, Gadelkarim I, Marin-Cuartas M, Leontyev S, Dashkievich A et al.</p><p>Eur J Cardiothorac Surg. 2026 Feb 5;68(2):ezag064</p><p><strong><a href="https://journals.sagepub.com/doi/full/10.1177/02676591251348804">Clinical Impact of Changes in Plasma Osmolarity and Pump Time during Cardiopulmonary Bypass Use.</a></strong></p><p>Politi MT, Izurieta M, Barba V, Di Benedetto S, Ferreyra R et al.</p><p>Perfusion. 2026 Mar;41(2):187-196</p><p><strong><a href="https://academic.oup.com/icvts/advance-article/doi/10.1093/icvts/ivag059/8508653">Contemporary Clinical Practices in Anticoagulation Management During Cardiopulmonary Bypass: A Europe-Wide Survey.</a></strong></p><p>Pereira RM, Guerra N, Ferreira R, Nobre &#194;, Moita LF, Velho TR.</p><p>Interdiscip Cardiovasc Thorac Surg. 2026 Mar 5:ivag059. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://journals.sagepub.com/doi/full/10.1177/02676591251357431">Hereditary Spherocytosis In a Neonate during Cardiac Surgery.</a></strong></p><p>Richardson R, Crook R.</p><p>Perfusion. 2026 Mar;41(2):225-227</p><p><strong><a href="https://www.pnas.org/doi/10.1073/pnas.2526444123">Aerophilic Debubbling.</a></strong></p><p>Vandereydt BJC, Nath S, Varanasi KK.</p><p>Proc Natl Acad Sci U S A. 2026 Mar 3;123(9):e2526444123 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.nature.com/articles/s41586-025-10091-1">Long-term Thrombus-free Left Atrial Appendage Occlusion via Magnetofluids.</a></strong></p><p>Wang S, Ju W, Zhuang D, Chen Z, Zhao D et al.</p><p>Nature. 2026 Mar;651(8104):91-99 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://journals.sagepub.com/doi/full/10.1177/21501351261418275">Regional Variation in Congenital Heart Surgery in Brazil: A National Database Analysis.</a></strong></p><p>Miana LA, Jacobs JP, Passos JPU, Jatene MB.</p><p>World J Pediatr Congenit Heart Surg. 2026 Feb 27. Online ahead of print</p><p><strong><a href="https://cvja.co.za/journal/cvja-2025-040/">Effects of Mild and Moderate Hypothermia on Renal Injury Evaluated with Neutrophil Gelatinase Associated Lipocalin Cystatin C and Near Infrared Spectroscopy in Patients undergoing Cardiopulmonary Bypass Graft Surgery.</a></strong></p><p>Yildirim S, &#214;&#231; B, &#350;im&#351;ek M, T&#252;lek F, Arun OU, &#214;&#231; M.</p><p>Cardiovasc J Afr. 2025 Sep 3;36(3):280-286 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://journals.sagepub.com/doi/10.1177/02676591261431999">Post-operative Oxygen Delivery and Delirium after Cardiac Surgery with Cardiopulmonary Bypass: A Multisite Retrospective Cohort Study of 1,690 Patients.</a></strong></p><p>Christensen E, Kennerley V, Justison G, Douin DJ, Pattee J et al.</p><p>Perfusion. 2026 Mar 6. Online ahead of print</p><p><strong><a href="https://journals.sagepub.com/doi/10.1177/10760296261432450">A Prospective Analysis of Viscoelastic Assays, Platelet Aggregometry, and Standard Laboratory Tests in Predicting Perioperative Blood Loss in Cardiac Surgery.</a></strong></p><p>Orazymbetov Y, Aitaliyev S, Jaku&#353;ka P, Veikutien&#279; A, Lenkutis T et al.</p><p>Clin Appl Thromb Hemost. 2026 Jan-Dec;32 <strong>OPEN ACCESS</strong></p><p></p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://lucpuis.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">Thanks for reading Tiny Perfusion Letter! Subscribe for free to receive new posts</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div><p></p>]]></content:encoded></item><item><title><![CDATA[Tiny Perfusion Letter #812]]></title><description><![CDATA[Tiny Perfusion Letter]]></description><link>https://lucpuis.substack.com/p/tiny-perfusion-letter-812</link><guid isPermaLink="false">https://lucpuis.substack.com/p/tiny-perfusion-letter-812</guid><dc:creator><![CDATA[Luc Puis]]></dc:creator><pubDate>Tue, 10 Mar 2026 12:03:22 GMT</pubDate><enclosure url="https://substackcdn.com/image/fetch/$s_!Fa70!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fa2c04eb5-9a38-4ec1-99c4-a1745b246f8e_640x640.png" length="0" type="image/jpeg"/><content:encoded><![CDATA[<h1>Tiny Perfusion Letter</h1><p>OU812 is the  eighth studio album by Van Halen, the second with Sammy Hagar instead of David Lee Roth. While it reached number 1 in the USA, Canada and &#8230; Finland (!), the reviews were mixed. Ranging from "a record of clear professionalism or barely discernible inspiration, but not both" to "the curve balls [...] don't always hit the strike zone&#8221; and "cynical corporate rock", we can conclude that it would be more advisable to just listen to their first three albums.</p><p>Or to Beat It, from Michael Jackson, featuring Eddie Van Halen on solo guitar as an introduction&#8230;</p><p>Over to science&#8230;</p><p>#enjoyandshare</p><p></p><p class="button-wrapper" data-attrs="{&quot;url&quot;:&quot;https://lucpuis.substack.com/?utm_source=substack&utm_medium=email&utm_content=share&action=share&quot;,&quot;text&quot;:&quot;Share Tiny Perfusion Letter&quot;,&quot;action&quot;:null,&quot;class&quot;:null}" data-component-name="ButtonCreateButton"><a class="button primary" href="/__u/lucpuis.substack.com/?utm_source=substack&amp;utm_medium=email&amp;utm_content=share&amp;action=share"><span>Share Tiny Perfusion Letter</span></a></p><p></p><p><strong><a href="https://www.sciencedirect.com/science/article/abs/pii/S0003497525007635">Impact of Root Venting on Brain Injury in Minithoracotomy Aortic Valve Replacement: Prospective Evaluation With Preoperative and Postoperative Brain MRI in 252 Patients.</a></strong></p><p>Nishijima S, Nakamura Y, Higuma Y, Niitsuma K, Yasumoto Y et al.</p><p>Ann Thorac Surg. 2026 Mar;121(3):597-604</p><p><strong><a href="https://www.annalsthoracicsurgery.org/article/S0003-4975(26)00083-4/fulltext">High-Exchange Ultrafiltration to Enhance Recovery After Pediatric Cardiac Surgery: The ULTRA Randomized Controlled Trial.</a></strong></p><p>Bierer JD, Stanzel R, Henderson M, Krmpotic K, Andreou P et al.</p><p>Ann Thorac Surg. 2026 Jan 27. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.sciencedirect.com/science/article/pii/S0952818026000152">From Fast Track to Enhanced Recovery after Cardiac Surgery: 15 Years of Experience with the Leipzig Concept in a Specialized Post-anesthesia Care Unit.</a></strong></p><p>Zakhary W, Flo Forner A, Holzhey D, Borger MA, Otto W et al.</p><p>J Clin Anesth. 2026 Feb 4;110:112137. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://journals.sagepub.com/doi/full/10.1177/10760296261425036">Hereditary Antithrombin Deficiency in Pediatric Patients: Pathophysiology, Clinical Features, Diagnosis, and Antithrombin Replacement Therapy.</a></strong></p><p>Rodgers GM, Rodriguez WI.</p><p>Clin Appl Thromb Hemost. 2026 Jan-Dec;32:10760296261425036 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.sciencedirect.com/science/article/pii/S2352556825001808">Capillary Refill Time: Six Rules.</a></strong></p><p>Jacquet-Lagr&#232;ze M, Ruste M, Fellahi JL.</p><p>Anaesth Crit Care Pain Med. 2026 Jan;45(1):101648 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jtcvs.org/article/S0022-5223%2826%2900175-3/fulltext">Oxygen Extraction Trajectories During Cardiopulmonary Bypass Impact Postoperative Outcomes in Coronary Artery Bypass Grafting.</a></strong></p><p>Ahmad A, Williams AM, Trahanas J, Bommareddi S, Wang CC et al.</p><p>J Thorac Cardiovasc Surg. 2026 Feb 26. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://journals.sagepub.com/doi/abs/10.1177/17504589261421004">Efficacy of Intranasal Insulin in Reducing the Incidence of Postoperative Delirium: A Systematic Review and Meta-analysis of Randomised Controlled Trials.</a></strong></p><p>Desai A, Bisht R, Carri&#243;n EMM, Maheshwari V, Misra S et al.</p><p>J Perioper Pract. 2026 Feb 22. Online ahead of print</p><p><strong><a href="https://onlinelibrary.wiley.com/doi/10.1002/wjs.70265">Association Between Intraoperative Hyperlactatemia and Infection After Cardiac Surgery With Cardiopulmonary Bypass: A Multicenter Retrospective Study.</a></strong></p><p>Shi Y, Wang Y, Pan J, Chen C, Xiong X et al.</p><p>World J Surg. 2026 Feb 12. Online ahead of print</p><p><strong><a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC12327505/">Handoff Mnemonics Used in Perioperative Handoff Intervention Studies: A Systematic Review.</a></strong></p><p>Patel SM, Fuller S, Michael MM, O&#8217;Hagan EC, Lazzara EH, Riesenberg LA.</p><p>Anesth Analg. 2025 Sep 1;141(3):468-481 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC12327500/">Interpretation of Viscoelastic Hemostatic Assays in Cardiac Surgery Patients: Importance of Clinical Context.</a></strong></p><p>Noteboom SH, Kho E, Veelo DP, van der Ster BJP, van Haeren MMT et al.</p><p>Anesth Analg. 2025 Sep 1;141(3):588-597 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.sciencedirect.com/science/article/pii/S1875213625004474?">Cost-revenue Analysis of Using a Haemoadsorbent Membrane in Patients Undergoing Coronary Artery Bypass Grafting with Cardiopulmonary Bypass and Ticagrelor.</a></strong></p><p>Mathat B, Compaore Y, David CH, Riche VP, Ryan M et al.</p><p>Arch Cardiovasc Dis. 2026 Feb;119(2):115-122 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://journals.sagepub.com/doi/full/10.1177/02676591261427684">Evaluation of Thromboelastometry (Rotem) - guided and Conventional Hemostasis Management Effectiveness in Neonatal Congenital Cardiac Surgery.</a></strong></p><p>Saglam S, Yucel ED, Ali Kahraman I, Ozalp S, Recep E et al.</p><p>Perfusion. 2026 Feb 21. Online ahead of print</p><p><strong><a href="https://link.springer.com/article/10.1186/s12872-025-05407-y">Postoperative Red Cell Distribution Width to Platelet Ratio is Related to Cardiac Surgery-associated Acute Kidney Injury.</a></strong></p><p>Li ZX, Cui CY, Qian XL, Huang JX, Hu JL et al.</p><p>BMC Cardiovasc Disord. 2026 Feb 23;26(1):178 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.sciencedirect.com/science/article/pii/S1385894725069074">Surface Engineering &#8216;Liquid-like&#8217; Solid Surfaces with Nitric Oxide Releasing Polymers to Combat Biofouling.</a></strong></p><p>Shome A, Pandey R, Martinez I, Crutchfield N, Brisbois EJ, Handa H.</p><p>Chem Eng J. 2025 Sep 15;520:166069 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.amjtransplant.org/article/S1600-6135(26)00100-0/abstract">Simultaneous Quantification of Native Human and Transgenic Porcine Liver Function In a Decedent Model of Extracorporeal Cross-circulation.</a></strong></p><p>Shaked A, McRae MP, Imperial JC, Lanieri L, Sagar A et al.</p><p>Am J Transplant. 2026 Feb 20. Online ahead of print</p><p><strong><a href="https://www.mdpi.com/2079-6374/16/2/80">Smart Clot: An Automated Point-of-Care Flow Assay for Quantitative Whole-Blood Platelet, Fibrin, and Thrombus Kinetics.</a></strong></p><p>Foladore A, Lattanzio S, Baryshnikova E, Anguissola M, Lombardi E et al.</p><p>Biosensors (Basel). 2026 Jan 28;16(2):80 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.bjanaesthesia.org/article/S0007-0912(26)00046-2/abstract">Association of Duration of Amino Acids Infusion and Renal Protection: A Secondary Analysis of the PROTECTION Trial.</a></strong></p><p>Landoni G, Oriani A, Ti LK, Losiggio R, Bradic N et al.</p><p>Br J Anaesth. 2026 Feb 24. Online ahead of print</p><p><strong><a href="https://www.mdpi.com/2077-0383/15/4/1435">The Impact of Cardiopulmonary Bypass on the Structure and Mechanics of Red Blood Cells: Pilot Study.</a></strong></p><p>Sergunova V, Akselrod B, Kandrashina S, Guskov D, Shvedov M et al.</p><p>J Clin Med. 2026 Feb 12;15(4):1435 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.mdpi.com/2075-4418/16/4/515">Preoperative Glycemic Status in Elective Cardiac Surgery Procedures: HbA1c Independently Predicts Low Cardiac Output Syndrome and Mortality.</a></strong></p><p>Ampatzidou F, Kotoulas SC, Papaioannou M, Mouratidou C, Massa E et al.</p><p>Diagnostics (Basel). 2026 Feb 9;16(4):515 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://link.springer.com/article/10.1186/s12872-026-05638-7">Association Between Cardiopulmonary Bypass Weaning Time and Adverse Outcomes in Patients with Aortic Dissection Who Underwent Total Arch Replacement Combined with Stented Elephant Trunk Implantation.</a></strong></p><p>Li P, Zhang S, Zhang C, Jiang N, Bai Y, Chen Q.</p><p>BMC Cardiovasc Disord. 2026 Feb 26. Online ahead of print <strong>OPEN ACCESS</strong></p><p></p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://lucpuis.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">Thanks for reading Tiny Perfusion Letter! Subscribe for free to receive new posts</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div><p></p><p></p><p></p>]]></content:encoded></item><item><title><![CDATA[Tiny Perfusion Letter #811]]></title><description><![CDATA[Tiny Perfusion Letter]]></description><link>https://lucpuis.substack.com/p/tiny-perfusion-letter-811</link><guid isPermaLink="false">https://lucpuis.substack.com/p/tiny-perfusion-letter-811</guid><dc:creator><![CDATA[Luc Puis]]></dc:creator><pubDate>Tue, 03 Mar 2026 13:02:44 GMT</pubDate><enclosure url="https://substackcdn.com/image/fetch/$s_!Fa70!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fa2c04eb5-9a38-4ec1-99c4-a1745b246f8e_640x640.png" length="0" type="image/jpeg"/><content:encoded><![CDATA[<h1>Tiny Perfusion Letter</h1><p>We&#8217;ve heard about dogs &#128054;, rats&#128000;, sheep &#128017;, rabbits &#128048;, horses &#128014;, monkeys &#128018;, hamsters &#128057;, mice &#128045; and even <a href="https://youtu.be/bkm1dHTR8kw?si=6V-okrBjpwZeTbvN">King Kong</a> &#129421;, but actually never heard about a cat &#128008; going on cardiopulmonary bypass</p><p>That&#8217;s the thing about perfusion - if you can imagine it happening, somebody probably already did it somewhere&#8230;</p><p>#enjoyandshare</p><p class="button-wrapper" data-attrs="{&quot;url&quot;:&quot;https://lucpuis.substack.com/?utm_source=substack&utm_medium=email&utm_content=share&action=share&quot;,&quot;text&quot;:&quot;Share Tiny Perfusion Letter&quot;,&quot;action&quot;:null,&quot;class&quot;:null}" data-component-name="ButtonCreateButton"><a class="button primary" href="/__u/lucpuis.substack.com/?utm_source=substack&amp;utm_medium=email&amp;utm_content=share&amp;action=share"><span>Share Tiny Perfusion Letter</span></a></p><p></p><p><strong><a href="https://www.sciencedirect.com/science/article/abs/pii/S1760273426000068">Prevention of Blood Dilution during Cardiopulmonary Bypass Surgery in a Cat with Ventricular Septal Defect.</a></strong></p><p>Kanno N, Suzuki H, Yamada S, Yotsuida H.</p><p>J Vet Cardiol. 2026 Jan 21;65:1-6. doi: 10.1016/j.jvc.2026.01.006. Online ahead of print</p><p><strong><a href="https://journals.sagepub.com/doi/10.1177/02676591261422997">How Does Rewarming Temperature Affect Bleeding after Mitral Valve Repair?</a></strong></p><p>Cheng YH, Han YF, Zeng JW, Ma WG, Sun K et al.</p><p>Perfusion. 2026 Feb 11. Online ahead of print</p><p><strong><a href="https://ieeexplore.ieee.org/document/11346963">Development of an Optical Sensor for Real-Time Monitoring of Hemodynamic Parameters in Extracorporeal Settings.</a></strong></p><p>Elgabori O, Scammon WB, Strong KR, Wu J, Cook KE, Kainerstorfer JM.</p><p>IEEE J Transl Eng Health Med. 2026 Jan 12;14:36-44 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.sciencedirect.com/science/article/abs/pii/S2341192926000466">Systemic Inflammatory Response Syndrome after Cardiopulmonary Bypass: Prevalence, Predictors, and Outcomes.</a></strong></p><p>Nu&#241;o-Pulido JJ, Gopar-Nieto R, Rojas-Velasco G, Manzur-Sandoval D.</p><p>Rev Esp Anestesiol Reanim (Engl Ed). 2026 Feb 7. Online ahead of print</p><p><strong><a href="https://pubs.acs.org/doi/10.1021/acs.jmedchem.5c02439">Advances in Heparin Reversal Agents: Design Strategies, Structural Features, and Pharmacological Insights.</a></strong></p><p>Zhang W, Stewart C, Xiao A, Zhan Y, Wei T et al.</p><p>J Med Chem. 2026 Feb 26;69(4):3656-3692</p><p><strong><a href="https://www.sciencedirect.com/science/article/abs/pii/S1053077025011462">The Effects of Tranexamic Acid on Renal Outcomes in Patients Undergoing Cardiovascular Surgery: A Systematic Review and Meta-Analysis Compliant With Preferred Reporting Items for Systematic Reviews and Meta-Analyses.</a></strong></p><p>Zhang B, He LX, Yao YT.</p><p>J Cardiothorac Vasc Anesth. 2026 Mar;40(3):844-854</p><p><strong><a href="https://www.sciencedirect.com/science/article/pii/S1053077025011085">Evaluating Topical Antifibrinolytics in Cardiac Surgery: A Systematic Review, Meta-Analysis, and Trial Sequential Analysis.</a></strong></p><p>Montoya-Beltran JS, Ramirez-Herrera L, Pinilla JL, Herazo-Cubillos A, Pe&#241;a-Blanco L, Jimenez Ordo&#241;ez AF.</p><p>J Cardiothorac Vasc Anesth. 2026 Mar;40(3):1024-1036</p><p><strong><a href="https://cvja.co.za/journal/cvja-2025-065/">Association of Prognostic Nutritional Index with Poor Outcomes in Coronary Artery Bypass Grafting.</a></strong></p><p>Albeyo&#287;lu &#350;, Sel&#231;uk N, Atambay A.</p><p>Cardiovasc J Afr. 2025 Oct 27;36(4):467-472 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(25)01243-1/abstract#.">Alterations in Total and Unbound Remimazolam Concentrations During Cardiac Surgery Requiring Cardiopulmonary Bypass: A Single-center Observational Study.</a></strong></p><p>Inoue M, Ueshima S, Kakumoto M, Katsura T, Iwashita N et al.</p><p>J Cardiothorac Vasc Anesth. 2025 Dec 26. Online ahead of print</p><p><strong><a href="https://link.springer.com/article/10.1186/s13019-025-03819-7">Circulatory Arrest Time Above 30 min Have Significantly Detrimental Effects on the Outcomes of Type A Aortic Dissection Repair.</a></strong></p><p>Chakraborty A, Ragupathi A, Nithikasem S, Anglin D, Baek SW et al.</p><p>J Cardiothorac Surg. 2026 Feb 17;21(1):93 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(26)00085-6/fulltext">Impact of Endogenous Melatonin Status on Perioperative Oxidative Stress in Pediatric Cardiac Surgery With Cardiopulmonary Bypass.</a></strong></p><p>Ismayilova F, Freudenthal NJ, M&#252;ller N, Jakobs P, Klein AS et al.</p><p>J Cardiothorac Vasc Anesth. 2026 Jan 22. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://mmcts.org/tutorial/2144">Totally Endoscopic Beating-heart Re-redo Tricuspid Valve Repair Using Smartcanula.</a></strong></p><p>Hecker F, Montagner M, Kofler M, Pitts L, Walther T, Holubec T.</p><p>Multimed Man Cardiothorac Surg. 2026 Feb 17;2026 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://journals.sagepub.com/doi/10.1177/0267659126142684">The Lactate Risk Score (LRS): Anticipating Hyperlactatemia during Cardiopulmonary Bypass.</a></strong></p><p>Condello I, Dell&#8217;Aquila M, Gunaydin S, El Dsouki Y.</p><p>Perfusion. 2026 Feb 16. Online ahead of print</p><p><strong><a href="https://app.jove.com/t/69148/inguinal-cannulation-for-establishing-extracorporeal-circulation">Inguinal Cannulation for Establishing Extracorporeal Circulation in Adult Porcine Model.</a></strong></p><p>M&#246;bius A, F&#252;rster J, Baoer L, Guzm&#225;n-Ruvalcaba MJ, Kraft P et al.</p><p>J Vis Exp. 2026 Jan 30;(227)</p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(26)00041-8/abstract">Operating Room Extubation After Cardiac Surgery: A Promising Practice, or a Product of Selection Bias?</a></strong></p><p>Messinger CJ, Hall E, Smith MR, Mueller A, Hou M et al.</p><p>J Cardiothorac Vasc Anesth. 2026 Jan 14. Online ahead of print</p><p><strong><a href="https://www.jcvaonline.com/article/S1053-0770(26)00035-2/fulltext">Evaluation of the Effect of Intravenous Lidocaine on the Systemic Inflammatory Response Associated With Cardiopulmonary Bypass in Valvular and/or Coronary Cardiac Surgery: Protocol for a Double-Blind Randomized Clinical Trial.</a></strong></p><p>Fern&#225;ndez-Mart&#237;nez A, L&#243;pez Picado A, Gonz&#225;lez-Garc&#237;a J, Aguado Sevilla M, Lobato Solores F et al,</p><p>J Cardiothorac Vasc Anesth. 2026 Jan 10. Online ahead of print <strong>OPEN ACCESS</strong></p><p><strong><a href="https://journals.sagepub.com/doi/10.1177/00031348261425181">Utilization of Cardiopulmonary Bypass in Trauma Patients: A Multi-Institutional Study of the American Association for the Surgery of Trauma.</a></strong></p><p>Karamchandani MM, Nahmias J, Alvarez C, Callcut RA, Stadeli KM et al.</p><p>Am Surg. 2026 Feb 14. Online ahead of print</p><p><strong><a href="https://jcpsp.pk/article-detail/pcomparison-of-classical-blood-cardioplegia-and-modified-del-nido-cardioplegia-on-postoperative-serum-lactate-levels-and-extubation-timesorp">Comparison of Classical Blood Cardioplegia and Modified Del Nido Cardioplegia on Postoperative Serum Lactate Levels and Extubation Times.</a></strong></p><p>Tamtekin B, Ersoy GG.</p><p>J Coll Physicians Surg Pak. 2026 Feb;36(2):248-252</p><p><strong><a href="https://onlinelibrary.wiley.com/doi/10.1155/crog/9480876">Adjuvant Autologous Platelet-Rich Plasma Gel for Decreasing Blood Loss in Posterior Placenta Previa: A Case Series and Literature Review.</a></strong></p><p>Duangkum C, Punjaruk W, Kasetthat T, Buraphaka H, Sitsutheechananon J, Thanoorat T.</p><p>Case Rep Obstet Gynecol. 2026 Feb 18;2026:9480876 <strong>OPEN ACCESS</strong></p><p><strong><a href="https://www.sciencedirect.com/science/article/abs/pii/S095281802600022X">Machine Learning-based Prediction of Significant Intraoperative Blood Loss to Guide Risk-adapted Blood Management Decisions in Spinal Surgery.</a></strong></p><p>Xiao C, Wu Y, Zang H, Liao R, Liao C et al.</p><p>J Clin Anesth. 2026 Feb 16. Online ahead of print</p><p></p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://lucpuis.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">Thanks for reading Tiny Perfusion Letter! Subscribe for free to receive new posts</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div><p></p>]]></content:encoded></item></channel></rss>