<script data-pm-proxy="intercept"></script><?xml version="1.0" encoding="UTF-8"?><rss xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:content="http://purl.org/rss/1.0/modules/content/" xmlns:atom="http://www.w3.org/2005/Atom" version="2.0" xmlns:itunes="http://www.itunes.com/dtds/podcast-1.0.dtd" xmlns:googleplay="http://www.google.com/schemas/play-podcasts/1.0"><channel><title><![CDATA[veryvirology]]></title><description><![CDATA[All things COVID, cutting-edge medical research, and the great struggles of our time.]]></description><link>https://veryvirology.substack.com</link><image><url>https://substackcdn.com/image/fetch/$s_!SM24!,w_256,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fbucketeer-e05bbc84-baa3-437e-9518-adb32be77984.s3.amazonaws.com%2Fpublic%2Fimages%2F6aba14f4-629e-445b-8107-bafd660fa5e7_635x635.png</url><title>veryvirology</title><link>https://veryvirology.substack.com</link></image><generator>Substack</generator><lastBuildDate>Fri, 04 Sep 2026 21:50:45 GMT</lastBuildDate><atom:link href="/__u/veryvirology.substack.com/feed" rel="self" type="application/rss+xml"/><copyright><![CDATA[Adam Gaertner]]></copyright><language><![CDATA[en]]></language><webMaster><![CDATA[veryvirology@substack.com]]></webMaster><itunes:owner><itunes:email><![CDATA[veryvirology@substack.com]]></itunes:email><itunes:name><![CDATA[Adam Gaertner]]></itunes:name></itunes:owner><itunes:author><![CDATA[Adam Gaertner]]></itunes:author><googleplay:owner><![CDATA[veryvirology@substack.com]]></googleplay:owner><googleplay:email><![CDATA[veryvirology@substack.com]]></googleplay:email><googleplay:author><![CDATA[Adam Gaertner]]></googleplay:author><itunes:block><![CDATA[Yes]]></itunes:block><item><title><![CDATA[Curing Cancer: Three Years On]]></title><description><![CDATA[Testimonials, history, and a decision.]]></description><link>https://veryvirology.substack.com/p/curing-cancer-three-years-on</link><guid isPermaLink="false">https://veryvirology.substack.com/p/curing-cancer-three-years-on</guid><dc:creator><![CDATA[Adam Gaertner]]></dc:creator><pubDate>Wed, 02 Sep 2026 02:21:11 GMT</pubDate><enclosure url="https://substackcdn.com/image/fetch/$s_!nuLh!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Ffa265738-7ad5-4df4-bd66-2c0fbcf6bf7f_687x459.png" length="0" type="image/jpeg"/><content:encoded><![CDATA[<p>On October 23rd, 2023, having published the <a href="/__u/veryvirology.substack.com/p/curing-the-incurable-cancer">Ivermectin, Fenbendazole, Vit C and sodium bicarbonate protocol</a> earlier that year, I <a href="https://x.com/veryvirology/status/1716521816200724798">predicted</a>, based on the propaganda cycle we all watched around IVM for Covid, that it would take about 18 months for public awareness to get far enough that the MSM would start propagandizing about it.</p><p>I spent the years that followed, alongside and in parallel with Dr. Makis, Dr. Haider, and numerous others working independently, and with numerous <a href="https://x.com/molsjames/status/1724637347474448547?s=20">practitioners</a> pressing it into successful service, making that information known, as far and wide as I was able.</p><p>With your help, I did manage to hit my target, to <a href="https://x.com/veryvirology/status/1719909301677093030?s=20">reach and educate 10,000 people every day</a>, and then - Lo and behold - <em>almost exactly</em> <em>18 months</em> <em>from the date of that post</em> - the propaganda did indeed commence:</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!hFYG!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F5c272976-9fa8-4809-8b21-176db120d0f7_811x910.jpeg" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!hFYG!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F5c272976-9fa8-4809-8b21-176db120d0f7_811x910.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!hFYG!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F5c272976-9fa8-4809-8b21-176db120d0f7_811x910.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!hFYG!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F5c272976-9fa8-4809-8b21-176db120d0f7_811x910.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!hFYG!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F5c272976-9fa8-4809-8b21-176db120d0f7_811x910.jpeg 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!hFYG!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F5c272976-9fa8-4809-8b21-176db120d0f7_811x910.jpeg" width="811" height="910" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/5c272976-9fa8-4809-8b21-176db120d0f7_811x910.jpeg&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:910,&quot;width&quot;:811,&quot;resizeWidth&quot;:null,&quot;bytes&quot;:177819,&quot;alt&quot;:null,&quot;title&quot;:null,&quot;type&quot;:&quot;image/jpeg&quot;,&quot;href&quot;:null,&quot;belowTheFold&quot;:false,&quot;topImage&quot;:true,&quot;internalRedirect&quot;:&quot;https://veryvirology.substack.com/i/213760123?img=https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F490793c7-12b0-4edc-844f-6a4cca246c41_811x913.jpeg&quot;,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="" srcset="/__u/substackcdn.com/image/fetch/$s_!hFYG!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F5c272976-9fa8-4809-8b21-176db120d0f7_811x910.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!hFYG!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F5c272976-9fa8-4809-8b21-176db120d0f7_811x910.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!hFYG!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F5c272976-9fa8-4809-8b21-176db120d0f7_811x910.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!hFYG!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F5c272976-9fa8-4809-8b21-176db120d0f7_811x910.jpeg 1456w" sizes="100vw" fetchpriority="high"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption">Well, well, well.</figcaption></figure></div><p>The intent of the Covid propaganda was to dismiss and bury the real cures as &#8220;misinformation,&#8221; unexamined and waved off without serious consideration. Had they succeeded, the multitude of studies that were eventually produced, proving its efficacy beyond any doubt, would likely not have come to be, and we would not have the bulletproof evidence that we have today. It would, in fact, look a lot like what we&#8217;ve seen, from professional science and academia, on the subject of ivermectin and fenbendazole for cancer treatment: nothing. No controlled human studies, no conclusions, no successes or statistically massaged failures. Just&#8230; nothing, beyond the <a href="/__u/veryvirology.substack.com/p/curing-the-incurable-cancer">extensive mechanistic evidence</a> with which we started.</p><p></p><p>We all took different approaches to making it known. I tried to mirror what we did the first time, that had so thoroughly succeeded. Simply put, to make it known. Putting the science in front of enough professional eyes, bringing it to enough doctors and scientists, that over time, some of them decide to study it, some decide to use it, and so see the results for themselves, and bringing it to enough people in need, encouraging them to bring it to their doctor rather than self-medicating, so that just like before, it would eventually become self-evident and widespread in common use, even despite the fierce, underhanded opposition.</p><p></p><p>What I didn&#8217;t do was seek out, save, or publish every testimonial or successful report that I received. I sought to put the science front and center, to bring it into widespread practice by default, with the hope that in doing so, the institutional confirmation would come; I never put much stock in the evidentiary value of an anecdote, and I never really sought to convince, or to argue, per se; the science should speak for itself. With so, so many successes over time, perhaps that was a mistake.</p><p></p><p>Which brings me to a message I recently received from a reader. I won&#8217;t, of course, name her, but I would like to address it:</p><p></p><div class="captioned-image-container"><figure><a class="image-link image2" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!Gxzy!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F16a7fced-dd59-4ab7-8c26-98cf700f4406_698x233.png" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!Gxzy!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F16a7fced-dd59-4ab7-8c26-98cf700f4406_698x233.png 424w, /__u/substackcdn.com/image/fetch/$s_!Gxzy!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F16a7fced-dd59-4ab7-8c26-98cf700f4406_698x233.png 848w, /__u/substackcdn.com/image/fetch/$s_!Gxzy!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F16a7fced-dd59-4ab7-8c26-98cf700f4406_698x233.png 1272w, /__u/substackcdn.com/image/fetch/$s_!Gxzy!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F16a7fced-dd59-4ab7-8c26-98cf700f4406_698x233.png 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!Gxzy!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F16a7fced-dd59-4ab7-8c26-98cf700f4406_698x233.png" width="698" height="233" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/16a7fced-dd59-4ab7-8c26-98cf700f4406_698x233.png&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:233,&quot;width&quot;:698,&quot;resizeWidth&quot;:null,&quot;bytes&quot;:59418,&quot;alt&quot;:null,&quot;title&quot;:null,&quot;type&quot;:&quot;image/png&quot;,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:&quot;https://veryvirology.substack.com/i/213760123?img=https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F16a7fced-dd59-4ab7-8c26-98cf700f4406_698x233.png&quot;,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="" srcset="/__u/substackcdn.com/image/fetch/$s_!Gxzy!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F16a7fced-dd59-4ab7-8c26-98cf700f4406_698x233.png 424w, /__u/substackcdn.com/image/fetch/$s_!Gxzy!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F16a7fced-dd59-4ab7-8c26-98cf700f4406_698x233.png 848w, /__u/substackcdn.com/image/fetch/$s_!Gxzy!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F16a7fced-dd59-4ab7-8c26-98cf700f4406_698x233.png 1272w, /__u/substackcdn.com/image/fetch/$s_!Gxzy!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F16a7fced-dd59-4ab7-8c26-98cf700f4406_698x233.png 1456w" sizes="100vw" loading="lazy"></picture><div></div></div></a><figcaption class="image-caption">Aug 27th, 2026.</figcaption></figure></div><p></p><p>I have read, responded to, and missed, a lot of messages over the years. When I saw that, I looked, and I found your email, months earlier, unopened. I am sure there are others. Whether it&#8217;s been in the moments we&#8217;ve been inundated, with some post going mega-viral and waking up to a hundred emails, or during some of our most difficult recent times, when even being able to get to my email at all has been a challenge, I would like you to know that I have not intentionally ignored anything or anyone. I certainly wouldn&#8217;t say that I&#8217;ve &#8216;moved on,&#8217; either; we have, by and large, been so busy just trying to survive lately that there has been very little time or wherewithal for anything but making it from one day to the next. It is deeply regrettable, and I intend to remedy it. I have briefly touched on the challenges we have been facing lately in my most recent articles. They are not, at all, exaggerated. We are, and have been moments from disaster for an inordinately and painfully prolonged period of time now.</p><p></p><p>In reflecting on what I have and haven&#8217;t done, I think, that in light of that, I was remiss in failing to spotlight the many successes that have been had with this protocol. However, my wife, being perhaps a little more prescient in that regard, did endeavor to save a few of the messages she happened to see over time. Her records, although quite limited, to your point about &#8220;whether it works or not,&#8221; are the only organized after-the-fact little archive that we preserved. Real, usable data comes from controlled studies; while it was always heartwarming to hear of various peoples&#8217; successes, oftentimes people I had never even met or spoken to, but had nevertheless come across my work, I did not preserve it as data. Selection bias would serve nobody.</p><p></p><p>With that said, with all of my appreciation to my wife <a href="http://x.com/verycosmic">@verycosmic</a> for having saved these, and while it is far, far from a complete catalog of the hundreds that we&#8217;ve seen over the years, I would like to share a few of them. Public messages are, well, public, and not anonymized; private messages will remain so.</p><p></p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!v3ni!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fc6548e21-85df-4514-a1f7-c74c118e07ec_606x653.png" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!v3ni!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fc6548e21-85df-4514-a1f7-c74c118e07ec_606x653.png 424w, /__u/substackcdn.com/image/fetch/$s_!v3ni!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fc6548e21-85df-4514-a1f7-c74c118e07ec_606x653.png 848w, /__u/substackcdn.com/image/fetch/$s_!v3ni!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fc6548e21-85df-4514-a1f7-c74c118e07ec_606x653.png 1272w, /__u/substackcdn.com/image/fetch/$s_!v3ni!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fc6548e21-85df-4514-a1f7-c74c118e07ec_606x653.png 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!v3ni!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fc6548e21-85df-4514-a1f7-c74c118e07ec_606x653.png" width="368" height="396.54125412541254" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/c6548e21-85df-4514-a1f7-c74c118e07ec_606x653.png&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:653,&quot;width&quot;:606,&quot;resizeWidth&quot;:368,&quot;bytes&quot;:346085,&quot;alt&quot;:null,&quot;title&quot;:null,&quot;type&quot;:&quot;image/png&quot;,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:&quot;https://veryvirology.substack.com/i/213760123?img=https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fc6548e21-85df-4514-a1f7-c74c118e07ec_606x653.png&quot;,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="" srcset="/__u/substackcdn.com/image/fetch/$s_!v3ni!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fc6548e21-85df-4514-a1f7-c74c118e07ec_606x653.png 424w, /__u/substackcdn.com/image/fetch/$s_!v3ni!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fc6548e21-85df-4514-a1f7-c74c118e07ec_606x653.png 848w, /__u/substackcdn.com/image/fetch/$s_!v3ni!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fc6548e21-85df-4514-a1f7-c74c118e07ec_606x653.png 1272w, /__u/substackcdn.com/image/fetch/$s_!v3ni!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fc6548e21-85df-4514-a1f7-c74c118e07ec_606x653.png 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a></figure></div><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!zGKs!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F7eda8d19-c2ed-4ef9-b90e-eaae29d31ee0_342x578.png" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!zGKs!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F7eda8d19-c2ed-4ef9-b90e-eaae29d31ee0_342x578.png 424w, /__u/substackcdn.com/image/fetch/$s_!zGKs!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F7eda8d19-c2ed-4ef9-b90e-eaae29d31ee0_342x578.png 848w, /__u/substackcdn.com/image/fetch/$s_!zGKs!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F7eda8d19-c2ed-4ef9-b90e-eaae29d31ee0_342x578.png 1272w, /__u/substackcdn.com/image/fetch/$s_!zGKs!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F7eda8d19-c2ed-4ef9-b90e-eaae29d31ee0_342x578.png 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!zGKs!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F7eda8d19-c2ed-4ef9-b90e-eaae29d31ee0_342x578.png" width="232" height="392.093567251462" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/7eda8d19-c2ed-4ef9-b90e-eaae29d31ee0_342x578.png&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:578,&quot;width&quot;:342,&quot;resizeWidth&quot;:232,&quot;bytes&quot;:166316,&quot;alt&quot;:null,&quot;title&quot;:null,&quot;type&quot;:&quot;image/png&quot;,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:&quot;https://veryvirology.substack.com/i/213760123?img=https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fbd5d6e62-7cd3-4d5e-be00-5e6efeb67038_342x578.png&quot;,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="" srcset="/__u/substackcdn.com/image/fetch/$s_!zGKs!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F7eda8d19-c2ed-4ef9-b90e-eaae29d31ee0_342x578.png 424w, /__u/substackcdn.com/image/fetch/$s_!zGKs!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F7eda8d19-c2ed-4ef9-b90e-eaae29d31ee0_342x578.png 848w, /__u/substackcdn.com/image/fetch/$s_!zGKs!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F7eda8d19-c2ed-4ef9-b90e-eaae29d31ee0_342x578.png 1272w, /__u/substackcdn.com/image/fetch/$s_!zGKs!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F7eda8d19-c2ed-4ef9-b90e-eaae29d31ee0_342x578.png 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption">Before&#8230;</figcaption></figure></div><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!z8xj!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F639625b9-31ad-408f-b3f9-368932f61d22_370x527.png" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!z8xj!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F639625b9-31ad-408f-b3f9-368932f61d22_370x527.png 424w, /__u/substackcdn.com/image/fetch/$s_!z8xj!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F639625b9-31ad-408f-b3f9-368932f61d22_370x527.png 848w, /__u/substackcdn.com/image/fetch/$s_!z8xj!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F639625b9-31ad-408f-b3f9-368932f61d22_370x527.png 1272w, /__u/substackcdn.com/image/fetch/$s_!z8xj!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F639625b9-31ad-408f-b3f9-368932f61d22_370x527.png 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!z8xj!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F639625b9-31ad-408f-b3f9-368932f61d22_370x527.png" width="240" height="341.8378378378378" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/639625b9-31ad-408f-b3f9-368932f61d22_370x527.png&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:527,&quot;width&quot;:370,&quot;resizeWidth&quot;:240,&quot;bytes&quot;:103410,&quot;alt&quot;:null,&quot;title&quot;:null,&quot;type&quot;:&quot;image/png&quot;,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:&quot;https://veryvirology.substack.com/i/213760123?img=https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F46fe9611-bc9e-4dbd-80fb-253bf96923a2_370x527.png&quot;,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="" srcset="/__u/substackcdn.com/image/fetch/$s_!z8xj!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F639625b9-31ad-408f-b3f9-368932f61d22_370x527.png 424w, /__u/substackcdn.com/image/fetch/$s_!z8xj!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F639625b9-31ad-408f-b3f9-368932f61d22_370x527.png 848w, /__u/substackcdn.com/image/fetch/$s_!z8xj!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F639625b9-31ad-408f-b3f9-368932f61d22_370x527.png 1272w, /__u/substackcdn.com/image/fetch/$s_!z8xj!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F639625b9-31ad-408f-b3f9-368932f61d22_370x527.png 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption">&#8230;and after.</figcaption></figure></div><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!PZem!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Ffdb75310-6b1c-4fee-ac58-a19e5a7b63fa_534x373.png" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!PZem!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Ffdb75310-6b1c-4fee-ac58-a19e5a7b63fa_534x373.png 424w, /__u/substackcdn.com/image/fetch/$s_!PZem!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, 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8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a></figure></div><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!6zaI!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F5c7e25ac-fbcd-44b8-8205-23ce375634ba_766x564.png" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!6zaI!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F5c7e25ac-fbcd-44b8-8205-23ce375634ba_766x564.png 424w, /__u/substackcdn.com/image/fetch/$s_!6zaI!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F5c7e25ac-fbcd-44b8-8205-23ce375634ba_766x564.png 848w, /__u/substackcdn.com/image/fetch/$s_!6zaI!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F5c7e25ac-fbcd-44b8-8205-23ce375634ba_766x564.png 1272w, /__u/substackcdn.com/image/fetch/$s_!6zaI!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F5c7e25ac-fbcd-44b8-8205-23ce375634ba_766x564.png 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!6zaI!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F5c7e25ac-fbcd-44b8-8205-23ce375634ba_766x564.png" width="383" height="282" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/5c7e25ac-fbcd-44b8-8205-23ce375634ba_766x564.png&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:564,&quot;width&quot;:766,&quot;resizeWidth&quot;:383,&quot;bytes&quot;:113959,&quot;alt&quot;:null,&quot;title&quot;:null,&quot;type&quot;:&quot;image/png&quot;,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:&quot;https://veryvirology.substack.com/i/213760123?img=https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F5c7e25ac-fbcd-44b8-8205-23ce375634ba_766x564.png&quot;,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="" srcset="/__u/substackcdn.com/image/fetch/$s_!6zaI!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F5c7e25ac-fbcd-44b8-8205-23ce375634ba_766x564.png 424w, /__u/substackcdn.com/image/fetch/$s_!6zaI!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F5c7e25ac-fbcd-44b8-8205-23ce375634ba_766x564.png 848w, /__u/substackcdn.com/image/fetch/$s_!6zaI!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F5c7e25ac-fbcd-44b8-8205-23ce375634ba_766x564.png 1272w, /__u/substackcdn.com/image/fetch/$s_!6zaI!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F5c7e25ac-fbcd-44b8-8205-23ce375634ba_766x564.png 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption">Just a few, among many.</figcaption></figure></div><p>If you are among those that have reached out over time, only to have heard nothing in response, I want to extend my sincerest apologies to you, and invite you to reach out again, and I will try to make myself available to talk with you. It has not been easy lately. I can also make myself available to consult your practitioner.</p><p></p><p>With that said, having lately been almost entirely silent on Twitter/X, due almost as much to our overwhelming struggles of late, as to my abject disgust with the nigh-irreparable state of the system at large, and the almost wholly compromised and controlled state of the discourse and the &#8220;public square,&#8221; your message was moving. It has made me realize that this work is not complete. I mean, I set out to <em>cure cancer.</em> It&#8217;s not over &#8216;til it&#8217;s over, and right now, the needle is not being meaningfully moved in any institutional, broadly accessible way. Florida&#8217;s initiative was promising; as was the HHS order on supporting independent research; but in every case, the <a href="https://x.com/MakisMedicine/status/2088840354690703444?s=20">usual suspects</a> (surprise) stood up to stand in the way, and instead of the eventual plethora of studies that emerged concerning the antiviral action of ivermectin, now we&#8217;re being told all about the world-changing potential of more LNP-mRNA bioweapons instead.</p><p></p><p>That just won&#8217;t do. We have seen so many successes. Dr. Makis, relentless in his advocacy despite the coordinated attacks from all quarters, attacks with which I&#8217;m all too familiar and sympathetic, has documented so many more. Despite the much more insidious, and at least partially successful campaign to sweep it under the rug this time, we do, in fact, have cures for cancer here, far more effective than LNP-mRNA is ever going to be, and we are far, <em>far</em> from done.</p><p></p><p>My Twitter/X has long since been shadowbanned into the ground, but to the extent that my voice still carries, I intend to resume using it in earnest. Whether that results in the studies and the formal, institutionally quantifiable successes that I hoped would have been forthcoming by now, or another wave of propaganda and suppression, or simply reaching one more doctor or patient in need of it, there is more to be done.</p><p></p><p>We already have cures for cancer, and we don&#8217;t need mRNA in the mix causing more of it. Nearly four years after I published that protocol, that much is, and has been clear. The intervening years have given us nothing but confirmation after confirmation. I wish there were a better, uncensored platform, but beyond Substack, Twitter/X is still the public square by default, and I am still just one voice, in an ocean of algorithmic censorship and modernized, <a href="https://x.com/ShadowofEzra/status/2094184022477844647">well-organized controlled opposition</a>. If I am yet to achieve anything, it will only be with your support and, I think, a new approach. Maybe a more concerted and organized data collection effort. I need to think it over; I don&#8217;t yet exactly know what the right approach will be, but there has to be a way.</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!Uy9A!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Faf83037c-cfa6-4f78-9779-d934a32b0498_800x800.jpeg" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!Uy9A!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Faf83037c-cfa6-4f78-9779-d934a32b0498_800x800.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!Uy9A!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Faf83037c-cfa6-4f78-9779-d934a32b0498_800x800.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!Uy9A!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Faf83037c-cfa6-4f78-9779-d934a32b0498_800x800.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!Uy9A!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Faf83037c-cfa6-4f78-9779-d934a32b0498_800x800.jpeg 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!Uy9A!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Faf83037c-cfa6-4f78-9779-d934a32b0498_800x800.jpeg" width="369" height="369" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/af83037c-cfa6-4f78-9779-d934a32b0498_800x800.jpeg&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:800,&quot;width&quot;:800,&quot;resizeWidth&quot;:369,&quot;bytes&quot;:null,&quot;alt&quot;:&quot;39 Best Thomas Edison Quotes (OPPORTUNITY)&quot;,&quot;title&quot;:null,&quot;type&quot;:null,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:null,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="39 Best Thomas Edison Quotes (OPPORTUNITY)" title="39 Best Thomas Edison Quotes (OPPORTUNITY)" srcset="/__u/substackcdn.com/image/fetch/$s_!Uy9A!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Faf83037c-cfa6-4f78-9779-d934a32b0498_800x800.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!Uy9A!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Faf83037c-cfa6-4f78-9779-d934a32b0498_800x800.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!Uy9A!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Faf83037c-cfa6-4f78-9779-d934a32b0498_800x800.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!Uy9A!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Faf83037c-cfa6-4f78-9779-d934a32b0498_800x800.jpeg 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption">Edison gets it.</figcaption></figure></div><p>If you or a loved one have used this, a related or derivative protocol, or one updated and implemented by your practitioner, please share your story, so that I might be able to share it further; and with your support, and perhaps a different strategy this time, we can finally finish what we started so many years ago.</p>]]></content:encoded></item><item><title><![CDATA[Fauci’s Moderna Millions]]></title><description><![CDATA[Right on cue, the Fauci Defense Fund appears.]]></description><link>https://veryvirology.substack.com/p/faucis-moderna-millions</link><guid isPermaLink="false">https://veryvirology.substack.com/p/faucis-moderna-millions</guid><dc:creator><![CDATA[Adam Gaertner]]></dc:creator><pubDate>Mon, 24 Aug 2026 00:05:38 GMT</pubDate><enclosure url="https://substackcdn.com/image/fetch/$s_!hM_J!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F159c3022-ee72-41fc-8fb2-3049b669147f_1024x1282.png" length="0" type="image/jpeg"/><content:encoded><![CDATA[<div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!hM_J!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F159c3022-ee72-41fc-8fb2-3049b669147f_1024x1282.png" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!hM_J!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F159c3022-ee72-41fc-8fb2-3049b669147f_1024x1282.png 424w, /__u/substackcdn.com/image/fetch/$s_!hM_J!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F159c3022-ee72-41fc-8fb2-3049b669147f_1024x1282.png 848w, /__u/substackcdn.com/image/fetch/$s_!hM_J!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F159c3022-ee72-41fc-8fb2-3049b669147f_1024x1282.png 1272w, /__u/substackcdn.com/image/fetch/$s_!hM_J!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F159c3022-ee72-41fc-8fb2-3049b669147f_1024x1282.png 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!hM_J!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F159c3022-ee72-41fc-8fb2-3049b669147f_1024x1282.png" width="359" height="449.451171875" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/159c3022-ee72-41fc-8fb2-3049b669147f_1024x1282.png&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:1282,&quot;width&quot;:1024,&quot;resizeWidth&quot;:359,&quot;bytes&quot;:1385210,&quot;alt&quot;:null,&quot;title&quot;:null,&quot;type&quot;:&quot;image/png&quot;,&quot;href&quot;:null,&quot;belowTheFold&quot;:false,&quot;topImage&quot;:true,&quot;internalRedirect&quot;:&quot;https://veryvirology.substack.com/i/212303398?img=https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F8d75a974-e6fd-4bf5-bb0f-4ddbef3fda39_1024x1536.png&quot;,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="" srcset="/__u/substackcdn.com/image/fetch/$s_!hM_J!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F159c3022-ee72-41fc-8fb2-3049b669147f_1024x1282.png 424w, /__u/substackcdn.com/image/fetch/$s_!hM_J!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F159c3022-ee72-41fc-8fb2-3049b669147f_1024x1282.png 848w, /__u/substackcdn.com/image/fetch/$s_!hM_J!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F159c3022-ee72-41fc-8fb2-3049b669147f_1024x1282.png 1272w, /__u/substackcdn.com/image/fetch/$s_!hM_J!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F159c3022-ee72-41fc-8fb2-3049b669147f_1024x1282.png 1456w" sizes="100vw" fetchpriority="high"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption">Barely even waited for the trades to clear.</figcaption></figure></div><p>Two days ago, I published <a href="/__u/veryvirology.substack.com/p/no-moderna-did-not-just-cure-cancer">this article</a>. If you haven&#8217;t yet read it, you should do so.</p><p>In it, I made a series of more or less speculative conjectures about insider trading, around the enormous Moderna stock rally, on bogus cancer-curing news, connected to Fauci&#8217;s legal defense funding, against the five and counting state investigations that have, at long, long <em>long</em> long last been initiated against him, as well as the contempt of Congress <s>charges</s> referral, and whatever else might happen to be found, as the world pores over the best evidence yet of years of his corruption.</p><p>I had absolutely zero evidence of any of it.</p><p>Two, (2) days later?</p><p><a href="https://x.com/ginamilan_/status/2090953652458414103">The Anthony S. Fauci M.D. Legal Defense Fund has been launched</a> - not last week, not next week, but a mere <em>two days</em> after that happened - and is taking non-deductible, untraceable, and self-certified donations!</p><p>Publishing a public fundraiser that will undoubtedly, slowly but steadily raise millions, mere days after the checks came in, greatly informs the direction that I imagine they are now taking.</p><p>Ordinarily, hard evidence is the foundation of everything. Every discovery, every assertion, every contention stands backed by years of study, related or otherwise; whatever useful piece of information might apply, dug up, analyzed, and fitted to the puzzle to reveal the bigger picture. Here, with so much just completely unknowable right now, and a world of potentially innocent alternate explanations, but a sequence of events so suspicious it&#8217;s all but screaming, I have to work backwards from that usual methodology.</p><p>With your average vaccinator gazing upon mRNA, <a href="https://x.com/afshineemrani/status/2091190333338185913">stars in their eyes</a> like it&#8217;s the Second Coming, let us instead, for a moment, step into the shoes of this small group of people that have, for the last fifty years, stood wholly above the law, done as they pleased, lied as they saw fit, and as the consequences of their actions have finally started to catch up, pleaded the Fifth one hundred and eleven times.</p><p></p><h2>The Anatomy of a Smurfing Operation</h2><p>Insider trading is a tricky beast. Even with the SEC having been gutted by this administration, and barely a peep to be heard from enforcement these days, you can&#8217;t just run to your broker with inside information and pocket the cash tomorrow. Who do you think you are, Pelosi?</p><p>No. This after-the-fact fundraising push makes a lot of sense now.</p><p>When you need to launder millions in ill-gotten gains, you need <a href="https://financialcrimeacademy.org/smurfing-money-laundering/">smurfs</a>, and you need a lot of them. I mean, you could just open an all-cash car wash, but that&#8217;s a tired old workhorse that&#8217;s gonna take far too long, and I don&#8217;t think anyone would believe that Fauci suddenly decided to take up in the auto cleaning business.</p><p>I&#8217;ve seen this kind of thing play out. If you&#8217;ve ever paid attention to the nuts and bolts of Democratic politics, so have you. Here&#8217;s how it works, and here&#8217;s how we just might be able to catch him this time.</p><p></p><h3>ActBlue</h3><p>ActBlue <a href="https://cha.house.gov/actblue-investigation-timeline">did it best</a>. As the primary payment processing platform for Democratic candidates, causes, and the DNC, ActBlue handled untold millions of donations, both small and large. The vast majority are made by credit card. You enter your name, card, billing address, et cetera, and send them $5 to support your favorite commie. They receive your $5, with many thanks, do <a href="https://www.reddit.com/r/Anarcho_Capitalism/comments/4ulgvw/bernout/">whatever</a> they <a href="https://x.com/conspiracymill/status/1339323715406811137/photo/1">like</a> with it, and store your details for later.</p><p>A few weeks later, Soros throws his hat in the ring with 30 million dollars. But, that&#8217;s above the cap, you say. A single person is only permitted to donate up to $3,500 per candidate per election cycle. How is 30 million dollars, from one man, supposed to make it to Kamala Harris&#8217; bloated campaign coffers?</p><p>Well, it&#8217;s easy. See, that credit card form you filled out, it doesn&#8217;t <em>really</em> care whose money it is, if they don&#8217;t want it to. That $5 donation is peanuts against the personal details they were given in that form. With that data, now they know that John Smith, of 123 Home Street in Ohio, is a guy that likes to send money to Democrats, and he&#8217;s only used about 1% of his legal donation limit so far. Do you think, that if John Smith was a millionaire, he would have given more? Why, of course he would.</p><p>So, he does.</p><p>Unbeknownst to John Smith, his $5 donation has now become a regular $100 donation. Big Data knows just how much he&#8217;s likely to ever donate across an election cycle; stay below that limit, smurf in that Soros money with untraceable prepaid gift cards, and Johnny Moneybags Smith just became your biggest sponsor.</p><p>Repeat that process several million times, and you&#8217;ve got an enormous, ill-gotten, freshly starched and laundered war chest.</p><p>Of course, political donations are public record. So, imagine John Smith&#8217;s surprise when somebody <a href="https://okeefemediagroup.com/breaking-donors-across-the-u-s-deny-massive-actblue-donations-amid-attorney-general-investigations/">actually went to ask him</a> if he really had donated that much! Of course he hadn&#8217;t. But the checks still cleared. The publicly reported nature of political donations is a wrinkle that Fauci, with the best lawyers that millions of aborted babies can buy, won&#8217;t have to deal with here, and one layer of obscurity I do doubt we&#8217;ll yet be able to pierce. Clearing that bar will take a subpoena from one of the states that are investigating, and getting a subpoena requires at least <em>some</em> evidence.</p><p></p><h4>The Media Blitz</h4><p>Of course, that&#8217;s only one half of a two-part operation. For any of this to matter, you still have to manipulate the stock such that the big payday actually arrives. That&#8217;s a whole &#8216;nother can of worms. A favorable article in the Washington Post used to go for around $8000, if memory serves; who knows what a few viral tweets from a few finance guys costs these days, but it&#8217;s probably not that much. Moderna can&#8217;t claim that they just cured cancer, but a random guy on Twitter, with no ostensible connection whatsoever? Free speech, baby. If <a href="https://x.com/wuooods/status/1252051656344317953">Firstname Bunchofnumbers</a> says that Moderna just cured cancer, and fifty thousand Indian bot accounts send it to the viral stratosphere, then as far as the trading algorithms are concerned, Moderna did, in fact, just cure cancer, and suddenly, for no reason at all, 44 billion dollars just appears from thin air.</p><p></p><p>You need an <a href="https://www.washingtonpost.com/news/post-politics/wp/2016/07/25/dnc-staffers-disparaged-top-party-fundraiser-and-wasserman-schultz-ally/">experienced</a> <a href="https://www.youtube.com/watch?v=n4HhDZZvYGk">hand</a> to pull that off. I wonder whose hand it might have been.</p><p></p><h4>As Time Goes On</h4><p>Who, exactly, might have the Moderna Millions right now? Without a subpoena, that&#8217;s something I don&#8217;t think that we can yet know. But it won&#8217;t be Fauci, or his fund, at least for a while yet. A key part of a straw donor smurfing scheme is that <em>you need legitimate donors.</em> They could just buy a database of Americans&#8217; names and details from <a href="https://www.justice.gov/usao-mdfl/pr/ssndob-marketplace-series-websites-listed-more-20-million-social-security-numbers-sale"><s>dark web criminals</s></a> <a href="https://x.com/Hannibal9972485/status/2091047462739796003?s=20"><s>Flock</s></a> <a href="https://www.gao.gov/assets/700/694098.pdf"><s>China</s></a> <a href="https://www.ftc.gov/news-events/news/press-releases/2023/05/ftc-doj-charge-amazon-violating-childrens-privacy-law-keeping-kids-alexa-voice-recordings-forever"><s>Amazon</s></a> <a href="https://x.com/troyhunt/status/1823430024353210700"><s>This guy</s></a> <em><strong>is there anyone that </strong></em><strong>doesn&#8217;t</strong><em><strong> have every American&#8217;s private information at this point?</strong></em> But, at the amounts they&#8217;re likely to be handling, to completely invent them would likely and rapidly fall afoul of AML and KYC law. Once you do have a legitimate donor, nobody&#8217;s really watching to see if they sent you $100 or $1,000, and more importantly, if they&#8217;re actually the ones sending you anything further at all.</p><div class="captioned-image-container"><figure><a class="image-link image2" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!5xrl!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fdbdb3bd8-a0c5-4b08-8c83-4942236824c3_870x168.png" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!5xrl!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fdbdb3bd8-a0c5-4b08-8c83-4942236824c3_870x168.png 424w, /__u/substackcdn.com/image/fetch/$s_!5xrl!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fdbdb3bd8-a0c5-4b08-8c83-4942236824c3_870x168.png 848w, /__u/substackcdn.com/image/fetch/$s_!5xrl!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fdbdb3bd8-a0c5-4b08-8c83-4942236824c3_870x168.png 1272w, /__u/substackcdn.com/image/fetch/$s_!5xrl!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fdbdb3bd8-a0c5-4b08-8c83-4942236824c3_870x168.png 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!5xrl!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fdbdb3bd8-a0c5-4b08-8c83-4942236824c3_870x168.png" width="870" height="168" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/dbdb3bd8-a0c5-4b08-8c83-4942236824c3_870x168.png&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:168,&quot;width&quot;:870,&quot;resizeWidth&quot;:null,&quot;bytes&quot;:33624,&quot;alt&quot;:null,&quot;title&quot;:null,&quot;type&quot;:&quot;image/png&quot;,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:&quot;https://veryvirology.substack.com/i/212303398?img=https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fdbdb3bd8-a0c5-4b08-8c83-4942236824c3_870x168.png&quot;,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="" srcset="/__u/substackcdn.com/image/fetch/$s_!5xrl!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fdbdb3bd8-a0c5-4b08-8c83-4942236824c3_870x168.png 424w, /__u/substackcdn.com/image/fetch/$s_!5xrl!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fdbdb3bd8-a0c5-4b08-8c83-4942236824c3_870x168.png 848w, /__u/substackcdn.com/image/fetch/$s_!5xrl!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fdbdb3bd8-a0c5-4b08-8c83-4942236824c3_870x168.png 1272w, /__u/substackcdn.com/image/fetch/$s_!5xrl!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fdbdb3bd8-a0c5-4b08-8c83-4942236824c3_870x168.png 1456w" sizes="100vw" loading="lazy"></picture><div></div></div></a><figcaption class="image-caption"><em>Donors are responsible for verifying that they own their payment method. Perfectly normal. <a href="https://www.faucilegaldefense.com/">Fauci Fund</a></em></figcaption></figure></div><p>Verifying a donor&#8217;s identity is a walk in the park. Just about everything has some overbearing identity verification built into it these days. Why wouldn&#8217;t they want to know who&#8217;s coming to save Saint Fauci from the big bad Republican witch hunt? In an otherwise particularly laconic TOS, why does that make the cut?</p><p>Because they&#8217;re gonna be citing that one. They have the money. All they need now is a few real people to throw a few dollars at him, the haystack in which to hide their needles, and the Moderna Millions will handle the rest. Mark my words - if and when those records are examined, hundreds or thousands of little $5 and $10 donations will have multiplied, from mountains of sketchy prepaid cards, likely facilitated through a <a href="https://www.foxnews.com/politics/southern-poverty-law-centers-money-woman-allegedly-used-major-bank-fund-pay-to-hate-operation">sympathetic financial institution or two with enough political pull to stay under the radar</a>, even as it hits the fan. Who knows? Do you know? No sir. Not I.</p><p></p><h3>But I&#8217;d like to know.</h3><p>And I&#8217;m guessing you would too.</p><p></p><p>I think it is knowable. The expertise to pull off a campaign like this does not grow on trees. The journalists, the phone calls, the meetings, the accounts; this is the kind of stuff you <a href="https://oversight.house.gov/wp-content/uploads/2023/10/2023.10.05-BRW-Letter-to-HHS-Re.-Morens-Use-of-Personal-Email.pdf">keep off the email record</a> and take care of at the local 10th story whiskey lounge. Actually capturing the stock move, without setting off obvious red flags, will have required either a number of small brokerage accounts, or some backroom <a href="https://www.investor.gov/introduction-investing/investing-basics/glossary/dark-pools">dark pool</a> investment bank <a href="https://www.youtube.com/watch?v=Cxjdj5_5yNM">deals</a>; you need friendly industry insiders for that. Planting an article at CNN? You need a contact for that; while the <a href="https://x.com/RVAwonk/status/2061120767878721546">White</a> <a href="https://www.axios.com/2025/02/27/trump-white-house-conservative-influencers">House</a>, <a href="https://www.nytimes.com/2020/06/15/technology/coronavirus-disinformation-russia-iowa-caucus.html">CIA</a>, <a href="https://x.com/mtaibbi/status/1603857534737072128">FBI</a> and the <a href="https://x.com/DataRepublican/status/1961514843418366438">State Department</a> regularly engage in these kinds of messaging campaigns, albeit only recently having expanded into <a href="https://www.axios.com/2026/03/25/trump-iran-oil-insider-trading">blatant</a> <a href="https://www.cnbc.com/2026/08/07/trump-iran-hormuz-deal-stocks-oil.html">market</a> <a href="https://abc3340.com/news/nation-world/feds-probe-oil-futures-trades-ahead-of-trump-iran-strait-of-hormuz-announcements-prices-trading-activity-report">manipulation</a>, and are <em>generally</em> good enough to <em>generally</em> cover their tracks, this will have been planned for a while, and with the right people, the right data, and time enough to scour every breadcrumb they might not have managed to cover, I think we just might be able to nail that little goblin to the wall on this one.</p><p></p><h4>How?</h4><p>As of right now, I remain completely dispossessed of the remotest shred of evidence of this. I have circumstance, inference, opinion, and a spidey sense that was just, apparently, validated, in the most blatant way I could have possibly imagined. To go from here to there, some hard evidence is going to be required.</p><p></p><p>If - <em>if</em> - this happened, proving it is going to take time, money, and an investigative arc that would make James O&#8217;Keefe proud. Five or six years ago, this kind of sprawling investigation would have taken thousands of hours of manpower, maybe jumping a few flights, making a lot of calls, scouring hundreds of social media profiles and corporate press releases, maybe a FOIA or three, maybe cultivating a few inside sources, and maybe, six long months and a bit of luck later, coming out with an elaborate conspiracy pinboard that nobody would end up acting on anyway.</p><p></p><p>With the modern surveillance state in full swing - and you don&#8217;t need to be the NSA to make completely legitimate use of it, you&#8217;d be surprised what&#8217;s just out there - I think, that with the right data, the right people, a nicely organized pinboard, and a bit of luck yet, it just might be doable. There&#8217;s only a few people in the world that have pulled off this kind of a campaign, and most of them have been on the DNC&#8217;s payroll at some time or another. Fauci, being both a lifelong Democrat and a Rothschild gofer, is well embedded in those circles. Put two and two in a room together, figure out which dots have been having drinks together, and now we&#8217;re cooking with gas.</p><p></p><p>This is all, still, pure speculation. It could go absolutely nowhere. It could be a complete coincidence that, a month after he thumbed his nose at Congress, weeks after Rand Paul printed up his referral and paraded it over to DOJ, weeks after DOJ actually &#8220;received&#8221; it, and weeks after five state attorneys general announced their long-belated investigations, Fauci&#8217;s lawyers only <em>now</em> decided to launch the effort to crowdfund his defense, after Moderna jumped 177% in a single day. Maybe it means nothing at all, and everything was fine in Fauci-land until now. Maybe nothing changed this week.</p><p></p><p>Maybe.</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!e1Vo!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F1a144e4f-eb55-4d72-a08a-d58bae10eb1d_1024x692.jpeg" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!e1Vo!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F1a144e4f-eb55-4d72-a08a-d58bae10eb1d_1024x692.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!e1Vo!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F1a144e4f-eb55-4d72-a08a-d58bae10eb1d_1024x692.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!e1Vo!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F1a144e4f-eb55-4d72-a08a-d58bae10eb1d_1024x692.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!e1Vo!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F1a144e4f-eb55-4d72-a08a-d58bae10eb1d_1024x692.jpeg 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!e1Vo!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F1a144e4f-eb55-4d72-a08a-d58bae10eb1d_1024x692.jpeg" width="609" height="411.55078125" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/1a144e4f-eb55-4d72-a08a-d58bae10eb1d_1024x692.jpeg&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:692,&quot;width&quot;:1024,&quot;resizeWidth&quot;:609,&quot;bytes&quot;:null,&quot;alt&quot;:&quot;Christine Grady&quot;,&quot;title&quot;:null,&quot;type&quot;:null,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:null,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="Christine Grady" title="Christine Grady" srcset="/__u/substackcdn.com/image/fetch/$s_!e1Vo!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F1a144e4f-eb55-4d72-a08a-d58bae10eb1d_1024x692.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!e1Vo!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F1a144e4f-eb55-4d72-a08a-d58bae10eb1d_1024x692.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!e1Vo!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F1a144e4f-eb55-4d72-a08a-d58bae10eb1d_1024x692.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!e1Vo!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F1a144e4f-eb55-4d72-a08a-d58bae10eb1d_1024x692.jpeg 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption"><a href="https://nypost.com/2026/08/06/us-news/faucis-fed-up-wife-flips-the-bird-as-ex-top-doc-miserably-takes-out-trash-hours-after-contempt-vote/">NY Post</a></figcaption></figure></div><p>But I don&#8217;t think so.</p><p></p><p>If you don&#8217;t think so either, and you&#8217;ve got some time to kill, we could put together a working task force group for this. The data is there, but it isn&#8217;t cheap; there will be a decade of contacts, lists, photos, posts and PRs, and eventually that data if we get it, to go through and correlate, and while modern AIs and agents might be able to greatly accelerate, expand, and whittle that search, they can&#8217;t do everything, or exercise much in the way of judgment; and if you read the entirety of my last article, you&#8217;ll know that our circumstances of late have not been particularly conducive to deep research, to put it mildly. Having not discovered any new cures lately, and with a compounding series of disasters that have left us barely possessed of a single computer between us, we have mostly been spending our days just trying to make it to the next. With years of appeals to POTUS and the numerous state AGs, endless Senate hearings and meetings public and private, MAL, media, organizing, publishing, and dedicating every waking minute to this fight, almost all heretofore having fallen on deaf or dumb ears, it had started to seem a little hopeless, but there just might be something further here. Insider trading pales against fifty years of crimes against humanity, but as they say, any port in a storm.</p><p></p><p>Whether we&#8217;re actually able to do anything with it, or not, will be almost entirely up to you. If you&#8217;d like to help, if you&#8217;d like to get that data, or if you&#8217;d just like to be in the room, subscribe, drop a message, or reply to this email, and it&#8217;ll come straight to me. If we can bring a few people together for this, maybe we can get the ball rolling, and maybe that contempt won&#8217;t be the only thread they have to pull.</p><p></p><p>Rarely does it happen to see a signal like that.</p><p></p><p><em>They don&#8217;t let me see who you were, but thank you for the chainsaw and the water distiller from our <a href="https://www.amazon.com/hz/wishlist/ls/26FWZ5WRWDM62?type=wishlist&amp;filter=all&amp;sort=date-added&amp;viewType=list">survival list</a>, and thank you QQ! With things as tight as they&#8217;ve been, it does make a huge difference to us. Winter out here is no slouch, and wood heating is pretty much all we have to stay warm throughout. That is two very heavy weights off our minds.</em></p><p><em>Watching them laundering millions while we&#8217;re barely keeping up with groceries is more than a little galling. We deeply appreciate your support. If you have the means, please consider subscribing or <a href="https://donate.stripe.com/7sIbKx31W6cM3ny7sw">donating</a> to keep us in the fight. We can&#8217;t do any of it without you, and that has never been more evident than these past few difficult months.</em></p><p><em>Thank you for staying with us over the years. It makes all the difference. </em>&#129303;</p><p></p><div><hr></div><p></p><p></p>]]></content:encoded></item><item><title><![CDATA[No, Moderna did not just cure cancer]]></title><description><![CDATA[Fauci&#8217;s legal fees are probably covered, though.]]></description><link>https://veryvirology.substack.com/p/no-moderna-did-not-just-cure-cancer</link><guid isPermaLink="false">https://veryvirology.substack.com/p/no-moderna-did-not-just-cure-cancer</guid><dc:creator><![CDATA[Adam Gaertner]]></dc:creator><pubDate>Fri, 21 Aug 2026 05:40:43 GMT</pubDate><enclosure url="https://substackcdn.com/image/fetch/$s_!H_Mf!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fdacf8a1a-9c4b-4d9c-ad1c-54f426e1ca62_1122x892.png" length="0" type="image/jpeg"/><content:encoded><![CDATA[<p>UPDATE: And two days later, <a href="https://x.com/ginamilan_/status/2090953652458414103">the Anthony S. Fauci Legal Defense fund is launched.</a></p><p></p><div><hr></div><p></p><p>On the same day that Stripe announced <a href="https://www.businessinsider.com/stripe-says-the-singularity-is-here-what-they-told-investors-2026-8">we&#8217;re officially in the Singularity</a>, Moderna, <a href="/__u/www.google.com/search?q=moderna+stock&amp;oq=moderna+stock">NASDAQ:MRNA</a>, just skyrocketed, on the <a href="https://www.cnn.com/2026/08/19/health/moderna-merck-mrna-melanoma-vaccine">news</a> that they &#8230; cured cancer?... After <em>giving</em> cancer to a solid half a percent of the people forced to take their mRNA Covid shots - with around 1.5 million excess cancer cases, since the shots were forced into around 262 million arms, you do the math - they have, to hear the headlines tell it, now gone and cured it.</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!H_Mf!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fdacf8a1a-9c4b-4d9c-ad1c-54f426e1ca62_1122x892.png" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!H_Mf!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, 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/__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fdacf8a1a-9c4b-4d9c-ad1c-54f426e1ca62_1122x892.png 424w, /__u/substackcdn.com/image/fetch/$s_!H_Mf!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fdacf8a1a-9c4b-4d9c-ad1c-54f426e1ca62_1122x892.png 848w, /__u/substackcdn.com/image/fetch/$s_!H_Mf!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fdacf8a1a-9c4b-4d9c-ad1c-54f426e1ca62_1122x892.png 1272w, /__u/substackcdn.com/image/fetch/$s_!H_Mf!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fdacf8a1a-9c4b-4d9c-ad1c-54f426e1ca62_1122x892.png 1456w" sizes="100vw" fetchpriority="high"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption">The more things change&#8230;</figcaption></figure></div><p>They didn&#8217;t cure cancer.</p><p>Really, they didn&#8217;t even directly claim that they&#8217;d cured cancer. That was left to the media and the <a href="https://x.com/bubbleboi/status/2090125989485703595">social</a> <a href="https://x.com/kimmonismus/status/2090082088087150979?s=20">media</a> <a href="https://x.com/typesfast/status/2090241634487480544?s=20">hype</a> <a href="https://x.com/mattturck/status/2090070949567574151?s=20">guys</a> that the market algorithms watch these days. What they did announce was a Phase 3 trial result, of a personalized melanoma &#8220;vaccine,&#8221; that <a href="https://clinicaltrials.gov/study/NCT05933577">met the endpoints they had defined</a>: after surgical resection (ie. the physical cutting away of a tumor) of stage IIB&#8211;IV melanomas, and in combination with pembrolizumab, some percent of 1137 trial participants have survived, for now, without a new relapse. Note that this is a cohort for which <a href="https://seer.cancer.gov/statfacts/html/melan.html">six-year survival is already 94.7%</a>. They haven&#8217;t even released their actual numbers yet, just their &#8216;success&#8217;; if it&#8217;s anything less than 95% survival, only 3 years in, you can guarantee <s>it&#8217;s safe and effective</s> they&#8217;ll be locking us out of grocery stores until we all take it again, and The Science will yet again be pleading the fifth in a few years&#8217; time.</p><p>Melanomas, caught in time - the only kind eligible for enrollment in this trial, given that their tumors had already been resected, of course - are amongst the very, singularly easiest cancers to treat, with about the best prognosis one can possibly hope for with a cancer diagnosis. Caught too late, they are indeed quite deadly and progress very rapidly; but that&#8217;s not what they deigned to look at here. That would require actually having accomplished something that&#8217;s actually worth the 44 billion dollars in value they gained. No word yet on whether their guinea pigs are going to end up with another brand new turbo cancer in the years to come.</p><p>Until and unless mRNA technology finds a transporter other than <a href="https://pubmed.ncbi.nlm.nih.gov/38612407/">inflammatory</a> and likely <a href="https://pubmed.ncbi.nlm.nih.gov/11971999/">oncogenic</a> PEGylated LNPs, I&#8217;ve said it before, and I&#8217;ll say it again; it will <em>never</em> be a safe technology. Personalized mRNA cancer therapies might well offer better immediate survival odds than ordinary cytotoxic chemotherapies, especially in those cases with a particularly poor prognosis. Much of the autoimmune risk of the Covid shots was directly attributable to Spike <a href="https://pubmed.ncbi.nlm.nih.gov/35891400/">mimicry</a> of endogenous tissues; when you take a bioweapon, and specifically replicate and inject the gain-of-function, weaponized, worst piece of it, the horrific results were entirely predictable. Will that occur with different mRNA sequences? Nobody knows for sure. Not yet. But they haven&#8217;t touched the LNPs that <a href="https://www.mdpi.com/2076-393X/13/4/345">concentrate their payloads in cardiac and reproductive tissue</a>. No matter what they actually put inside it, that remains a known known.</p><p>After five years of lying with statistics and covering up the dangers of their last shot, I certainly wouldn&#8217;t want to be guinea pigging the next one.</p><p></p><h4>The buried lede</h4><p>With the stock rocketing to 177% of its prior-day value - largely outside normal hours, of course, thanks for playing - one thing was probably achieved.</p><p>Fauci has long had close social and professional ties with Moderna, starting in 2017 through John Mascola and the NIAID Vaccine Research Center, three years after his pardoned 2014 commencement of SARS-CoV-2 development; despite fifty years in office, with all the insider information one could hope for, his hands on the faucet for billions in research funding for decades, and biotech being one of the most lopsidedly traded sectors in existence - worthless one day, billions the next, which also happens to be how Vivek made his fortune - on a completely bunk drug, at that - apparently Fauci was a better scientist than investor, and after all that, his net worth &#8220;only,&#8221; at least officially, ended up around ~$10 million. Which is a whole lot more than mine, but that&#8217;s a pretty poor showing for the incredible amount of graft, corruption and intrigue that this man engaged in over the last fifty years.</p><p></p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!m1YF!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F24eae875-77a8-4c81-8ec9-b990be5a2675_1370x769.jpeg" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!m1YF!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F24eae875-77a8-4c81-8ec9-b990be5a2675_1370x769.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!m1YF!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F24eae875-77a8-4c81-8ec9-b990be5a2675_1370x769.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!m1YF!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F24eae875-77a8-4c81-8ec9-b990be5a2675_1370x769.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!m1YF!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F24eae875-77a8-4c81-8ec9-b990be5a2675_1370x769.jpeg 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!m1YF!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F24eae875-77a8-4c81-8ec9-b990be5a2675_1370x769.jpeg" width="1370" height="769" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/24eae875-77a8-4c81-8ec9-b990be5a2675_1370x769.jpeg&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:769,&quot;width&quot;:1370,&quot;resizeWidth&quot;:null,&quot;bytes&quot;:null,&quot;alt&quot;:&quot;.&quot;,&quot;title&quot;:null,&quot;type&quot;:null,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:null,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="." title="." srcset="/__u/substackcdn.com/image/fetch/$s_!m1YF!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F24eae875-77a8-4c81-8ec9-b990be5a2675_1370x769.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!m1YF!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F24eae875-77a8-4c81-8ec9-b990be5a2675_1370x769.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!m1YF!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F24eae875-77a8-4c81-8ec9-b990be5a2675_1370x769.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!m1YF!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F24eae875-77a8-4c81-8ec9-b990be5a2675_1370x769.jpeg 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption">It&#8217;s a big club.</figcaption></figure></div><p></p><p>With <a href="https://oklahoma.gov/oag/news/newsroom/2026/august/drummond-backs-senate-fauci-inquiry-orders-oklahoma-investigation.html">five</a> <a href="https://ebs.publicnow.com/view/CEC9F3ACA8B4CA809FDB6811F3F85262301C709D">state</a> <a href="https://www.kgou.org/health/2026-08-04/oklahoma-ag-launches-investigation-into-whether-dr-anthony-fauci-broke-state-law">attorneys general</a> now finally - FINALLY, after six long years, and countless entreaties having fallen on deaf ears - having opened criminal investigations, finally spurred to action after the revelations that <a href="https://www.ronjohnson.senate.gov/2026/08/10/senators-johnson-paul-release-initial-texts-from-dr-faucis-government-iphone-2/">Fauci was well aware of the vaccines&#8217; abortifacient properties</a> - 82%, a <a href="https://www.uclahealth.org/medical-services/obgyn/family-planning/patient-resources/medical-abortion">similar mortality rate to dedicated abortion drugs</a>, and an <a href="https://www.hsgac.senate.gov/subcommittees/investigations/hearings/the-corruption-of-science-and-federal-health-agencies-how-health-officials-downplayed-and-hid-myocarditis-and-other-adverse-events-associated-with-the-covid-19-vaccines/thorp-testimony/">accurate number</a>, despite the concerted and controlled opposition attempts to muddy the waters around it - and having <a href="https://www.cbsnews.com/news/fauci-covid-vaccine-questions-live-stream-today-2021-02-25/">blatantly lied</a> to pregnant mothers that it was safe, leaving them to be coerced and cajoled along with the rest of us, to untold numbers of murdered babies - $10 million isn&#8217;t going to hold up long against the mountain of legal fees he&#8217;s got coming.</p><p></p><p>With a single, enormously overhyped announcement, that there is no <em>way</em> on planet Earth he was not aware of beforehand, a cool five or six figures <a href="https://www.reddit.com/r/wallstreetbets/comments/1vsr64j/500k_overnight_mrna/">in the right call options</a> will have turned into untold millions of dollars that day. Now <em>that</em> should quite comfortably cover some lawyers.</p><p></p><p>For those state attorneys general that have picked up the thread - and maybe, just maybe, if anyone at DOJ is still paying attention - that pardon does <em>not</em> cover anything that happened yesterday - I would be <em>pretty darned sure</em> that some serious insider trading just happened in those early-morning, off-market hours, or perhaps in the days or weeks beforehand. With an apparently free and clear autopen pardon for every bioweapon experiment from 2014 on, until Weekend at Biden&#8217;s was finally pried from office, <a href="https://www.thewrap.com/media-platforms/journalism/donald-trump-respects-biden-for-anthony-fauci-pardon/">&#8220;respected&#8221;</a> by a president looking forward to depending on those powers for <a href="https://www.wsj.com/finance/stocks/how-wall-streets-bots-are-cashing-in-on-trumps-truth-social-posts-572f9dfd">his own</a> trading schemes, the only remaining avenues for justice against this man are either the States, or any brand new federal crimes that happen to pop up.</p><p></p><p>I don&#8217;t have a lick of proof of that. I have absolutely no evidentiary basis, whatsoever, to say it. A Bloomberg terminal might shed some, vague, light on it; that Fauci or his backers just made seven or eight figures on a bogus Moderna media blitz, in a stock market movement that was almost completely unavailable to the common man, is pure conjecture and opinion. But if you, dear reader, happen to be one of the many, many people that are well-enough placed to take a look at those books, or the books of whatever byzantine series of shell corps ends up funding his defense &#8230; </p><p></p><p>Alongside the blatant contempt of Congress, <a href="https://x.com/TheInsiderPaper/status/2085514775719752008?s=20">slowly</a> making its <a href="https://x.com/LeadingReport/status/2089012438930718864?s=20">way</a> through the <a href="https://x.com/VladTheInflator/status/2006395554574573976/photo/1">halls of absolutely nothing,</a> that just might be mistake number two.</p><p></p><div><hr></div><p><em>Sitrep and a personal note follows.</em></p>
      <p>
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   ]]></content:encoded></item><item><title><![CDATA[Curing the Incurable: Alpha-Gal Syndrome]]></title><description><![CDATA[Sometimes the answer lies somewhere unexpected.]]></description><link>https://veryvirology.substack.com/p/curing-the-incurable-alpha-gal-syndrome</link><guid isPermaLink="false">https://veryvirology.substack.com/p/curing-the-incurable-alpha-gal-syndrome</guid><dc:creator><![CDATA[Adam Gaertner]]></dc:creator><pubDate>Sat, 30 May 2026 16:43:14 GMT</pubDate><enclosure url="https://substackcdn.com/image/fetch/$s_!utrF!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd7f28a3e-ac6a-4636-a1b8-763ea61bde70_610x407.jpeg" length="0" type="image/jpeg"/><content:encoded><![CDATA[<p>Since farmers and homesteaders have <a href="https://x.com/DominguezH31015/status/2059421216474013989">started</a> <a href="https://x.com/DRanchLife/status/2060463096724881828">finding</a> boxes of ticks on their lands, having apparently been deposited by aircraft, and the range of the Lone Star Tick appears to be being greatly expanded by a campaign to which nobody, as yet, appears to be &#8216;fessing up, I&#8217;ve been taking a close look at the immunology and the processes by which Alpha-Gal Syndrome manifests and persists. After an attempted Hantavirus scare, defused by the eventual release of several patient-sampled genomes, and subsequent analyses thereof - both mine and others&#8217; - determining that no gain of function funny business had been attempted, and the virus, dangerous as it <em>could</em> be, was still just your garden-variety, fomite-primary rat poop risk - pour one out for the cruise ship passengers, who were very definitely not being served the Chef Rattatoulie special -  and now an Ebola outbreak, being fearmongered from some unexpected quarters - alpha-gal syndrome, <a href="https://x.com/franko_ufo/status/2043398579914428551">lionized by the WEF</a> for its potential to reduce the plebeians&#8217; cow consumption, that sickens you for eating real meat - <em>or</em> <em>basically</em> <em>any animal product whatsoever -</em> does still appear to be a real and present risk, and the case count has been dramatically accelerating of late.</p><p>I expected to find an answer in proteomic immunology, and while my study has yielded some surprising insights into immune compartments that I had not particularly deeply engaged with - and also a potential pharmaceutical cure, albeit one for which &#8216;overkill&#8217; would be an understatement - my findings on curing it have been quite surprising, inasmuch for their sources as the method by which it works. Nevertheless, the science, and the first hand reports check out, and despite some very understandable skepticism, we do already appear to have a reliable, well-reputed cure.</p><p>So, without further ado&#8230;</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!utrF!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd7f28a3e-ac6a-4636-a1b8-763ea61bde70_610x407.jpeg" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!utrF!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd7f28a3e-ac6a-4636-a1b8-763ea61bde70_610x407.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!utrF!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd7f28a3e-ac6a-4636-a1b8-763ea61bde70_610x407.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!utrF!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd7f28a3e-ac6a-4636-a1b8-763ea61bde70_610x407.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!utrF!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd7f28a3e-ac6a-4636-a1b8-763ea61bde70_610x407.jpeg 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!utrF!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd7f28a3e-ac6a-4636-a1b8-763ea61bde70_610x407.jpeg" width="610" height="407" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/d7f28a3e-ac6a-4636-a1b8-763ea61bde70_610x407.jpeg&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:407,&quot;width&quot;:610,&quot;resizeWidth&quot;:null,&quot;bytes&quot;:null,&quot;alt&quot;:&quot;Living on Earth: Guinea Fowl and Tick Control&quot;,&quot;title&quot;:null,&quot;type&quot;:null,&quot;href&quot;:null,&quot;belowTheFold&quot;:false,&quot;topImage&quot;:true,&quot;internalRedirect&quot;:null,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="Living on Earth: Guinea Fowl and Tick Control" title="Living on Earth: Guinea Fowl and Tick Control" srcset="/__u/substackcdn.com/image/fetch/$s_!utrF!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd7f28a3e-ac6a-4636-a1b8-763ea61bde70_610x407.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!utrF!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd7f28a3e-ac6a-4636-a1b8-763ea61bde70_610x407.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!utrF!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd7f28a3e-ac6a-4636-a1b8-763ea61bde70_610x407.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!utrF!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd7f28a3e-ac6a-4636-a1b8-763ea61bde70_610x407.jpeg 1456w" sizes="100vw" fetchpriority="high"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption">Guinea fowl, voracious tick connoisseurs, deployed to the front lines. <a href="https://www.loe.org/shows/segments.html?programID=19-P13-00030&amp;segmentID=7">Source</a> </figcaption></figure></div><p></p><h2>Alpha-Gal Syndrome</h2><p>Alpha-Gal Syndrome, or AGS, is a primarily mast-cell mediated immunological disorder, induced by the contents of the saliva of the Lone Star Tick. Unlike most immune disorders, which target a protein of some description, the antagonist here is a sugar, alpha-gal, or more precisely, galactose-alpha-1,3-galactose. The sugar is found in the meat, skin and tissues of just about every mammal on Earth. Characterization of the disease was relatively recent, only having been clearly attributed and described in 2009 by Commins et al., though early work did go back as far as 1985; while of course it has existed, undiscovered, for a millennia, the long delay between &#8220;infection&#8221; and symptomatic reaction had kept it largely unattributed to its true source. It is also, and also correctly, classified as an allergy; with symptoms primarily mediated by histamine and mast cell degranulation, it presents and acts similarly to any other allergy, with symptoms ranging from hives and discomfort to anaphylaxis and death.</p><p>The first thing that you should know, is that it is not exclusively an allergy to meat; with the alpha-gal sugar practically ubiquitous across mammalian biology and cells of all kinds, the allergy causes a life-threatening reaction to <strong>almost any mammalian animal product.</strong> Whether or not that fact is known to the psychopaths gleefully discussing it at the WEF, or if they only ever cared to hear the short version and tunnel-vision on the glorious, carbon-free vegan future we could all share, remains unknown; but anyone who would <em>deliberately induce this across an entire population</em> needs to have their head checked. Preferably in the course of their pre-trial processing for crimes against humanity. But I digress.</p><p>With the disease only relatively recently understood, surveillance and diagnosis has been patchy, both across the US and in our neighboring countries, which are presently the exclusive domain of the lone star tick, and so while accurate data on prevalence is hard to come by, one thing is clear: the range of the tick, and consequently the prevalence of AGS, has been dramatically expanding of late, and more and more people are being discovered to be suffering from it.</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!C6Re!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F3f0088ec-6c17-41da-8334-f204c8325d3d_1280x720.webp" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!C6Re!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F3f0088ec-6c17-41da-8334-f204c8325d3d_1280x720.webp 424w, /__u/substackcdn.com/image/fetch/$s_!C6Re!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F3f0088ec-6c17-41da-8334-f204c8325d3d_1280x720.webp 848w, /__u/substackcdn.com/image/fetch/$s_!C6Re!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F3f0088ec-6c17-41da-8334-f204c8325d3d_1280x720.webp 1272w, /__u/substackcdn.com/image/fetch/$s_!C6Re!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F3f0088ec-6c17-41da-8334-f204c8325d3d_1280x720.webp 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!C6Re!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F3f0088ec-6c17-41da-8334-f204c8325d3d_1280x720.webp" width="1280" height="720" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/3f0088ec-6c17-41da-8334-f204c8325d3d_1280x720.webp&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:720,&quot;width&quot;:1280,&quot;resizeWidth&quot;:null,&quot;bytes&quot;:null,&quot;alt&quot;:&quot;Alpha-gal Syndrome Allergy Market Size, Share and Forecast 2026 to 2035&quot;,&quot;title&quot;:null,&quot;type&quot;:null,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:null,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="Alpha-gal Syndrome Allergy Market Size, Share and Forecast 2026 to 2035" title="Alpha-gal Syndrome Allergy Market Size, Share and Forecast 2026 to 2035" srcset="/__u/substackcdn.com/image/fetch/$s_!C6Re!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F3f0088ec-6c17-41da-8334-f204c8325d3d_1280x720.webp 424w, /__u/substackcdn.com/image/fetch/$s_!C6Re!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F3f0088ec-6c17-41da-8334-f204c8325d3d_1280x720.webp 848w, /__u/substackcdn.com/image/fetch/$s_!C6Re!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F3f0088ec-6c17-41da-8334-f204c8325d3d_1280x720.webp 1272w, /__u/substackcdn.com/image/fetch/$s_!C6Re!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F3f0088ec-6c17-41da-8334-f204c8325d3d_1280x720.webp 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption">That&#8217;s a valuable market they&#8217;re building. <a href="https://www.insightaceanalytic.com/report/alpha-gal-syndrome-allergy-market/3498">Source</a></figcaption></figure></div><p>The disease presentation is, too, unique: rather than the near-immediate allergic reactions with which most sufferers of serious allergies are familiar, whether to pollen, or bee stings, or peanuts, etc., onset is typically substantially delayed. Symptoms tend to present up to three to six hours after consumption of an allergenic animal product. This is due primarily to the digestive process. Alpha-gal is expressed as a terminal residue at the end of long-chain, protein-bound sugars. Those proteins are digested in the stomach; the alpha-gal itself proceeds from there, untouched, to the gut. Only upon encountering the enterocyte of the gut, and being absorbed into a chylomicron for passage into the bloodstream, does it become pathogenic; the AG epitope, being strongly hydrophilic, is complexed into the chylomicron phospholipid monolayer, and the reactive site is exposed, ready for immune attack, on the surface of that chylomicron, which is otherwise just supposed to be carrying lunch.</p><p>Another interesting fact, and fundamental to the pathogenesis upon exposure to the tick&#8217;s saliva, is that we all already do possess an &#8220;immunity&#8221; to the alpha-gal sugar. In the course of ordinary, unaffected life, the only meaningful expression of that immunity is mediated by memory B-cells, created from the earliest stages of our gut microbiome development, along with the myriad other residual immune defenses we possess against diseases that we probably haven&#8217;t seen in several million years. That immunity is expressed - very rarely - via ordinary IgG and IgM antibodies; the sugar is of no metabolic use to us, due to our lack of the necessary glycosidase, so our ordinary reaction is for T-cells or macrophages to harmlessly, silently destroy it. This process happens pretty much all day, every day, for everyone but the strictest vegans, and is of no danger whatsoever. Anti-AG IgG and IgM Abs are a ubiquitous, normal part of our baseline serological profile.</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!BRly!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd329b7b5-1004-4a1c-8f0d-d5a6f4690d8c_1500x1000.png" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!BRly!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd329b7b5-1004-4a1c-8f0d-d5a6f4690d8c_1500x1000.png 424w, /__u/substackcdn.com/image/fetch/$s_!BRly!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd329b7b5-1004-4a1c-8f0d-d5a6f4690d8c_1500x1000.png 848w, /__u/substackcdn.com/image/fetch/$s_!BRly!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd329b7b5-1004-4a1c-8f0d-d5a6f4690d8c_1500x1000.png 1272w, /__u/substackcdn.com/image/fetch/$s_!BRly!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd329b7b5-1004-4a1c-8f0d-d5a6f4690d8c_1500x1000.png 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!BRly!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd329b7b5-1004-4a1c-8f0d-d5a6f4690d8c_1500x1000.png" width="1456" height="971" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/d329b7b5-1004-4a1c-8f0d-d5a6f4690d8c_1500x1000.png&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:971,&quot;width&quot;:1456,&quot;resizeWidth&quot;:null,&quot;bytes&quot;:null,&quot;alt&quot;:&quot;Types of Antibodies and Their Functions&quot;,&quot;title&quot;:null,&quot;type&quot;:null,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:null,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="Types of Antibodies and Their Functions" title="Types of Antibodies and Their Functions" srcset="/__u/substackcdn.com/image/fetch/$s_!BRly!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd329b7b5-1004-4a1c-8f0d-d5a6f4690d8c_1500x1000.png 424w, /__u/substackcdn.com/image/fetch/$s_!BRly!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd329b7b5-1004-4a1c-8f0d-d5a6f4690d8c_1500x1000.png 848w, /__u/substackcdn.com/image/fetch/$s_!BRly!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd329b7b5-1004-4a1c-8f0d-d5a6f4690d8c_1500x1000.png 1272w, /__u/substackcdn.com/image/fetch/$s_!BRly!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd329b7b5-1004-4a1c-8f0d-d5a6f4690d8c_1500x1000.png 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption">Various antibodies and what they&#8217;re here for. <a href="https://sciencenotes.org/types-of-antibodies-and-their-functions/">Source</a></figcaption></figure></div><p></p><h2>Immunology</h2><p>The disease itself is, upon contact with the tick&#8217;s unique saliva, the product of an unfortunate, prolonged cascade of immunological errors. The tick&#8217;s saliva contains a signaling molecule, PGE2, present primarily because it helps prevent clotting, and modifies the immune response, allowing the tick to feast on your blood in peace. When the bite injury occurs, immune cells of all stripes are rapidly recruited to the site, to assess the potential for infection, commence the healing process, and attack any intruders. Among those cells are immature dendritic cells, or DCs, the local interpretive brain of the immune response. They are present to collect, analyze, and pass to the lymphatic nodes whatever random debris they happen to encounter; the adaptive immune response here can be said to start from the DC.</p><p>Whilst present at the site, the immunological signaling environment irrevocably influences the DC&#8217;s maturation process. The cell&#8217;s development is influenced by the general vibe of the area, and how it&#8217;s received later in the lymph node varies dramatically on that basis. Broadly, there are three possible environments; TH0, with no particular bias, TH1, with a pro-inflammatory bias, and TH2, with an allergic bias. The first step in that cascade is the inducement of a TH2 bias in those immature DCs. A simple bite wound would ordinarily present an inflammatory TH1 bias; TH2 is not at all the correct characterization that should be carried back.</p><p>Subsequent to that exposure, and having collected a sample of the alpha-gal sugar, the DC slowly makes its way through the skin toward the nearest lymph node, and finishes its maturation along the way. This process takes days, and it is, technically, vulnerable to physical destruction during this phase; while inflicting gross tissue destruction against one&#8217;s own skin is generally inadvisable, it is an early-stage possibility. Of course, to even consider that an option would presume that you had noticed the tick bite, and while you may presently be on alert, not everyone is quite so lucky, and the initial bite frequently goes completely unnoticed.</p><p></p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://veryvirology.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">To receive new articles and support this work, please consider becoming a free or paid subscriber. It makes a difference!</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div><p></p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!WNRE!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F984834d2-5d71-44dc-b928-c15a622382a3_2500x2500.jpeg" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!WNRE!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F984834d2-5d71-44dc-b928-c15a622382a3_2500x2500.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!WNRE!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F984834d2-5d71-44dc-b928-c15a622382a3_2500x2500.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!WNRE!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F984834d2-5d71-44dc-b928-c15a622382a3_2500x2500.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!WNRE!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F984834d2-5d71-44dc-b928-c15a622382a3_2500x2500.jpeg 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!WNRE!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F984834d2-5d71-44dc-b928-c15a622382a3_2500x2500.jpeg" width="1456" height="1456" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/984834d2-5d71-44dc-b928-c15a622382a3_2500x2500.jpeg&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:1456,&quot;width&quot;:1456,&quot;resizeWidth&quot;:null,&quot;bytes&quot;:null,&quot;alt&quot;:&quot;Understanding the Lymphatic System &#8212; Acupuncture | Rochester, NY&quot;,&quot;title&quot;:null,&quot;type&quot;:null,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:null,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="Understanding the Lymphatic System &#8212; Acupuncture | Rochester, NY" title="Understanding the Lymphatic System &#8212; Acupuncture | Rochester, NY" srcset="/__u/substackcdn.com/image/fetch/$s_!WNRE!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F984834d2-5d71-44dc-b928-c15a622382a3_2500x2500.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!WNRE!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F984834d2-5d71-44dc-b928-c15a622382a3_2500x2500.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!WNRE!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F984834d2-5d71-44dc-b928-c15a622382a3_2500x2500.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!WNRE!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F984834d2-5d71-44dc-b928-c15a622382a3_2500x2500.jpeg 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption">A map of all of your lymph nodes. Catch it if you can... Interestingly: <a href="https://acu585.com/acupuncture-rochester-ny-blog/2025/1/23/understanding-the-lymphatic-system">Source</a></figcaption></figure></div><p></p><p>Once it arrives, it has matured, and the bad news begins. Your body knows what alpha-gal looks like; every lymph node has a memory B-cell or two that will recognize it. Ordinarily, some IgG or IgM antibodies would be released, and that would be the end of it. However, this time is different: that Th2-biased DC has a story to tell. Those memory B-cells, most of which sit dormant for decades, each tuned to spot any of a trillion potential antigens, which would ordinarily activate, reproduce, and flood the body with IgM or IgG, will instead do something strange. They still replicate, but under the Th2 bias, their daughter cells are no ordinary B-cells: instead of IgG or IgM, they now produce IgE antibodies. The newly produced cells face an immediate choice: death by apoptosis at the GC checkpoint, the usual response to an out-of-line reaction, or clonal selection survival. About half will die there and then. Those that survive that fork are no longer B-cells: they are now <strong>plasma cells.</strong> Their differentiation into IgE-secreting plasma cells also comes with a unique, and to us here, a potentially useful drawback; being bearers of a particularly damaging mode of immunity, and so bound to live as outcasts, they are made deeply deficient in CXCR4, which is the primary chemotaxic facilitator of such a cell&#8217;s initial journey to a new home; without it, to cut a very long story short, they will never quite find anywhere to thrive and call home.</p><p>As an interesting side note, CXCL12/SDF-1 in the tick&#8217;s saliva (as well as PGE2, the primary antagonist of this story, albeit to a lesser degree) does in fact tend to upregulate CXCR4 expression on plasma cells. However, the plasma cells we&#8217;re concerned about do not actually exist - at least, not yet, until fresh bites are being inflicted on a person already suffering from alpha-gal. That fact may actually be a bit of bad news: whilst we&#8217;ll cover CXCR4 in more detail in the following section, it may be the case that further tick bites, whilst already suffering from AGS, may further entrench the disease by enhancing LLPC migration to bone marrow.</p><p></p><h2>Plasma Cells</h2><p>Plasma cells are the ghosts of a B-cell. Nominally the same internally, they are B-cells that have been stripped of most of their receptors - including, as I mentioned, CXCR4 - and stripped of most of the internal cellular machinery that permits a cell to persist independently. Their only function in life now is to continually flood the body with the antibodies designed by their parent, for so long as the body wants to keep them alive. After that process of differentiation, they are released into the blood to fend for themselves, continually consuming themselves to fulfill their mission.</p><p>Most of them will get there, and then die there. Those are the <strong>SLPC</strong>s - short lived plasma cells. The lack of that cellular survival machinery - endogenous Bcl-2  anti-apoptotic signaling primarily - means that those cells unable to find a <strong>survival</strong> <strong>niche</strong> will rapidly burn out, generally within 2-3 days. The delicate balance of homeostasis, which I covered <a href="/__u/veryvirology.substack.com/p/igg4-antibody-class-switch-end-of?r=1g2ec3">here</a>, requires continual signaling - not even nutritional necessities, but just the barest-bones, &#8220;you are still needed here&#8221; anti-apoptotic signaling - for a cell to avoid an apoptotic fail-safe death. Most cells have the self-esteem to produce that for themselves. PCs do not. SLPCs mediate the most intense, initial phase of the disease, with systemic antibody titers at their highest. They die within days.</p><p>The true mediators of long-term disease are the <strong>LLPC</strong>s, or long lived plasma cells. They are exactly the same as the SLPCs, but by pure chance of fate, they happened to float around in the blood and land in a particular survival niche, generally somewhere in a lymphatic node, or often in bone marrow. This is where CXCR4 comes in.</p><p>Immunity to innumerable different diseases is mediated, on the front line, by LLPCs, including ones that we&#8217;ve probably never heard of or even know to exist. LLPCs are the means by which a given antibody will continue to persist in serum, or in any given tissue, long after the pathogen has been eradicated from the body. They are, as we covered, sourced from B-cells; the difference, though, is that while B-cells will react to a new exposure, after a delay of a few days, during which time the pathogen is more or less free to run rampant, LLPCs need nothing but the warmth and affirmations of their niche to keep those antibodies immediately present from now until the end of time. This is important for diseases like tetanus, where the interceding delay between exposure and B-cell reaction is simply too late to stop the toxin from doing its deadly damage. If mRNA was a viable vaccine platform, and the Covid vaccines were actually meant to provide protection, rather than serve as tools of genocide and death, long-lasting immunity would have been mediated by LLPCs. They know how to make that happen. They just didn&#8217;t. But I digress.</p><p>Most of the LLPC population is formed at birth, through - you guessed it - the placenta, and exposure to same. That rush of antigens fires up the baby&#8217;s B-cell population, the B-cells produce plasma cells, and - <strong>using CXCR4 chemotaxis like a compass - </strong>those plasma cells find their way into lymph nodes and bone marrow, providing a life of immunity to the cornucopia of diseases we&#8217;ve known since the beginning of time. In the course of this work, I did develop a method by which that LLPC population - <strong>which is where the functional persistence of AGS resides</strong> - could be wholesale nuked from orbit. While the B-cells would remain intact - <em>albeit not in any IgE expressing form -</em> it would be nuclear fire for the entirety of the front-line, antibody-based adaptive immune system. Every single pathogen in existence, bar those we can deal with by innate immunity alone, would sicken us for a few days before the B-cells kicked into high gear. Including, possibly, those that we happily live with, on our skin and in our gut, every minute of every day. In considering this, I was musing that were one to undergo this proposed therapy, it might be wise thereafter to - literally - have a newly ejected placenta thrown in one&#8217;s face, like a bloody, disgusting, wholesome immunological pie&#8230;</p><p></p><p>&#8230;I&#8217;m not gonna illustrate that one. It&#8217;s a joke. The immunodeficiency following that process would be staggering, and needless to say, I think that&#8217;s probably overkill. But - so far as I can tell, it is not a therapy that exists or has been presently recognized - and despite the overwhelming drawbacks, there may be someone out there, for some other condition, for whom it might be worth it - lupus? - so if you are a treating MD that might consider that a viable approach for whatever you happen to be dealing with, please feel free to reach out, and I will be happy to take a look.</p><p></p><p>From there, it&#8217;s all history: mast cells&#8217; Fc receptors bind, and are populated by, the emitted anti-alpha-gal IgE antibodies, and the allergic gun is now loaded, to be fired upon the presentation of the offending sugar. Interestingly, monovalent alpha-gal - a sugar chain that presents only a single alpha-gal binding site - will not induce the mast cell degranulation reaction that defines the disease. Only a heterovalent alpha-gal presenter, where several adjacent, IgE-populated Fc receptors are bound simultaneously, will set off the potentially lethal, and at any rate deeply unpleasant, reaction. This was an interesting rabbit hole to go down, examining the possibility of any tolerable gut bacterium, or chemicals or drugs, that could induce a hydrolyzing reaction alongside the offending food product, splitting up the sugar into monovalent structures that would cause no harm; alas, it was not to be. At least, not so far as I found; and at any rate, the maximal therapeutic application of that would be to make a sufferer eat something else alongside their meal, to mitigate the reaction. I don&#8217;t want that. I want a preventative, and I want a cure.</p><p>So, with a nuclear option discovered, and a fruitless rabbit hole explored, the search for a cure goes on.</p><p></p><h2>So, back to the drawing board&#8230;</h2><p>&#8230; or maybe just to the message board!</p><p>Twice over these last six years, I have identified cures, first for Covid and then for cancer, and taken to social media to start the process of disseminating them. A lot of people found my work via Twitter, and then X, even despite the heavy-handed censorship. As the public square and marketplace of ideas, a day on Twitter will yield everything from the ins and outs of the oil industry (<em>which, incidentally, is about to implode, don&#8217;t look down..)</em> to the latest developments on birds <a href="https://x.com/NatashaCL7/status/2057551440478933206">not, in fact, being real</a>&#8230;</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!1a_p!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F02e93809-87f6-4247-9ce4-2e2cd21a00e9_421x421.gif" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!1a_p!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F02e93809-87f6-4247-9ce4-2e2cd21a00e9_421x421.gif 424w, /__u/substackcdn.com/image/fetch/$s_!1a_p!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F02e93809-87f6-4247-9ce4-2e2cd21a00e9_421x421.gif 848w, /__u/substackcdn.com/image/fetch/$s_!1a_p!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F02e93809-87f6-4247-9ce4-2e2cd21a00e9_421x421.gif 1272w, /__u/substackcdn.com/image/fetch/$s_!1a_p!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F02e93809-87f6-4247-9ce4-2e2cd21a00e9_421x421.gif 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!1a_p!,w_1456,c_limit,f_auto,q_auto:good,fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F02e93809-87f6-4247-9ce4-2e2cd21a00e9_421x421.gif" width="421" height="421" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/02e93809-87f6-4247-9ce4-2e2cd21a00e9_421x421.gif&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:421,&quot;width&quot;:421,&quot;resizeWidth&quot;:null,&quot;bytes&quot;:8751173,&quot;alt&quot;:null,&quot;title&quot;:null,&quot;type&quot;:&quot;image/gif&quot;,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:&quot;https://veryvirology.substack.com/i/199808921?img=https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F02e93809-87f6-4247-9ce4-2e2cd21a00e9_421x421.gif&quot;,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="" srcset="/__u/substackcdn.com/image/fetch/$s_!1a_p!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F02e93809-87f6-4247-9ce4-2e2cd21a00e9_421x421.gif 424w, /__u/substackcdn.com/image/fetch/$s_!1a_p!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F02e93809-87f6-4247-9ce4-2e2cd21a00e9_421x421.gif 848w, /__u/substackcdn.com/image/fetch/$s_!1a_p!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F02e93809-87f6-4247-9ce4-2e2cd21a00e9_421x421.gif 1272w, /__u/substackcdn.com/image/fetch/$s_!1a_p!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F02e93809-87f6-4247-9ce4-2e2cd21a00e9_421x421.gif 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption">They have remote-control roaches now, too.</figcaption></figure></div><p></p><p>In the case of AGS, you will also find the accounts of the numerous people that have been afflicted by the condition; the WEFites contemplating poisoning us all with it; RFK about to announce an mRNA cure for it; the destroyed, airdropped crates of the causative ticks; cute videos of the birds that are being deployed to eat those ticks&#8230;</p><p>&#8230;and, curiously, one account after another of a little-known acupuncture method, being hailed as a cure.</p><p></p><h2>Really?</h2><p>I&#8217;ve gone down my share of rabbit holes from conspiracy Twitter. From the reports of becoming magnetized upon Covid vaccination - which I investigated, and dismissed as a deeply elaborate hoax, until a little-noted publication appears to have confirmed and documented it - to the painful discreditors of skepticism itself that would like you to believe that viruses aren&#8217;t real.</p><p>Having resisted any media presence for most of my life, until my wife convinced me to throw my hat in the ring to end the Covid pandemic, I&#8217;ve nonetheless now spent enough time on it, I think, to start to get a sense for when a narrative is being professionally astroturfed, or when some delusional shut-in and their 200 followers are pushing some insane theory or another. I didn&#8217;t get that sense here; just one after another, farmers or ranchers or bored housewives chatting it up at 2pm, these accounts just kept popping up.</p><p>So, I decided to investigate: do we already have a cure? How can a needle in the ear translate to clearing out the LLPC compartment and deactivating a dangerously armed mast cell population?</p><p>After having done so, I have to say that I&#8217;m convinced. In my opinion, we do, in fact, have a cure - and a pretty well documented one, at that. I didn&#8217;t discover it, but I would be remiss to fail to document it; especially given the HHS announcement today, that they&#8217;re &#8220;working on&#8221; a cure, which will probably end up being some new scheme to push a new, multi-billion-dollar, government-funded mRNA therapy, I think it needs said. The extent of already-existing documentation was also quite shocking. Whilst it&#8217;s clearly never had the front-page MSM treatment, there have been numerous, formal, well-designed studies done; to the extent that HHS might ostensibly have been aiming to tamp down any fears about alpha-gal, or to act like they&#8217;re doing something useful, their complete failure to mention it is surprising, to say the least. I like RFK, but he&#8217;s still a man with a boss, and his boss is the number one fan of mRNA and pharma, which doesn&#8217;t go anywhere good.</p><p>I think that this needs to be known, and credibly, widely integrated into practice, before they finish whatever they&#8217;ve started working on. When they stand up to say they&#8217;ve got themselves another cancer-causing mRNA shot, the ideal reaction, IMO, would be a collective shrug and a continuation of what&#8217;s already being done.</p><p></p><p>With that said: let&#8217;s get into it.</p><p></p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://veryvirology.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">To receive new articles and support this work, please consider becoming a free or paid subscriber. It makes a difference!</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div><p></p><h2>SAAT: Soliman Auricular Allergy Treatment</h2><p>The difference between an allergy and an immunopathology is, in the end, generally academic. It&#8217;s largely all immune-mediated. IgG 1-4, IgM, IgG; mast cells, T-cells or neutrophils; it&#8217;s fundamentally just a matter of which compartment is doing what we might rather it not. Allergies, with a few specific (but common) exceptions, are immunopathologies all the same, and many of the same mechanisms apply.</p><p>The pertinent operator here is IgG4 tolerance. It has been discussed at length in the past; sometimes in a good context, sometimes in a bad context, but always in an immunological one. IgG4 lives at the end of a sequence of antibody class-switching; when an antigen has been continually present for a prolonged period of time, and the world hasn&#8217;t ended because of it, the immune system eventually gets tired of crying wolf and decides to shut off. It is the anti-antibody; whereas every other antibody directs immune attack, IgG4 by-and-large does the opposite, marking its quarry as harmless and precluding an immune attack.</p><p>Tolerogenic allergen therapy was, upon starting in on alpha-gal, my first thought. It works almost universally, because of that progression to IgG4; continual exposure to the offending article will usually, eventually, induce the switch and erase the allergic reaction. Of course, it entails continuous or repeated exposure to something that generally has the potential to kill you in anaphylactic shock, or in the least, causing extreme discomfort and allergic reaction, so it&#8217;s easier said than done. That would have been too easy, I thought. I guess not.</p><p>Acupuncture has a vast number of specific methods, applications, locations, and so forth. If you aren&#8217;t familiar with it, it&#8217;s the practice of inserting needles into various precisely mapped out places across the body, and it has claimed to have cured everything from a bad mood to cancer and everything between, all of wildly varying veracity. One account I scrolled past. Two? Three, four, five? Alright, let&#8217;s take a look. I am no expert on acupuncture, and I don&#8217;t plan to become one; I take absolutely no position on anything else across the wide, wide world of its applications; but what I&#8217;ve found here is, in my opinion, very strongly indicative of an effective treatment.</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!-D0H!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F669babf1-5a71-4056-817f-8430d74dadaf_1600x760.jpeg" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!-D0H!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F669babf1-5a71-4056-817f-8430d74dadaf_1600x760.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!-D0H!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F669babf1-5a71-4056-817f-8430d74dadaf_1600x760.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!-D0H!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F669babf1-5a71-4056-817f-8430d74dadaf_1600x760.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!-D0H!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F669babf1-5a71-4056-817f-8430d74dadaf_1600x760.jpeg 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!-D0H!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F669babf1-5a71-4056-817f-8430d74dadaf_1600x760.jpeg" width="1456" height="692" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/669babf1-5a71-4056-817f-8430d74dadaf_1600x760.jpeg&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:692,&quot;width&quot;:1456,&quot;resizeWidth&quot;:null,&quot;bytes&quot;:null,&quot;alt&quot;:&quot;14 Surprising Uses for Acupuncture - Health News Hub&quot;,&quot;title&quot;:null,&quot;type&quot;:null,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:null,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="14 Surprising Uses for Acupuncture - Health News Hub" title="14 Surprising Uses for Acupuncture - Health News Hub" srcset="/__u/substackcdn.com/image/fetch/$s_!-D0H!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F669babf1-5a71-4056-817f-8430d74dadaf_1600x760.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!-D0H!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F669babf1-5a71-4056-817f-8430d74dadaf_1600x760.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!-D0H!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F669babf1-5a71-4056-817f-8430d74dadaf_1600x760.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!-D0H!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F669babf1-5a71-4056-817f-8430d74dadaf_1600x760.jpeg 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption">Harikiri never looked so good.</figcaption></figure></div><p></p><p>The first thing to note about it is the location. This one is in the ear, specifically at a site that is innervated by the vagus nerve; notably, into the only exterior-accessible vagus nerve innervation that is not first collated into the spinal column. This nerve pathway travels from there into the nucleus tractus solitarius (NTS) which - imagine my surprise - is responsible for cholinergic anti-inflammatory pathway. The needle, tiny at 3mm long, is inserted into this site in the ear, doped with a sample of the offending antigen - the alpha-gal sugar - and mechanically held in place for several months subsequently.</p>
      <p>
          <a href="/__u/veryvirology.substack.com/p/curing-the-incurable-alpha-gal-syndrome">
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   ]]></content:encoded></item><item><title><![CDATA[A Policy Prescription For The Future]]></title><description><![CDATA[The real blueprint, not the WEF's delusional dreams.]]></description><link>https://veryvirology.substack.com/p/a-policy-prescription-for-the-future</link><guid isPermaLink="false">https://veryvirology.substack.com/p/a-policy-prescription-for-the-future</guid><dc:creator><![CDATA[Adam Gaertner]]></dc:creator><pubDate>Mon, 08 Dec 2025 11:23:28 GMT</pubDate><enclosure url="https://substackcdn.com/image/fetch/$s_!2z_t!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F527686fd-6f85-4915-af92-6695014dc174_1280x640.jpeg" length="0" type="image/jpeg"/><content:encoded><![CDATA[<p>Between the launch of the multi-trillion dollar Genesis AI project, and the success, after 38 development cycles at Groom Lake, of the first mass-producible nuclear SMR, extreme and pervasive automation is rapidly approaching. Every sector - <em>everything</em> - from the shelf stackers, to the lawyers, bricklayers, doctors and carers, the plumbers, the welders, or the civil engineers: <em>everyone</em> is going to be subject to AI and robotics-driven replacement, and it&#8217;s coming sooner than later.</p><p>The WEF - and, really, any thinking body that cares to model the future - is well aware of this. Their plan is clunky and oppressive: to introduce a government-controlled, programmable CBDC, to use that to hand out UBI, concentrate capital and ownership in the people at the top when the music stops, and to go forth to the new world with total control of every person&#8217;s life. You will own nothing, and you will be happy: since nobody needs the great unwashed masses anymore, those of the <em>noblesse oblige</em> will generously pacify us with drugs, video games and processed food - as opposed to just killing us all - and the ownership class, the &#8220;stakeholders,&#8221; can feel free to pursue their dreams and social experiments, howsoever they see fit, forevermore.</p><p>It&#8217;s an unrealistic, dystopian horror show, for which <a href="https://x.com/desireefixler/status/1994762949949280693">even the drafters are now apologizing</a>. And yet, the foundational premise - that the robots are going to replace us all, and the needs for human labor will be few, far between, and asymptotically approaching zero - is an unavoidable reality. No industry, no economic niche is safe. <em>None.</em></p><p>So, what do we do?</p><p></p><h3>HOW IT ACTUALLY HAPPENS</h3><p>It will not hit every sector, or every part of every sector, simultaneously. AI and robots come with <em>capex</em> - capital expenditure - that will be unevenly distributed: small businesses, which are still the backbone of the US economy, do not have mountains of money to replace the fry cook with a Tesla Optimus bot, even if the long-term math does work out. It&#8217;s just not going to happen - <em>yet</em>.</p><p>The problem with communism, as they say, is that you eventually run out of other peoples&#8217; money. That underlies a fundamental economic truth: goods and services are scarce. They require human time and effort, they come in limited quantities, whether from the mines, the production lines, or the ground, and if you just distribute free money, without a corresponding increase in goods or services, people don&#8217;t magically all gain access to infinite free stuff: the money just becomes worthless. In the midst of that transition, everyone thinks they&#8217;ve got it made, so they stop working; they stop producing as much as they were. Hyperinflation, famine and instability inevitably ensue. It&#8217;s a formula as old as the Soviet Union, Venezuela being the most recent example. Eventually, you run out of other peoples&#8217; <em>goods and services.</em></p><p>The fundamental fallacy of communism is that <em>there&#8217;s enough to go around. </em>Spoiled college kids, living on Daddy&#8217;s credit card, see their own abundance all around them, see all the deprivation in the world, and think that because there&#8217;s enough for <em>them</em>, there&#8217;s enough for <em>all</em>.</p><p>If that were actually the case, we would be living in a post-scarcity utopia<em>.</em></p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!2z_t!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F527686fd-6f85-4915-af92-6695014dc174_1280x640.jpeg" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!2z_t!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F527686fd-6f85-4915-af92-6695014dc174_1280x640.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!2z_t!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F527686fd-6f85-4915-af92-6695014dc174_1280x640.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!2z_t!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F527686fd-6f85-4915-af92-6695014dc174_1280x640.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!2z_t!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F527686fd-6f85-4915-af92-6695014dc174_1280x640.jpeg 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!2z_t!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F527686fd-6f85-4915-af92-6695014dc174_1280x640.jpeg" width="596" height="298" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/527686fd-6f85-4915-af92-6695014dc174_1280x640.jpeg&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:640,&quot;width&quot;:1280,&quot;resizeWidth&quot;:596,&quot;bytes&quot;:null,&quot;alt&quot;:&quot;Tesla's New Diner Is Serving Burgers, Showing Movies, and Has Plenty of  Robots - Barron's&quot;,&quot;title&quot;:null,&quot;type&quot;:null,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:null,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="Tesla's New Diner Is Serving Burgers, Showing Movies, and Has Plenty of  Robots - Barron's" title="Tesla's New Diner Is Serving Burgers, Showing Movies, and Has Plenty of  Robots - Barron's" srcset="/__u/substackcdn.com/image/fetch/$s_!2z_t!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F527686fd-6f85-4915-af92-6695014dc174_1280x640.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!2z_t!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F527686fd-6f85-4915-af92-6695014dc174_1280x640.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!2z_t!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F527686fd-6f85-4915-af92-6695014dc174_1280x640.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!2z_t!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F527686fd-6f85-4915-af92-6695014dc174_1280x640.jpeg 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption"><em><a href="https://www.goodreads.com/quotes/139439-there-will-be-no-curiosity-no-enjoyment-of-the-process">If you want a picture of the future, imagine a robot serving a human their burgers -</a></em><a href="https://www.goodreads.com/quotes/139439-there-will-be-no-curiosity-no-enjoyment-of-the-process"> </a><em><strong><a href="https://www.goodreads.com/quotes/139439-there-will-be-no-curiosity-no-enjoyment-of-the-process">forever</a></strong><a href="https://www.goodreads.com/quotes/139439-there-will-be-no-curiosity-no-enjoyment-of-the-process">.</a></em></figcaption></figure></div><p></p><h3>POST-SCARCITY</h3><p>Star Trek had a vision. Replicators that create all your essentials out of thin air. Warp cores that produce infinite power. A society of people that work because they <em>want </em>to, to boldly go where no man has gone before: not because they&#8217;ll starve in the cold if they don&#8217;t. The <a href="https://www.reddit.com/r/DaystromInstitute/comments/6rw7p8/the_federation_economy_post_scarcity_through_an/">science-fiction foundation of that world</a> is twofold:</p><p></p><p><strong>AUTOMATION</strong></p><p>and</p><p><strong>ENERGY.</strong></p><p></p><p>With functionally unlimited energy, and ubiquitous automation of the production of goods (and at least some services), there would, indeed, be enough to go around for all.</p><p>With mass-producible, small modular nuclear reactors <a href="https://x.com/JoshuaSteinman/status/1996797111833448880">now proven viable and nearing reality</a>, and the <a href="https://x.com/ENERGY/status/1993349144853852580">Manhattan Project of AI underway</a>, we are rapidly approaching that future. China is a long ways ahead of us: fully automated factories, pumping out thousands of, <a href="https://x.com/warintel4u/status/1848452506789286117">in this example, cruise missiles</a>, every day, powered by the sun, the wind or the water, without a man in sight; but we&#8217;re gradually catching up.</p><p>As we do, as our abundance increases and we move closer to true post-scarcity, more and more jobs disappear, and those people, whose works brought us all as far as they did, increasingly find themselves watching through the blinds as &#8220;The Future&#8221; takes off without them. Our system of capitalism, our means of capital allocation and distribution, brought us here, but it&#8217;s fraying around the edges as we move closer and closer to the singularity. In a post-scarcity world, raw capitalism - or the crony capitalism we have presently, let&#8217;s be honest - is no longer the most efficient means of economic distribution. Untouched, it will lead us directly into the WEF&#8217;s dystopian vision.</p><p>But a sudden, all-encompassing paradigm shift isn&#8217;t needed, either. Capitalism is still, by far, the best way to ease our world into this abundant vision of the future. It is, and always will be, the core expression of the human condition. How, then, do we reconcile the human experience, with the decidedly inhuman realities of an extensively automated, AI-driven future?</p><p></p><h3>THE DRY RUN</h3><p>The COVID-19 pandemic, whether intentionally or not, gave us the blueprint for how to realistically handle this. The powers-that-be treated it as a dry run for the control grid; that it was, but it was so much more than that, too.</p><p>The lockdowns were the <a href="https://www.imf.org/en/blogs/articles/2020/04/14/blog-weo-the-great-lockdown-worst-economic-downturn-since-the-great-depression">singularly most economically destructive act</a> in history. Jobs, small businesses, large businesses - some were killed overnight, some bled out under the crushing restrictions, and others - some of those others were the <em>essential workers.</em> While half the country was being paid handsomely to sit at home, and business owners were given the forgiven PPP loans to maintain their pre-lockdown incomes, howsoever lavish they may have been, pandemic policy made truly unfortunate marks out of those who had to maintain their low-wage employment. While some people - the people who <em>weren&#8217;t</em> essential - were making thousands of dollars, for doing absolutely nothing, with all their time their own, the most apparently indispensable members of society continued spending 39 hours a week working for the same subsistence pay as ever.</p><p>The people that were <em>not</em> needed made out like bandits, while the people that <em>were</em> needed continued their economic suffocation, under the same threat of starvation and homelessness, with no option to resign and join the ranks of those lavishly paid unemployed. Small wonder that the cities burned that summer.</p><p></p><p>The final rise of automation, if done properly, <em>will start in</em> <em>exactly the same way.</em></p><p></p><p><a href="https://www.investopedia.com/terms/s/structuralunemployment.asp">Structural unemployment</a>, formerly a measure of the mismatch between the skills of the people who need work, versus the jobs that are available, is <a href="https://www.sciencedirect.com/science/article/pii/S2590051X23000308">inexorably rising</a>, and will asymptotically approach 100%. Professionals and lay alike, in all fields, are already feeling the bite. Credit defaults, on student loans, credit cards, auto loans and mortgages, are hitting historic levels; and yet the economy at large, through the macro lens, seems to be doing just fine, doesn&#8217;t it? <em>People</em> are being hurt, but <em>We the People</em> are still growing in prosperity. The mismatch has economists scratching their heads. Are we in a recession? Are we not? Why is the stock market still growing?</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!iOmP!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F4b52fa1c-19f5-49eb-b301-33217f34cc72_1237x890.jpeg" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!iOmP!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F4b52fa1c-19f5-49eb-b301-33217f34cc72_1237x890.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!iOmP!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F4b52fa1c-19f5-49eb-b301-33217f34cc72_1237x890.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!iOmP!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F4b52fa1c-19f5-49eb-b301-33217f34cc72_1237x890.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!iOmP!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F4b52fa1c-19f5-49eb-b301-33217f34cc72_1237x890.jpeg 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!iOmP!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F4b52fa1c-19f5-49eb-b301-33217f34cc72_1237x890.jpeg" width="406" height="292.1099434114794" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/4b52fa1c-19f5-49eb-b301-33217f34cc72_1237x890.jpeg&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:890,&quot;width&quot;:1237,&quot;resizeWidth&quot;:406,&quot;bytes&quot;:null,&quot;alt&quot;:&quot;Image&quot;,&quot;title&quot;:null,&quot;type&quot;:null,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:null,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="Image" title="Image" srcset="/__u/substackcdn.com/image/fetch/$s_!iOmP!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F4b52fa1c-19f5-49eb-b301-33217f34cc72_1237x890.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!iOmP!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F4b52fa1c-19f5-49eb-b301-33217f34cc72_1237x890.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!iOmP!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F4b52fa1c-19f5-49eb-b301-33217f34cc72_1237x890.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!iOmP!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F4b52fa1c-19f5-49eb-b301-33217f34cc72_1237x890.jpeg 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a></figure></div><p>Oh. Nvidia - as the AI gold rush rolls on, they&#8217;re the ones selling the shovels - is now worth <em><a href="https://x.com/KobeissiLetter/status/1983941122767409201">16%</a></em><a href="https://x.com/KobeissiLetter/status/1983941122767409201"> </a><em><a href="https://x.com/KobeissiLetter/status/1983941122767409201">of the entire GDP of the United States</a>?</em> Huh. How could that possibly be?</p><p></p><p>As the total happiness in the world rises, even at this infantile stage, individual people are being hurt. One here, five here. Twenty there. Another twenty. Three hundred laid off. 4,500 gone. 60 more over here. Piecemeal, as the AI-driven automation creeps in, people are being driven out of their businesses and their jobs, which have heretofore been the primary real ways for a man to earn his living. As that automation grows, our system of capital allocation is slowly breaking down; and this time, the revolution is <a href="https://www.axios.com/2025/05/28/ai-jobs-white-collar-unemployment-anthropic">not bringing new jobs along with it</a>. They know that. As the automobile replaced the horse and buggy, the farriers lost their jobs; Henry Ford employed them to produce cars instead. That isn&#8217;t coming this time. A select, very few people, trained in linear algebra, advanced computing, and the novel fields being driven by AI, are needed to shepherd the systems, and every other job is simply being replaced. Forever. The companies who deploy AI see their salary costs collapse, and their businesses still growing. Capital concentrates upward, toward the ones who own the bots, and trickle-down economics dies its final death.</p><p></p><p>At some point soon, and sooner than you think, we are going to end up with an incredible abundance of goods, and nobody with the money to buy them. We&#8217;re not there yet, but it&#8217;s rapidly approaching, and the US government is pouring gas on that fire as fast as it can. Nobody - or, at least, not very many - wants the &#8220;UBI&#8221; that&#8217;s been proposed as a solution to this. As they say, if your government has the power to give you everything, they have the power to take from you everything, and nobody wants that. Not to mention the wild economic inefficiencies and impossibilities in UBI as it&#8217;s been proposed. Studies have proven, time and again, that given free money, people will decide not to work, or they will become less productive; simply handing out money to everyone just doesn&#8217;t work. If you give everybody $1,000 a month, then their landlords are going to raise the rent by $1,000, and if your goal was to uplift those people, you have achieved nothing. UBI is tantamount to a completely centrally planned economy, and that never ends well. Hyperinflation, as the government tries and fails to reconcile the availability of money with the availability of goods, inevitably follows.</p><p></p><p>What, then, do we do?</p><p></p><p>COVID gave us the answer.</p><p></p><h3>THE TRANSITION</h3><p>A new class of federalized unemployment insurance is created by Congress. This time, it is put in place to protect against either job loss, or small business loss, which is directly attributable to automation or AI. If your company just laid everyone off to replace you with robots - <em>congratulations.</em> If you lost your consultancy or graphic design business because your clients replaced you with AI - <em>CONGRATULATIONS!</em> You are now eligible for what we&#8217;re very definitely not calling UBI, and you can now sit at home, twiddle your thumbs, maybe finally finish that book on your shelf. Maybe get started on the family that you&#8217;ve been putting off. That weekly cash deposit from the government is more than enough to meet your needs, and then some. Your job, your career, has officially been automated away, and that&#8217;s the end of the line for you.</p><p></p><p>Welcome to day one of the rest of your life.</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!9UiQ!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F9b310688-5620-4627-b7e6-3dedefc15524_784x544.jpeg" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!9UiQ!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F9b310688-5620-4627-b7e6-3dedefc15524_784x544.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!9UiQ!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F9b310688-5620-4627-b7e6-3dedefc15524_784x544.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!9UiQ!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F9b310688-5620-4627-b7e6-3dedefc15524_784x544.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!9UiQ!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F9b310688-5620-4627-b7e6-3dedefc15524_784x544.jpeg 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!9UiQ!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F9b310688-5620-4627-b7e6-3dedefc15524_784x544.jpeg" width="408" height="283.1020408163265" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/9b310688-5620-4627-b7e6-3dedefc15524_784x544.jpeg&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:544,&quot;width&quot;:784,&quot;resizeWidth&quot;:408,&quot;bytes&quot;:95871,&quot;alt&quot;:null,&quot;title&quot;:null,&quot;type&quot;:&quot;image/jpeg&quot;,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:&quot;https://veryvirology.substack.com/i/181011281?img=https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F8a6c2abe-22c2-45d0-814c-0e21150e1455_784x1168.jpeg&quot;,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="" srcset="/__u/substackcdn.com/image/fetch/$s_!9UiQ!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F9b310688-5620-4627-b7e6-3dedefc15524_784x544.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!9UiQ!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F9b310688-5620-4627-b7e6-3dedefc15524_784x544.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!9UiQ!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F9b310688-5620-4627-b7e6-3dedefc15524_784x544.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!9UiQ!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F9b310688-5620-4627-b7e6-3dedefc15524_784x544.jpeg 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption">Free time. Is that Dr. Phil?</figcaption></figure></div><p></p><p>As automation and AI saturation enters the hockey-stick phase of its growth, this will encompass more, and more, and more people. They will be given free money by the government, likely in excess of whatever they were previously earning; they will consume goods and services, and they will produce nothing. The difference here - the reason that this is not magical economic thinking, but a vital intervention - is that the value this person previously produced for the world, whether they were an accountant, or a factory worker, or a shelf stacker, <em>is still being produced.</em> <strong>There is not, as has afflicted communist societies since the dawn of Marx, a corresponding drop in productive output!</strong> If there were to have been such a drop, then they wouldn&#8217;t have been replaced. Their job was producing some useful economic value; it has now been replaced by automation; <em>that value</em> <em>is still being produced by the robots.</em> That is the core failing of every socialist or communist society - that, and the absolute iron-fisted control that it grants to their rulers - and that is why the rising, simultaneous ubiquity of AI, automation, and soon nuclear power, is such a radical paradigm shift.</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!c95f!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fa84f5522-cd95-4c47-a41d-b26f4bd5adad_1024x898.png" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!c95f!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fa84f5522-cd95-4c47-a41d-b26f4bd5adad_1024x898.png 424w, /__u/substackcdn.com/image/fetch/$s_!c95f!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fa84f5522-cd95-4c47-a41d-b26f4bd5adad_1024x898.png 848w, /__u/substackcdn.com/image/fetch/$s_!c95f!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fa84f5522-cd95-4c47-a41d-b26f4bd5adad_1024x898.png 1272w, /__u/substackcdn.com/image/fetch/$s_!c95f!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fa84f5522-cd95-4c47-a41d-b26f4bd5adad_1024x898.png 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!c95f!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fa84f5522-cd95-4c47-a41d-b26f4bd5adad_1024x898.png" width="336" height="294.65625" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/a84f5522-cd95-4c47-a41d-b26f4bd5adad_1024x898.png&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:898,&quot;width&quot;:1024,&quot;resizeWidth&quot;:336,&quot;bytes&quot;:1049576,&quot;alt&quot;:null,&quot;title&quot;:null,&quot;type&quot;:&quot;image/png&quot;,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:&quot;https://veryvirology.substack.com/i/181011281?img=https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fcc18fbd6-d5fc-4689-ac83-111371b838a5_1024x1008.png&quot;,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="" srcset="/__u/substackcdn.com/image/fetch/$s_!c95f!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fa84f5522-cd95-4c47-a41d-b26f4bd5adad_1024x898.png 424w, /__u/substackcdn.com/image/fetch/$s_!c95f!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fa84f5522-cd95-4c47-a41d-b26f4bd5adad_1024x898.png 848w, /__u/substackcdn.com/image/fetch/$s_!c95f!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fa84f5522-cd95-4c47-a41d-b26f4bd5adad_1024x898.png 1272w, /__u/substackcdn.com/image/fetch/$s_!c95f!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fa84f5522-cd95-4c47-a41d-b26f4bd5adad_1024x898.png 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption"><em>This is the <strong>good </strong>reset, to a true, post-scarcity society.</em></figcaption></figure></div><p></p><p>With this simple measure, we dodge every single economic fallacy that has afflicted the welfare states and the socialist utopias, and we maintain true societal and economic stability during that transition. The concept of UBI presumes that the government knows exactly how much economic surplus is being produced, in which sectors that are in demand, where that <em>new</em> demand is going to go, and that the government can walk that tightrope. They cannot. Only the free market can.</p><p>Here, they do not need to. The transition does not need to be centrally planned or managed. We do not need a new currency, or a sudden shift to handing out free UBI to everybody, or even new taxes, incentives or programs. The economy is a machine of pure chaos, and try as they might, the central planners have <em>always</em> created disaster when they intervene. We are already a capitalist land; while it&#8217;s certainly not perfect, capital and labor are already very efficiently allocated across these economies. The business owners and boards know what they need; they know how to produce their products or services, how to turn a profit, and how to keep those goods and services coming. When they decide that a machine can do it better, at a lower cost, and with the same quality, they will probably be right - and they are the only ones that can or should be able to make those decisions. If they make a bad call, they will suffer for it. Capitalist incentive structures remain completely and totally intact. Moral hazard is no more present here than it is anywhere else: the incentive to automate grows, and instead of fearing the loss of one&#8217;s job to automation, people should, by and large, <em>look forward to it, and help to make it so</em>.</p><p></p><h3>THE DOWNSIDE</h3><p>The flip side of this, of course, is that the same people who have suffered the boot of society since time immemorial -<em> the essential workers</em> - are going to continue to suffer. The lowest-paid jobs, in the lowest-margin industries - the proverbial shelf stackers at the grocery stores - will be the very last to be replaced. The capital expenditure for robots and AI, while eventually approaching zero as true automation accelerates, will not hit zero for a long time yet, and for those industries, despite its making long-term economic sense, they will only slowly end up with the capital to buy those systems.</p><p>The downside of this approach - a free market, capitalistic transition to post-scarcity - is that, for a time, we are going to have a bifurcated society. On one hand, you will have the beautiful people; laid off due to automation, their working days are over, and they can live their lives however they like, consuming as they like. On the other hand, are the people still working to serve them: to stack the shelves, to head on home at 9pm, for a mac and cheese dinner, an hour of TV, and a 6am morning start the next day: so that the beautiful people can buy the pork roast that she put on that shelf, and spend their relaxing evenings with their 2.5 children making beautiful meals out of it.</p><p></p><p>It won&#8217;t be fair.</p><p></p><p>Not at first.</p><p></p><p>However, it&#8217;s nothing we haven&#8217;t already seen and lived with. It got a glaring spotlight during the pandemic; but we&#8217;ve always had the trust fund kids, the daddy&#8217;s girls, that guy that got lucky (sorry, it was definitely skill, what a legend) on crypto or the stock market, or the retired boomer that worked all his life and is now comfortably retired. Regardless of one&#8217;s perspective on whether any, all, or none of those people <em>earned</em> their comfort, the bottom-line remains the same - the people that consume without producing. We&#8217;ve seen them, we&#8217;ve lived with them. Society hasn&#8217;t crumbled yet.</p><p></p><p>And it is a temporary state. The adoption curve is, especially in light of both the SMR success and the Genesis Mission, going to be a hockey stick: now you see it, now it&#8217;s accelerating (you are here), and now it&#8217;s everything. As every industry, every business and every executive, one office or boardroom at a time, figures out that they no longer need half, or two thirds, or <em>any</em> of their staff, they will deploy the robots and the AI tools; economic output, the production of our innumerably diverse goods and services, in the millions of different niches, across the unfathomable expanse of our hundreds of millions of people, they will, one-by-one, automate their outputs, and they will reap the extraordinary benefits of it.</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!nuKB!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Feb355893-d350-4d07-b7a0-d6bb653d4cfb_748x586.png" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!nuKB!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Feb355893-d350-4d07-b7a0-d6bb653d4cfb_748x586.png 424w, /__u/substackcdn.com/image/fetch/$s_!nuKB!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Feb355893-d350-4d07-b7a0-d6bb653d4cfb_748x586.png 848w, /__u/substackcdn.com/image/fetch/$s_!nuKB!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Feb355893-d350-4d07-b7a0-d6bb653d4cfb_748x586.png 1272w, /__u/substackcdn.com/image/fetch/$s_!nuKB!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Feb355893-d350-4d07-b7a0-d6bb653d4cfb_748x586.png 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!nuKB!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Feb355893-d350-4d07-b7a0-d6bb653d4cfb_748x586.png" width="312" height="244.42780748663102" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/eb355893-d350-4d07-b7a0-d6bb653d4cfb_748x586.png&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:586,&quot;width&quot;:748,&quot;resizeWidth&quot;:312,&quot;bytes&quot;:null,&quot;alt&quot;:&quot;Here is why hockey stick growth is even harder than you thought | by Dave  Rothschild | Medium&quot;,&quot;title&quot;:null,&quot;type&quot;:null,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:null,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="Here is why hockey stick growth is even harder than you thought | by Dave  Rothschild | Medium" title="Here is why hockey stick growth is even harder than you thought | by Dave  Rothschild | Medium" srcset="/__u/substackcdn.com/image/fetch/$s_!nuKB!, 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class="image-caption">The <em>hockey stick</em> adoption model.</figcaption></figure></div><p>This does not compromise the time-tested incentive structure of capitalism. Goods and services still, by some definitions, remain scarce - at least, relatively so - and the fundamental human condition does not change. Business owners, the owners and operators of the robots and the AIs, will still see the profit, and in reward for their good management, still accumulate wealth to themselves, well above and beyond what those newly displaced will be given by default; and yet, with fully automated production lines, and with truly abundant energy, the consumers, not the capital owners, will eventually become the primary drivers of growth. If everybody has discretionary income, and everybody wants to buy Pinkees&#8217; sandwiches, Pinkee can turn up the dial, produce more sandwiches, and Pinkee makes more money in meeting that demand. True post-scarcity, between automation and energy, is truly a paradigm shift; properly executed, left to the free market, we can still have the best of all worlds.</p><p>The incentive structure, the potential, the drive for growth and accumulation, or for bettering oneself in general, remains intact, and we gradually enter a world where productivity is no longer driven by fear of deprivation, but by genuine desire for one&#8217;s own growth, whatsoever that might look like. The people that would do nothing, the people that would, if not for their need, spend all day on the couch, will not be able to do so at large, or, at least, at first; with a life already led for a bare-minimum avoidance of poverty, the people working those low-value jobs will not yet have been automated; until the machines come for them, their functions in society will continue to be met. Every single person continues on in this world, until the time that their labors are no longer needed. Then, and only then, will they join the ranks of the beautiful people, and if they want to sit on the couch all day, then that is what they will do. No harm, no foul.</p><p></p><h3>THE POLICY</h3><p>The implementation of this is relatively straightforward. Mirroring the design of the pandemic unemployment insurance, but conditioned on automation-related loss of a job or a small business, rather than pandemic-related; with a generous, presumptively granted benefit, to last for the remainder of one&#8217;s natural life, those people displaced, as they join the ranks, will finally be able to truly join the world in The Future, and as the months and years go by, we will make the peaceful, productive transition into a truly post-scarcity society. Capitalism, in all its glory, remains fully intact: with the death of trickle-down economics, in a world where production is a matter of another robot, another AI deployment, or another reactor, consumer demand primarily drives production and growth; the people who own, manage, and invest in the means of production retain them, and profit without bound; the benefits of automation, scaling exponentially under its own power, become fully available to all, and this transition, in which we already find ourselves, and as it presently savages the people, suffering as their jobs are automated away, becomes a celebration instead, and a final, historic unshackling of every man, woman and child in this great nation.</p><p></p><p>It&#8217;s that or the Great Reset.</p><p></p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://veryvirology.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">To receive new articles and support this work, please consider becoming a free or paid subscriber. It makes a difference!</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div><p></p><div><hr></div><p><em>118TH CONGRESS</em></p><p><em>1ST SESSION</em></p><p><em>H. R. ____</em></p><p></p><p>To provide transition assistance to workers and small businesses</p><p>displaced by automation and artificial intelligence, to facilitate an orderly and</p><p>market-driven transition toward a high-automation, high-abundance economy, and</p><p>for other purposes.</p><p>IN THE HOUSE OF REPRESENTATIVES</p><p>[date]</p><p>Mr./Ms. [Sponsor] introduced the following bill; which was referred to the Committee on</p><p>Ways and Means, and in addition to the Committees on Education and the Workforce,</p><p>Financial Services, and Small Business, for a period to be subsequently determined</p><p>by the Speaker, in each case for consideration of such provisions as fall within the</p><p>jurisdiction of the committee concerned</p><p><strong>A BILL</strong></p><p>To establish a national program of Guaranteed Earnings and New Employment Support in response to Intelligent Systems, and for other purposes.</p><p>Be it enacted by the Senate and House of Representatives of the United States of America in Congress assembled,</p><p>SECTION 1. SHORT TITLE; TABLE OF CONTENTS.</p><p>(a) Short Title.&#8212;This Act may be cited as the &#8220;Guaranteed Earnings and New Employment Support in response to Intelligent Systems (<strong>GENESIS</strong>) Act of 2026&#8221;.</p><p>(b) TABLE OF CONTENTS.&#8212;The table of contents for this Act is as follows:</p><p>Sec. 1. Short title; table of contents.</p><p>Sec. 2. Findings; purposes.</p><p>TITLE I&#8212;AUTOMATION DISPLACEMENT INCOME BENEFIT (ADIB)</p><p>Sec. 101. Definitions.</p><p>Sec. 102. Federal-State agreements; establishment of Automation Displacement Income Benefit.</p><p>Sec. 103. Benefit amount and duration.</p><p>Sec. 104. Coordination with other unemployment compensation.</p><p>Sec. 105. Treatment of subsequent employment; non-duplication of benefits.</p><p>Sec. 106. Program integrity; verification; recovery of overpayments.</p><p>Sec. 107. Funding; administrative grants to States.</p><p>TITLE II&#8212;AUTOMATION DISPLACEMENT BUSINESS ASSISTANCE (ADBA)</p><p>Sec. 201. Automation Displacement Business Assistance program.</p><p>Sec. 202. Loan terms; forgiveness; interaction with the Small Business Act.</p><p>Sec. 203. Documentation, self-certification, and oversight.</p><p>TITLE III&#8212;GENERAL PROVISIONS</p><p>Sec. 301. Regulations.</p><p>Sec. 302. GAO reports and evaluations.</p><p>Sec. 303. Sunset; continuation of benefits in pay status.</p><p>Sec. 304. Severability.</p><p>SEC. 2. FINDINGS; PURPOSES.</p><p>(a) FINDINGS.&#8212;Congress finds the following:</p><p>  (1) Rapid advances in automation, robotics, and artificial intelligence are</p><p>  substantially increasing productivity and the supply of goods and services,</p><p>  while reducing the quantity of human labor required across many sectors.</p><p>  (2) Historically, technological change has displaced some workers while</p><p>  creating other opportunities, but current and projected advances in general-</p><p>  purpose AI systems and robotic platforms pose the prospect that net labor</p><p>  demand for many occupations will decline persistently rather than cyclically.</p><p>  (3) The Coronavirus Aid, Relief, and Economic Security Act (Public Law 116&#8211;136)</p><p>  established temporary programs, including Pandemic Unemployment Assistance and</p><p>  the Paycheck Protection Program, which demonstrated that&#8212;</p><p>      (A) self-employed individuals, independent contractors, and owners of very</p><p>      small firms can be reached efficiently through Federal-State partnerships;</p><p>      and</p><p>      (B) rapid deployment of income support and business backstops can avert</p><p>      immediate collapse of household demand and small business balance sheets</p><p>      in the face of sudden economic shocks.</p><p>  (4) Unlike a transitory shock, automation-driven displacement is expected to be</p><p>  ongoing and uneven across sectors, firms, and regions, such that individuals</p><p>  and businesses will face idiosyncratic and permanent losses of livelihoods.</p><p>  (5) Simply distributing unconditional payments to all individuals, without</p><p>  regard to the level and composition of productive output, risks repeating</p><p>  historical failures of centrally-planned welfare schemes, including</p><p>  misalignment between income and real output, inflationary pressures, and the</p><p>  erosion of work and investment incentives.</p><p>  (6) A targeted, generous, and presumptively granted income benefit, triggered</p><p>  by verified automation displacement of labor or business activity, can&#8212;</p><p>      (A) preserve household security and aggregate demand;</p><p>      (B) honor the contribution of displaced workers and entrepreneurs whose</p><p>      efforts helped build the automated productive base;</p><p>      (C) allow firms to adopt efficiency-enhancing automation when economically</p><p>      justified, without fear of catastrophic household-level fallout; and</p><p>      (D) maintain and even strengthen market-based capital allocation and</p><p>      entrepreneurial incentives.</p><p>(b) PURPOSES.&#8212;The purposes of this Act are&#8212;</p><p>  (1) to establish a permanent Federal framework for income support to workers</p><p>  and owners of small enterprises whose jobs or businesses are displaced by</p><p>  automation or artificial intelligence;</p><p>  (2) to structure such support as an entitlement triggered by micro-level</p><p>  displacement decisions made by private employers and customers, rather than</p><p>  by central planners;</p><p>  (3) to permit recipients of automation displacement benefits to engage in new</p><p>  employment or entrepreneurial activity without loss of the baseline benefit,</p><p>  while preventing duplication of displacement claims;</p><p>  (4) to provide small businesses with access to interim financing and partial</p><p>  forgiveness in connection with automation investments and associated workforce</p><p>  transitions; and</p><p>  (5) to facilitate an orderly, capitalist transition toward a high-automation,</p><p>  high-abundance economy, while minimizing involuntary deprivation and</p><p>  preventing concentration of productive gains solely among existing owners of</p><p>  capital.</p><p>TITLE I&#8212;AUTOMATION DISPLACEMENT INCOME BENEFIT (ADIB)</p><p>SEC. 101. DEFINITIONS.</p><p>In this title:</p><p>  (1) SECRETARY.&#8212;The term &#8220;Secretary&#8221; means the Secretary of Labor.</p><p>  (2) STATE.&#8212;The term &#8220;State&#8221; has the meaning given such term in section 205 of</p><p>  the Federal-State Extended Unemployment Compensation Act of 1970 (26 U.S.C.</p><p>  3304 note), and includes, where applicable, the District of Columbia,</p><p>  Puerto Rico, and the Virgin Islands.</p><p>  (3) REGULAR COMPENSATION; UNEMPLOYMENT COMPENSATION.&#8212;The terms &#8220;regular</p><p>  compensation&#8221; and &#8220;unemployment compensation&#8221; have the meanings given such</p><p>  terms in section 205 of the Federal-State Extended Unemployment Compensation</p><p>  Act of 1970.</p><p>  (4) COVERED AUTOMATION EVENT.&#8212;The term &#8220;covered automation event&#8221; means&#8212;</p><p>      (A) a permanent reduction in the number of employees performing one or</p><p>      more functions of a firm, establishment, or division, where at least a</p><p>      substantial portion of such functions has been replaced or materially</p><p>      reduced by the deployment of automated systems, robotics, or artificial</p><p>      intelligence;</p><p>      (B) a permanent and substantial reduction in gross receipts or billable</p><p>      work of a self-employed individual or small business, attributable in</p><p>      significant part to customers substituting automated systems, robotics,</p><p>      or artificial intelligence for goods or services previously provided by</p><p>      such individual or business; or</p><p>      (C) such other events as the Secretary may by regulation specify,</p><p>      consistent with subparagraphs (A) and (B).</p><p>  (5) COVERED INDIVIDUAL.&#8212;The term &#8220;covered individual&#8221; means an individual who&#8212;</p><p>      (A) is unemployed, partially unemployed, or has experienced the permanent</p><p>      cessation of self-employment or small business activity, as a direct or</p><p>      substantial indirect result of a covered automation event; and</p><p>      (B) self-certifies, in good faith and under penalty of perjury, to the</p><p>      conditions in subparagraph (A), and provides such documentation as may be</p><p>      reasonably requested pursuant to section 106.</p><p>  (6) BASELINE DISPLACEMENT ENTITLEMENT.&#8212;The term &#8220;baseline displacement</p><p>  entitlement&#8221; means the ongoing weekly benefit amount determined pursuant to</p><p>  section 103, payable to a covered individual upon a first determination of</p><p>  automation displacement, and continuing under section 105.</p><p>  (7) SMALL BUSINESS; SMALL ENTITY.&#8212;The terms &#8220;small business&#8221; and &#8220;small</p><p>  entity&#8221; have the meanings given the terms &#8220;small business concern&#8221; and</p><p>  &#8220;small entity&#8221; in section 3 of the Small Business Act (15 U.S.C. 632), and</p><p>  applicable regulations of the Small Business Administration.</p><p>SEC. 102. FEDERAL-STATE AGREEMENTS; ESTABLISHMENT OF AUTOMATION DISPLACEMENT</p><p>INCOME BENEFIT.</p><p>(a) IN GENERAL.&#8212;Subject to subsection (c), the Secretary shall enter into an</p><p>agreement with any State which desires to participate in the program established</p><p>by this title for the payment of Automation Displacement Income Benefits</p><p>(&#8220;ADIB&#8221;) to covered individuals.</p><p>(b) PROVISIONS OF AGREEMENT.&#8212;Any agreement under subsection (a) shall provide</p><p>that the State agency that administers the State&#8217;s unemployment compensation</p><p>law will&#8212;</p><p>  (1) accept applications for ADIB from individuals located in such State, and</p><p>  permit application and self-certification by electronic means;</p><p>  (2) make initial determinations of eligibility based on self-certification</p><p>  under section 101(5), with a presumption in favor of eligibility, subject to</p><p>  subsequent verification under section 106;</p><p>  (3) pay ADIB to covered individuals in accordance with section 103; and</p><p>  (4) comply with such reporting, auditing, and program integrity requirements</p><p>  as the Secretary may establish, consistent with this title.</p><p>(c) EFFECTIVE DATE.&#8212;An agreement under this section shall take effect on the</p><p>first day of the first week beginning after the date on which such agreement is</p><p>entered into, or such later date as may be provided in such agreement.</p><p>(d) APPLICATION TO INDIVIDUALS NOT ENTITLED TO REGULAR COMPENSATION.&#8212;ADIB under</p><p>this title shall be payable to covered individuals regardless of whether such</p><p>individuals are eligible for regular compensation or any other unemployment</p><p>compensation under State or Federal law.</p><p>SEC. 103. BENEFIT AMOUNT AND DURATION.</p><p>(a) WEEKLY BENEFIT AMOUNT.&#8212;</p><p>  (1) IN GENERAL.&#8212;Subject to paragraph (2), the weekly amount of ADIB payable to</p><p>  a covered individual for any week shall be equal to&#8212;</p><p>      (A) the weekly benefit amount that would be payable to such individual</p><p>      under the unemployment compensation law of the State of residence if such</p><p>      individual were otherwise eligible for regular compensation, including any</p><p>      dependents&#8217; allowances; or</p><p>      (B) in the case of an individual who would not otherwise qualify for</p><p>      regular compensation under State law, an amount determined under</p><p>      regulations of the Secretary, which shall approximate the individual&#8217;s</p><p>      average weekly earnings from the employment, self-employment, or business</p><p>      activity displaced by the covered automation event, subject to a State</p><p>      maximum.</p><p>  (2) MINIMUM AND MAXIMUM.&#8212;The Secretary may by regulation establish national</p><p>  minimum and maximum ADIB weekly benefit amounts, taking into consideration</p><p>  prevailing wage levels, cost of living, and fiscal sustainability.</p><p>(b) DURATION.&#8212;</p><p>  (1) BASELINE ENTITLEMENT.&#8212;A covered individual&#8217;s baseline displacement</p><p>  entitlement shall be payable for as long as such individual&#8212;</p><p>      (A) remains alive; and</p><p>      (B) has not been determined, under procedures established by the</p><p>      Secretary, to have intentionally misrepresented material facts in</p><p>      obtaining the benefit.</p><p>  (2) NO REQUIREMENT OF CONTINUED UNEMPLOYMENT.&#8212;Eligibility for ADIB shall not</p><p>  be conditioned on continued unemployment, active work search, or non-receipt</p><p>  of wage income, except as provided in section 105(b) with respect to</p><p>  non-duplication of displacement determinations.</p><p>(c) LUMP SUM TRANSITION PAYMENTS.&#8212;The Secretary may, by regulation and with</p><p>State consent, permit a covered individual to elect to convert a portion of</p><p>future ADIB into a one-time or time-limited higher payment for the purpose of</p><p>relocation, education, or business formation.</p><p>SEC. 104. COORDINATION WITH OTHER UNEMPLOYMENT COMPENSATION.</p><p>(a) NO REDUCTION OF REGULAR COMPENSATION.&#8212;Receipt of ADIB shall not reduce the</p><p>amount of any regular compensation, extended compensation, or other unemployment</p><p>compensation payable to an individual under any State or Federal law, nor shall</p><p>such other compensation reduce the individual&#8217;s baseline displacement</p><p>entitlement under this title.</p><p>(b) ELECTION OF BENEFITS DURING PERIODS OF UNEMPLOYMENT.&#8212;During any week for</p><p>which an individual is eligible for regular compensation and ADIB, the State</p><p>may, consistent with Federal regulations, require the individual to elect which</p><p>benefit shall constitute the primary benefit for that week; but in no case</p><p>shall such election terminate or diminish the individual&#8217;s baseline displacement</p><p>entitlement.</p><p>(c) TREATMENT FOR TAX PURPOSES.&#8212;ADIB shall be treated for purposes of the</p><p>Internal Revenue Code of 1986 in a manner similar to unemployment compensation,</p><p>except as otherwise provided by Congress.</p><p>SEC. 105. TREATMENT OF SUBSEQUENT EMPLOYMENT; NON-DUPLICATION OF BENEFITS.</p><p>(a) CONTINUED ENTITLEMENT NOTWITHSTANDING EMPLOYMENT.&#8212;</p><p>  (1) IN GENERAL.&#8212;A covered individual shall remain entitled to receive ADIB</p><p>  notwithstanding subsequent employment, self-employment, or business activity,</p><p>  and such employment or activity shall not, by itself, constitute grounds for</p><p>  reduction, suspension, or termination of the baseline displacement</p><p>  entitlement.</p><p>  (2) EARNED INCOME.&#8212;States shall not impose earnings offsets or work-search</p><p>  requirements with respect to ADIB, except as may be necessary to administer</p><p>  taxation or garnishment under Federal law.</p><p>(b) NON-DUPLICATION OF DISPLACEMENT ENTITLEMENTS.&#8212;</p><p>  (1) SINGLE BASELINE ENTITLEMENT.&#8212;An individual may have only one baseline</p><p>  displacement entitlement in effect at any time.</p><p>  (2) ADDITIONAL AUTOMATION EVENTS.&#8212;In the case of a covered individual who</p><p>  experiences additional covered automation events after an initial ADIB</p><p>  determination, the Secretary shall by regulation&#8212;</p><p>      (A) permit adjustment of the weekly benefit amount where the later</p><p>      displacement reflects a substantially higher prior earnings level; and</p><p>      (B) prevent duplicative or stacked baseline entitlements.</p><p>SEC. 106. PROGRAM INTEGRITY; VERIFICATION; RECOVERY OF OVERPAYMENTS.</p><p>(a) PRESUMPTIVE APPROVAL; BE GENEROUS STANDARD.&#8212;</p><p>  (1) INITIAL DETERMINATIONS.&#8212;States shall approve ADIB applications on the</p><p>  basis of self-certification under section 101(5), absent clear evidence of</p><p>  ineligibility.</p><p>  (2) GOOD-FAITH STANDARD.&#8212;In evaluating self-certifications, State agencies</p><p>  shall apply a presumption of good faith and shall not deny benefits solely on</p><p>  the basis of incomplete documentation where the facts asserted are reasonably</p><p>  consistent with available information.</p><p>(b) VERIFICATION.&#8212;</p><p>  (1) IN GENERAL.&#8212;State agencies shall, on a statistically valid sample basis</p><p>  and in targeted cases involving indications of fraud, request additional</p><p>  documentation from employers, platforms, or tax records, or employ automated</p><p>  data-matching tools, to verify the occurrence of a covered automation event</p><p>  and prior earnings.</p><p>  (2) AUTOMATED TOOLS.&#8212;The Secretary is authorized to develop or procure</p><p>  automated verification tools and to make such tools available to States.</p><p>(c) OVERPAYMENTS.&#8212;</p><p>  (1) IN GENERAL.&#8212;In the case of an overpayment of ADIB to an individual, the</p><p>  State shall, except as provided in paragraph (2), require such individual to</p><p>  repay the amount of such overpayment, under terms that do not impose undue</p><p>  hardship.</p><p>  (2) WAIVER.&#8212;The State may waive repayment where the overpayment was without</p><p>  fault on the part of the individual and recovery would be contrary to equity</p><p>  and good conscience.</p><p>(d) FRAUD.&#8212;Any individual who, by reason of knowingly false statement or</p><p>misrepresentation of a material fact, or by reason of a willful failure to</p><p>disclose a material fact, obtains or increases an ADIB payment shall be subject</p><p>to disqualification and penalties under applicable State and Federal law,</p><p>including criminal penalties.</p><p>SEC. 107. FUNDING; ADMINISTRATIVE GRANTS TO STATES.</p><p>(a) FUNDING.&#8212;There are authorized to be appropriated such sums as may be</p><p>necessary to carry out this title, including the payment of ADIB and grants to</p><p>States for administration.</p><p>(b) ADMINISTRATIVE COSTS.&#8212;The Secretary shall pay to each State with which an</p><p>agreement under section 102 is in effect an amount equal to 100 percent of</p><p>necessary additional administrative costs, as determined by the Secretary.</p><p>(c) TRUST FUND.&#8212;Amounts appropriated to carry out this title shall be</p><p>transferred from the general fund of the Treasury to the Federal unemployment</p><p>account in the Unemployment Trust Fund, or to such separate account as the</p><p>Secretary of the Treasury may establish, and shall remain available until</p><p>expended.</p><p>TITLE II&#8212;AUTOMATION DISPLACEMENT BUSINESS ASSISTANCE (ADBA)</p><p>SEC. 201. AUTOMATION DISPLACEMENT BUSINESS ASSISTANCE PROGRAM.</p><p>(a) IN GENERAL.&#8212;The Small Business Act (15 U.S.C. 631 et seq.) is amended by</p><p>inserting after section 7(a)(37) the following:</p><p>  &#8220;(38) AUTOMATION DISPLACEMENT BUSINESS ASSISTANCE.&#8212;</p><p>    &#8220;(A) IN GENERAL.&#8212;During the period beginning on the date of enactment of</p><p>    the Automation Displacement Transition and Stability Act of 20__ and</p><p>    ending on a date determined by the Administrator, the Administration may</p><p>    guarantee covered loans under this paragraph to small business concerns</p><p>    that&#8212;</p><p>        &#8220;(i) have experienced, or reasonably anticipate, a covered automation</p><p>        event (as defined in section 101 of such Act) that displaces 1 or more</p><p>        employees or materially reduces the business&#8217;s revenue from a line of</p><p>        activity; and</p><p>        &#8220;(ii) commit to use the proceeds of such loans for one or more of the</p><p>        following:</p><p>            &#8220;(I) Capital expenditures for automation, robotics, or artificial</p><p>            intelligence systems that increase productivity.</p><p>            &#8220;(II) Transition assistance for affected workers, including but not</p><p>            limited to severance, retraining, relocation assistance, or</p><p>            supplementing ADIB payments.</p><p>            &#8220;(III) Reconfiguration of business models toward new lines of</p><p>            activity not yet fully automated.</p><p>    &#8220;(B) MAXIMUM LOAN AMOUNT.&#8212;The maximum amount of a covered loan under this</p><p>    paragraph shall be determined by the Administrator, but shall not exceed a</p><p>    multiple of the borrower&#8217;s average total monthly payroll or net earnings,</p><p>    as specified by regulation.</p><p>    &#8220;(C) TERMS; INTEREST.&#8212;Covered loans under this paragraph shall have such</p><p>    terms, including interest rates, maturities, and deferral periods, as the</p><p>    Administrator may prescribe, consistent with the objectives of the</p><p>    Automation Displacement Transition and Stability Act of 20__.</p><p>    &#8220;(D) PARTIAL FORGIVENESS.&#8212;A portion of the principal amount of a covered</p><p>    loan under this paragraph may be forgiven, in an amount not to exceed a</p><p>    percentage specified by the Administrator, if the borrower&#8212;</p><p>        &#8220;(i) demonstrates that the borrower implemented the automation or AI</p><p>        investments specified in subparagraph (A)(ii)(I); and</p><p>        &#8220;(ii) demonstrates that the borrower provided specified levels of</p><p>        support to affected workers, including but not limited to supplementing</p><p>        ADIB, retraining, or placement assistance.&#8221;.</p><p>(b) REGULATIONS.&#8212;The Administrator of the Small Business Administration shall,</p><p>not later than 180 days after the date of enactment of this Act, promulgate</p><p>interim final regulations to carry out this section.</p><p>SEC. 202. LOAN TERMS; FORGIVENESS; INTERACTION WITH THE SMALL BUSINESS ACT.</p><p>(a) APPLICATION OF EXISTING FRAMEWORK.&#8212;Except as otherwise provided in this</p><p>title, loans made under section 7(a)(38) of the Small Business Act shall be</p><p>subject to the same terms, conditions, and procedures as loans made under</p><p>section 7(a) generally.</p><p>(b) PROHIBITION ON DOUBLE BENEFIT.&#8212;No recipient of a loan under section 7(a)(38)</p><p>may receive forgiveness under such section with respect to expenses that are</p><p>also used to obtain forgiveness or credits under any other Federal program, as</p><p>determined by the Administrator and the Secretary of the Treasury.</p><p>SEC. 203. DOCUMENTATION, SELF-CERTIFICATION, AND OVERSIGHT.</p><p>(a) SELF-CERTIFICATION.&#8212;Applicants for loans under section 7(a)(38) of the</p><p>Small Business Act may self-certify, in good faith, that they meet the criteria</p><p>in section 201(a), subject to subsequent verification through tax records,</p><p>payroll records, or other documentation.</p><p>(b) OVERSIGHT.&#8212;The Administrator shall coordinate with the Inspector General of</p><p>the Small Business Administration and the Comptroller General of the United</p><p>States to conduct oversight, audits, and investigations of loans made and</p><p>forgiven under this title.</p><p>TITLE III&#8212;GENERAL PROVISIONS</p><p>SEC. 301. REGULATIONS.</p><p>The Secretary of Labor, the Secretary of the Treasury, and the Administrator of</p><p>the Small Business Administration shall each prescribe such regulations, and</p><p>issue such guidance, as may be necessary to carry out this Act, including&#8212;</p><p>  (1) detailed criteria for identifying covered automation events;</p><p>  (2) standardized self-certification forms; and</p><p>  (3) coordinated data-sharing protocols for verification and oversight.</p><p>SEC. 302. GAO REPORTS AND EVALUATIONS.</p><p>The Comptroller General of the United States shall&#8212;</p><p>  (1) not later than 3 years after the date of enactment of this Act, submit to</p><p>  Congress an initial report evaluating the implementation and economic effects</p><p>  of this Act; and</p><p>  (2) at 5-year intervals thereafter, submit updated evaluations, including</p><p>  recommendations for legislative or administrative changes.</p><p>SEC. 303. SUNSET; CONTINUATION OF BENEFITS IN PAY STATUS.</p><p>(a) SUNSET OF NEW DETERMINATIONS.&#8212;No new ADIB determinations or ADBA loans may</p><p>be made after the date that is 25 years after the date of enactment of this</p><p>Act, unless reauthorized by Congress.</p><p>(b) CONTINUATION OF EXISTING BENEFITS.&#8212;Nothing in subsection (a) shall be</p><p>construed to terminate or reduce baseline displacement entitlements already in</p><p>pay status, or to impair any rights or obligations under loans made before such</p><p>date.</p><p>SEC. 304. SEVERABILITY.</p><p>If any provision of this Act, or the application of such provision to any person</p><p>or circumstance, is held to be unconstitutional, the remainder of this Act, and</p><p>the application of the provisions of such to any person or circumstance, shall</p><p>not be affected.</p>]]></content:encoded></item><item><title><![CDATA[The Universal Antiviral Protocol]]></title><description><![CDATA[Suffer not a cold to live.]]></description><link>https://veryvirology.substack.com/p/the-universal-antiviral-protocol</link><guid isPermaLink="false">https://veryvirology.substack.com/p/the-universal-antiviral-protocol</guid><dc:creator><![CDATA[Adam Gaertner]]></dc:creator><pubDate>Thu, 04 Dec 2025 01:09:29 GMT</pubDate><enclosure url="https://substack-post-media.s3.amazonaws.com/public/images/ee05a95c-1f7c-4494-912b-0f5f79b55b16_1536x1024.png" length="0" type="image/jpeg"/><content:encoded><![CDATA[<p>It occurred to me, that since we succeeded in making ivermectin a household name, from &#8216;21 onward, I haven&#8217;t actually published the full antiviral protocol that started it all, in quite some time; and in any case, all the places that I had published it - censored from <a href="https://x.com/verycosmic/status/1238287228360507392 Now">Medium</a>, censored from <a href="https://x.com/veryvirology/status/1450259175729090560?s=20">Patreon</a>, offline on my own .com that was <a href="https://x.com/verycosmic/status/1268378917842202624">seized</a> by the registrars for &#8216;misinformation&#8217; (!!), and <a href="https://www.scribd.com/document/487305323/Gaertner-Protocol">drafted study designs</a> that I never published at all - they are all, presently, unavailable, save for <a href="https://x.com/veryvirology/status/1266065638511931397?s=20">scattered</a> <a href="https://x.com/veryvirology/status/1256315735858483200?s=20">old</a> <a href="https://x.com/veryvirology/status/1249197924384477185?s=20">tweets</a> buried in the annals of history.</p><p>So, I&#8217;m going to remedy that.</p><p>This is, for anybody with an even remotely functional immune system, the first, last and only early-stage ssRNA antiviral protocol you&#8217;ll ever need. It hasn&#8217;t changed a bit since 2020 - with the possible exception of higher IVM dosage in some cases - and I have not suffered from a viral infection, for the last six years and counting, for more than a few hours. Colds, influenza, even extended and heavy Hantavirus exposure as we were in the process of making this house a home; you name it. It sure was nice to be able to work on that project with the absolute confidence that it wasn&#8217;t going to give me so much as a sniffle, much less kill me, and it didn&#8217;t. With an understanding of how a viral infection actually makes you feel &#8220;sick&#8221; - what that even is, and how much of it is the action of the viral agent itself, versus your own immune system making you feel miserable - and by taking advantage of the synergistic effects of several universally available, cheap therapeutics, one can have complete, total control over any viral ssRNA illness. That caveat is important: it&#8217;s not going to do anything for eg. a herpes zoster infection, which is DNA based, for reasons that will become clear as we walk through how and why this protocol works, and works so very quickly; but <em>any</em> ssRNA virus, from a coronavirus or norovirus, to an early-stage Ebola infection - with the numerous, deleterious immunomodulatory effects of an ebolavirus infection, as with any of the viral illnesses we&#8217;ll cover here, a mid- or late- stage infection is a <a href="https://www.pnas.org/doi/10.1073/pnas.1502619112">completely different beast</a> - but otherwise, they can, all, be promptly and almost immediately cured, <em>when caught early</em>, with this method.</p><p>I <a href="https://www.youtube.com/watch?v=RDzBdDhyJzI Now">told Dr. Mobeen</a>, in 2020, that the effects and mechanisms of ivermectin that we&#8217;d discovered, insofar as antiviral actions, warranted calling it &#8220;a new penicillin for viruses.&#8221; Six years, and a veritable mountain of published studies later, that has borne out in spades. The ascorbic acid component of the protocol was, by and large, lost in the shuffle; as the controlled opposition took over, managing the unstoppable wave of awareness of ivermectin, and politicizing it, to still limit its impact as best they could, all eyes were over there; trusted &#8220;influencers&#8221; covered it up and, admittedly, lied, about the equally critical other half of this protocol, and now, while ivermectin has become a household name - which, don&#8217;t get me wrong, is still a world-altering development, for those who know better than to derisively call it horse paste - the proper use, form, and power of ascorbic acid, even amongst those practitioners and people who did the research, and braved the heat over ivermectin and its use, has remained largely unknown.</p><p>I think it&#8217;s time to change that. Ivermectin alone is just this side of miraculous, offering a relatively rapid recovery from most viral illness, within a few days at the outer limits when properly dosed; but the near-instantaneous recovery offered by the proper use of ascorbic acid could, conceivably, shake the world to its foundations. Imagine a world where the typical viral illnesses are all but a thing of the past. No more flu season; no more missing days or weeks of school or work because you&#8217;re suffering in bed; the case for masks and vaccines, fraudulent as they are even now, indisputably collapsing into irrelevance across the spectrum; many of the pharma giants, that poisoned so many people, getting their richly deserved bankruptcies, as billions of dollars of investment into boutique, half-measure drugs evaporates; and many of the hospitals, the Covid <a href="https://chbmp.org/">murder-for-hire factories</a> at <a href="https://www.kgns.tv/2022/03/28/government-pays-hospitals-more-money-covid-19-patients-than-non-covid-patients/">$40k per innocent life</a>, who generally derive a large portion of their annual revenue from the cold and flu seasons, seeing similarly well-earned collapses. Up to 650 billion healthy hours of life are lost, every year, just to respiratory viral illness alone. If you care about the GDP, that&#8217;s a 3-6% annualized jump, practically overnight. We can have that time back.</p><p>Without further ado, let&#8217;s walk through the protocol, why each component is such a revolution in treatment of viral infection, the proper forms in which they need to be used, and the immunological and microbiological explanations of how they work.</p><p></p><h3>The Protocol</h3><p>Ask your doctor if it&#8217;s right for you:</p><ul><li><p>150 micrograms per kilogram of body weight oral ivermectin, once per day, with fatty food or drink for optimal absorption</p></li><li><p>55 milligrams per kilogram of body weight unsugared, pure, 80+ mesh ascorbic acid powder (vitamin C), per three hours, with an optional, one-time initial 110 milligram per kilogram dose for moderate to severe illness</p><p></p></li></ul><p>In medical Latin, for your doctor&#8217;s consideration:</p><ul><li><p>150mcg/kg ivermectin po qd with food</p></li><li><p>55mg/kg unsugared, pure, 80+ mesh ascorbic acid powder, po q3, optional 110mg/kg bolus for moderate disease, ideally on an empty stomach</p></li></ul><p></p><p>That&#8217;s it! Taken in the early replication phase of any viral ssRNA infection, full symptomatic recovery is counted in seconds to minutes, not hours or days, and actual clearance of the infection - there is a very distinct difference, which quickly becomes notable at that three-hour dosing interval - should occur within a day or two.</p><p></p><h3>The How</h3><p>Ivermectin and ascorbic acid have very different modes of action and administration.</p><p></p><h4>Ivermectin</h4><p><em>For a broad, accessible primer on immunology in general, I covered a lot of the ground floor science in <a href="/__u/veryvirology.substack.com/p/igg4-antibody-class-switch-end-of">this article</a>.</em></p><p>The very first element that lead <a href="https://x.com/verycosmic/status/1240499334736515072">us</a> to ivermectin was its production of <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC5835698/">interferon</a>. Interferon-alpha, the body&#8217;s primary, all-purpose antiviral signaling molecule, has numerous functions. It&#8217;s produced in an infected cell, after the activation of RIG-I/MDA5, to warn other cells in the vicinity that an infection is present. Upon release into the bloodstream,  and subsequent entry to another cell via the IFNAR receptor, the recipient cell both replicates and amplifies the interferon signal, and activates the JAK-STAT pathways. Endosomes, the ordinary means by which most viruses will first be screened for entry into a cell after binding to a receptor, will not always be on high alert; receipt of an interferon signal tells the cell to put the metal detectors and the sheriff at the door, and screening of newly admitted entrants is greatly enhanced with the production of IFITM3 and TLR7, among others, which bind to the endosome and poke through it.</p><p>If one of them binds to the contents, it activates the appropriately corresponding cascade; in the case of a viral infection, viral ssRNA is detected by TLR7, and in the subsequent interferon cascade, numerous defenses in the cell, including OAS and PKR are activated; viral fusion is prohibited, the endosome becomes a lysosome (from Greek, &#8216;to lyse,&#8217; or cut) the endosome is filled with proteins and chemicals that destroy the contents, and the viral entry is defeated before it can release its RNA or cause any harm to the cell. That is also the key to why this is so powerful, but only against ssRNA; DNA viruses require completely different response pathways, and often have much more evolved cloaking mechanisms that are not responsive to those immune defenses targeting ssRNA. Furthermore, infected cells are not, as a matter of course, directly destroyed by this protocol, so while there will be a temporary, useful action against eg. retroviral HIV, it will not serve as a cure in this case; here, it&#8217;s more of a short term reset button for viral load, presuming enough immune function remains for even that to occur.</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!EscD!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fa64bd557-95d7-4db7-85d0-9fbdc3bd1965_996x996.jpeg" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!EscD!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, 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/__u/substackcdn.com/image/fetch/$s_!EscD!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fa64bd557-95d7-4db7-85d0-9fbdc3bd1965_996x996.jpeg 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption">HSV latency cloaking and reactivation. <em>Cliffe, A. R., Arbuckle, J. H., &amp; Vogel, J. L., et al. (2015). Neuronal stress pathway mediating a histone methyl/phospho switch is required for herpes simplex virus reactivation. Cell Host &amp; Microbe, 18(6), 649&#8211;658. <a href="https://doi.org/10.1016/j.chom.2015.11.004">https://doi.org/10.1016/j.chom.2015.11.004</a></em></figcaption></figure></div><p>One of the single most notable actions of ivermectin, notwithstanding all the numerous other immunomodulatory effects it exhibits, is that it induces a <a href="https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0168170">pronounced upregulation of interferon-responsive genes</a> &#8212; ISG20, IFIT1, OASL, IRF9, IFI44, IFIT2 &#8212; causing millions of cells to effectively react as though they&#8217;ve been infected. This is what makes it an excellent prophylactic, to put the body on alert even before any infection has been encountered, and aids enormously in the treatment of an active infection. SARS-CoV-2, along with the vast majority of viral infections that survive long enough to give you a hard time, have numerous immunosuppressive features; suppressing the interferon response of infected cells is the <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC5576560/">ubiquitous</a>, bottom-line, &#8220;duh&#8221; action, without which no viral infection would survive past the first cell it encountered. Ivermectin functionally and completely obviates and obliterates that, already dealing a lethal blow to practically every last ssRNA virus in existence. Our cytosolic immune systems are extremely capable, when they&#8217;re able to act: this enables them to do so. The only meaningful cost is a little more energy being expended to remain on high alert; certainly not a dealbreaker.</p><p>Ivermectin is also a potent anti-inflammatory, <a href="https://pubmed.ncbi.nlm.nih.gov/38636372/">acting</a> to suppress the nF-kB pathway, which helps to mitigate the body&#8217;s natural reactions to infection. Usually, along with fever, they are quite warranted and helpful, but given that most of the unpleasant symptoms of a viral infection are owed to your own immune response, rather than anything a given virus is actually doing, shutting them down is appropriate here. Thanks, but no thanks: we&#8217;re gonna do this our way.</p><p>I could digress into the numerous other actions of ivermectin, across so many different contexts - it is a core component of my <a href="/__u/veryvirology.substack.com/p/curing-the-incurable-cancer">cancer protocol</a>, among many other things - but it would be outside the scope of this article. Those actions, alone amongst all the others, are enough to seal its role as a core component of this protocol. One of these days.</p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://veryvirology.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">To receive new articles and support this work, please consider becoming a free or paid subscriber. It makes a difference!</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div><h4>Ascorbic Acid</h4><p>Ascorbic acid has to be one of the most misunderstood therapeutics in modern history. It&#8217;s very well known to be a general &#8220;immune booster,&#8221; and that&#8217;s about the extent to which most people know or care about it. In truth, used properly, it&#8217;s the nuclear option against viral infection, and whilst not quite so powerful elsewhere, still quite useful against other kinds of disease. It has several different modes of action, and several different methods: different amounts, in different forms, and in different contexts, will do different things; and many of the commonly available formulations seem to be, whether coincidentally or not I don&#8217;t know, specifically formulated to completely avoid its most powerful mode of action.</p><p></p><p>Which is, of course, the one we&#8217;re focusing on here.</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!xK7Z!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F8f48f138-2924-4090-bfb7-e55956f7c76b_1024x1017.png" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!xK7Z!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F8f48f138-2924-4090-bfb7-e55956f7c76b_1024x1017.png 424w, /__u/substackcdn.com/image/fetch/$s_!xK7Z!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F8f48f138-2924-4090-bfb7-e55956f7c76b_1024x1017.png 848w, /__u/substackcdn.com/image/fetch/$s_!xK7Z!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F8f48f138-2924-4090-bfb7-e55956f7c76b_1024x1017.png 1272w, /__u/substackcdn.com/image/fetch/$s_!xK7Z!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F8f48f138-2924-4090-bfb7-e55956f7c76b_1024x1017.png 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!xK7Z!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F8f48f138-2924-4090-bfb7-e55956f7c76b_1024x1017.png" width="296" height="293.9765625" 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/__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F8f48f138-2924-4090-bfb7-e55956f7c76b_1024x1017.png 424w, /__u/substackcdn.com/image/fetch/$s_!xK7Z!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F8f48f138-2924-4090-bfb7-e55956f7c76b_1024x1017.png 848w, /__u/substackcdn.com/image/fetch/$s_!xK7Z!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F8f48f138-2924-4090-bfb7-e55956f7c76b_1024x1017.png 1272w, /__u/substackcdn.com/image/fetch/$s_!xK7Z!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F8f48f138-2924-4090-bfb7-e55956f7c76b_1024x1017.png 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption"><em>Put the Emergen-C down and back away slowly.</em></figcaption></figure></div><p>How often do you see a wild animal with a cold? Not often. At some point in human history, we <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC3145266/">lost</a> the function of the GULO gene, which provided us all the ascorbic acid we could ever need, and a great deal more during the course of an infection. I&#8217;ve long wondered what evolutionary advantage could possibly have been gained from that loss. The leading theory is that there was enough of it in the average proto-human&#8217;s diet, so there was no selective pressure <em>against</em> the random mutation that took it out; maybe the energy saved in not producing it became decisive at some bottleneck in our distant past. Maybe <a href="https://www.science.org/doi/10.1126/science.abq7487">that</a> bottleneck. Maybe it just happened to be a feature of those very few people that survived, and with no need for it, life went on.</p><p>However, after centuries of the arms race between viruses and the human immune system, and in the current era of <a href="https://www.hsgac.senate.gov/media/reps/dr-paul-makes-case-for-lab-leak-at-first-full-senate-committee-hearing-on-covid-19-origins/">lab</a>-<a href="https://x.com/disclosetv/status/1993976106668396830">engineered</a> <a href="https://x.com/TuckerCarlson/status/1788690414738051402">bioweapons</a> freely circulating amongst the unwashed masses, it&#8217;s starting to be missed. Maybe we&#8217;ll get it back. Failing that&#8230; we make do.</p><p></p><h4>Absorption: the missing link</h4><p>The first thing to understand about ascorbic acid is how it&#8217;s absorbed. There&#8217;s two primary methods of administration: oral, through the stomach and GI tract, and IV, directly into the bloodstream. Mainstream medical practice, where it acknowledges it at all, tends to hold that its most powerful effects are only accessible with enormous, intravenous doses.</p><p>They&#8217;re half right.</p><p>In the duodenum and jejunum, AA is first absorbed into the bloodstream <a href="https://pubmed.ncbi.nlm.nih.gov/11895172/">by</a> the SVCT1/2 transporters. There&#8217;s a lot of them, and absorption can be extremely rapid - not quite, but functionally almost as fast as an actual injection - if you want it to be, and if you account for a just a couple of the minor pitfalls that have almost completely locked away its most potent effects.</p><p>The first is easy: surface area. It doesn&#8217;t matter how much you take at once, if all those molecules can&#8217;t reach the transporters in time. I&#8217;ll explain the finer points of dosing soon, but for now, suffice to say that it enters a whole new realm of effect above a certain threshold dose; the instantaneous availability in the blood, of a great number of those ascorbic acid molecules, is central to the most useful effects. When taken in chewable or pill form, it&#8217;s compressed into a tight mass that is only slowly broken down in the stomach and made available to the body. Not to knock its dietary and general immune &#8216;boosting&#8217; functions; it still has its place in that form; but you&#8217;re not going to see the best of it.</p><p>The second is much more insidious: sugar! The gut is an oxidizing - acidic - environment, and the secondary GLUT transporter, which picks up the oxidized form, <em>dehydroascorbic acid,</em> also<em> </em>transports<em> </em>sugars, and <em>preferentially so!</em> &#8220;Sugars&#8221; aren&#8217;t entirely what you might think. We&#8217;re not just talking about refined glucose or powdered sugars; carbohydrates in their totality, bread for example, are in fact sugars, at least insofar as that transporter is concerned, once the stomach is done with them. Carbohydrates are <em>practically ubiquitous</em>:<em> </em>if you have two grams of ascorbic acid in your stomach, and fifty grams of bread, that ascorbic acid is just going to have to wait its turn<em>.</em> That dramatically lowers the instantaneously available dose to cross into the bloodstream.</p><p>In short, if you&#8217;re looking at a Vitamin C supplement, check if there&#8217;s sugars or carbohydrates in it. Those nutrition labels are there for a reason. And if there is - more power to you for the slow, generalized immune boost - but throw it out if you want the best that it has to offer.</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!lQjx!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F43996c12-d1d7-408e-8c72-e19ea27316cc_1280x720.jpeg" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!lQjx!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F43996c12-d1d7-408e-8c72-e19ea27316cc_1280x720.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!lQjx!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F43996c12-d1d7-408e-8c72-e19ea27316cc_1280x720.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!lQjx!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F43996c12-d1d7-408e-8c72-e19ea27316cc_1280x720.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!lQjx!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F43996c12-d1d7-408e-8c72-e19ea27316cc_1280x720.jpeg 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!lQjx!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F43996c12-d1d7-408e-8c72-e19ea27316cc_1280x720.jpeg" width="450" height="253.125" 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/__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F43996c12-d1d7-408e-8c72-e19ea27316cc_1280x720.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!lQjx!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F43996c12-d1d7-408e-8c72-e19ea27316cc_1280x720.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!lQjx!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F43996c12-d1d7-408e-8c72-e19ea27316cc_1280x720.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!lQjx!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F43996c12-d1d7-408e-8c72-e19ea27316cc_1280x720.jpeg 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption"><em>Bread lines like you&#8217;ve never seen them.</em></figcaption></figure></div><p>The next thing to understand is the plethora of actions and uses it has in the body. There&#8217;s so many that it&#8217;s hard to know where to start: it&#8217;s an immunomodulatory anti-inflammatory, an anti-oxidant, a simple chemical acid, and most critically, among many others, it&#8217;s the acidic fuel that your neutrophils run on.</p><p>Neutrophils have several modes of attack. The first, and most useful, is phagocytosis. When you consider the scale of a single virion, versus any given neutrophil, the difference is downright titanic; a virion might as well be gazing up at Godzilla. However, it&#8217;s not just one virion: it&#8217;s millions or billions of them. Healthy neutrophils float around the blood, and if they encounter a virion, they will eat it, and destroy it. That &#8216;destroying&#8217; part consumes ascorbic acid. Once the body realizes it&#8217;s got an infection, which isn&#8217;t instant - generally, that signaling takes a day or two to even reach the lymph nodes and set off the chain reaction - it also sends neutrophil production into overdrive, which further depletes the ambient ascorbic acid available to any given neutrophil. You may be more familiar with them as the gooey white pus occasionally seen in an infection: that&#8217;s a graveyard of millions of your best soldiers, and to end up there, they will, <em>upon running</em> <em>out of fuel</em>, go kamikaze, literally exploding and casting out their DNA as a trap, in a process called <strong><a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC3576733/">NET</a></strong><a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC3576733/">osis</a>. It&#8217;s a neat trick, and an honorable last act, but as you might imagine, it makes an inflammatory mess, and it isn&#8217;t the best use of their faculties.</p><p>If only they had what they needed to carry on!</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!dwVC!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F476e9f2d-2f8e-4f34-9551-83890bc6095e_784x468.jpeg" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!dwVC!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F476e9f2d-2f8e-4f34-9551-83890bc6095e_784x468.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!dwVC!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F476e9f2d-2f8e-4f34-9551-83890bc6095e_784x468.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!dwVC!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F476e9f2d-2f8e-4f34-9551-83890bc6095e_784x468.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!dwVC!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F476e9f2d-2f8e-4f34-9551-83890bc6095e_784x468.jpeg 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!dwVC!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F476e9f2d-2f8e-4f34-9551-83890bc6095e_784x468.jpeg" width="476" height="284.14285714285717" 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/__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F476e9f2d-2f8e-4f34-9551-83890bc6095e_784x468.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!dwVC!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F476e9f2d-2f8e-4f34-9551-83890bc6095e_784x468.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!dwVC!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F476e9f2d-2f8e-4f34-9551-83890bc6095e_784x468.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!dwVC!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F476e9f2d-2f8e-4f34-9551-83890bc6095e_784x468.jpeg 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption"><em>Left: Useful. Right: Not so much.</em></figcaption></figure></div><p>Another interesting mechanism, albeit not particularly relevant here, is &#8220;<a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC9748254/">frustrated phagocytosis</a>.&#8221; When the neutrophil extends its pseudopods to engulf and consume a target, generally, they will meet and encircle it; while that process is occurring, the production of the oxidative burst, via the NADPH pathway, is occurring in parallel. Think of it like saliva; you smell something tasty, you open your mouth, and independent of whatever your jaw is doing, your mouth is filling with saliva. If it <em>can&#8217;t</em> engulf its target, that process doesn&#8217;t stop - it just releases all that oxidative &#8220;saliva&#8221; externally instead. This tends to happen with flat bacterial biofilms, or larger organisms like fungi, that it simply can&#8217;t get its jaws around. Virions are tiny, so that doesn&#8217;t happen here, but &#8230; well, now you know. I love neutrophils. &#129392;</p><p>A high dose of ascorbic acid is rocket fuel to the neutrophil population. Even before the body has commenced their overproduction, there&#8217;s a good number of them around; they&#8217;re the ones we want to fuel up. With a sufficient threshold dose, chemotaxis and phagocytosis <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC5707683/">increase substantially</a>: they wake up and get to work, and each individual neutrophil <a href="https://www.mdpi.com/2072-6643/5/8/3131">lasts a lot longer</a> in doing so.</p><p>Within minutes, or sometimes seconds, with an appropriate dose - while 55mg/kg is a good baseline for your typical respiratory illnesses, some of the earliest scientific works in the 20th century had hypothesized different doses, some substantially higher, being needed for different pathogens of differing severities - viremia is completely and utterly obliterated, the inflammatory and oxidative immune response that generates most of the symptoms of illness is rapidly shut down, and very few free virions remain in the blood. The only source of them from that point forward is the already-infected cells that are producing them - this protocol <em>does not directly attack the infected cells</em> - it is, effectively, a hard reset of one&#8217;s viral load, and an inflammatory off-switch. Now you see them: now you don&#8217;t. It&#8217;s that fast.</p><p>It&#8217;s incredibly interesting how this protocol, or ones approximating it, seem to cyclically recur across history, from <a href="https://www.mv.helsinki.fi/home/hemila/CP/Klenner_1951_ch.pdf">Klenner</a>, <a href="https://lamclinic.com/blog/how-much-vitamin-c-should-i-take/">Pauling</a>, and others over time: while Klenner cited 65mg/kg, and Pauling different doses for different diseases, it would seem that this keeps being rediscovered independently over the years, and then buried, discovered again, buried again&#8230; and here we stand in 2025, having witnessed the latest efforts to bury it again first hand. Maybe we can end that cycle. Flu season simply does not need to be. Not even for a minute.</p><p></p><h4>Form</h4><p>Of course, to come back to where we started, these effects can only occur if the correct form of it was taken in the first place. If you&#8217;ve been following along, there are two properties we need for useful oral absorption: a very high dose, and in tiny, accessible particles. This is not, <em>at all</em>, an easy-to-come-by formulation; most preparations are either powdered and sugared to mix into a drink, and necessarily so, to defeat the incredibly bitter taste of it, or in compressed pill forms that greatly limit the speed of absorption.</p><p>No, we need something special: high-mesh, ideally 80+, pure, unsugared ascorbic acid powder. It can still be taken in a drink, although it&#8217;s going to taste extremely unpleasant; 000 gel or vegetable capsules are available, and they generally hold about a gram of powder each, give or take. There are also specialized devices available to fill a lot of them at once. If you can find pre-made capsules of plain powder, even better, although they&#8217;re probably going to be rabidly overpriced - but your kitchen will thank you.</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!glHy!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fbe7d8d17-2470-4bbb-a299-ea54f4897a89_784x550.jpeg" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!glHy!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fbe7d8d17-2470-4bbb-a299-ea54f4897a89_784x550.jpeg 424w, 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/__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fbe7d8d17-2470-4bbb-a299-ea54f4897a89_784x550.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!glHy!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fbe7d8d17-2470-4bbb-a299-ea54f4897a89_784x550.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!glHy!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fbe7d8d17-2470-4bbb-a299-ea54f4897a89_784x550.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!glHy!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fbe7d8d17-2470-4bbb-a299-ea54f4897a89_784x550.jpeg 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption"><em>Not what it looks like, officer!</em></figcaption></figure></div><p></p><h3>The Drawbacks</h3><p>Of course, nothing is ever quite that easy. However, the drawbacks are, depending on one&#8217;s health, relatively quite mild. Ivermectin has practically none: some have reported mild nausea, but on the whole, it has one of the best safety records of any drug in history - even the WHO <a href="https://x.com/verycosmic/status/1267261919762591744">wanted to hand it out to everyone</a>, at least until it <a href="https://www.who.int/news-room/feature-stories/detail/who-advises-that-ivermectin-only-be-used-to-treat-covid-19-within-clinical-trials">threatened</a> the Covid agenda. Ascorbic acid has a couple of main issues.</p><p>For starters, high oral doses of it, especially on an empty stomach, will typically cause some temporarily stomach upset. It is, after all, acid. There are basic forms of it available, such as sodium ascorbate; the drawback, of course, being that the body must first process them before being able to use them, thereby mitigating the mechanism by which we see that maximal benefit. That extends throughout the GI tract, and while every person is different, 55mg/kg is approximately at, or ever so slightly below, what is generally referred to as bowel tolerance; much above there, and the kidneys will rapidly expel it in the form of diarrhea, which can also be dehydrating. Fortunately, if it does happen, it&#8217;s a one-time event per dose. It is processed and expelled, whether immediately or in the ordinary slow course of metabolism, by the kidneys; it may be inappropriate for people with significant kidney dysfunction or disease, and it may exacerbate existing GI disease or injuries such as ulcers.</p><p>As with all of the protocols I&#8217;ve published, you should be aware that I am neither:</p><ul><li><p>A doctor;</p></li><li><p>Your doctor;</p></li><li><p>nor informed, at all, about the specifics of your body or medical condition;</p></li></ul><p>and, as such, I cannot provide you personalized medical advice, and this article should not be construed as such. You should <em>always</em> talk to your doctor before considering, starting or stopping any treatment. It&#8217;s not just a disclaimer; while your awareness of this is half the battle, the <em>other</em> half is <em>your doctor&#8217;s awareness.</em> We&#8217;ve seen the yawning gulf that can develop between the people and the medical profession; especially during Covid, as the medical field was saturated with propaganda and fraudulent studies; bringing this information to your doctor, such that they might read, learn, and apply this knowledge, maybe eventually publish some case studies, or maybe even start to speak up and inform others, is where we eventually start to cross the line from public awareness into institutional practice.</p><p></p><p>For the interested clinicians among you, I have several elucidating case studies attesting to the effect that I could share privately. Please reach out if you&#8217;d like to discuss it. I have also, many times, considered and been asked about offering consultations for particularly complex or difficult cases. While I have to draw a bright red line at offering personal medical advice, I have occasionally worked closely with practitioners to guide their understanding and implementations of my and others&#8217; protocols, and I could generally be available to take on particularly difficult scientific questions or projects, where others might not have the time, ability or inclination. If you think this is something that you or your patients might need, or benefit from, please feel free to reach out.</p><h3></h3><h3>The world turns&#8230;</h3><p>We&#8217;ve been around this rodeo twice now. Once, for ivermectin for Covid, and once for the fenbendazole-ivermectin+ protocol for cancer. We&#8217;ve seen the onslaught of <a href="https://www.cnn.com/videos/media/2021/08/24/coronavirus-ivermectin-false-claims-right-wing-media-foreman-ebof-pkg-vpx.cnn">propaganda</a>; the <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC8884777/">falsified studies</a>, the <a href="https://www.youtube.com/watch?v=7Hln4_iMp8E">propaganda</a>, the <a href="https://www.cnn.com/videos/health/2021/09/07/ivermectin-oklahoma-hospitals-dale-fact-check-newday-vpx.cnn">expert debunkings</a>, the <a href="https://www.youtube.com/watch?v=KmXbjnRcFpM">propaganda</a>, the <a href="https://www.npr.org/sections/coronavirus-live-updates/2021/09/04/1034217306/ivermectin-overdose-exposure-cases-poison-control-centers">false poison control reports</a>, <em>and <a href="https://bidenwhitehouse.archives.gov/briefing-room/press-briefings/2021/12/17/press-briefing-by-white-house-covid-19-response-team-and-public-health-officials-74/">did I mention the propaganda</a>?! -</em> that will be unleashed. We all saw that. What also happened, in equal force, albeit far more insidious, was the proliferation of controlled opposition and limited hangouts. The formula is, by now, pretty clean. Pick a designated hero: give that person the airtime, the controversy, the hearings, the swarms of trolls and sycophants both; make sure, that even as they suck all the oxygen out of the room from those who were otherwise getting it done, and as they play the hero of the people, that they utterly discredit and beclown themselves, and the work itself, professionally, to insulate the field at large from any thoughts of serious adoption; become the face of it, and once your hero is firmly settled into that role, set about actively, perhaps openly sabotaging and destroying the people that had necessitated such drastic measures in the first place.</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!pl80!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd37a94fb-5b14-4d01-818d-4f1ddfe84876_1170x686.jpeg" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!pl80!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd37a94fb-5b14-4d01-818d-4f1ddfe84876_1170x686.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!pl80!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd37a94fb-5b14-4d01-818d-4f1ddfe84876_1170x686.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!pl80!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd37a94fb-5b14-4d01-818d-4f1ddfe84876_1170x686.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!pl80!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd37a94fb-5b14-4d01-818d-4f1ddfe84876_1170x686.jpeg 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!pl80!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd37a94fb-5b14-4d01-818d-4f1ddfe84876_1170x686.jpeg" width="522" height="306.0615384615385" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/d37a94fb-5b14-4d01-818d-4f1ddfe84876_1170x686.jpeg&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:686,&quot;width&quot;:1170,&quot;resizeWidth&quot;:522,&quot;bytes&quot;:null,&quot;alt&quot;:&quot;We always give the public their heroes. We give the heroes to every  faction, and then people once they hear this person say all the right  things, we give releases to them&quot;,&quot;title&quot;:null,&quot;type&quot;:null,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:null,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="We always give the public their heroes. We give the heroes to every  faction, and then people once they hear this person say all the right  things, we give releases to them" title="We always give the public their heroes. We give the heroes to every  faction, and then people once they hear this person say all the right  things, we give releases to them" srcset="/__u/substackcdn.com/image/fetch/$s_!pl80!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd37a94fb-5b14-4d01-818d-4f1ddfe84876_1170x686.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!pl80!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd37a94fb-5b14-4d01-818d-4f1ddfe84876_1170x686.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!pl80!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd37a94fb-5b14-4d01-818d-4f1ddfe84876_1170x686.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!pl80!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd37a94fb-5b14-4d01-818d-4f1ddfe84876_1170x686.jpeg 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption"><em>SOP.</em></figcaption></figure></div><p>Can you believe that we&#8217;ve been doing this for <em>nearly</em> <em>six years</em>? The impacts of what we have done over time, on all these different fronts, one post, one call, one conversation at a time, are immense, as are the depths that have been plumbed in opposition. They&#8217;ve had a lot of time, a lot of years, a lot of experience and a lot of AI cycles to perfect the numerous strategies to limit these impacts. Ivermectin got through because we made it inevitable; that sabotage ensured that the other half of this protocol did not. Fenbendazole et al are getting through, because, you guessed it, we made it inevitable - <a href="https://x.com/veryvirology/status/1719909301677093030?s=20">educating 10,000 people a day</a>, with your testimonies and help, and alongside the years-long efforts of Dr. Makis and the thousands of lives that he has saved, it couldn&#8217;t have been any other way. Having started up with the very same tactics of co-option against that cancer protocol, this time they were headed off at the pass, and the response has been to utterly fragment, atomize and demoralize the entire medical freedom community, to completely lock down the discussion with censorship and suppression, newly supercharged for the modern era by the sheer competence of one Elon Musk, and steer the conversation around cancer treatment into billions more for mRNA research.</p><p>I don&#8217;t know exactly how we defeat that machine this time. I have some ideas, and in the face of what seems to be an pretty airtight regime of censorship now, I do know that we&#8217;re not going to do it alone. This protocol, notwithstanding the mild difficulty in obtaining and administering ascorbic acid in the proper form - for now, anyhow, because if history is any indication, then at least the Indian pharmas will probably pick it up pretty quickly, but it&#8217;s not going to be at your local drug store - works very, very quickly; whether you are a practitioner, seeing a new sick patient every day, or just a girl with a cold, it takes literally all of five minutes, or less, to see it work. You could, conceivably, keep some on hand, give it to a patient as they walk in with a cold, and by the time you&#8217;re done coding it, they&#8217;re bright as day and wondering how on Earth you did that! As they say - see something, say something. Speak up and tell a friend or two, share this article, share what you&#8217;ve learned with whomsoever might be inclined to listen, and maybe share it with a few that aren&#8217;t. A lot of needless misery will be stopped, lives will be saved, and all the right people will be hopping mad about it once we hit that critical mass again and the balance sheets start to suffer.</p><p></p><p>And while you are here, we still need your support. You may or may not have caught my last &#8220;<a href="/__u/veryvirology.substack.com/p/on-a-personal-note">article.</a>&#8221; For those of you who helped us through that, those of you who are still supporting us, and those that asked if we still need your help, you should know that thanks to you, we raised exactly what we needed - no more, no less - to survive what otherwise could well have been the end of us, there and then. We deeply appreciate that. It gets lonely out here sometimes, and we can&#8217;t even tell you what it meant that you were there for us. If it&#8217;s not one thing, it&#8217;s another, and we are far from our best while we struggle through one day to the next. Winter is coming - as of the last week, of fifteen degree nights and the first sprinklings of snow, and looking at 4-14 inches from today, it&#8217;s pretty much here - and we are not hardly ready for it. We made it through one catastrophe, but without the resources we need to truly prepare for the winter out here, much less the maintenance and rebuilding of the operational infrastructure that we should be doing besides, we&#8217;re still staring down the next. If you have the means, <a href="https://donate.stripe.com/3cs6qdbysat29LWdQT">we still very much need your support</a>.</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!tlrg!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fee8b0892-0e75-46d6-b93f-1640ec79e33b_2048x1536.png" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!tlrg!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fee8b0892-0e75-46d6-b93f-1640ec79e33b_2048x1536.png 424w, /__u/substackcdn.com/image/fetch/$s_!tlrg!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fee8b0892-0e75-46d6-b93f-1640ec79e33b_2048x1536.png 848w, /__u/substackcdn.com/image/fetch/$s_!tlrg!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fee8b0892-0e75-46d6-b93f-1640ec79e33b_2048x1536.png 1272w, /__u/substackcdn.com/image/fetch/$s_!tlrg!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fee8b0892-0e75-46d6-b93f-1640ec79e33b_2048x1536.png 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!tlrg!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fee8b0892-0e75-46d6-b93f-1640ec79e33b_2048x1536.png" width="530" height="397.5" 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/__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fee8b0892-0e75-46d6-b93f-1640ec79e33b_2048x1536.png 424w, /__u/substackcdn.com/image/fetch/$s_!tlrg!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fee8b0892-0e75-46d6-b93f-1640ec79e33b_2048x1536.png 848w, /__u/substackcdn.com/image/fetch/$s_!tlrg!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fee8b0892-0e75-46d6-b93f-1640ec79e33b_2048x1536.png 1272w, /__u/substackcdn.com/image/fetch/$s_!tlrg!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fee8b0892-0e75-46d6-b93f-1640ec79e33b_2048x1536.png 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption">It ain&#8217;t much, but it keeps us going. Our 2kw array, salvaged, bartered and running on our entirely hand-built system, giving us about 250w under this sky, which is just about exactly what we&#8217;re using. No grid power and no second chances out here.</figcaption></figure></div><p></p><p>Thank you for reading, thank you for standing by us, and if this protocol helps you, or somebody you know, please let us know!</p>]]></content:encoded></item><item><title><![CDATA[On a personal note...]]></title><description><![CDATA[The world keeps turning. Until it doesn't.]]></description><link>https://veryvirology.substack.com/p/on-a-personal-note</link><guid isPermaLink="false">https://veryvirology.substack.com/p/on-a-personal-note</guid><dc:creator><![CDATA[Adam Gaertner]]></dc:creator><pubDate>Thu, 06 Nov 2025 09:23:06 GMT</pubDate><enclosure url="https://substackcdn.com/image/fetch/$s_!AOOp!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F17727800-6b80-4730-a175-c2980ea74d2f_589x483.png" length="0" type="image/jpeg"/><content:encoded><![CDATA[<p>I miss the old Twitter. Censorious as they were, they were incredibly incompetent and ham-fisted about it. So long as you avoided using a few specific words they plugged in at any given time, the basic functions still worked: you followed people, people followed you, you could tweet to everyone and everyone would actually see it.</p><p>I remember, for a brief moment in &#8216;24, Musk&#8217;s algo completely broke for a few hours. I tweeted something, and it was read by about 30,000 people within about <em>five minutes.</em> Since then, they&#8217;ve had it pretty thoroughly locked down. I barely see anything from most of the people I follow, no matter which tab I use, and I&#8217;ll be lucky for any given post of my own to reach a thousand without DMing it to half the country.</p><p>The old management and coding team was, in all their DEI glory, deeply incompetent, and that allowed a measure of truly free speech to persist. Even with the FBI and the EU breathing down their necks to censor and manage the public discourse, they just didn&#8217;t have the intellectual faculties to do anything forum hosts weren&#8217;t doing in 1999.</p><p>Musk didn&#8217;t free the bird. He replaced obvious, ham-fisted, algorithmic banishments with the first truly modern, AI-powered censorship regime. &#8220;Freedom of speech, not freedom of reach&#8221; is a reasonable-sounding way to say, &#8220;we&#8217;ll decide who your friends are and what you&#8217;re all allowed to talk about.&#8221; I&#8217;ve lost contact with so many good friends because of Elon&#8217;s censorship regime. Fortunately, a lot of you subscribed here before it truly went downhill into complete unusability. In case you didn&#8217;t notice, they also recently took my blue check. That much further into the depths of the shadowban.</p><p>That loss, as I&#8217;m sure was their intent, also severely compromised my (and surely many others&#8217;) ability to do, and to live whilst doing, the kind of efforts to which we have dedicated the better part of the last six years of our lives. They turned X from a social network, one that was able to drive seismic changes in the world, into a glorified RSS news feed, that they control. That work was only possible because we were able to speak, organize, and be heard.</p><p>It was also nice, and necessary, to just be able to talk to people. Not everything had to be a big news announcement to potentially be seen. When you had questions, you could just come ask. Random conversations about nothing in particular ended up leading to some of the most substantial developments and connections that we made over these last few years. It&#8217;s barely worth trying to post anything but big breaking news these days. I&#8217;ll probably cross-post this, too, for the handful that might be allowed to lay eyes on it, for whatsoever that might be worth.</p><p></p><h4>I bring this up now&#8230;</h4><p>&#8230; because, frankly, we&#8217;re in trouble.</p><p>Not &#8216;we&#8217;, in the grand, we-the-people sense (although, that too.) My family and I are in trouble, and we could use some help right now.</p><p>We&#8217;ve been completely off-grid, 30 miles from the middle of nowhere, for the better part of this year. No road, no utilities, pretty much nothing at all but for sun, land and wind, wild horses, time, and a Starlink that has enabled us to carry on our work. If we&#8217;ve managed to stay in touch, we&#8217;ve probably talked about it, and if not - well - now you know, and we probably miss you, so come say hi. The comments are open below. Maybe Substack could become what Twitter used to be.</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!AOOp!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F17727800-6b80-4730-a175-c2980ea74d2f_589x483.png" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!AOOp!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F17727800-6b80-4730-a175-c2980ea74d2f_589x483.png 424w, /__u/substackcdn.com/image/fetch/$s_!AOOp!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F17727800-6b80-4730-a175-c2980ea74d2f_589x483.png 848w, /__u/substackcdn.com/image/fetch/$s_!AOOp!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F17727800-6b80-4730-a175-c2980ea74d2f_589x483.png 1272w, /__u/substackcdn.com/image/fetch/$s_!AOOp!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F17727800-6b80-4730-a175-c2980ea74d2f_589x483.png 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!AOOp!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F17727800-6b80-4730-a175-c2980ea74d2f_589x483.png" width="589" height="483" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/17727800-6b80-4730-a175-c2980ea74d2f_589x483.png&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:483,&quot;width&quot;:589,&quot;resizeWidth&quot;:null,&quot;bytes&quot;:315832,&quot;alt&quot;:null,&quot;title&quot;:null,&quot;type&quot;:&quot;image/png&quot;,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:&quot;https://veryvirology.substack.com/i/178153302?img=https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F17727800-6b80-4730-a175-c2980ea74d2f_589x483.png&quot;,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="" srcset="/__u/substackcdn.com/image/fetch/$s_!AOOp!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F17727800-6b80-4730-a175-c2980ea74d2f_589x483.png 424w, /__u/substackcdn.com/image/fetch/$s_!AOOp!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F17727800-6b80-4730-a175-c2980ea74d2f_589x483.png 848w, /__u/substackcdn.com/image/fetch/$s_!AOOp!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F17727800-6b80-4730-a175-c2980ea74d2f_589x483.png 1272w, /__u/substackcdn.com/image/fetch/$s_!AOOp!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F17727800-6b80-4730-a175-c2980ea74d2f_589x483.png 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption"><em>In case you thought &#8220;middle of nowhere&#8221; was an overstatement.</em></figcaption></figure></div><p>Since the events of late &#8216;23, in part as evolved from our visit to Mar-a-Lago, and the two years of ceaseless assault on our family and our work from every conceivable angle that ensued, this seemed like the wiser place to be. Given that the vast majority of our work is research, development, organizing, and making the news now and then, it&#8217;s been perfectly feasible, and generally a lot safer, to carry out that work from our little slice of the middle of nowhere out here.</p><p>Well - that changed last night. As of right now, due to the rather foreseeable consequences of a lot of long-deferred maintenance, our last vehicle - out of the two that we brought - broke down, and we are all but stranded out here, with a few more days of food and water, and about $50 to our name. And $50 ain&#8217;t enough for a tow. Much less the long-overdue repair that it needs.</p><p>X&#8217;s censorship isn&#8217;t the only reason I&#8217;ve been quieter lately. After spending the last five years doing what we&#8217;ve been doing, and doing it very publicly, I made a judgment call after the election: we won, so now it&#8217;s time to set these various things right through official, private channels, right? The time for rallying the world, bringing people together to demand what was right, and saving lives from the merciless regime propaganda was all but over, for everyone but those who just love the attention so much they couldn&#8217;t bear to step out of the limelight, and it was time to get to work on bringing this war to a close, seeing justice done, and setting things right.</p><p>Well, a year later, I can confidently say that that was emphatically the wrong call. &#8220;We&#8221; did not win, the people that should have been given offices were not, and our newly elected leadership appears to have little to no intention of ever setting any of this right, from the top on down. I&#8217;m in the middle of another article about why I decided against taking a role in the admin, which should be quite elucidating as to what I&#8217;ve learned over the last year, but suffice to say, at least in terms of continuing this work, that was decidedly the right call. In terms of survival, though?&#8230; maybe it would have been wise. It sure would have made life a whole lot easier than it&#8217;s been.</p><p>It&#8217;s been a long, long time since we have asked for your support. Even as we are deeply grateful for your continued support here, we&#8217;ve learned the hard way that releasing cures <a href="https://www.cnbc.com/2018/04/11/goldman-asks-is-curing-patients-a-sustainable-business-model.html">just isn&#8217;t a sustainable business model</a>. We never considered it business; we do the work that we do for the betterment of humanity, in any capacity we find ourselves able; but after a year spent making the world aware of IVM and FBZ&#8217; extraordinary utility for cancer treatment, our standard of living has been ever so gradually declining. I never was much for the clickbait, high-frequency news publishing; once I publish a cure, it&#8217;s out, and that seems to be about all there is to it as others eventually pick it up and run with it. Nevertheless, I&#8217;ve been working, for quite a while and as time and wherewithal has permitted, on a cure protocol for vaccine-induced autoimmune disorders at large, and I think I am relatively close to having it fleshed out and nailed down now, albeit with a lot of work yet to be done. Thanks to your continued support, we have been able to maintain a pretty minimal subsistence, which is all we ever wanted to still be able to carry on this work, but the sacrifices we&#8217;ve had to make are starting to add up. Vehicle maintenance among them. &#129301;</p><p>There is a deep rot in this admin that is going to necessitate a very different approach if we ever want to see justice done; for the victims, for the criminals who committed this genocide, and for the people still being harmed and lied to to this day; my research efforts are still ongoing; and if and when we can get through this very unpleasant period, I think that we are otherwise very well positioned to carry on this fight, turn it around, and begin meaningfully organizing again in light of what we now know.</p><p>We&#8217;ve been living on very little for a very long time, reluctant to ask for any support beyond what so many of you have already been regularly providing us here, and it just makes everything so much harder than it needs to be. We&#8217;ve sacrificed so much to come this far, and I do not think that we are done - but that truly appears to be out of our hands right now.</p><p>If our work over these last six years has been of any value to you, or your friends and loved ones, and if you have the means, we need your support right now. We can&#8217;t do it alone.</p><div class="native-video-embed" data-component-name="VideoPlaceholder" data-attrs="{&quot;mediaUploadId&quot;:&quot;9d6a0a16-ec74-4b31-a187-15995b36bc40&quot;,&quot;duration&quot;:null}"></div><p><em>The sound of the last two wheel studs holding on for dear life. At least we made it most of the way...</em></p><p></p><p>My Stripe direct link: [removed]</p><p></p><p>Cash App: $AdamGaertner</p><p></p><p>Things that would greatly improve our lives out here: <a href="https://www.amazon.com/hz/wishlist/ls/3PJ16D8Y2OH6X/ref=nav_wishlist_lists_2">Amazon</a></p><p></p><p>Hope to hear from you in the comments.</p>]]></content:encoded></item><item><title><![CDATA[New Study Confirms IgG4 Class Switch]]></title><description><![CDATA[mRNA vaccines increase susceptibility to severe disease.]]></description><link>https://veryvirology.substack.com/p/new-study-confirms-igg4-class-switch</link><guid isPermaLink="false">https://veryvirology.substack.com/p/new-study-confirms-igg4-class-switch</guid><dc:creator><![CDATA[Adam Gaertner]]></dc:creator><pubDate>Sat, 01 Nov 2025 23:00:42 GMT</pubDate><enclosure url="https://substackcdn.com/image/fetch/$s_!x0CM!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F07ac16e4-dacd-4569-864b-17614fa87fd4_1080x596.jpeg" length="0" type="image/jpeg"/><content:encoded><![CDATA[<p>The bad news just keeps coming for the mRNA guinea pigs.</p><p>I wrote, <a href="/__u/veryvirology.substack.com/p/igg4-antibody-class-switch-end-of">a couple of years ago</a>, about the likelihood of mRNA vaccines inducing an IgG4 class switch, and the consequences that would have for those who took those shots. In short, because of the long-term persistence of the spike protein, instead of staying in the arm and being gone in a couple of days as was promised, that persistent exposure, lasting months, years or potentially indefinitely, instead trains the immune system to ignore and disregard a viral infection. Similarly to the archetypal case of pollens, when an otherwise healthy immune system encounters a foreign body, and it persists for long enough, the body undergoes a <a href="https://onlinelibrary.wiley.com/doi/full/10.1038%2Ficb.2014.48#:~:text=Figure%201,a%20more%20downstream%20IgG%20subclass.">cascading response</a>, switching between IgG subclasses from one, to two, to three, and eventually arriving at IgG4.</p><p>IgG4 is called the <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC12071442/">anti-antibody.</a> Every antibody subclass serves as a flag for the immune system. With classes one through three, and from the broader IgM/IgA types that will <a href="https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2020.01943/full">bind to nearly anything</a>, versus the custom-made IgG type that is produced to bind to one specific antigen, one recognizable part of some foreign body, the antibody activates the rest of the immune response; the complement cascade begins, various immune cells release signaling chemokines and cytokines to recruit immune cells to the site of the infection, and the immune response begins in earnest. In contrast, IgG4 serves the opposite purpose; the immune cells that meet it will be disabled, the local complement cascade will be interrupted and pacified, and the immune system is told, &#8220;Don&#8217;t worry about this one. He&#8217;s harmless.&#8221;</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!TAVU!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F73c617f9-3be1-4aff-b2ce-281cc344660f_1536x1024.png" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!TAVU!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F73c617f9-3be1-4aff-b2ce-281cc344660f_1536x1024.png 424w, /__u/substackcdn.com/image/fetch/$s_!TAVU!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F73c617f9-3be1-4aff-b2ce-281cc344660f_1536x1024.png 848w, /__u/substackcdn.com/image/fetch/$s_!TAVU!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F73c617f9-3be1-4aff-b2ce-281cc344660f_1536x1024.png 1272w, /__u/substackcdn.com/image/fetch/$s_!TAVU!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F73c617f9-3be1-4aff-b2ce-281cc344660f_1536x1024.png 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!TAVU!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F73c617f9-3be1-4aff-b2ce-281cc344660f_1536x1024.png" width="532" height="354.78846153846155" 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/__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F73c617f9-3be1-4aff-b2ce-281cc344660f_1536x1024.png 424w, /__u/substackcdn.com/image/fetch/$s_!TAVU!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F73c617f9-3be1-4aff-b2ce-281cc344660f_1536x1024.png 848w, /__u/substackcdn.com/image/fetch/$s_!TAVU!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F73c617f9-3be1-4aff-b2ce-281cc344660f_1536x1024.png 1272w, /__u/substackcdn.com/image/fetch/$s_!TAVU!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F73c617f9-3be1-4aff-b2ce-281cc344660f_1536x1024.png 1456w" sizes="100vw" fetchpriority="high"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption">About the sum of it.</figcaption></figure></div><p>This is a necessary adaptation to prevent an otherwise damaging inflammatory response to ever-present foreign bodies such as pervasive pollen in the spring. The <a href="https://aacijournal.biomedcentral.com/articles/10.1186/s13223-020-00427-z">failure</a> of this mechanism, among others, manifests as hayfever; a completely pointless, damaging inflammatory response is induced, where none is necessary. A few molecules of pollen (generally) aren&#8217;t actually going to hurt you; IgG4 is among the body&#8217;s mechanisms to recognize that, and call off the cavalry.</p><p>What you don&#8217;t want is an IgG4 response to a replicating pathogen that is going to harm you - and that&#8217;s exactly what the mRNA shots are, <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC10222767/">quite foreseeably</a>, causing.</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!O3-z!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F2e6b08ab-924c-492b-a78b-8210fde52446_1024x1024.png" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!O3-z!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F2e6b08ab-924c-492b-a78b-8210fde52446_1024x1024.png 424w, /__u/substackcdn.com/image/fetch/$s_!O3-z!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F2e6b08ab-924c-492b-a78b-8210fde52446_1024x1024.png 848w, /__u/substackcdn.com/image/fetch/$s_!O3-z!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F2e6b08ab-924c-492b-a78b-8210fde52446_1024x1024.png 1272w, /__u/substackcdn.com/image/fetch/$s_!O3-z!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F2e6b08ab-924c-492b-a78b-8210fde52446_1024x1024.png 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!O3-z!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F2e6b08ab-924c-492b-a78b-8210fde52446_1024x1024.png" width="338" height="338" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/2e6b08ab-924c-492b-a78b-8210fde52446_1024x1024.png&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:1024,&quot;width&quot;:1024,&quot;resizeWidth&quot;:338,&quot;bytes&quot;:2240226,&quot;alt&quot;:null,&quot;title&quot;:null,&quot;type&quot;:&quot;image/png&quot;,&quot;href&quot;:null,&quot;belowTheFold&quot;:false,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:&quot;https://veryvirology.substack.com/i/177749626?img=https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F2e6b08ab-924c-492b-a78b-8210fde52446_1024x1024.png&quot;,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="" srcset="/__u/substackcdn.com/image/fetch/$s_!O3-z!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F2e6b08ab-924c-492b-a78b-8210fde52446_1024x1024.png 424w, /__u/substackcdn.com/image/fetch/$s_!O3-z!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F2e6b08ab-924c-492b-a78b-8210fde52446_1024x1024.png 848w, /__u/substackcdn.com/image/fetch/$s_!O3-z!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F2e6b08ab-924c-492b-a78b-8210fde52446_1024x1024.png 1272w, /__u/substackcdn.com/image/fetch/$s_!O3-z!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F2e6b08ab-924c-492b-a78b-8210fde52446_1024x1024.png 1456w" sizes="100vw"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption">Guys?&#8230;</figcaption></figure></div><p>A <a href="https://www.medrxiv.org/content/10.1101/2025.10.26.25338845v1.full">new, preprint study</a>, just published from the University of Amsterdam, has confirmed exactly what we said was going to happen: after a long delay, up to six months or more after taking at least two shots, the immune response in mRNA vaccinees eventually switches to the non-inflammatory IgG4 subclass.</p><p>This is bad news bears for, it appears, anybody that took those shots.</p><p></p><h3>The Study</h3><p>The researchers followed four cohorts of patients undergoing treatment for kidney disease. The study included only those who had taken at least two COVID-19 mRNA &#8220;vaccines,&#8221; and studied the patients&#8217; immunologically healthy, unvaccinated family members or close associates for their control groups. Baseline levels were measured 28 days after vaccination, with IgG4 consisting of 3-5%, versus IgG1 at 55-65%; later, between two and six months after their second dose, almost all of the studied patients had substantially elevated anti-Spike IgG4 levels, up to five times their starting prevalence at 10-15%, with subtypes two and three having all but vanished, and IgG1 levels remaining stable.</p><p>This is an interesting development. In a full class switch, IgG1 tends to vanish almost completely, to be replaced with IgG4 almost exclusively. Here, only IgG2 and IgG3 vanished, and IgG4, rather than completely taking over, was only elevated in the response, with IgG1 proportions remaining stable.</p><p>The effect documented in this particular study is in fact <em>substantially milder</em> than some previous studies. A favored strategy for bad science is to publish the data, and then to <a href="https://x.com/veryvirology/status/1613727157863469057">mess with the abstract and conclusions</a> - for a generation of practitioners who slept through school, unable or unwilling to actually read beyond the headlines, it&#8217;s a very simple matter for one&#8217;s conclusions to bear absolutely no resemblance to the data they&#8217;re drawn from. An <a href="https://www.science.org/doi/10.1126/sciimmunol.adg7015">earlier study</a>, this one in 2023 (<em>h/t Dr. Lynn Fynn for bringing it up, thank you!)</em>, showed a post-vaccine IgG4 dominance up to <strong>80%</strong> in animal studies - and still managed to endorse them in the abstract. That alone should have been enough to hit pause on this. Thank God that our immune systems are a little more resilient than those of our primate cousins.</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!x0CM!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F07ac16e4-dacd-4569-864b-17614fa87fd4_1080x596.jpeg" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!x0CM!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F07ac16e4-dacd-4569-864b-17614fa87fd4_1080x596.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!x0CM!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F07ac16e4-dacd-4569-864b-17614fa87fd4_1080x596.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!x0CM!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F07ac16e4-dacd-4569-864b-17614fa87fd4_1080x596.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!x0CM!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F07ac16e4-dacd-4569-864b-17614fa87fd4_1080x596.jpeg 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!x0CM!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F07ac16e4-dacd-4569-864b-17614fa87fd4_1080x596.jpeg" width="482" height="265.9925925925926" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/07ac16e4-dacd-4569-864b-17614fa87fd4_1080x596.jpeg&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:596,&quot;width&quot;:1080,&quot;resizeWidth&quot;:482,&quot;bytes&quot;:72837,&quot;alt&quot;:null,&quot;title&quot;:null,&quot;type&quot;:&quot;image/jpeg&quot;,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:&quot;https://veryvirology.substack.com/i/177749626?img=https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F07ac16e4-dacd-4569-864b-17614fa87fd4_1080x596.jpeg&quot;,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="" srcset="/__u/substackcdn.com/image/fetch/$s_!x0CM!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F07ac16e4-dacd-4569-864b-17614fa87fd4_1080x596.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!x0CM!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F07ac16e4-dacd-4569-864b-17614fa87fd4_1080x596.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!x0CM!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F07ac16e4-dacd-4569-864b-17614fa87fd4_1080x596.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!x0CM!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F07ac16e4-dacd-4569-864b-17614fa87fd4_1080x596.jpeg 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption">They&#8217;re the ones that survived. <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC7483033/">They weren&#8217;t all quite so lucky</a>. <em>Routhu, N. K., Stampfer, S. D., et al. (2023). Efficacy of mRNA-1273 and Novavax ancestral or BA.1 spike booster vaccines against SARS-CoV-2 BA.5 infection in nonhuman primates. Science Immunology, 8(88), adg7015. https://doi.org/10.1126/sciimmunol.adg7015</em></figcaption></figure></div><p></p><h3>Complete vs Partial Class Switch</h3><p>The subtlety of the switch belies its effect. IgG4 is a potent immunosuppressant; it does not need to completely take over to exert an outsized effect. Most of the body&#8217;s systems rely on homeostasis, and various levels of signal and countersignal, as I&#8217;ve covered in previous articles; a given pathway will be affected by both agonists and antagonists, with competing levels of &#8220;peace&#8221; versus &#8220;war&#8221; signals, and the eventual response will be determined by which is stronger at any given time.</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!Q6MB!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F7d2f700e-6a40-4207-b803-6767a088556e_1024x1024.png" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!Q6MB!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F7d2f700e-6a40-4207-b803-6767a088556e_1024x1024.png 424w, /__u/substackcdn.com/image/fetch/$s_!Q6MB!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F7d2f700e-6a40-4207-b803-6767a088556e_1024x1024.png 848w, /__u/substackcdn.com/image/fetch/$s_!Q6MB!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F7d2f700e-6a40-4207-b803-6767a088556e_1024x1024.png 1272w, /__u/substackcdn.com/image/fetch/$s_!Q6MB!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F7d2f700e-6a40-4207-b803-6767a088556e_1024x1024.png 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!Q6MB!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F7d2f700e-6a40-4207-b803-6767a088556e_1024x1024.png" width="310" height="310" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/7d2f700e-6a40-4207-b803-6767a088556e_1024x1024.png&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:1024,&quot;width&quot;:1024,&quot;resizeWidth&quot;:310,&quot;bytes&quot;:2263565,&quot;alt&quot;:null,&quot;title&quot;:null,&quot;type&quot;:&quot;image/png&quot;,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:&quot;https://veryvirology.substack.com/i/177749626?img=https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F7d2f700e-6a40-4207-b803-6767a088556e_1024x1024.png&quot;,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="" srcset="/__u/substackcdn.com/image/fetch/$s_!Q6MB!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F7d2f700e-6a40-4207-b803-6767a088556e_1024x1024.png 424w, /__u/substackcdn.com/image/fetch/$s_!Q6MB!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F7d2f700e-6a40-4207-b803-6767a088556e_1024x1024.png 848w, /__u/substackcdn.com/image/fetch/$s_!Q6MB!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F7d2f700e-6a40-4207-b803-6767a088556e_1024x1024.png 1272w, /__u/substackcdn.com/image/fetch/$s_!Q6MB!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F7d2f700e-6a40-4207-b803-6767a088556e_1024x1024.png 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption">Which way, western cell?</figcaption></figure></div><p>IgG4 works a little differently. When an immune cell responds to an IgG1 antibody, it&#8217;s likely only there because it&#8217;s already been summoned to the site of infection; some cells will continue to amplify the signal, while most will just get to work attacking the foreign body. An IgG4 response, on the other hand, takes priority. The antibody manually interrupts the complement cascade, binding to C3a, preventing C3b deposition; immune cells that are told to stand down will reliably repeat and amplify those orders. One IgG4 calling for peace will be heard and amplified more loudly than ten IgG 1-3 encounters.</p><p>Of course, there is a silver lining. The fact that IgG1 remains dominant means that, at any given site of infection, there&#8217;s a reasonable chance that there won&#8217;t be any IgG4 present for at least a while, and the immune system will still be able to do most of its work. If IgG4 were dominant, the effect would be comparable to AIDS; even with an otherwise healthy immune system, even boosted in its power by the common C and D vitamins, the response would be completely shut off, and the viral infection would be free to run rampant, causing extensive tissue destruction, blood clotting, releases of stressor chemokines, and the various other unavoidable signals induced by cell death, until it ends up overwhelmed by that pervasive counter-signal; at that point, very late in the course of an infection run rampant, a cytokine storm would commence, with the body realizing it has some catching up to do against that infection; inflammatory artillery starts firing everywhere, all at once, and massive tissue destruction and death follows in relatively short order without intensive medical care, and even then it&#8217;s a crapshoot. Cytokine storms were, for a time, the leading, direct end-stage cause of death for those in hospital with severe COVID-19, frequently following bacterial infection from incompetently executed intubations causing mechanical injury to throat or lung tissue.</p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://veryvirology.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">To receive new articles and support this work, please consider becoming a free or paid subscriber. It makes a difference!</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div><p></p><h3>The Immune Microenvironment</h3><p>An immune response is, generally - except in cases of cytokine storm - hyper-localized to the site of infection. Consider that everything that constitutes the immune system is carried in and by the blood, which is constantly rushing by, never static. Immune cells that were, five seconds ago, moving through your heart, calmed and idled by the absence of any antibody or chemokine signal, only momentarily find themselves, by pure chance, rushing by the site of an infection and suddenly in receipt of that alarm.</p><p>The alarm, too, travels through the blood. A cell that releases an alarm, in the form of various molecular chemokines or cytokines, will see those molecules rushed away in the bloodstream. Immune cell motility - their ability to choose a direction in which to move, to follow an alarm to its source - is based upon these cytokines. A CD8 cell in your leg, where nothing in particular is going on, will be in an environment that is saturating it with &#8216;peace&#8217; signals; when it smells an alarm, it will physically move in the direction of that alarm, trying to get closer to the site of infection.</p><p>As it moves closer to the site of infection, that signal gradient will gradually shift away from the bias toward peace, and the volume of that alarm will steadily increase; closer to the infection, there are more cells releasing those alarms, and increasingly fewer &#8216;peace&#8217; signals. This balance is instructive to the cell as to whether it needs to be in attack mode yet.</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!VMow!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fcdbe8401-0708-46bb-b689-5644f581d2d9_1024x1024.png" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!VMow!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fcdbe8401-0708-46bb-b689-5644f581d2d9_1024x1024.png 424w, /__u/substackcdn.com/image/fetch/$s_!VMow!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fcdbe8401-0708-46bb-b689-5644f581d2d9_1024x1024.png 848w, /__u/substackcdn.com/image/fetch/$s_!VMow!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fcdbe8401-0708-46bb-b689-5644f581d2d9_1024x1024.png 1272w, /__u/substackcdn.com/image/fetch/$s_!VMow!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fcdbe8401-0708-46bb-b689-5644f581d2d9_1024x1024.png 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!VMow!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fcdbe8401-0708-46bb-b689-5644f581d2d9_1024x1024.png" width="290" height="290" 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/__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fcdbe8401-0708-46bb-b689-5644f581d2d9_1024x1024.png 424w, /__u/substackcdn.com/image/fetch/$s_!VMow!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fcdbe8401-0708-46bb-b689-5644f581d2d9_1024x1024.png 848w, /__u/substackcdn.com/image/fetch/$s_!VMow!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fcdbe8401-0708-46bb-b689-5644f581d2d9_1024x1024.png 1272w, /__u/substackcdn.com/image/fetch/$s_!VMow!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fcdbe8401-0708-46bb-b689-5644f581d2d9_1024x1024.png 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption">Hi ho, hi ho, it&#8217;s off to war we go...</figcaption></figure></div><p><a href="https://www.cell.com/cell-reports/fulltext/S2211-1247(25)00771-5">IgG4 is among the strongest &#8216;peace&#8217; signals</a>. As it processes the increasingly pervasive gradient of alarm signals, and draws closer to the site of infection, it&#8217;s still being saturated with both types of general signals; if it started in the leg, and an infection is in, say, the groin, the cells in the knee are still saying everything&#8217;s fine, but that smell of danger is getting stronger. The most effective cells aren&#8217;t generalists; CD8, the heavy artillery, are largely produced specifically to respond to one epitope of one hostile foreign body. While the immune system is ever present, we don&#8217;t walk around with an army of cells ready to attack some specific pathogen or another. There&#8217;s billions of potential pathogens, with billions of potential protein conformations that could be recognized by any one cell; we can&#8217;t keep them all, in quantity, all the time. While there&#8217;s generally <em>some </em>present, for most types of potential infection, their quantity is minimal and residual from the last time that pathogen was seen in the body.</p><p>That is also, coincidentally, the reason why the practice of measuring actively circulating antibody levels against SARS-CoV-2, as a proxy for whether one is protected, or in need of another booster, is quite insane. That faulty approach was used to justify instructing people to get one booster after another: just one more of the genocidal frauds perpetrated on the world by Dr. Fauci.</p><p>A properly established immune response will create memory B-cells, which then sit idle until their pathogen is encountered, and <em>only then</em> will they flood the body with antibodies and immune cells tailored to that pathogen; it is not natural to walk around with persistently high levels of antibodies for a pathogen you have not recently encountered. That is the primary reason this class shift has occurred - that unnatural, ever-present exposure is what drives the class switch. The logic that evolved here is, effectively, that if we&#8217;ve been on consistent high alert against a foreign body, that has been continually present for six months now, and you&#8217;re still here to tell the tale, then it&#8217;s probably harmless, and your immune system should stop overreacting.</p><p>This is also a major method by which immunological cancer therapies will eventually, if not rapidly effecting a complete or near-complete clearance, <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC7443307/">induce tolerance</a> toward tumors and cancers. It&#8217;s exactly the same process, and irreversible; as cancers tend to evolve, under extreme pressure, numerous immune evasive features that prevent any recognition of some cells, that timer does not actually begin until the pharmaceutical immune interventions that unmask them are commenced. From the moment those tumors are made visible for an immune response, where they were previously invisible, the clock is ticking toward an IgG4 class switch and a substantial shutdown of the immune response.</p>
      <p>
          <a href="/__u/veryvirology.substack.com/p/new-study-confirms-igg4-class-switch">
              Read more
          </a>
      </p>
   ]]></content:encoded></item><item><title><![CDATA[Lost Knowledge: Obesity]]></title><description><![CDATA[Without the will, there's still a way.]]></description><link>https://veryvirology.substack.com/p/lost-knowledge-obesity</link><guid isPermaLink="false">https://veryvirology.substack.com/p/lost-knowledge-obesity</guid><dc:creator><![CDATA[Adam Gaertner]]></dc:creator><pubDate>Sat, 11 Oct 2025 22:57:54 GMT</pubDate><enclosure url="https://substackcdn.com/image/fetch/$s_!40hb!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F2fd6e6ed-9793-48b8-bd3f-759704d90ec5_1536x716.png" length="0" type="image/jpeg"/><content:encoded><![CDATA[<p><em>Author&#8217;s note: A lot of difficult debate and review went into the decision to publish this article. By popular demand, with over 90% of respondents voting for publication, here it is. This is a rare kind of dangerous information; while everything here is, more or less, available elsewhere, piecemeal, and spread over dozens of sources of variable veracity, few so comprehensively cover both the risks and mitigations to be had, alongside these extraordinary actions. I hope that the compilation of this knowledge here will outweigh the risk of misuse. Please learn wisely, talk to your doctor, share as may be needed, and above all, be safe.</em></p><p><em>With great power comes great responsibility.</em></p><div class="captioned-image-container"><figure><a class="image-link image2" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!40hb!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F2fd6e6ed-9793-48b8-bd3f-759704d90ec5_1536x716.png" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!40hb!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F2fd6e6ed-9793-48b8-bd3f-759704d90ec5_1536x716.png 424w, /__u/substackcdn.com/image/fetch/$s_!40hb!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F2fd6e6ed-9793-48b8-bd3f-759704d90ec5_1536x716.png 848w, /__u/substackcdn.com/image/fetch/$s_!40hb!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F2fd6e6ed-9793-48b8-bd3f-759704d90ec5_1536x716.png 1272w, /__u/substackcdn.com/image/fetch/$s_!40hb!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F2fd6e6ed-9793-48b8-bd3f-759704d90ec5_1536x716.png 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!40hb!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F2fd6e6ed-9793-48b8-bd3f-759704d90ec5_1536x716.png" width="506" height="235.97115384615384" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/2fd6e6ed-9793-48b8-bd3f-759704d90ec5_1536x716.png&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:679,&quot;width&quot;:1456,&quot;resizeWidth&quot;:506,&quot;bytes&quot;:2624559,&quot;alt&quot;:null,&quot;title&quot;:null,&quot;type&quot;:&quot;image/png&quot;,&quot;href&quot;:null,&quot;belowTheFold&quot;:false,&quot;topImage&quot;:true,&quot;internalRedirect&quot;:&quot;https://veryvirology.substack.com/i/175750836?img=https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F2fd6e6ed-9793-48b8-bd3f-759704d90ec5_1536x716.png&quot;,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="" srcset="/__u/substackcdn.com/image/fetch/$s_!40hb!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F2fd6e6ed-9793-48b8-bd3f-759704d90ec5_1536x716.png 424w, /__u/substackcdn.com/image/fetch/$s_!40hb!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F2fd6e6ed-9793-48b8-bd3f-759704d90ec5_1536x716.png 848w, /__u/substackcdn.com/image/fetch/$s_!40hb!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F2fd6e6ed-9793-48b8-bd3f-759704d90ec5_1536x716.png 1272w, /__u/substackcdn.com/image/fetch/$s_!40hb!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F2fd6e6ed-9793-48b8-bd3f-759704d90ec5_1536x716.png 1456w" sizes="100vw" fetchpriority="high"></picture><div></div></div></a><figcaption class="image-caption"><em>Days gone by.</em></figcaption></figure></div><p>In every category that exists, everything from metallurgy, to education, to therapeutics, there&#8217;s a best-in-class; a gold standard, that one single approach that stands indisputably head-and-shoulders over the rest of the heap. When it comes to fighting ssRNA viral infections, at all phases of disease, ivermectin shines; for fly-with-a-bazooka immune suppression, it&#8217;s tacrolimus; for tensile strength at high temperature, it&#8217;s tungsten; once upon a time, before they were infected by communism, Harvard would have been best-in-class for education. I try to confine my work and my writings, on whichever subject they may be, to only the stand-out bests, and when it comes to weight loss, there&#8217;s two of them, depending on how you&#8217;re coming at it. The first, of course, is diet and exercise; no big secret there. If one expends more energy than they consume, and manages to keep their body out of starvation mode and actually burning those calories, those pounds of fat will melt off pretty quickly. Modern foods tend to pack enormous amounts of calories into relatively small portions; there&#8217;s <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC11843978/">a very good reason</a> that the poorest among us also tend to be the heaviest. While RFK&#8217;s soda ban for food stamp recipients is a good starting point, when calorie-dense, processed junk food ends up <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC10200457/">cheaper</a> than home-cooked, healthy meals, the problem runs a lot deeper than just soda.</p><p>However, there is a second route (and no, it&#8217;s not Ozempic.) The <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC9071483/">baseline principle</a> is the same; with more energy out than in, fat gets burned. However, that common-sense approach has its limits. Obesity often comes with its own, self-reinforcing set of challenges. Even when the morbidly obese - among which we now count fully ten percent of Americans, with <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC3527647/">forty percent merely obese</a> - finally do decide to take real steps toward fixing their health, they frequently find they are <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC10729542/">no longer able to do so</a>, or only minimally so. Carrying all that weight around causes injuries, in and of itself; from back problems, to respiratory distress, or overloaded hips and joints creaking and cracking, the morbidly obese often find themselves in a catch-22, trapped in a prison of their own consumption, unable to do the right thing. Younger people are, of course, less likely to find themselves there, and generally, with the willpower to push through, can fight their way through it; but especially as aging takes its toll, that can cease to be the case.</p><p>A lot of knowledge was lost in the early 20th century. As the <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC3543812/">Rockefellers</a> promulgated and cemented their profit-driven vision of medicine throughout the 1910s, 20s and 30s, establishing the labyrinthine system of medicine and the multi-trillion dollar sick-care industry that blights us today, new problems had to be created, and old ones brought back, to be facetiously &#8220;solved&#8221; again through the regulatory and educational morass that Dr. Fauci played like a fiddle to exact his genocide against the world, and the US particularly, throughout the pandemic. Among those pieces of knowledge, banned in the late 1930s, due to the (very real) risks of overdose - as exist for any drug, most notably and recently Tylenol - was the extraordinary, gold-standard weight loss effects of <strong><a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC3550200/">2,4-Dinitrophenol</a></strong>.</p><p>With <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC9272494/">Ozempic</a>, generally held by the world as the current gold standard, four pounds of weight loss, per month, is hailed as a miracle. While in context of what one would expect from good old diet and exercise, it&#8217;s nothing to sneeze at - presuming you don&#8217;t mind the &#8220;safe and effective&#8221; side effects - it&#8217;s the kiddie pool compared to what&#8217;s possible. Four pounds, depending on one&#8217;s starting point, might be roughly what you&#8217;d expect to see in <em>one</em> <em>single day</em> of treatment with 2,4-DNP. The drug stands alone in a category all its own when it comes to burning fat. Of course, like any drug, it comes with pitfalls and side effects, some of them quite dangerous. Most of the therapeutics that I&#8217;ve talked about, to date, have had extremely minimal risks. Ivermectin, for treating all manner of ssRNA viral infections, has one of the best safety records of any drug in history, magnified further when compared to the mortality of some such infections; <a href="/__u/veryvirology.substack.com/p/curing-the-incurable-cancer">fenbendazole</a> and menbendazole, with notable but manageable risks to liver health, are nevertheless far safer than what may, often, be guaranteed mortality from all manner of cancers; ascorbic acid, the inimitable Vitamin C, has a very well known safety profile.</p><p>I&#8217;ll tell you right now: <em>one of these is not like the others.</em> 2,4-DNP carries very real risks, when misused or overdosed, up to and including blindness, or a death that is certainly no less unpleasant than a Tylenol overdose. The therapeutic window, which defines the useful range of dosage of a drug between having no effect, at too low a dose, or having deleterious effects, in overdose, is substantially narrower than most drugs available today; and its unique mechanisms, and even the typical psychology of a person using it, also contribute to magnify that risk with anything but the most disciplined, carefully planned and compliant treatment regime.</p><p>Nevertheless, when used correctly and cautiously, the drug can be safe, effective, and truly orders of magnitude more effective than anything else available today. Let&#8217;s get into what it is, how it works, and why, when nothing else will do, 2,4-Dinitrophenol is the undisputed king of weight loss. I&#8217;m surely going to catch some flak for even talking about it, and many of the criticisms that I anticipate will, generally speaking, be well grounded; this is a high voltage, high risk, high reward therapeutic for obesity and weight loss. If you find yourself considering it, I implore you to treat it with the utmost respect and care that it demands, and as with any other therapeutic protocol, to seek medical advice and supervision before and during its use; this article does not substitute for personalized, professional medical advice from a practitioner that knows your circumstances.</p><p>A profound example of the suppression of &#8220;dangerous&#8221; knowledge surfaced quite recently; although we&#8217;ve been talking about the likelihood of cancer, from the mRNA shots, for the better part of five years now, it has remained a minority position. Those who can read the science, or prefer independent journalism over mainstream or establishment publications, knew full well what was coming, whilst the majority were told it was safe. Meanwhile, in an <a href="https://x.com/IamBrookJackson/status/1975743710764601382">expose recently published</a> by Pfizer whistleblower, Brook Jackson, it was revealed that Sen. Ron Johnson, and a few of the so-called leaders of the largely now-captured Covid resistance, also knew all about it, but <em>were explicitly instructed to withhold or slow-walk that information, because it might be scary - <strong>and they complied</strong>.</em> With friends like these&#8230;</p><p>While this is still dangerous, for completely different reasons, the principle stands: knowledge is power, and I would rather empower you to make your own, informed choices<em>.</em> The &#8220;experts&#8221; of the day didn&#8217;t think you could be trusted with these truths.</p><p>Prove them wrong, and be safe.</p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://veryvirology.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">To receive new articles and support this work, please consider becoming a free or paid subscriber. It makes a difference!</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div><h2>What is 2,4-Dinitrophenol?</h2><p>2,4-Dinitrophenol is in a rare class of drugs known as ionophores. Best known in modernity as a chemical pesticide and dye, this unique molecule acts on the inner mitochondrial membrane, the boundary layer between the mitochondrial matrix and the intermembrane space, and disrupts the delicate proton balance across that boundary. All extant life today - <em>everything</em>, from a tomato plant, to a tardigrade, to every single cell in your body and that of literally every living organism today, bar none - depends upon the <em>adenosine <strong>tri</strong>phosphate</em> molecule, ATP, to generate and transport energy within and between cells. Red blood cells carry oxygen; ATP carries energy.</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!T4qg!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fb575378f-5444-45eb-bea4-0064a7497b78_730x511.gif" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!T4qg!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fb575378f-5444-45eb-bea4-0064a7497b78_730x511.gif 424w, /__u/substackcdn.com/image/fetch/$s_!T4qg!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fb575378f-5444-45eb-bea4-0064a7497b78_730x511.gif 848w, /__u/substackcdn.com/image/fetch/$s_!T4qg!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fb575378f-5444-45eb-bea4-0064a7497b78_730x511.gif 1272w, /__u/substackcdn.com/image/fetch/$s_!T4qg!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fb575378f-5444-45eb-bea4-0064a7497b78_730x511.gif 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!T4qg!,w_1456,c_limit,f_auto,q_auto:good,fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fb575378f-5444-45eb-bea4-0064a7497b78_730x511.gif" width="434" height="303.8" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/b575378f-5444-45eb-bea4-0064a7497b78_730x511.gif&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:511,&quot;width&quot;:730,&quot;resizeWidth&quot;:434,&quot;bytes&quot;:null,&quot;alt&quot;:&quot;Animated Molecular Structure of F0F1 ATP Synthase&quot;,&quot;title&quot;:null,&quot;type&quot;:null,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:null,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="Animated Molecular Structure of F0F1 ATP Synthase" title="Animated Molecular Structure of F0F1 ATP Synthase" srcset="/__u/substackcdn.com/image/fetch/$s_!T4qg!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fb575378f-5444-45eb-bea4-0064a7497b78_730x511.gif 424w, /__u/substackcdn.com/image/fetch/$s_!T4qg!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fb575378f-5444-45eb-bea4-0064a7497b78_730x511.gif 848w, /__u/substackcdn.com/image/fetch/$s_!T4qg!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fb575378f-5444-45eb-bea4-0064a7497b78_730x511.gif 1272w, /__u/substackcdn.com/image/fetch/$s_!T4qg!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fb575378f-5444-45eb-bea4-0064a7497b78_730x511.gif 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption">ATP synthase. Note the rotating action. <a href="https://autism.fratnow.com/blog/atp-the-molecular-currency-that-keeps-life-running/">Source</a></figcaption></figure></div><p>If ATP is the gas can, then the mitochondria are the refineries; in one of the best examples of the machine-like nature of our microbiology, the ATP molecule is synthesized, at that boundary, by the aptly named ATP synthase protein. It is an engine in every sense of the word: fuel, the raw materials to produce ATP are injected, it physically spins and rearranges those materials, and energetic ATP molecules are released to power all the functions critical to life, along with a little heat. This process happens millions of times a second in every single metabolizing cell. It is not the only means of producing ATP, but as one of several energy-producing mechanisms, which we evolved over time to preferentially engage, our metabolism heavily depends upon it. The others are, broadly, substrate phosphorylation and anaerobic fermentation, which utilize completely different pathways in different circumstances. Here, we are converting fats to ketones, and then to energy; those pathways will be familiar to those who have investigated or undertaken the keto<em>, </em>as short for <em>ketosis</em>, dietary strategies. That&#8217;s also a valid approach, and one that has yielded excellent results for many people; it&#8217;s also a lot less risky and, of course, a lot less effective, especially in light of the operation of the <a href="https://www.ncbi.nlm.nih.gov/books/NBK592402/">homeostatic weight setpoint</a>, which unlike many other methods, 2,4-DNP does appear to act upon, leading to weight loss <em><strong>that actually persists</strong></em>. </p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!XAoE!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fc204d44e-036f-4198-93ed-efcd3b346261_788x792.jpeg" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!XAoE!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fc204d44e-036f-4198-93ed-efcd3b346261_788x792.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!XAoE!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fc204d44e-036f-4198-93ed-efcd3b346261_788x792.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!XAoE!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fc204d44e-036f-4198-93ed-efcd3b346261_788x792.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!XAoE!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fc204d44e-036f-4198-93ed-efcd3b346261_788x792.jpeg 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!XAoE!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fc204d44e-036f-4198-93ed-efcd3b346261_788x792.jpeg" width="495" height="497.51269035532994" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/c204d44e-036f-4198-93ed-efcd3b346261_788x792.jpeg&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:792,&quot;width&quot;:788,&quot;resizeWidth&quot;:495,&quot;bytes&quot;:null,&quot;alt&quot;:&quot;A Keto Diet for Beginners: The #1 Ketogenic Guide - Diet Doctor&quot;,&quot;title&quot;:null,&quot;type&quot;:null,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:null,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="A Keto Diet for Beginners: The #1 Ketogenic Guide - Diet Doctor" title="A Keto Diet for Beginners: The #1 Ketogenic Guide - Diet Doctor" srcset="/__u/substackcdn.com/image/fetch/$s_!XAoE!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fc204d44e-036f-4198-93ed-efcd3b346261_788x792.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!XAoE!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fc204d44e-036f-4198-93ed-efcd3b346261_788x792.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!XAoE!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fc204d44e-036f-4198-93ed-efcd3b346261_788x792.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!XAoE!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fc204d44e-036f-4198-93ed-efcd3b346261_788x792.jpeg 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption">A safer, slower, but entirely valid alternative is the <em>keto</em> diet. <a href="https://www.dietdoctor.com/low-carb/keto">Source</a></figcaption></figure></div><p>The <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC3360099/">operation</a> of ATP synthase depends on an ionic imbalance between the interior and the exterior of the mitochondrial membrane. It is, almost (but not quite) literally, an electrical circuit; the voltage differential between the inside and the outside of the cell transmits chemical energy across the ATP synthase engine, which consumes that electric current, spins that electric motor, drains the charge outside of the cell, and as with any electrical device, puts off a little waste heat. Proton pumps act as the chargers; consuming energy themselves, albeit less than the synthase protein produces, they maintain that voltage differential by continuously pumping protons, hydrogen ions, which cross the membrane to power that engine, back out of the mitochondrial matrix and into the intermembrane space again, where the cycle repeats. It runs frequently, but not constantly: <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC5553560/">enzymes</a> within the cell, AMP-activated protein kinase (AMPK) specifically, tell the mitochondria when more ATP energy is required, and the mitochondria activates those proteins until that energy demand is met, generating heat and oxidative waste products. The process is called <em><a href="https://www.ncbi.nlm.nih.gov/books/NBK9885/">oxidative phosphorylation</a></em>: that chemo-electric fuel is literally burned, or <em>oxidized</em>, to add a phosphate group to the precursor ADP, <em>adenosine <strong>di</strong>phosphate</em>. If ATP is the gas can when it&#8217;s full, ADP is the very same can, but when it&#8217;s empty; lacking that extra molecule of phosphate, it needs to be refilled, by ATP synthase, for reuse.</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!7NXJ!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Ff000dacb-af4d-431c-b65a-aeef0153915a_1980x1980.jpeg" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!7NXJ!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Ff000dacb-af4d-431c-b65a-aeef0153915a_1980x1980.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!7NXJ!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Ff000dacb-af4d-431c-b65a-aeef0153915a_1980x1980.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!7NXJ!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Ff000dacb-af4d-431c-b65a-aeef0153915a_1980x1980.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!7NXJ!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Ff000dacb-af4d-431c-b65a-aeef0153915a_1980x1980.jpeg 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!7NXJ!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Ff000dacb-af4d-431c-b65a-aeef0153915a_1980x1980.jpeg" width="358" height="358" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/f000dacb-af4d-431c-b65a-aeef0153915a_1980x1980.jpeg&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:1456,&quot;width&quot;:1456,&quot;resizeWidth&quot;:358,&quot;bytes&quot;:null,&quot;alt&quot;:&quot;ATP &amp; ADP - Biological Energy - Biology Online Tutorial&quot;,&quot;title&quot;:null,&quot;type&quot;:null,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:null,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="ATP &amp; ADP - Biological Energy - Biology Online Tutorial" title="ATP &amp; ADP - Biological Energy - Biology Online Tutorial" srcset="/__u/substackcdn.com/image/fetch/$s_!7NXJ!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Ff000dacb-af4d-431c-b65a-aeef0153915a_1980x1980.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!7NXJ!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Ff000dacb-af4d-431c-b65a-aeef0153915a_1980x1980.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!7NXJ!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Ff000dacb-af4d-431c-b65a-aeef0153915a_1980x1980.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!7NXJ!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Ff000dacb-af4d-431c-b65a-aeef0153915a_1980x1980.jpeg 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption">ATP versus ADP. <a href="https://www.biologyonline.com/tutorials/biological-energy-adp-atp">Source</a></figcaption></figure></div><p>DNP takes a sledgehammer to that delicately balanced circuit. In the ordinary course of events, the potential energy in that mitochondrial battery is carefully discharged across ATP synthase, powering that engine. DNP is, effectively, <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC9013436/">a short circuit</a>. It diffuses across that membrane, and provides a path through which those protons can simply cross straight over the membrane. In doing so, they do no useful work, depriving ATP synthase of the energy it needs to operate; if the intermembrane space is the positive terminal, the mitochondrial matrix the negative, and ATP synthase is the controlled, well-oiled engine sitting between them, DNP is a thick strand of copper directly between the terminals, short-circuiting that battery as fast as it can carry those protons across the boundary. If you&#8217;re at all familiar with what happens in a short circuit&#8230;</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!hlGm!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd0f473c0-d7b4-4eb8-b727-c3fd21a62181_968x588.png" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!hlGm!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd0f473c0-d7b4-4eb8-b727-c3fd21a62181_968x588.png 424w, /__u/substackcdn.com/image/fetch/$s_!hlGm!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd0f473c0-d7b4-4eb8-b727-c3fd21a62181_968x588.png 848w, /__u/substackcdn.com/image/fetch/$s_!hlGm!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd0f473c0-d7b4-4eb8-b727-c3fd21a62181_968x588.png 1272w, /__u/substackcdn.com/image/fetch/$s_!hlGm!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd0f473c0-d7b4-4eb8-b727-c3fd21a62181_968x588.png 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!hlGm!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd0f473c0-d7b4-4eb8-b727-c3fd21a62181_968x588.png" width="420" height="255.12396694214877" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/d0f473c0-d7b4-4eb8-b727-c3fd21a62181_968x588.png&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:588,&quot;width&quot;:968,&quot;resizeWidth&quot;:420,&quot;bytes&quot;:798895,&quot;alt&quot;:null,&quot;title&quot;:null,&quot;type&quot;:&quot;image/png&quot;,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:&quot;https://veryvirology.substack.com/i/175750836?img=https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd0f473c0-d7b4-4eb8-b727-c3fd21a62181_968x588.png&quot;,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="" srcset="/__u/substackcdn.com/image/fetch/$s_!hlGm!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd0f473c0-d7b4-4eb8-b727-c3fd21a62181_968x588.png 424w, /__u/substackcdn.com/image/fetch/$s_!hlGm!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd0f473c0-d7b4-4eb8-b727-c3fd21a62181_968x588.png 848w, /__u/substackcdn.com/image/fetch/$s_!hlGm!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd0f473c0-d7b4-4eb8-b727-c3fd21a62181_968x588.png 1272w, /__u/substackcdn.com/image/fetch/$s_!hlGm!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd0f473c0-d7b4-4eb8-b727-c3fd21a62181_968x588.png 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption"><em>It&#8217;ll buff out.</em></figcaption></figure></div><p>&#8230;it applies just as equally here. That potential energy still does work, in the thermodynamic sense, and still directly proportional to the amount of energy being discharged across the membrane; but rather than <em>useful</em> work, just as in a short circuit, that energy is exclusively dissipated as heat, and quite a bit of it, at that.</p><p>That short-circuit has numerous effects. The first, most obvious one, is heating: if you bridge a short circuit, you&#8217;re going to make a very hot wire. Doing so also depletes the energy that&#8217;s available for ATP synthase to do its job, and the proton pumps have to work overtime to recharge that battery; for the same amount of energy that&#8217;s expended across the membrane, far less ATP is actually produced. There is, of course, only so much fuel for those reactions that&#8217;s actually available; even as ATP becomes much more difficult to produce, the cell&#8217;s energy needs don&#8217;t magically disappear. The first and most easily accessible source of energy is sugars, glycogen specifically. They are stored primarily, by volume, in the muscles; glycogen is to ATP as crude oil is to gas. Muscles, the primary site of bioavailable glycogen storage, have two metrics by which they can be judged, being their density, and their volume. Muscles can either grow larger, and in doing so, store more glycogen, which gives them enhanced endurance over time; or, they can grow denser, which increases raw strength. (Or both.) That dichotomy is why the lean martial artist, whilst perhaps not possessed of the stamina of a completely ripped bodybuilder, can nevertheless hit twice as hard, and <a href="https://www.youtube.com/watch?v=G6yAgsl8flc">easily win</a> an arm wrestle against him. This is also one of the fundamental differences between men and women; the fairer sex, generally, develops a less dense musculature.</p><p>As DNP does its work, shuttling protons from the intermembrane space back into the mitochondrial matrix to waste enormous amounts of energy, the raw fuel requirement of that cell skyrockets. The first place from which it will draw that energy is the glycogen stores. This is, obviously, completely non-conducive to weight loss, and as we will see, one of the primary causes of overdose and death in inexperienced or impatient users of this drug. Just as in ketosis, for any effective weight loss to occur, the body must first deplete its most readily available energy source, being that sugary glycogen, before any fat reserves will be tapped. That process can typically take several days, being directly proportional to the amount of glycogen immediately available. Throughout that period, absolutely no noticeable changes or effects will occur.</p><p>The complete lack of any instant result is infamous for frustrating impatient users who, despite having perhaps started at a safe dose, then go on to take much more than a safe dose, hoping to see some effect, and only belatedly, when <em>almost</em> <em>nothing can then be done</em>,<em> </em>realize their tragic error in having exceeded that narrow therapeutic window, as it begins to take effect.</p><p></p><h3>Feeling The Burn</h3><p>Once that period has elapsed, though, it&#8217;s go time. Glycogen stores are depleted, and with every cell in the body screaming for energy, an <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC10844723/">unbridled assault</a> on the body&#8217;s fat reserves commences, by the same method, albeit greatly accelerated, as the <em>keto</em> diet. The first symptom to be noticed, aside from the rise in body temperature, is the extreme tiredness. Glycogen depletion is probably more familiar to you as <em>being tired. </em>If you just ran a marathon, your muscles are going to be tired. Congratulations: one is now, sitting and sweating in an air-conditioned room, because they don&#8217;t have the energy to do anything else, running that marathon, every minute of every day, until the body finally, eventually metabolizes and disposes of that DNP.</p><p>DNP is lipophilic; it binds to fatty acids. This is, of course, a core function of how it operates; cellular membranes are made of lipids, and that lipophilicity is what enables it to diffuse across the cell membranes until it reaches its targets on the mitochondria. It also attaches to lipocytes, those cells of fat that you&#8217;re trying to burn, and is only slowly released into the bloodstream to find a target, and to be metabolized and excreted, over the course of approximately three days. This has an extremely dangerous effect on the undisciplined, inexperienced, or impatient user, and again, mirrors pretty closely the deadly course of a Tylenol overdose; if you overdose today, you&#8217;re not going to know, or feel any different, for at least a few days&#8217; time, and once those three days have passed, the active dose in your system is going to rise, proportionally to dose, and continue to rise for another day or two.</p><p>This is how death by overdose occurs. The DNP that was taken a few days ago is only now, finally, becoming active; even if one realizes their error, and completely ceases taking it, it&#8217;s far too late to make a difference. This might also be a good time to mention that <em><strong>there is no antidote</strong>. </em>Death, by malignant hyperthermia and multiple organ failure, is the standard outcome of an acute overdose; typical cooling measures, such as ice baths, dantrolene, or even intravenous cooling, have very low success rates, regardless of how quickly the overdose is caught or treated. It is, by all accounts, an extremely painful, <a href="https://www.sciencedirect.com/science/article/abs/pii/S0735675719301858">violent</a>, and distressing way to die; unlike an ordinary heat stroke, that extreme, excess heat is being generated from the inside, by every single affected cell, and it&#8217;s simply impossible to reach and cool them all fast enough. In a few, very mild cases, there have been some successes, but as a rule, the vast majority of overdoses will result in a painful death, and that should be the expected result of diverging, for any reason, from a safely, conservatively calculated dosing regime. <em><strong>Overdosing on DNP will be the last mistake you ever make.</strong></em></p><p>Let me repeat that:</p><p></p><blockquote><h4><strong>OVERDOSING ON 2,4-DINITROPHENOL <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC4840695/">WILL</a> <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC11628266/">BE</a> <a href="https://www.sciencedirect.com/science/article/abs/pii/S1752928X21000330">THE</a> <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC6242799/">LAST</a> <a href="https://www.atsjournals.org/doi/10.1513/AnnalsATS.201908-574CC">MISTAKE</a> <a href="https://academic.oup.com/jat/article-pdf/30/3/219/2134093/30-3-219.pdf">YOU</a> <a href="https://www.researchgate.net/publication/381206442_A_Case_of_Fatal_Poisoning_Use_of_2-4_Dinitrophenol_for_Weight_Loss">EVER</a> <a href="https://jamanetwork.com/journals/jama/fullarticle/249195">MAKE</a>.</strong></h4></blockquote><p></p><h3>So, you didn&#8217;t overdose - now what?</h3><p>Congratulations! Now you have a week, maybe two at the outer limits, to enjoy your total exhaustion: as you lay still in bed, or your favorite comfy chair, sweating until the sheets are soaked through (and dyed yellow, but we&#8217;ll get to that one), you are spending every minute of every day running a marathon, the intensity of which is proportional to the dose of DNP that you took and maintained. Avoiding an overdose is just the beginning; now we need to take a closer look at exactly what&#8217;s happening as all that fat and energy is being burned.</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!gC7G!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F63d1f506-a24a-4f8c-a60e-bdf207330c19_1024x807.png" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!gC7G!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F63d1f506-a24a-4f8c-a60e-bdf207330c19_1024x807.png 424w, /__u/substackcdn.com/image/fetch/$s_!gC7G!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F63d1f506-a24a-4f8c-a60e-bdf207330c19_1024x807.png 848w, /__u/substackcdn.com/image/fetch/$s_!gC7G!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F63d1f506-a24a-4f8c-a60e-bdf207330c19_1024x807.png 1272w, /__u/substackcdn.com/image/fetch/$s_!gC7G!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F63d1f506-a24a-4f8c-a60e-bdf207330c19_1024x807.png 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!gC7G!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F63d1f506-a24a-4f8c-a60e-bdf207330c19_1024x807.png" width="306" height="241.154296875" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/63d1f506-a24a-4f8c-a60e-bdf207330c19_1024x807.png&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:807,&quot;width&quot;:1024,&quot;resizeWidth&quot;:306,&quot;bytes&quot;:1660839,&quot;alt&quot;:null,&quot;title&quot;:null,&quot;type&quot;:&quot;image/png&quot;,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:&quot;https://veryvirology.substack.com/i/175750836?img=https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F63d1f506-a24a-4f8c-a60e-bdf207330c19_1024x807.png&quot;,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="" srcset="/__u/substackcdn.com/image/fetch/$s_!gC7G!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F63d1f506-a24a-4f8c-a60e-bdf207330c19_1024x807.png 424w, /__u/substackcdn.com/image/fetch/$s_!gC7G!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F63d1f506-a24a-4f8c-a60e-bdf207330c19_1024x807.png 848w, /__u/substackcdn.com/image/fetch/$s_!gC7G!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F63d1f506-a24a-4f8c-a60e-bdf207330c19_1024x807.png 1272w, /__u/substackcdn.com/image/fetch/$s_!gC7G!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F63d1f506-a24a-4f8c-a60e-bdf207330c19_1024x807.png 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption">A brisk morning run on a bright, sunny day. </figcaption></figure></div><p>You may be familiar with lactic acid. As you exert yourself in the course of ordinary physical activity, lactic acid builds up in your muscles; when it starts to hurt, that might be your sign that it&#8217;s time to take a break; or you can, with great willpower, push through the burn, dream the impossible dream, and finish those 20 push-ups. However, you&#8217;re in luck - you don&#8217;t need a drop of that willpower now! Here&#8217;s to pharmaceutical miracles! No matter what you do, you&#8217;re going to be feeling that burn, and it&#8217;s just going to keep getting worse until you&#8217;re done. So, we need to find another way to deal with that.</p><p>Aside from overdose, the next biggest risk of DNP comes from the overproduction of reactive oxygen species: you might better know them as free radicals. They are produced in the normal course of exertion, and in that <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC7498668/">normal course of exertion</a>, they are produced in a reasonable number that your body can naturally handle; while some people like to take antioxidants as a general health supplement, and they can in fact help to further mitigate the damage they do and the <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC12046069/">visible aging</a> that they cause, they generally aren&#8217;t strictly necessary to live a healthy, normal life.</p><p>However, running a 24-7 marathon is not something that normal people normally do.</p><div class="captioned-image-container"><figure><a class="image-link image2" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!NwQt!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F0b0ea8d8-8c2b-4e71-b622-920e12f24513_220x144.gif" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!NwQt!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F0b0ea8d8-8c2b-4e71-b622-920e12f24513_220x144.gif 424w, /__u/substackcdn.com/image/fetch/$s_!NwQt!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F0b0ea8d8-8c2b-4e71-b622-920e12f24513_220x144.gif 848w, /__u/substackcdn.com/image/fetch/$s_!NwQt!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F0b0ea8d8-8c2b-4e71-b622-920e12f24513_220x144.gif 1272w, /__u/substackcdn.com/image/fetch/$s_!NwQt!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F0b0ea8d8-8c2b-4e71-b622-920e12f24513_220x144.gif 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!NwQt!,w_1456,c_limit,f_auto,q_auto:good,fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F0b0ea8d8-8c2b-4e71-b622-920e12f24513_220x144.gif" width="320" height="209.45454545454547" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/0b0ea8d8-8c2b-4e71-b622-920e12f24513_220x144.gif&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:144,&quot;width&quot;:220,&quot;resizeWidth&quot;:null,&quot;bytes&quot;:null,&quot;alt&quot;:&quot;Run Forrest Run GIFs | Tenor&quot;,&quot;title&quot;:null,&quot;type&quot;:null,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:null,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="Run Forrest Run GIFs | Tenor" title="Run Forrest Run GIFs | Tenor" srcset="/__u/substackcdn.com/image/fetch/$s_!NwQt!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F0b0ea8d8-8c2b-4e71-b622-920e12f24513_220x144.gif 424w, /__u/substackcdn.com/image/fetch/$s_!NwQt!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F0b0ea8d8-8c2b-4e71-b622-920e12f24513_220x144.gif 848w, /__u/substackcdn.com/image/fetch/$s_!NwQt!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F0b0ea8d8-8c2b-4e71-b622-920e12f24513_220x144.gif 1272w, /__u/substackcdn.com/image/fetch/$s_!NwQt!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F0b0ea8d8-8c2b-4e71-b622-920e12f24513_220x144.gif 1456w" sizes="100vw" loading="lazy"></picture><div></div></div></a><figcaption class="image-caption">All day, every day, ready or not. <em>Forrest Gump</em></figcaption></figure></div><p>With inhuman levels of energy (and fat) being burned - dose-dependently, up to or over twice that of an ordinary resting metabolism - inhuman levels of free reactive oxygen species, AKA free radicals, are now being produced in every cell in the body. If you aren&#8217;t familiar with the meaning of the term &#8220;reactive oxygen species,&#8221; put it this way - hydrogen per<em><strong>oxide</strong></em>, also known as a bleach, is one of the more common reactive oxygen species that we see and use every day, and that is exactly what you&#8217;re producing - and the chemical results are about what you might imagine. This over-production of ROS is the primary mechanism by which the second-most common side effect of DNP occurs: <strong>blindness.</strong></p><p><strong>This can and will happen, if not continuously mitigated, with an otherwise safe dose.</strong></p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://veryvirology.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">To receive new articles and support this work, please consider becoming a free or paid subscriber. It makes a difference!</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div><p>However, the news on this front is much better than a simple overdose, and brings us to the second vital element of what is known, at least in the <a href="https://x.com/freedooksX/status/1977145942752280634">bodybuilding community</a>, as a <em>DNP cycle</em>: frequent, heavy doses of <em>unsugared </em>electrolytes and antioxidants.</p><div class="captioned-image-container"><figure><a class="image-link image2" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!QAL7!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F4ba29320-e701-40be-a8eb-0cf652095454_3265x2631.png" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!QAL7!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F4ba29320-e701-40be-a8eb-0cf652095454_3265x2631.png 424w, /__u/substackcdn.com/image/fetch/$s_!QAL7!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F4ba29320-e701-40be-a8eb-0cf652095454_3265x2631.png 848w, /__u/substackcdn.com/image/fetch/$s_!QAL7!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F4ba29320-e701-40be-a8eb-0cf652095454_3265x2631.png 1272w, /__u/substackcdn.com/image/fetch/$s_!QAL7!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F4ba29320-e701-40be-a8eb-0cf652095454_3265x2631.png 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!QAL7!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F4ba29320-e701-40be-a8eb-0cf652095454_3265x2631.png" width="278" height="223.96565934065933" 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/__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F4ba29320-e701-40be-a8eb-0cf652095454_3265x2631.png 424w, /__u/substackcdn.com/image/fetch/$s_!QAL7!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F4ba29320-e701-40be-a8eb-0cf652095454_3265x2631.png 848w, /__u/substackcdn.com/image/fetch/$s_!QAL7!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F4ba29320-e701-40be-a8eb-0cf652095454_3265x2631.png 1272w, /__u/substackcdn.com/image/fetch/$s_!QAL7!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F4ba29320-e701-40be-a8eb-0cf652095454_3265x2631.png 1456w" sizes="100vw" loading="lazy"></picture><div></div></div></a><figcaption class="image-caption">Cataracts, and how to prevent them. <em>Tsao, Y.-T., Wu, W.-C., Chen, K.-J., et al (2022). An assessment of cataract severity based on antioxidant status and ascorbic acid levels in aqueous humor. <strong>Antioxidants, 11</strong>(2), 397. <a href="https://doi.org/10.3390/antiox11020397">https://doi.org/10.3390/antiox11020397</a></em></figcaption></figure></div><p>Reactive oxygen species are just that; unstable, highly reactive oxygen radicals, looking for another chemical with which they can react. Oxygen is everywhere, and reacts with pretty much everything. If you&#8217;ve ever seen a rusty car sitting in a yard, you can see the results: oxygen reacts with iron, iron oxide ensues, and the car is slowly rusted away and destroyed. This also happens to be one of the primary mechanisms of premature aging, and the primary reason that various antioxidant supplements are so popular. However, as you run that race, you burn <em>months</em> of energy for every single day that goes by; free radicals are being produced at inhuman rates, far beyond what the body would normally see, and far in excess the body&#8217;s natural capacity to metabolize them. Unchecked, they will cause extensive tissue damage. While most cells in the body can, to some extent, handle some oxidative stress, the eyes are much less forgiving: especially in women, an abundance of free radicals will oxidize - <em>also known as</em> <em>burning</em> - the lipids and proteins of the lens and the cornea, leading to cataract formation. The inevitable, extensive sweating also causes electrolyte depletion. Most &#8216;sports drinks&#8217; are also heavily sugared, which as we&#8217;ll cover later, is counterindicated; suitable sports supplements, <em>sans</em> sugars, do exist.</p><p>Now, that better news that I mentioned is twofold. Firstly, although it&#8217;s nothing that anybody <em>ever</em> wants to have to go through, that particular form of blindness <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC6139750/">is treatable</a>, with surgical success rates up to 98%; cataract surgery, in which the clouded lens is replaced, is almost as commonplace as plastic surgery now, and in the modern world, so long as you&#8217;ve got insurance or the money to cover it, is quite effective. As that good news goes, though, that&#8217;s decidedly the less good.</p><p>The better news is that <em>it is avoidable.</em> The favorite antioxidant, all over, is &#8230; drum roll please, for the inimitable &#8230; <em>Vitamin C!</em> Ascorbic acid is <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC9598715/">one of the strongest antioxidants</a> known to man, and is broadly systemically bioavailable. Unlike my various other protocols, which call for a specific form of it, being pure, powdered, oral ascorbic acid, generally for reasons of rapid absorption and immunomodulatory function, the precise form in which it&#8217;s taken here does not matter at all. Quantity over quality.</p><p>Glutathione also <a href="https://pubmed.ncbi.nlm.nih.gov/30939721/">serves a similar purpose</a>; as another antioxidant, and in another interesting Tylenol parallel, it too will be consumed by the extensive ROS production, and will benefit from supplementation. While direct oral glutathione is poorly absorbed, the prodrug N-acetylcysteine, or NAC, which should be well known to any who investigated useful Covid therapeutics, enhances its availability.</p><p>So long as there&#8217;s a hefty and continuous stream of antioxidants and electrolytes being made available to the body - and given the quantity that will be passing through the stomach, continuously throughout, a gentler form of Vitamin C, such as sodium ascorbate, is generally preferred - those free radicals will have all the antioxidants in the world with which to harmlessly react, and electrolyte balance can be maintained. Thereafter, instead of a death by a thousand cuts at the hands of a lake of hydrogen peroxide, that reaction forms, after a short chain of further reactions, dehydroascorbic acid (as well as some oxygen and water); that harmless, metabolized end-form of ascorbic acid, which is excreted primarily through the urine (of which one will be producing plenty), almost completely mitigates the presently superhuman metabolism:</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!COOq!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F0e595c3b-af17-4a33-9e02-01c7dc157755_1024x1536.png" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!COOq!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F0e595c3b-af17-4a33-9e02-01c7dc157755_1024x1536.png 424w, /__u/substackcdn.com/image/fetch/$s_!COOq!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F0e595c3b-af17-4a33-9e02-01c7dc157755_1024x1536.png 848w, /__u/substackcdn.com/image/fetch/$s_!COOq!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F0e595c3b-af17-4a33-9e02-01c7dc157755_1024x1536.png 1272w, /__u/substackcdn.com/image/fetch/$s_!COOq!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F0e595c3b-af17-4a33-9e02-01c7dc157755_1024x1536.png 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!COOq!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F0e595c3b-af17-4a33-9e02-01c7dc157755_1024x1536.png" width="238" height="357" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/0e595c3b-af17-4a33-9e02-01c7dc157755_1024x1536.png&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:1536,&quot;width&quot;:1024,&quot;resizeWidth&quot;:238,&quot;bytes&quot;:null,&quot;alt&quot;:null,&quot;title&quot;:null,&quot;type&quot;:null,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:null,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="" srcset="/__u/substackcdn.com/image/fetch/$s_!COOq!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F0e595c3b-af17-4a33-9e02-01c7dc157755_1024x1536.png 424w, /__u/substackcdn.com/image/fetch/$s_!COOq!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F0e595c3b-af17-4a33-9e02-01c7dc157755_1024x1536.png 848w, /__u/substackcdn.com/image/fetch/$s_!COOq!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F0e595c3b-af17-4a33-9e02-01c7dc157755_1024x1536.png 1272w, /__u/substackcdn.com/image/fetch/$s_!COOq!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F0e595c3b-af17-4a33-9e02-01c7dc157755_1024x1536.png 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption">Your desk, sir.</figcaption></figure></div><p>And there you have it! With this knowledge, and your doctor&#8217;s advice and consent -<em>please be aware that <strong>I am not a medical doctor,</strong> <strong>this is not medical advice, and I cannot be responsible for your use or misuse of this dangerous, educational information</strong></em> - one can run a 24 hour, seven to fourteen day, non-stop marathon, from the comfort of their favorite piece of newly yellow, soaking wet furniture, and by the end of it, find themselves <em>up to forty plus pounds lighter.</em></p><p>Yep. That&#8217;s not a typo. <em>Believe</em> me though, as I speak from experience, one will feel every bit as drained and exhausted as though you had been out there on that track. It&#8217;s difficult to really say that it <em>replaces</em> the need for willpower, per-se; whilst having commenced a cycle, given the pharmacokinetics I have described for you above, one will have little choice but to see it through, long past the point at which you&#8217;re tired and would like to go home now, please, you will certainly remember the extraordinary exertion it entails the next time you consider taking it. Having completed one lower-dose, test cycle, I found that it took every bit as much willpower to commence the next one as it would to have gone out on that track. The results, however, are truly in a league of their own. Once upon a time, at 5&#8217;7&#8221;, I was 242 pounds, with a respectable beer and cheeseburger belly; after a single week&#8217;s cycle, <em>and subject to some further nuance I will cover below</em>, I finished that month at a rather less-rounded 198 pounds. That was almost a decade ago now, and even without much in the way of lifestyle change, I never put that weight back on, either; the homeostatic weight setpoint, the consternation of crash dieters since the beginning of time, does appear to reset to wheresoever one lands. I should also note that that was with a relatively high dose; I arguably unwisely skated the edge, but having done the math, I was confident in where it landed, and as it turns out - I&#8217;m still here! - and a decade later, I am still at about that same weight.</p><p></p><h2>The fine print&#8230;</h2><p>That is, in sum, the best and the worst of it. Of course, there is a great deal of care and consideration that must go into avoiding those negative outcomes. We&#8217;ve covered the essentials; I hope that I have struck a good balance between communicating the unparalleled efficacy of 2,4-Dinitrophenol, warning you of the very real risks, and describing - heretofore, <em>in broad strokes</em> - what it takes to avoid them. There are also some unique quirks to its effects, and the progressive timeline of a cycle, that can be, at first, quite confusing and counter-intuitive, that I will go into.</p><p>The legal status of 2,4-DNP across the US, and the world, is quite interesting. Broadly, it has been treated by regulatory regimes not as a drug, but as an agricultural or industrial chemical; for that reason, it sits in a particularly unique grey area. It has been banned as a supplement or drug since 1938; it remains illegal to sell it for medical purposes. However, it is not illegal to <em>buy</em> it, or - <em>usually, with some exceptions, definitely check your local laws -</em> to possess it in small quantities; in larger quantities, far more than are needed for any potential pharmaceutical use, some regulatory regimes treat it as an explosive or a poison. Of course, now that I&#8217;ve published this, that could quite conceivably change any time. For those reasons, reputable, lawful suppliers tend to be international. Ukraine, particularly, has been known for producing and selling it in forms <em>very definitely not intended </em>for human consumption; purity and measurements can vary materially, and with such an unforgivingly narrow therapeutic window, and a near-complete absence of regulatory oversight in &#8220;manufacturing,&#8221; <em>buyer beware</em> when it comes to trusting the label.</p><div class="captioned-image-container"><figure><a class="image-link image2" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!RFmX!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fe2774dcc-15de-43b2-a14e-0dd7fac3419a_1536x1024.png" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!RFmX!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fe2774dcc-15de-43b2-a14e-0dd7fac3419a_1536x1024.png 424w, /__u/substackcdn.com/image/fetch/$s_!RFmX!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fe2774dcc-15de-43b2-a14e-0dd7fac3419a_1536x1024.png 848w, /__u/substackcdn.com/image/fetch/$s_!RFmX!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fe2774dcc-15de-43b2-a14e-0dd7fac3419a_1536x1024.png 1272w, /__u/substackcdn.com/image/fetch/$s_!RFmX!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fe2774dcc-15de-43b2-a14e-0dd7fac3419a_1536x1024.png 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!RFmX!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fe2774dcc-15de-43b2-a14e-0dd7fac3419a_1536x1024.png" width="359" height="239.41552197802199" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/e2774dcc-15de-43b2-a14e-0dd7fac3419a_1536x1024.png&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:971,&quot;width&quot;:1456,&quot;resizeWidth&quot;:359,&quot;bytes&quot;:null,&quot;alt&quot;:null,&quot;title&quot;:null,&quot;type&quot;:null,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:null,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="" srcset="/__u/substackcdn.com/image/fetch/$s_!RFmX!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fe2774dcc-15de-43b2-a14e-0dd7fac3419a_1536x1024.png 424w, /__u/substackcdn.com/image/fetch/$s_!RFmX!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fe2774dcc-15de-43b2-a14e-0dd7fac3419a_1536x1024.png 848w, /__u/substackcdn.com/image/fetch/$s_!RFmX!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fe2774dcc-15de-43b2-a14e-0dd7fac3419a_1536x1024.png 1272w, /__u/substackcdn.com/image/fetch/$s_!RFmX!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fe2774dcc-15de-43b2-a14e-0dd7fac3419a_1536x1024.png 1456w" sizes="100vw" loading="lazy"></picture><div></div></div></a><figcaption class="image-caption"><em>Your quality control, sir. Slava Cocaini.</em></figcaption></figure></div><p>Given that, for the last hundred years, formal scientific research, study or consideration of 2,4-DNP has largely been limited to case studies of overdoses and deaths, the following knowledge of its actual use, derived from the original studies over 100 years ago, has largely been obtained and refined by the trial, and occasional horrific error, of the bodybuilding and weightlifting communities, and of course, my own personal studies and experience. It&#8217;s a relatively thin knowledge base, especially in light of the overflowing wealth of information available on some of the other subjects I have explored, but in my opinion, it is quite sufficient for cautious use.</p><p>The most typical application of 2,4-DNP, beyond angsty, anorexic teenage girls that think they&#8217;re fat, is bodybuilders looking to rapidly cut their fat before a contest; whether to better define their muscular figure, or to sneak in under the line of a lower weight class, the extreme rapidity of its action makes it invaluable to such people looking for an edge. Medicinal use, for the treatment of obesity, tends to be much rarer, but not unheard of. Interestingly, the drug has also served as a <a href="https://www.wearethemighty.com/mighty-history/drug-russians-took-beat-nazis/">Russian secret weapon</a> in their deployment of General Winter; in several wars, Russian conscripts, fighting through the howling European winters with deeply inadequate clothing, were issued low doses of DNP to elevate their metabolisms, keeping them warm as they trudged through the sub-freezing steppes. It was, reportedly, highly effective.</p><p>The dye aspect of it is profound: it is an extremely potent, systemic yellow dye. Urine will take on a characteristic, particularly deep yellow hue, distinct from, and somewhat masking of, dehydration; the ocular sclera, and even the skin, can similarly be affected, which also has the unfortunate effect of mimicking, to some extent, the appearance of jaundice, albeit, except in cases of overdose where it would be the least of one&#8217;s problems, not exhibiting any particular hepatotoxicity. Surfaces, objects and fabrics, if exposed, will be permanently stained upon exposure; as mentioned above, sweat will be an ever present companion throughout a cycle, and similarly carries the dye; while I found that darker colors tended to be unaffected, or at least much less notably so, whites will certainly cease to be, so with white furnishings, clothes or bedsheets, if one would like them to remain so, it is a consideration to be made.</p><p>The process has a built-in time limit: cycles tend to be limited to a week, or up to two at absolute maximum. Beyond that, a temporary tolerance develops; in response to the glaring inefficiencies it produces, more ATP synthase is deployed by cells, the drug is cleared faster, different metabolic pathways take over, and the useful effect is sharply limited.</p><p>2,4-DNP is not metabolized by any of the usual enzymatic drug clearance pathways, such as CYP3A4 or CYP450; it is largely excreted intact, in urine, and of the fraction that is processed, that occurs via glucuronidation and sulfation in the liver, with no known (further) toxic metabolites.</p><p></p><h3>The Don&#8217;ts</h3><p>Heavy exercise during a cycle is generally frowned upon and counterproductive. You wanted to lose serious weight without physical exercise or willpower; you got it, so &#8220;enjoy&#8221; it. Consumption of carbs or sugars - bread, candy, soda - is also a particularly bad idea; beyond the obvious effect of replenishing glycogen stores, which defeats the entire purpose and methodology, people have reported - myself among them - a flash of intense heat upon consumption, above and beyond what&#8217;s already occurring, as those sugars are rapidly metabolized. On top of everything else, you&#8217;re still going on a brief keto diet anyway, too. Have some meat and cheese.</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!Ujkp!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F1d63eaf9-93b4-4098-8bf3-35b542073e3b_1024x1536.png" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!Ujkp!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F1d63eaf9-93b4-4098-8bf3-35b542073e3b_1024x1536.png 424w, /__u/substackcdn.com/image/fetch/$s_!Ujkp!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F1d63eaf9-93b4-4098-8bf3-35b542073e3b_1024x1536.png 848w, /__u/substackcdn.com/image/fetch/$s_!Ujkp!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F1d63eaf9-93b4-4098-8bf3-35b542073e3b_1024x1536.png 1272w, /__u/substackcdn.com/image/fetch/$s_!Ujkp!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F1d63eaf9-93b4-4098-8bf3-35b542073e3b_1024x1536.png 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!Ujkp!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F1d63eaf9-93b4-4098-8bf3-35b542073e3b_1024x1536.png" width="248" height="372" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/1d63eaf9-93b4-4098-8bf3-35b542073e3b_1024x1536.png&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:1536,&quot;width&quot;:1024,&quot;resizeWidth&quot;:248,&quot;bytes&quot;:null,&quot;alt&quot;:null,&quot;title&quot;:null,&quot;type&quot;:null,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:null,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="" srcset="/__u/substackcdn.com/image/fetch/$s_!Ujkp!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F1d63eaf9-93b4-4098-8bf3-35b542073e3b_1024x1536.png 424w, /__u/substackcdn.com/image/fetch/$s_!Ujkp!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F1d63eaf9-93b4-4098-8bf3-35b542073e3b_1024x1536.png 848w, /__u/substackcdn.com/image/fetch/$s_!Ujkp!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F1d63eaf9-93b4-4098-8bf3-35b542073e3b_1024x1536.png 1272w, /__u/substackcdn.com/image/fetch/$s_!Ujkp!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F1d63eaf9-93b4-4098-8bf3-35b542073e3b_1024x1536.png 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption"><em>It&#8217;s delicious!</em></figcaption></figure></div><p><em>Article continues below.</em></p>
      <p>
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   ]]></content:encoded></item><item><title><![CDATA[Trump Pushes Forward With Palantir]]></title><description><![CDATA[Palantir's giant database must be stopped.]]></description><link>https://veryvirology.substack.com/p/trump-pushes-forward-with-palantir</link><guid isPermaLink="false">https://veryvirology.substack.com/p/trump-pushes-forward-with-palantir</guid><dc:creator><![CDATA[Adam Gaertner]]></dc:creator><pubDate>Sun, 08 Jun 2025 02:20:40 GMT</pubDate><enclosure url="https://substack-post-media.s3.amazonaws.com/public/images/80eaf568-0025-4e1d-89d9-f3edd2ecbab1_969x558.png" length="0" type="image/jpeg"/><content:encoded><![CDATA[<p><strong>On May 30th, 2025</strong>, the same day that Elon Musk resigned from the government and came out swinging against Trump and the Big Beautiful Bill, Trump <a href="https://economictimes.indiatimes.com/news/international/us/palantir-to-create-vast-federal-data-platform-tying-together-millions-of-americans-private-records-stock-jumps/articleshow/121521062.cms">announced</a> that the US will partner with Palantir to create a giant, AI-integrated, all-encompassing database on every single American, unifying every piece of data that every government agency ever held about every last one of us, into one convenient repository that every government or hacker on the planet will end up being able to access.</p><p>The US government has long since held vast amounts of data on every American. From ICE to the ATF to the Social Security Admin, to the ubiquitous intercepts of the FBI and NSA, if you put it all together, they would already know just about everything there is to know about you. The only saving grace is that unless you&#8217;re a terrorist, <a href="https://www.youtube.com/watch?v=AJaJGLmUelA&amp;ab_channel=TheDCShorts">Trump supporter</a>, or <a href="https://judiciary.house.gov/media/press-releases/whistleblower-fbi-putting-threat-tags-on-parents-protesting-school-boards">attending school board meetings</a> about DEI, they <em>don&#8217;t</em> put it together (and even then, their <a href="https://www.nbcnews.com/politics/justice-department/new-mexico-teen-convinced-fbi-was-not-threat-carried-school-shooting-rcna25472">radar</a> <a href="https://www.courttv.com/title/despite-being-on-the-fbis-radar-georgia-school-shooting-still-occured/">is</a> <a href="https://www.indystar.com/in-depth/news/investigations/2021/11/11/indianapolis-fedex-shooting-sheila-hole-inadequate-interventions-failed-stop-killings/6237864001/">hit</a> <a href="https://apnews.com/united-states-government-general-news-0d9f50a80c1140c882e947f3d1b28e3c">or</a> <a href="https://www.nytimes.com/2015/07/17/us/chattanooga-tennessee-shooting.html">miss</a>, to put it mildly.)</p><p>Those various pieces of data are held over a hundred different agencies, with a hundred different levels of access control, and while it&#8217;s still far from ideal, that inefficiency, almost alone, has preserved what flapping few tatters remain of the 4th Amendment. Federal agencies are <a href="https://www.justice.gov/opcl/overview-privacy-act-1974-2020-edition/disclosures-third-parties">not supposed to</a> freely share the data they hold on you; it&#8217;s a feature, not a bug.</p><p>Trump is moving to change that. Starting immediately, Trump has engaged Palantir to work on a new system, integrating all of that data and making it available for the <a href="https://bronson.ai/resources/how-palantir-is-revolutionizing-big-data-analytics/">most advanced, AI-powered analytics in the world</a>. This is not just another warrantless government spying program. Thanks to the Patriot Act, and the four subsequent presidencies that have used and expanded those powers, nobody is surprised to learn that they already have all our data, and nothing really changed when they did that: this is <em>using</em> that data, all of it, in the most invasive possible way. Palantir is the world&#8217;s leading defense and intelligence analytics company, and not by a small margin. Most relevantly, from 2022, <a href="https://www.palantir.com/newsroom/press-releases/palantir-announces-new-distinguished-members-to-federal-advisory-board/">with Deborah Birx on the board</a> (<em>since this story broke, they have since <strong><a href="https://web.archive.org/web/20250602204331/https://www.palantir.com/newsroom/press-releases/palantir-announces-new-distinguished-members-to-federal-advisory-board/">deleted that announcement from their website</a>, </strong>but you can still find it on the archives<strong>)</strong></em>, they were <a href="https://www.theregister.com/2025/03/25/palantir_covid_inquiry_comments/">integral creators</a> of various national Covid surveillance and control systems, cornerstones of the totalitarian technocracy the WEF had planned for the Great Reset. The world pushed back, and they were forced to shelve those plans for at least the last couple of years; now, with a new face, a new name, and a new president, they&#8217;re back to finish what they started.</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!WmhM!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F6cfdd536-7ed6-4fea-8982-38797eb535dd_1000x655.jpeg" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!WmhM!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F6cfdd536-7ed6-4fea-8982-38797eb535dd_1000x655.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!WmhM!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F6cfdd536-7ed6-4fea-8982-38797eb535dd_1000x655.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!WmhM!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F6cfdd536-7ed6-4fea-8982-38797eb535dd_1000x655.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!WmhM!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F6cfdd536-7ed6-4fea-8982-38797eb535dd_1000x655.jpeg 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!WmhM!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F6cfdd536-7ed6-4fea-8982-38797eb535dd_1000x655.jpeg" width="438" height="286.89" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/6cfdd536-7ed6-4fea-8982-38797eb535dd_1000x655.jpeg&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:655,&quot;width&quot;:1000,&quot;resizeWidth&quot;:438,&quot;bytes&quot;:null,&quot;alt&quot;:&quot;The COVIDSafe app was designed to help contact tracers. We crunched the  numbers to see what really happened - School of Public Health - University  of Queensland&quot;,&quot;title&quot;:null,&quot;type&quot;:null,&quot;href&quot;:null,&quot;belowTheFold&quot;:false,&quot;topImage&quot;:true,&quot;internalRedirect&quot;:null,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="The COVIDSafe app was designed to help contact tracers. We crunched the  numbers to see what really happened - School of Public Health - University  of Queensland" title="The COVIDSafe app was designed to help contact tracers. We crunched the  numbers to see what really happened - School of Public Health - University  of Queensland" srcset="/__u/substackcdn.com/image/fetch/$s_!WmhM!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F6cfdd536-7ed6-4fea-8982-38797eb535dd_1000x655.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!WmhM!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F6cfdd536-7ed6-4fea-8982-38797eb535dd_1000x655.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!WmhM!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F6cfdd536-7ed6-4fea-8982-38797eb535dd_1000x655.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!WmhM!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F6cfdd536-7ed6-4fea-8982-38797eb535dd_1000x655.jpeg 1456w" sizes="100vw" fetchpriority="high"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption"><em>Take a selfie or we&#8217;re throwing you in prison. <a href="https://www.reuters.com/article/world/australia-launches-controversial-covid-19-tracking-app-as-some-states-start-easi-idUSKCN22806I/">Some got it worse than others</a></em></figcaption></figure></div><p>If this is allowed to come to fruition, the 4th Amendment is dead. Palantir was more or less founded, <a href="https://builtin.com/articles/what-is-palantir">being a CIA creation via their In-Q-Tel investment cutout</a>, to build and operate systems for the US government; one among many, the <a href="https://www.facebook.com/RedactedNewss/videos/the-deep-state-mafia-is-running-both-political-parties-journalist-whitney-webb-r/416218077420761/">Main Core system</a> operated by the NSA, which was designed to detect and classify Americans as potential terrorists, had three million Americans on it as of 2008; that truly pales against the scale of sucking up literally every piece of data, on every person, from every agency of government, and feeding it into a central, AI-enabled database. No government, no corporation, no person in the world should have that much power.</p><p>The lawsuits against DOGE also just laid some notable <a href="https://www.bloomberg.com/news/articles/2025-06-06/supreme-court-gives-doge-access-to-social-security-data">groundwork</a> for allowing this: in a ruling today, SCOTUS affirmed that DOGE, under presidential order, was properly granted access to as much information in the SSA as the President wanted to give them. The scope of that order pales against the scope of what is being granted to Palantir, largely in the fact that it pertains to a single agency, not the entire US government&#8217;s stash of information; but it&#8217;s one more incremental brick in the wall.</p><p>This also comes on the heels of a string of other, less than optimal developments: Moderna&#8217;s latest weapon of genocide <a href="https://investors.modernatx.com/news/news-details/2025/Moderna-Receives-U-S--FDA-Approval-for-COVID-19-Vaccine-mNEXSPIKE/">got the nod</a> from the FDA, despite the promise that no new approvals would happen without <a href="https://www.vaccineadvisor.com/news/rfk-jr-to-change-vaccine-testing-rules/">placebo controlled trials</a>, which would lay bare their deadliness before they could take any more lives; Kash Patel and Pam Bondi have been swallowed whole by the swamp, telling us that <a href="https://www.nbcnews.com/politics/justice-department/dan-bongino-kash-patel-jeffrey-epstein-rcna209871">Epstein did, in fact, kill himself</a>, and giving us <a href="https://abcnews.go.com/US/ag-bondi-faces-heat-white-house-trump-allies/story?id=119435303">one excuse</a> <a href="https://www.bbc.com/news/articles/cyvee9rpdq6o">after another</a>, since they started, as to why they have not released those files yet; the war in Ukraine did not, in fact, end on day one, with Senators <a href="https://apnews.com/article/ukraine-russia-sanctions-graham-blumenthal-b2b9b69f504b8afd064055bb3bf11800">Lindsay Graham and Richard Blumenthal</a> still happily feeding at the trough of bottomless Ukrainian corruption; Elon Musk wisely got out before it swallowed him too, and just <a href="https://www.theguardian.com/us-news/2025/jun/06/donald-trump-elon-musk-meltdown-key-moments-in-the-billionaires-spectacular-split">came out swinging</a> about the &#8220;Big Beautiful Bill&#8221;, <a href="https://www.washingtonpost.com/politics/2025/06/06/epstein-files-trump-musk-controversy-explained/">among other things</a>.</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!mPfj!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F00a494c3-161d-46e4-8b63-b083b3b10682_800x533.jpeg" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!mPfj!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F00a494c3-161d-46e4-8b63-b083b3b10682_800x533.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!mPfj!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F00a494c3-161d-46e4-8b63-b083b3b10682_800x533.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!mPfj!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F00a494c3-161d-46e4-8b63-b083b3b10682_800x533.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!mPfj!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F00a494c3-161d-46e4-8b63-b083b3b10682_800x533.jpeg 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!mPfj!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F00a494c3-161d-46e4-8b63-b083b3b10682_800x533.jpeg" width="442" height="294.4825" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/00a494c3-161d-46e4-8b63-b083b3b10682_800x533.jpeg&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:533,&quot;width&quot;:800,&quot;resizeWidth&quot;:442,&quot;bytes&quot;:null,&quot;alt&quot;:&quot;Graham, Blumenthal Visit to Ukraine, Meet With President Zelenskyy - Press  Releases - United States Senator Lindsey Graham&quot;,&quot;title&quot;:null,&quot;type&quot;:null,&quot;href&quot;:null,&quot;belowTheFold&quot;:false,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:null,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="Graham, Blumenthal Visit to Ukraine, Meet With President Zelenskyy - Press  Releases - United States Senator Lindsey Graham" title="Graham, Blumenthal Visit to Ukraine, Meet With President Zelenskyy - Press  Releases - United States Senator Lindsey Graham" srcset="/__u/substackcdn.com/image/fetch/$s_!mPfj!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F00a494c3-161d-46e4-8b63-b083b3b10682_800x533.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!mPfj!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F00a494c3-161d-46e4-8b63-b083b3b10682_800x533.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!mPfj!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F00a494c3-161d-46e4-8b63-b083b3b10682_800x533.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!mPfj!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F00a494c3-161d-46e4-8b63-b083b3b10682_800x533.jpeg 1456w" sizes="100vw"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption"><em>Most Likely to Start a Nuclear War Award, Class of 2025, colorized. </em><a href="https://www.president.gov.ua/en/news/prezident-proviv-zustrich-z-amerikanskimi-senatorami-lindsi-98165">Source</a></figcaption></figure></div><p>All told, the &#8220;swamp&#8221; appears to be alive and well, albeit short a few <a href="https://nypost.com/2025/03/28/us-news/state-department-shutters-usaid-after-trump-court-victory/">USAID</a> <a href="https://thehill.com/opinion/international/5143798-usaid-slush-fund-dei/">slush funds</a>, and the Great Reset, the WEF&#8217;s march toward the totalitarian techno-dystopia they&#8217;ve been working toward for the last fifty years, continues apace. I was asked, in December of 2024, to submit my resume for a position in the admin, and eventually decided against it; seeing what it&#8217;s doing to the people that came in to &#8220;stand against the deep state,&#8221; I&#8217;m thinking that that was a good decision, costly as it has been.</p><p>The explosion of noise on every other subject, from Epstein to Russia to the day-in day-out headlines on the Trump-Musk feud, is serving well to bury this under a torrent of meaningless distraction. They know that we can stop this, if enough of us speak up, and the threat that this poses to the American people cannot be overstated.</p><p>They couldn&#8217;t quite get there with Covid, and now they&#8217;re trying again.</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!WN63!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F75af537d-5672-461a-b004-fe69d7ccbac7_1600x800.jpeg" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!WN63!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F75af537d-5672-461a-b004-fe69d7ccbac7_1600x800.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!WN63!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F75af537d-5672-461a-b004-fe69d7ccbac7_1600x800.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!WN63!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F75af537d-5672-461a-b004-fe69d7ccbac7_1600x800.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!WN63!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F75af537d-5672-461a-b004-fe69d7ccbac7_1600x800.jpeg 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!WN63!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F75af537d-5672-461a-b004-fe69d7ccbac7_1600x800.jpeg" width="510" height="255" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/75af537d-5672-461a-b004-fe69d7ccbac7_1600x800.jpeg&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:728,&quot;width&quot;:1456,&quot;resizeWidth&quot;:510,&quot;bytes&quot;:null,&quot;alt&quot;:&quot;The Matrix: Cypher's Plot Hole Explained (And Solved)&quot;,&quot;title&quot;:null,&quot;type&quot;:null,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:null,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="The Matrix: Cypher's Plot Hole Explained (And Solved)" title="The Matrix: Cypher's Plot Hole Explained (And Solved)" srcset="/__u/substackcdn.com/image/fetch/$s_!WN63!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F75af537d-5672-461a-b004-fe69d7ccbac7_1600x800.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!WN63!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F75af537d-5672-461a-b004-fe69d7ccbac7_1600x800.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!WN63!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F75af537d-5672-461a-b004-fe69d7ccbac7_1600x800.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!WN63!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F75af537d-5672-461a-b004-fe69d7ccbac7_1600x800.jpeg 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption">I don&#8217;t even see Americans anymore.</figcaption></figure></div><h3>What we know</h3>
      <p>
          <a href="/__u/veryvirology.substack.com/p/trump-pushes-forward-with-palantir">
              Read more
          </a>
      </p>
   ]]></content:encoded></item><item><title><![CDATA[Covid Shots Cause Immunodeficiency]]></title><description><![CDATA[New Yale study finally proves what we've known for years.]]></description><link>https://veryvirology.substack.com/p/covid-shots-cause-immunodeficiency</link><guid isPermaLink="false">https://veryvirology.substack.com/p/covid-shots-cause-immunodeficiency</guid><dc:creator><![CDATA[Adam Gaertner]]></dc:creator><pubDate>Sat, 22 Feb 2025 21:31:28 GMT</pubDate><enclosure url="https://substack-post-media.s3.amazonaws.com/public/images/b6651591-c6f8-4392-9d9c-dd7409fa4f10_1024x768.jpeg" length="0" type="image/jpeg"/><content:encoded><![CDATA[<p>Since 2020, long before the shots were even available, I have been warning that the spike-based vaccines would cause immunodeficiency. Given the fact that the virus itself had been engineered to include HIV proteins on the spike, it was all but a foregone conclusion. Of course, between the din of the progressive propaganda networks treating any criticism of them as heresy, and the lunatics and controlled opposition trying to tell you that viruses themselves don&#8217;t even exist, the truth has long been waiting for its day in the light.</p><p>Well, the science has caught up, and now that truth is finally coming out in a form that <a href="https://www.medrxiv.org/content/10.1101/2025.02.18.25322379v1">cannot be denied any longer</a>. Specifically, progressively mounting deficiencies in CD4 T-cell counts have now been measured - alongside the persistence of spike proteins in the blood, now detected, <a href="https://x.com/Kevin_McKernan/status/1892209592857211262">in a new record</a>, up to 709 days post-vaccination - in 66% of the Covid vaccinees studied here.</p><p>In light of this, the administration is - despite the <a href="https://x.com/MdBreathe/status/1893027918881923330">attacks</a> from a few of the <a href="https://x.com/MdBreathe/status/1891939002212630832">people</a> that found themselves, to their surprise and indignation, not to be part of it - now <a href="https://www.dailymail.co.uk/health/article-14174091/Covid-vaccine-faces-ban-Americans-radical-U-turn-Trump-team.html">moving quickly to completely halt their availability</a>. There&#8217;s a certain bittersweet quality to watching some of that drama; it cost me dearly, but I couldn&#8217;t be happier with some of the people that are, and are not, calling the shots now. It&#8217;s something of an open secret that just about everybody around him these days <a href="https://x.com/NicoleShanahan/status/1892977098580729979">knows exactly what&#8217;s up with the shots</a> - but when your entire public personality has been built around narrative self-promotion, <a href="https://x.com/MdBreathe/status/1882486969772785890">some doors are closed for good</a>. Some chose popularity. Some chose to <a href="https://x.com/drsimonegold/status/1893353047398432935">get it done right</a>. You&#8217;ll never hear from most of the latter.</p><p>I&#8217;ll tell you a secret - now that a little time has passed - <em>Trump likes vaccines!</em> Shocking, I know. The straight up anti-all-vaccines position is a crowd pleaser, it&#8217;ll get you the likes and the follows, the fame and the fortune and the Swiss mountain retreats - but it&#8217;s not going to get you anywhere under a President that remains to this day very proud of having brought those vaccines to market at &#8220;warp speed,&#8221; even as the signs mount that <a href="https://x.com/goddeketal/status/1892723135692067105">maybe it wasn&#8217;t such a good idea</a><em>.</em> There will be <a href="https://x.com/BreannaMorello/status/1893331549786960058">accountability</a>, and there will be <a href="https://x.com/os_gertjan/status/1890135509902717366">justice</a>, but it won&#8217;t be wrought by the glory hounds that care more for the fame and the accolades than they do for the fight. There also remains extremely broad support for vaccines in general, among older people and that silent majority that never spent enough time on social media to see what&#8217;s been happening; if that fight is to be won, it will be won by the hard science that can be understood by all, being presented by unimpeachably neutral scientists. It will take time, and it will take credibility, and RFK&#8217;s brilliant strategy - <em>&#8220;vaccines are great actually, let&#8217;s just make sure they&#8217;re safe (they&#8217;re not)&#8221; </em>- is absolutely incompatible with having pigeonholed oneself into complete inflexibility.<em> </em>I know they&#8217;re not, and you know they&#8217;re not; they tried to derail his nomination by calling him an anti-vaxxer, and seeing as he&#8217;s very well maintained that he&#8217;s not, they failed. With that degree of political acumen heading up HHS, we have a once-in-a-generation chance, and there&#8217;s no room for the showboaters.</p><p>But, for now - let&#8217;s dig into exactly what&#8217;s just been &#8220;discovered&#8221; here, five years of warnings and dismissals, and over a year after the study itself was concluded, later.</p><p></p><h2>The Study</h2><p>The cross&#8208;sectional case&#8211;control <a href="https://www.medrxiv.org/content/10.1101/2025.02.18.25322379v1.full.pdf">study</a> was conducted between December 2022 and November 2023 under the Yale LISTEN framework. 42 individuals reporting chronic post&#8208;vaccination symptoms, and 22 otherwise healthy vaccinated &#8220;controls,&#8221; were enrolled. Notably, the &#8220;healthy&#8221; control group had a median of only 199 days since their last shot, whereas the injured group had been vaccinated around 585 days earlier. Even just on that, we can draw a conclusion: the more time that passes, the more damage is done. As we&#8217;ve already learned, quite some time ago, the production of spike protein does <strong>not</strong> cease, and we now have a new record of continuous production up to <strong>709 days </strong>post-vaccination; it probably declines as infected cells are destroyed over time, but it&#8217;s not going anywhere anytime soon. They&#8217;ve turned billions of their cells into semi-permanent factories that ceaselessly produce billions of microscopic needles for years afterward; now the results are finally being quantified.</p><p>As for the specifics: the injured group had reduced levels of both memory and effector CD4 T-cells, significantly below the expected range; significantly increased TNF&#945;-positive CD8 T-cells, indicating an elevated inflammatory response; lower anti-spike antibody levels, relative to controls; and elevated levels of free, circulating spike protein.</p><p>Interestingly, what isn&#8217;t present is the actual blood counts. The study presents them only as percentages of what would be normally expected (generally in the ~42% range). Depending on the baseline, which isn&#8217;t given, ordinary minimum T-cell counts are around 500 ng/ml; any lower than that and you&#8217;re squarely into AIDS territory. 42% less than that? Putting those raw numbers in the data would be a blazing signpost declaring that they&#8217;ve all got, or will have, AIDS. It still is, but it&#8217;s not presented quite so plainly for a lay reader. Probably would&#8217;ve been tough to pass peer review if they made it that clear.</p><p>There&#8217;s a lot more ancillary data if you care to review it, but the upshot is that their immune systems have been decimated, they&#8217;re not responding as strongly to the spike anymore - which is still present, circulating in the blood and doing damage, years after vaccination, despite all those promises that it would be gone after a few days - and they&#8217;re suffering chronic, debilitating inflammation.</p><p></p><h2>How It Actually Happened</h2><p>So, we know that the vaccines are causing a slow-burn immunodeficiency. A person takes the vaccine, takes a booster or two or five, and months to years later, a substantial proportion of them find themselves with a brand new immunodeficiency. That much has now been proven in black and white. The question remains: why?</p><p>It all starts with a protein called gp-120. This is a protein on the spike of the HIV virus: it enables HIV, alongside CCR5, to interface with the CD4 and CCRX4 receptors on CD4, to infect and begin replicating inside of CD4 immune cells. As I covered in my broad exploration of the immunology <a href="/__u/veryvirology.substack.com/p/igg4-antibody-class-switch-end-of">here</a>, CD4 are the colonels of the immune system&#8217;s army; they send and receive chemical signals, from infected cells, from foreign infections, and from other elements of the immune system, and activate the various localized immune responses. One of the hallmarks of HIV is a steadily declining CD4 count and the virus being detectable inside the cells that are supposed to be guarding against it.</p><p>One of the very first revelations, extremely early in the pandemic, and quickly shut down by Fauci, Birx and Collins&#8217; machinations to discredit and suppress any scientific findings that contradicted their various fairy tales, was that <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC8982992/">the gp-120 protein had been engineered into the SARS-CoV-2 virus</a>. Interestingly, it was missing the other half of what&#8217;s usually necessary for HIV to infect a CD4 cell; the gp-41 protein, which interfaces with the CCR5 receptor and permits a viral infection of the cell, was not included alongside gp-120. The upshot of that is that, rather than infecting the cell - <em>usually</em>, anyhow - the spike protein would simply set off alarm bells in the CD4 cell and cause it to self-immolate. With the activation of that secondary receptor, the cell continues to believe that all is well; <a href="https://pubmed.ncbi.nlm.nih.gov/34913355/">without that interaction</a>, it becomes aware that it is under attack, and <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC9576507/">usually self-destructs</a>. It&#8217;s not 100%; some SARS-CoV-2 infections of CD4, just as occurs in HIV/AIDS, have also been detected and imaged.</p><div class="captioned-image-container"><figure><a class="image-link image2" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!0Q08!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F7abc0c83-edeb-410e-bf7a-dc81f1dd2cff_1000x508.jpeg" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!0Q08!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F7abc0c83-edeb-410e-bf7a-dc81f1dd2cff_1000x508.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!0Q08!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F7abc0c83-edeb-410e-bf7a-dc81f1dd2cff_1000x508.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!0Q08!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F7abc0c83-edeb-410e-bf7a-dc81f1dd2cff_1000x508.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!0Q08!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F7abc0c83-edeb-410e-bf7a-dc81f1dd2cff_1000x508.jpeg 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!0Q08!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F7abc0c83-edeb-410e-bf7a-dc81f1dd2cff_1000x508.jpeg" width="390" height="198.12" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/7abc0c83-edeb-410e-bf7a-dc81f1dd2cff_1000x508.jpeg&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:false,&quot;imageSize&quot;:&quot;normal&quot;,&quot;height&quot;:508,&quot;width&quot;:1000,&quot;resizeWidth&quot;:390,&quot;bytes&quot;:55663,&quot;alt&quot;:null,&quot;title&quot;:null,&quot;type&quot;:&quot;image/jpeg&quot;,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:&quot;https://veryvirology.substack.com/i/157578888?img=https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F7abc0c83-edeb-410e-bf7a-dc81f1dd2cff_1000x508.jpeg&quot;,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="" srcset="/__u/substackcdn.com/image/fetch/$s_!0Q08!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F7abc0c83-edeb-410e-bf7a-dc81f1dd2cff_1000x508.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!0Q08!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F7abc0c83-edeb-410e-bf7a-dc81f1dd2cff_1000x508.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!0Q08!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F7abc0c83-edeb-410e-bf7a-dc81f1dd2cff_1000x508.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!0Q08!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F7abc0c83-edeb-410e-bf7a-dc81f1dd2cff_1000x508.jpeg 1456w" sizes="100vw" loading="lazy"></picture><div></div></div></a><figcaption class="image-caption"><em>CD4+ T-cell infected by SARS-CoV-2, exhibiting RdRp (left) and Spike (right).</em> Brunetti, N. S., Davanzo, G. G., de Moraes, D., et al. (2020). SARS-COV-2 uses CD4 to infect T helper lymphocytes. <a href="https://doi.org/10.1101/2020.09.25.20200329">https://doi.org/10.1101/2020.09.25.20200329</a></figcaption></figure></div><p>SARS-CoV-2, and most enveloped viruses, <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC7832013/">bud out from the surface of the cell</a>, binding and encapsulating the spikes and ssRNA in the process, and taking a little bit of the lipid cell wall with it. This method enables it to reproduce and spread rapidly, without directly killing the cells it occupies. This enables, under the right (wrong) circumstances, a far more persistent infection, as it does not need to destroy every cell it infects in order to spread.</p><p>As I&#8217;m sure you&#8217;re aware, the SARS-CoV-2 virion is coated in spikes. They&#8217;re the mechanism by which it interacts with ACE-2 and other receptors to propagate its infection of the various cells it&#8217;s able to enter. A single virion is tiny; 1000x smaller than a CD4 cell, with dozens of those spikes affixed to its surface. When a single virion interacts with a cell, only one of its spikes is engaged and binds to the receptors; the rest of them, presuming a successful infection occurs, are subsumed into the cell along with the first one, and destroyed by proteases and lysosomes inside the cell. Every engineered gain-of-function addition to the spike is present in both the virus and the vaccine, and thusly, have the same effects, regardless of the form - with the curious exception of every strain from Omicron forward, which lost the most severe of the gain of function insertions, to Bill Gates&#8217; dismay.</p><div class="native-video-embed" data-component-name="VideoPlaceholder" data-attrs="{&quot;mediaUploadId&quot;:&quot;52045d17-520e-4d12-bacf-547753650b37&quot;,&quot;duration&quot;:null}"></div><p>The major difference between the mRNA shots, versus the virus, is that there are trillions of <em>free</em> spikes floating around. With a single virion, you&#8217;ve got <a href="https://www.nature.com/articles/s41586-020-2665-2">dozens</a> of spikes, only one of which will ever interact with anything of relevance. When you turn a billion cells into spike factories, and they eventually fill up, burst and die, and release their spikes, <em>every single one of them is capable of destroying anything it touches.</em> It binds to <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC9779393/">red blood cells</a> and <a href="https://www.mdpi.com/2218-273X/14/3/245">platelets</a>, which can cause the proteinaceous &#8220;clots&#8221; that have frequently been observed in the victims who have later died from them; and they cause <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC10201099/">extensive inflammatory damage to the epithelial linings of blood vessels</a> large and small, which doesn&#8217;t help - picture a wall in a warzone, pockmarked with bullets and shrapnel, and that&#8217;s your blood vessels - and they can single-handedly cause abject chaos and destruction as they encounter and destroy CD4 T-cells.</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!fjtq!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Febe04d10-edc4-4400-8bd4-23dfe8d7b586_4000x3000.jpeg" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!fjtq!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Febe04d10-edc4-4400-8bd4-23dfe8d7b586_4000x3000.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!fjtq!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Febe04d10-edc4-4400-8bd4-23dfe8d7b586_4000x3000.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!fjtq!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Febe04d10-edc4-4400-8bd4-23dfe8d7b586_4000x3000.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!fjtq!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Febe04d10-edc4-4400-8bd4-23dfe8d7b586_4000x3000.jpeg 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!fjtq!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Febe04d10-edc4-4400-8bd4-23dfe8d7b586_4000x3000.jpeg" width="417" height="312.75" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/ebe04d10-edc4-4400-8bd4-23dfe8d7b586_4000x3000.jpeg&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:1092,&quot;width&quot;:1456,&quot;resizeWidth&quot;:417,&quot;bytes&quot;:null,&quot;alt&quot;:null,&quot;title&quot;:null,&quot;type&quot;:null,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:null,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="" srcset="/__u/substackcdn.com/image/fetch/$s_!fjtq!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Febe04d10-edc4-4400-8bd4-23dfe8d7b586_4000x3000.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!fjtq!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Febe04d10-edc4-4400-8bd4-23dfe8d7b586_4000x3000.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!fjtq!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Febe04d10-edc4-4400-8bd4-23dfe8d7b586_4000x3000.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!fjtq!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Febe04d10-edc4-4400-8bd4-23dfe8d7b586_4000x3000.jpeg 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption"><em>Cleanup on aisle everywhere.</em></figcaption></figure></div><p>It has also been proven, several times now, that everything else they said about how the mRNA vaccines work was not true: they <strong>do not stay in the arm</strong>, they <strong>do not quickly - or perhaps at all - cease spike production</strong>, and <strong>even the lipid nanoparticles themselves are devastating </strong>to<strong> <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC7613117/">reproductive function</a>,</strong> <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC9047613/">amongst other things.</a></p><p></p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://veryvirology.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption"><em>To receive new articles and support this work, please consider becoming a free or paid subscriber. It makes a difference!</em></p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div><p></p><h2>A Permanent, Slow-Burn Immunodeficiency</h2><p>So, let&#8217;s connect these dots.</p><ol><li><p>LNP-mRNA shots create continuous, long-term production of free, soluble spike proteins, that permeate the entire body.</p></li><li><p>Those soluble spike proteins contain the same HIV epitope, gp-120, that was engineered into the original SARS-CoV-2 virus;</p></li><li><p>Those soluble spike proteins are thousands of times more dangerous than those attached to the virus itself, simply because they are orders of magnitude more biologically active, not being confined and attached to any one virion.</p></li><li><p>Long-term CD4 deficiency has now been conclusively characterized and proven in vaccine recipients, and not found in unvaccinated or Covid-infected patients.</p></li></ol><p></p><p>What does it mean?</p><p><em>They gave you AIDS.</em> <strong>A</strong>cquired <strong>I</strong>mmuno<strong>d</strong>eficiency <strong>S</strong>yndrome. They have <strong>acquired</strong>, from the vaccine, a <strong>syndrome</strong>, among the symptoms of which is <strong>immunodeficiency.</strong></p><p></p><p>Some of us tried to warn you.</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!s66q!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fc186f202-efc5-40fb-8579-3fc0d028acad_1205x1674.jpeg" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!s66q!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fc186f202-efc5-40fb-8579-3fc0d028acad_1205x1674.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!s66q!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fc186f202-efc5-40fb-8579-3fc0d028acad_1205x1674.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!s66q!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fc186f202-efc5-40fb-8579-3fc0d028acad_1205x1674.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!s66q!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fc186f202-efc5-40fb-8579-3fc0d028acad_1205x1674.jpeg 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!s66q!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fc186f202-efc5-40fb-8579-3fc0d028acad_1205x1674.jpeg" width="298" height="413.9850622406639" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/c186f202-efc5-40fb-8579-3fc0d028acad_1205x1674.jpeg&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:1674,&quot;width&quot;:1205,&quot;resizeWidth&quot;:298,&quot;bytes&quot;:null,&quot;alt&quot;:&quot;Image&quot;,&quot;title&quot;:null,&quot;type&quot;:null,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:null,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="Image" title="Image" srcset="/__u/substackcdn.com/image/fetch/$s_!s66q!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fc186f202-efc5-40fb-8579-3fc0d028acad_1205x1674.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!s66q!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fc186f202-efc5-40fb-8579-3fc0d028acad_1205x1674.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!s66q!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fc186f202-efc5-40fb-8579-3fc0d028acad_1205x1674.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!s66q!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fc186f202-efc5-40fb-8579-3fc0d028acad_1205x1674.jpeg 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption"><em>Dr. Luc Montagnier, rest his soul. He knew.</em></figcaption></figure></div><p></p><h2>So, what can I do?</h2><p>Well, this is where it gets interesting. Typical HIV medications, anti-retrovirals, work by suppressing the replication and proliferation of the HIV virus itself. That&#8217;s really not an option in this case: there is no replicating virus, there is only pseudouridinized mRNA, designed for long-term persistence to resist breakdown by natural cellular mechanisms, engaging with the regular cellular machinery that produces all the other  proteins that are critical to life as we know it. There is no &#8220;off&#8221; button for the ribosomes, and if there were, you would die a very quick death, not unlike radiation poisoning, if you used it.</p><p>You don&#8217;t have HIV. You have <strong>AIDS.</strong> The distinction is very important. An interesting note here is that the tests that are generally in use do not detect the HIV virus itself; some more recent tests check for antibodies, but generally, they check the <a href="https://www.ncbi.nlm.nih.gov/books/NBK513289/">blood volume counts of CD4 T-cells</a>, and an immune count below the critical threshold of 500ng/l is a positive result for AIDS; the lower the count, the more advanced the disease, and the more apparent the symptoms of a slowly failing immune system.</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!BvKs!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F1a3db1d7-bcad-4c48-ba5d-b0a2c9084399_761x269.png" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!BvKs!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F1a3db1d7-bcad-4c48-ba5d-b0a2c9084399_761x269.png 424w, /__u/substackcdn.com/image/fetch/$s_!BvKs!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F1a3db1d7-bcad-4c48-ba5d-b0a2c9084399_761x269.png 848w, /__u/substackcdn.com/image/fetch/$s_!BvKs!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F1a3db1d7-bcad-4c48-ba5d-b0a2c9084399_761x269.png 1272w, /__u/substackcdn.com/image/fetch/$s_!BvKs!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F1a3db1d7-bcad-4c48-ba5d-b0a2c9084399_761x269.png 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!BvKs!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F1a3db1d7-bcad-4c48-ba5d-b0a2c9084399_761x269.png" width="761" height="269" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/1a3db1d7-bcad-4c48-ba5d-b0a2c9084399_761x269.png&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:269,&quot;width&quot;:761,&quot;resizeWidth&quot;:null,&quot;bytes&quot;:35955,&quot;alt&quot;:null,&quot;title&quot;:null,&quot;type&quot;:&quot;image/png&quot;,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:&quot;https://veryvirology.substack.com/i/157578888?img=https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F1a3db1d7-bcad-4c48-ba5d-b0a2c9084399_761x269.png&quot;,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="" srcset="/__u/substackcdn.com/image/fetch/$s_!BvKs!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F1a3db1d7-bcad-4c48-ba5d-b0a2c9084399_761x269.png 424w, /__u/substackcdn.com/image/fetch/$s_!BvKs!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F1a3db1d7-bcad-4c48-ba5d-b0a2c9084399_761x269.png 848w, /__u/substackcdn.com/image/fetch/$s_!BvKs!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F1a3db1d7-bcad-4c48-ba5d-b0a2c9084399_761x269.png 1272w, /__u/substackcdn.com/image/fetch/$s_!BvKs!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F1a3db1d7-bcad-4c48-ba5d-b0a2c9084399_761x269.png 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption">You thought we forgot? Oh, we&#8217;re not going to forget. <a href="https://www.bbc.com/news/world-australia-55269381">Source</a></figcaption></figure></div><p></p><p>While there is no single cure yet - in light of these revelations, this will have to become a high priority for the newly reformed agencies under RFK and HHS - there are several promising approaches, some of which can be used now, some of which will require extensive further research and development.</p><p></p><h4>1. Attack The &#8220;Infected&#8221; Cells</h4><p>The &#8220;vaccine&#8221; works by inserting lipid nanoparticles, or LNPs, into the tissues and bloodstream; much like releasing a soap bubble into a crowd of other soap bubbles, most of the cells in our body also have lipid surface layers, and when the particles encounter a cell, their surfaces merge, enabling the LNP bubble to deposit its mRNA contents into the cell. That mRNA is then processed by the ribosomes, which produce the spike proteins. They then float around the cell, occasionally attacking some of the cell&#8217;s natural defense mechanisms against cancer; some migrate to the surface, where they penetrate and present on the surface. That presents an opportunity.</p>
      <p>
          <a href="/__u/veryvirology.substack.com/p/covid-shots-cause-immunodeficiency">
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   ]]></content:encoded></item><item><title><![CDATA[There Is No White Lung Outbreak]]></title><description><![CDATA[Your children aren't being targeted by another Chinese bioweapon.]]></description><link>https://veryvirology.substack.com/p/there-is-no-white-lung-outbreak</link><guid isPermaLink="false">https://veryvirology.substack.com/p/there-is-no-white-lung-outbreak</guid><dc:creator><![CDATA[Adam Gaertner]]></dc:creator><pubDate>Thu, 30 Nov 2023 22:03:58 GMT</pubDate><enclosure url="https://substack-post-media.s3.amazonaws.com/public/images/916eda61-9ba2-4b44-a2e9-733cbb57e39a_1024x1024.png" length="0" type="image/jpeg"/><content:encoded><![CDATA[<p><strong>BREAKING: <a href="https://twitter.com/ChuckCallesto/status/1730286673806655616">142 cases</a> of &#8220;White Lung Syndrome&#8221; reported in Ohio! Fears of a China-like outbreak grip the nation as the <a href="https://twitter.com/MarioNawfal/status/1730295925912813726">CDC demands clarity from China</a>! <a href="https://thenewamerican.com/news/ohios-pediatric-pneumonia-spike-similar-to-chinas/">Children most affected</a>!</strong></p><p></p><p>It&#8217;s a compelling storyline that has quietly been under development for the last month or so. Pictures of ghost-town Chinese airports, <a href="https://twitter.com/CollinRugg/status/1729187735959949677">crowded Chinese hospitals</a> filled to standing room, pictures of Chinese people dead on the streets, and today, breathless reports of 142 cases of children with walking pneumonia in Ohio, and &#8220;fears&#8221; of another China-like outbreak. The story of some new weaponized pathogen coming out of China is one that we&#8217;re all too familiar with at this point, and the fact that it&#8217;s reportedly, primarily affecting children adds a whole new layer to the scare tactics. So, let&#8217;s take a look at what&#8217;s actually being reported.</p><p></p><h3>Walking Pneumonia</h3><p>The condition is being characterized as walking pneumonia, or &#8220;white lung&#8221;; an infection of the lung that progresses silently, causing pneumonia and lung injury, without any of the usual outward symptoms, such as coughing, fever, et cetera. The responsible pathogen has been, at least tentatively, identified as mycoplasma pneumoniae. The &#8220;142 cases&#8221; being reported are actually the sum of similar such syndromes - a collection of symptoms - with which primarily children have presented to hospitals, <em><a href="https://spectrumnews1.com/oh/cleveland/news/2023/11/30/warren-co--health-district-reports-high-number-of-pediatric-pneumonia-cases">since August</a></em> this year<em>.</em></p><p>That minor fact has been largely omitted from the breathless fearmongering that is suddenly being splashed across Twitter feeds and news headlines. 142 cases, over <em>three months</em>, adds up to about a case and a half per day. That is not what an outbreak of a new, potentially pandemic infectious disease looks like.</p><p>Furthermore, the responsible pathogen being <em>mycoplasma</em> raises several more questions. Mycoplasma is a <a href="https://draxe.com/health/mycoplasma/">commensal bacterium</a>; it is a natural, occasional inhabitant of our human microbiome. With a functional immune system keeping it in check, it&#8217;s no more dangerous than any of the multitude of other bacteria that naturally reside there.</p><p></p><h3>So, what&#8217;s really going on?</h3><p>With &#8220;outbreaks&#8221; being reported in China, <a href="https://www.cidrap.umn.edu/pneumonia/denmark-reports-mycoplasma-pneumonia-epidemic">Denmark</a>, and now Ohio, among others, it&#8217;s sure seeming like somebody is intent on hyping this up. Even a cursory examination of what&#8217;s being reported, though, should be enough to make any thinking person very skeptical of the "new China-like pandemic&#8221; storyline that&#8217;s being reported. It&#8217;s a relatively tiny number of cases, spread over a relatively long period of time, of a bacterial pathogen - not a virus - that is naturally ubiquitous in our environment.</p><p>Presuming that there even is a common factor between these cases - which, given the tiny numbers, is far from certain - I am more inclined to think it&#8217;s yet another long-delayed effect of the Covid vaccines. The spike protein, specifically due to the HIV gp120 protein insertion, has an extremely deleterious effect on the immune system; when it comes into contact with <a href="https://pubmed.ncbi.nlm.nih.gov/20088758/">CD4 immune cells</a>, the <a href="/__u/veryvirology.substack.com/p/igg4-antibody-class-switch-end-of">colonels of the immune system</a> primarily responsible for organizing and directing an immune response, the depletion of which is a hallmark of HIV infection, it causes them to destroy themselves. Considered alongside the long-term persistence of those spikes, due to both their ongoing, long-term production by pseudouridylated and thus persistent mRNA, and the hardiness of the proteins themselves once they have been produced, the people who received &#8220;hot shots,&#8221; being the small percentage of shots containing mRNA that actually remained active and capable of translating spike protein, have been suffering a very slow, gradual decimation of their immune systems over time, as the occasional interactions between spike and CD4 gradually added up to a significant immune deficit.</p><p>That cumulative immune deficit could easily be responsible for this small number of cases. Media has been reporting similarly; of course, rather than the direct and clear impact of the shots, they&#8217;re still trying to ascribe it to lockdowns, Covid itself, isolation, et cetera, even as it&#8217;s been years since any of those measures were having any real impact. To confirm that for sure, we&#8217;d need to see data on the vaccination status of these children that are reporting to hospital.</p><p>I highly doubt that we are going to see that data.</p><p></p><h3>What do we do?</h3><p>At this point? There&#8217;s really nothing that can, or needs to be, done, at least medically speaking. The media coverage is reminiscent of the initial Covid outbreak; perhaps there is going to be an attempt to translate these likely vaccine injuries into another pandemic of fear porn, masking, social distancing, lockdowns, et cetera - perhaps they&#8217;ll even manage to find some way to present the implementation of CBDCs as a vital, pandemic-proofing intervention we all need to keep us safe.</p><p>I&#8217;m skeptical, though. This storyline, despite the gradual development over the last month or so, is far too easily debunked with even a cursory examination, and far too many people are skeptical enough to look a little more closely at the facts before jumping on board with the scare campaign. The ostensible targeting of children is surely going to make it more impactful; perhaps, if not to protect themselves, people might yet be inclined to take their useless &#8220;just in case&#8221; measures to protect their children from what amounts to a wholly imaginary threat. Considering that the bacterium is endemic to our natural microbiome, there is absolutely no benefit to be expected from measures intended to prevent the spread of any disease. It is far, far more likely to be due to individuals&#8217; vaccine-induced immunodeficiencies gradually becoming apparent.</p><p>Nevertheless, the hype and hysteria is ramping up, and there is a growing amount of <a href="https://twitter.com/charliekirk11/status/1730295340593770584">independent media</a> that also seem to be taking it seriously, forecasting that this might be <a href="https://x.com/MikeDonio/status/1730273638362882171?s=20">Disease X</a> or a new Chinese bioweapon. It really doesn&#8217;t take a lot of investigation to determine that it&#8217;s very, very highly unlikely to be anything of the sort. The storyline is, at first glance, quite compelling, though, so I think it is definitely worth pushing back on it at this point. Stop the narrative before it really gets started; just like early treatment for Covid, it&#8217;s a lot easier to deal with it in the nascent inception phase than it is once it gets going.</p><p>If it really is to be the beginning of another push towards masks, social distancing, lockdowns, et cetera, the most important thing we can do at this point is to clearly highlight the facts, which do not indicate a new potential pandemic outbreak, and if the calls for mandates start to come:</p><p></p><p>Do not comply.</p>]]></content:encoded></item><item><title><![CDATA[Watch this space...]]></title><description><![CDATA[Big things are happening, but they're not quite done baking.]]></description><link>https://veryvirology.substack.com/p/watch-this-space</link><guid isPermaLink="false">https://veryvirology.substack.com/p/watch-this-space</guid><dc:creator><![CDATA[Adam Gaertner]]></dc:creator><pubDate>Thu, 19 Oct 2023 03:57:11 GMT</pubDate><enclosure url="https://substack-post-media.s3.amazonaws.com/public/images/2bb6084e-bc0e-4402-87b1-16e5be5e1362_1024x715.png" length="0" type="image/jpeg"/><content:encoded><![CDATA[<p>With the world suddenly on the brink of nuclear annihilation again - what is this, the third or fourth time over the last few years? - I think it&#8217;s safe to say energy isn&#8217;t on too many minds right now. Iran could change that, if they achieve their Middle East-wide oil embargo on Israel and perhaps the rest of the Western world, perhaps. Nevertheless, if we do manage to survive to see through the next six months to a year, the next chapter in my work will be a sprawling, worldwide effort to bring to the people of the world the cheap, simple, and very low-cost energy that we should&#8217;ve had for decades now.</p><p>My goal was originally to end the pandemic - as I&#8217;ve detailed across various other articles, the means to accomplish that has shifted, rather dramatically, from what I thought would originally achieve that - getting the information on the cures we have to the right people - into, as our understanding of just how deep it goes has evolved, a gargantuan, multi-faceted effort to bring down the powers and principalities that have done this to us, and to this day continue to push us forward into their brave new world, wherein you will own nothing, and you will be happy. Energy is a critical pillar upon which that empire is built, and just as with medicine, we have had the knowledge to free the world from their stranglehold on it for a very, very long time. With any luck at all, I intend to bring that to fruition in the near future.</p><p>You can read a little more about it in my pinned thread on Twitter.</p><p>I had intended to be writing primarily about that project this month, but having faced a setback of a couple of weeks, we just aren&#8217;t quite there yet. I will be updating and sending this out in the very near future as we reach our first milestone.</p><p>World War 3 is a strange war indeed.</p><p>In the meantime, if you haven&#8217;t already, I encourage you to read through the small library of publications I have already published. There&#8217;s great info in each and every one of those articles: cancer, autoimmunity, neurological diseases, and some primers &amp; details about the world in which we live that will undoubtedly shed some light on a lot of the strange circumstances and events of late.</p><p>Thank you for your support. It is deeply appreciated, and it is only your support that enables my family and I to do all that we do. Your $7 means more than you know to us.</p><p>Check back soon!</p>]]></content:encoded></item><item><title><![CDATA[Curing the Incurable: Autoimmunity]]></title><description><![CDATA[Vaccine injured, take heart: there's hope.]]></description><link>https://veryvirology.substack.com/p/curing-the-incurable-autoimmunity</link><guid isPermaLink="false">https://veryvirology.substack.com/p/curing-the-incurable-autoimmunity</guid><dc:creator><![CDATA[Adam Gaertner]]></dc:creator><pubDate>Mon, 18 Sep 2023 02:59:34 GMT</pubDate><enclosure url="https://substack-post-media.s3.amazonaws.com/public/images/5067a898-bf04-41cb-91c6-84269692827f_812x810.png" length="0" type="image/jpeg"/><content:encoded><![CDATA[<p>One of the most insidious &#8220;side effects&#8221; of vaccine injury, amongst the many and varied other causes, are autoimmune disorders. Everything from <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609433/">autoimmune myocarditis</a>, to psoriasis, to meat allergies <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452663/">caused by the Lone Star Tick</a>, can be traced to disorderly function of the immune system: a protein, be it an endogenous component of the body as in autoimmune disorders, or an otherwise harmless item such as nuts or fruit, the immune system determines that it is a danger to the body, develops B-cell immunity against it, and produces a damaging inflammatory response wherever it is found.</p><p>Until now, there have been <em>very</em> limited options for permanent remediation of these disorders. Once the body has developed immunity against any given protein, the only realistic hope of mitigating the inflammatory disorders thusly caused has been one of two bad choices. In one approach, <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044416/">the IgG4 route is exploited</a>: in a strategy most well known for its application in allergy shots, the immune system is continually exposed to the offending protein. As covered in my <a href="https://veryvirology.stubstack.net/p/igg4-antibody-class-switch-end-of">article on IgG4</a> - albeit from the perspective of the situation where an IgG4 response is <em>decidedly</em> dangerous and unwanted - such continual exposure to the antigen eventually causes the body to progress through the various classes of immune response it is able to offer, until it eventually decides that the protein is harmless after all, and settles on an IgG4 response. This causes IgG4 antibodies to be produced in response to the antigen, shutting down the immune response, and alleviating the inflammatory response. This comes with the downside of having to endure a prolonged, dangerous and unpleasant immune response until that IgG4 switch is eventually accomplished.</p><p>The second option is akin to going after a fly with a bazooka: anti-rejection drugs, such as tacrolimus, can be<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324909/"> used to shut down large swathes of the entire immune system</a>. This is obviously a generally bad idea, as it leaves the patient incredibly vulnerable to any <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2710057/">opportunistic pathogen</a> that might appreciate a defenseless host in which to replicate. This approach is most frequently used, as the name of this class of drugs may suggest, to prevent rejection of transplanted organs; the foreign organ, not having been naturally grown from the host&#8217;s own DNA or comprised of their own tissues, sets off the alarm bells, as aggressively as any infection might. While it is a vital and necessary step in preventing rejection of transplanted organs, the downsides are pretty much as you might expect, essentially leaving the patient with deliberately induced AIDS and dependent on a plethora of pharmaceuticals for survival, possibly and occasionally for life.</p><p>A new breakthrough offers us a third, far better option. Rather than forcing a patient to endure a long-term inflammatory response, or deliberately inducing what might as well be AIDS, a new technique now allows doctors to precisely target a specific immune response, against a specific protein, disabling just that particular response. Discussed in <a href="https://www.nature.com/articles/s41551-023-01086-2">this paper</a>, this represents a major breakthrough.</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!oeu6!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd90193ba-6dca-4240-938b-2cd6281d5742_4415x2513.png" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!oeu6!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd90193ba-6dca-4240-938b-2cd6281d5742_4415x2513.png 424w, /__u/substackcdn.com/image/fetch/$s_!oeu6!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd90193ba-6dca-4240-938b-2cd6281d5742_4415x2513.png 848w, /__u/substackcdn.com/image/fetch/$s_!oeu6!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd90193ba-6dca-4240-938b-2cd6281d5742_4415x2513.png 1272w, /__u/substackcdn.com/image/fetch/$s_!oeu6!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd90193ba-6dca-4240-938b-2cd6281d5742_4415x2513.png 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!oeu6!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd90193ba-6dca-4240-938b-2cd6281d5742_4415x2513.png" width="599" height="341.051510989011" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/d90193ba-6dca-4240-938b-2cd6281d5742_4415x2513.png&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:829,&quot;width&quot;:1456,&quot;resizeWidth&quot;:599,&quot;bytes&quot;:null,&quot;alt&quot;:&quot;IJMS | Free Full-Text | B7-H3/CD276 Inhibitors: Is There Room for the  Treatment of Metastatic Non-Small Cell Lung Cancer?&quot;,&quot;title&quot;:null,&quot;type&quot;:null,&quot;href&quot;:null,&quot;belowTheFold&quot;:false,&quot;topImage&quot;:true,&quot;internalRedirect&quot;:null,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="IJMS | Free Full-Text | B7-H3/CD276 Inhibitors: Is There Room for the  Treatment of Metastatic Non-Small Cell Lung Cancer?" title="IJMS | Free Full-Text | B7-H3/CD276 Inhibitors: Is There Room for the  Treatment of Metastatic Non-Small Cell Lung Cancer?" srcset="/__u/substackcdn.com/image/fetch/$s_!oeu6!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd90193ba-6dca-4240-938b-2cd6281d5742_4415x2513.png 424w, /__u/substackcdn.com/image/fetch/$s_!oeu6!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd90193ba-6dca-4240-938b-2cd6281d5742_4415x2513.png 848w, /__u/substackcdn.com/image/fetch/$s_!oeu6!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd90193ba-6dca-4240-938b-2cd6281d5742_4415x2513.png 1272w, /__u/substackcdn.com/image/fetch/$s_!oeu6!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fd90193ba-6dca-4240-938b-2cd6281d5742_4415x2513.png 1456w" sizes="100vw" fetchpriority="high"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption">B7-H3 (CD276): Multiple functions. <em>Malapelle, U., Parente, P., Pepe, F., Di Micco, M. C., Russo, A., Clemente, C., Graziano, P., &amp; Rossi, A. (2022). B7-H3/CD276 inhibitors: Is there room for the treatment of metastatic non-small cell lung cancer? International Journal of Molecular Sciences, 23(24), 16077. <a href="https://doi.org/10.3390/ijms232416077">https://doi.org/10.3390/ijms232416077</a></em></figcaption></figure></div><p>For those who are suffering from any of the myriad of autoimmune disorders induced by the mRNA vaccines - many of which are primarily due to the fact that the furin cleavage site on the spike, being produced within a cell by that cell&#8217;s own machinery, enables the spike to protrude through the cell membrane, and thusly cause the cell, and every other cell like it, to be recognized and attacked as a foreign body - this offers a major, and frankly unexpected, ray of hope. Utilizing methods that are usually viewed as problematic - this particular method of immunomodulation is <a href="https://molecular-cancer.biomedcentral.com/articles/10.1186/s12943-023-01751-9">usually seen in cancer,</a> wherein tumor cells will activate the targeted receptors to mitigate an immune attack - if a specific autoreactive antibody can be identified to be the root etiology of a patient&#8217;s autoimmune disorder, then this method will allow a therapeutic treatment of that condition, without the non-specific, fly-with-a-bazooka, side-effect heavy approach that necessarily, until now, characterizes the typical treatment regimens. It is also unlikely to create a permanent dependence on the therapy. Quite the opposite, in fact: the authors have noted that the exploitation of this pathway has been observed to successfully induce immune tolerance to the targeted response, permanently shutting it down.</p><p>Insofar as autoimmune disease goes, that would constitute what they call a <strong>cure</strong>.</p><p>Take heart, and make sure that victims of vaccine injuries are made aware of this. This could save <em>a lot</em> of lives, and dramatically improve quality of life for others. The implications go far beyond just vaccine injury, too: everything from peanut allergies to congenital autoimmune disorders could conceivably be cured by this development.</p><p>The Singularity rolls on!</p><p></p><h3>How It Works</h3><p>The actual mechanics of how the therapy achieves this miraculous result are quite intriguing, and explaining them will take another brief detour into the weeds of immunology. If you haven&#8217;t already done so, I highly recommend reading <a href="https://veryvirology.stubstack.net/p/igg4-antibody-class-switch-end-of">this article</a> first, for a broad primer on the basic tenets of immunology.</p>
      <p>
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   ]]></content:encoded></item><item><title><![CDATA[We're Not Doing This Again]]></title><description><![CDATA[Masks are worthless. Stop trying to mandate them.]]></description><link>https://veryvirology.substack.com/p/were-not-doing-this-again</link><guid isPermaLink="false">https://veryvirology.substack.com/p/were-not-doing-this-again</guid><dc:creator><![CDATA[Adam Gaertner]]></dc:creator><pubDate>Thu, 17 Aug 2023 02:36:34 GMT</pubDate><enclosure url="https://substack-post-media.s3.amazonaws.com/public/images/5eecaa83-a840-4ca0-a17a-572c30180bd4_1024x1024.png" length="0" type="image/jpeg"/><content:encoded><![CDATA[<p>Masks, and mask mandates, were never about anybody&#8217;s safety. Almost four years after the beginning of the pandemic, there is still very little evidence to suggest they offer even the slightest protection against covid infection. For a time, the mantra of &#8220;my mask protects you, your mask protects me&#8221; won out; not knowing any better, and faithfully believing in the guidance of our mind-blowingly corrupt and dishonest public health officials, it became a simple gesture of good manners to wear them.</p><p>Over time, it became much clearer what they really represent: compliance. You&#8217;re <em>supposed</em> to know that they don&#8217;t actually protect you. From Fauci&#8217;s &#8220;<a href="https://slate.com/technology/2021/07/noble-lies-covid-fauci-cdc-masks.html">noble lies</a>,&#8221; to the nonsensical restaurant requirements, and the eventual political polarization that developed concerning them, there was deliberately stoked controversy from the very beginning. For every other medico-scientific aspect of this pandemic - from the vaccines, to <a href="https://www.science.org/content/article/very-very-bad-look-remdesivir-first-fda-approved-covid-19-drug">Remdesivir</a> and <a href="https://apnews.com/article/covid-science-health-seniors-d8f6af66517054aae7fb27d1ecc6df66">Paxlovid</a>, to actually useful treatments like <a href="https://twitter.com/veryvirology/status/1613727157863469057">ivermectin</a> and hydroxychloroquine - the scientific fraud machine worked overtime to produce a multitude of bogus, falsified, yet superficially convincing studies that media, influencers, officials and politicians could use to convince you; when it comes to masks, &#8220;The Science&#8221; is still awfully light, and the studies that have been published either <a href="https://www.fiercehealthcare.com/providers/do-masks-really-protect-against-covid-19-meta-analysis-authors-want-see-more-evidence">clearly show they have no effect</a>, or are unconvincing statistical <a href="https://reason.com/2022/02/07/that-study-of-face-masks-does-not-show-what-the-cdc-claims/">misrepresentations</a>. Now, as primary season heats up, and Trump indictments fall like rain, <a href="https://www.dailymail.co.uk/health/article-12408505/Here-comes-real-deal-Scientists-raise-alarm-new-Covid-variant-call-return-face-masks.html">a new Covid variant is being talked up, and &#8220;calls&#8221; for mask mandates are rising again</a>.</p><p>Why now? What&#8217;s the goal?</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!6O7p!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F846c51cf-8ebd-450d-a80b-44f5f12fc99e_828x662.jpeg" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!6O7p!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F846c51cf-8ebd-450d-a80b-44f5f12fc99e_828x662.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!6O7p!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F846c51cf-8ebd-450d-a80b-44f5f12fc99e_828x662.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!6O7p!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F846c51cf-8ebd-450d-a80b-44f5f12fc99e_828x662.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!6O7p!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F846c51cf-8ebd-450d-a80b-44f5f12fc99e_828x662.jpeg 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!6O7p!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F846c51cf-8ebd-450d-a80b-44f5f12fc99e_828x662.jpeg" width="357" height="285.42753623188406" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/846c51cf-8ebd-450d-a80b-44f5f12fc99e_828x662.jpeg&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:662,&quot;width&quot;:828,&quot;resizeWidth&quot;:357,&quot;bytes&quot;:null,&quot;alt&quot;:&quot;Michael Shermer (@michaelshermer) / X&quot;,&quot;title&quot;:null,&quot;type&quot;:null,&quot;href&quot;:null,&quot;belowTheFold&quot;:false,&quot;topImage&quot;:true,&quot;internalRedirect&quot;:null,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="Michael Shermer (@michaelshermer) / X" title="Michael Shermer (@michaelshermer) / X" srcset="/__u/substackcdn.com/image/fetch/$s_!6O7p!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F846c51cf-8ebd-450d-a80b-44f5f12fc99e_828x662.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!6O7p!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F846c51cf-8ebd-450d-a80b-44f5f12fc99e_828x662.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!6O7p!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F846c51cf-8ebd-450d-a80b-44f5f12fc99e_828x662.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!6O7p!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F846c51cf-8ebd-450d-a80b-44f5f12fc99e_828x662.jpeg 1456w" sizes="100vw" fetchpriority="high"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption"><a href="https://nypost.com/2022/09/20/fauci-mocked-ass-backwards-diners-for-removing-masks-at-table/">Fauci is laughing at you.</a></figcaption></figure></div><p></p><h3>The Purpose Of Propaganda</h3><p>If you&#8217;ve been following events at all - and since you&#8217;re reading this, I&#8217;m going to presume you&#8217;re well and truly up to date - you should be well aware that we are in the midst of a Marxist revolution, both in the US and across the Western world. They are, rather unimaginatively, still fairly closely following the playbook written by the Bolsheviks, from the Russian Revolution in 1917. A crucial element of implementing this new tyranny is conditioning: the conditioning of their prospective subjects to mindlessly follow their orders, no matter how absurd, demeaning, or self-defeating.</p><p>There are numerous prongs of this attack on the collective integrity of the people. Transgenderism is a major one; not only have they caused <a href="https://www.axios.com/2022/02/17/lgbtq-generation-z-gallup">~20% of Gen Z to identify as some manner of LGB/T</a>, dramatically impacting overall fertility, in line with the kitchen-sink depopulation efforts, but the conditioning is forceful: <em>men are women, women are men, 2+2=5, and if you don&#8217;t say you agree, you&#8217;re a heartless bigot.</em></p><p>The purpose of communist propaganda is not to persuade, convince, or inform. The purpose of their propaganda is to humiliate and degrade you; to turn you into a liar, repeating and endorsing things that you know to be untrue, and in doing so, to break down your moral character, to lessen your righteousness; to degrade your ability to reject and call out immorality and evil. Let he that is without sin cast the first stone; if everybody is sinning, then nobody will be casting stones, and their evil can carry on unmolested and unchecked. Turning you into a liar degrades your ability and your standing to oppose immorality of all kinds; you know that it&#8217;s wrong, you know that it&#8217;s harmful, but you go along with it, you endorse the Big Lie, because the consequences of opposing it appear to be too great. Needless to say, the consequences of failing to oppose it are far, far worse - but you don&#8217;t see those yet.</p><p>The &#8220;civic duty&#8221; to Wear A Mask was implemented, originally, through both propaganda and, subsequently, peer pressure; and in a solid win for humanity, it was largely defeated in much the same way. Maskers became the butt of the joke everywhere, and gradually, the vast majority of the people in the grocery store ceased to wear them, the workplace mandates were rescinded, and the &#8220;new normal&#8221; was broadly rejected. Point and laugh was the generally accepted M.O., and it worked. Captured institutions, and the occasional die-hard, continued to insist on them; but the idea of masking has been generally, widely discredited as a useful or moral act.</p><p>Now, years later, we&#8217;re hearing that the &#8220;experts&#8221; are insisting on them again. The last variant didn&#8217;t spur such calls; nor did the ones before; but this one, for no particular reason, has the &#8220;experts&#8221; riled up and calling for ubiquitous masking again.</p><p>Again, we ask - why?</p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://veryvirology.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">To receive new articles and support this work, please consider becoming a free or paid subscriber. It makes a difference!</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div><h3>Another Cycle Begins</h3><p>The process of conditioning is fairly straightforward: gradually dial up the heat, until you run into resistance. Once you&#8217;ve pushed as far as you can go, and the resistance starts to materialize in force, back down; repeal the mandates, soften the requirements, allow some of the challenges to see victory; let the people feel like their complaints have been heard, and the tyranny is going to stop now. Once the resistance has settled down, kick it back into gear again, and this time go a little further, a little faster, and see where the new boundary really lies. Winnow and exhaust the capacity and willingness to resist, fine-tune the propaganda and enforcement, and keep on pushing. Without compliance, they have nothing; they need to make you feel powerless, because you have all the power. Only you can decide to surrender it; only by giving in will you do so.</p><p>We have had a fairly long period of softening; cases being won, mandates largely becoming a relic of the past, loosening censorship, and generally moving forward from the pandemic onto more pressing things, like standing with the Ukrainian Fourth Reich and sacrificing livestock to the weather gods. One almost could&#8217;ve imagined that they were done with the pandemic. Sadly, it just ain&#8217;t so. Neither Ukrainians nor cow farts give the ballot counters any excuse to keep observers 50 feet away. Until and unless we fully eradicate either the Covid infection, or the communist infection - or both! - it will continued to be used as a cudgel and a tool of election fraud. We are now in the opening stages of ramping the heat back up again - unless the resistance is fierce, united and ubiquitous, it&#8217;s going to get incrementally more draconian every time. Fifteen minute cities, better known historically as ghettos, and a general prerequisite for and precursor to open genocide, are the endgame insofar as these restrictions go. With everything they&#8217;ve been throwing at Trump having utterly failed to budge his support, they&#8217;re going to have to pull something nasty, and they need to know how badly we&#8217;re going to react; ramping up the panic around election time will also give them a great excuse to permanently solidify the permissive, fraud-enabling rules around voting and ballot counting.</p><p>Subjugating a country so deeply rooted in personal liberty and freedom was never going to be easy. Having largely completed the process of institutional capture, they are again stretching their wings; the rule of law is becoming increasingly weakened, be it through rampant unpunished petty crime, the absurd, lawless indictments of Trump and his circle, or the total failure to hold the Bidens accountable for their broad-daylight corruption; the criminality and corruption is heating up, and with it, the people are again beginning to push back. The mandates have <em>absolutely nothing</em> to do with anybody&#8217;s safety or well-being. They are a purely political tool, a cudgel, with which they can again and again assault your sense of reality, your integrity, and simultaneously both assess, and hopefully degrade, your capacity for resistance.</p><p>If they can make you comply with a mask mandate, when you know full well that it serves absolutely no beneficial purpose, what manner of meaningful resistance do you possibly think you can offer against the wholesale theft of a country and the persecution of its rightful, twice-elected President?</p><p>They aren&#8217;t blind; they can see that they&#8217;re poking a hornet&#8217;s nest with these nakedly political, unjust prosecutions. What they really need to know right now is how far they can push the envelope. Has the program of demoralization worked? How significantly, how completely has it worked? How many people still believe that the masks do anything, versus how many are complying anyway and wearing them?</p><p>The answer to that question is going to inform just how hard they push the envelope over the next year. If they find that there is still broad compliance - particularly alongside simultaneous, widespread knowledge that they do nothing - that right there is a blinking green light to continue and accelerate the effort to break apart this country, and consign us all to a Marxist, WEF-dominated hellscape, from which there will be no peaceful escape.</p><p>Maybe you ascribe to accelerationism. Personally, I don&#8217;t; especially given their incredibly lackluster geopolitical performance of late, with alliances and vassal states falling and failing left and right, time is emphatically not on their side; the longer it takes, the slower it goes, and the more resistance they meet, the likelier that the whole house of cards will collapse before they manage to fully consolidate their power. We are coming into a crucial, historical period of time; the events of the next few years will shape the century to come. What that looks like depends wholly and solely on you.</p><p></p><p><strong>Do not comply.</strong></p><p></p><h2>How?</h2><p>Of course, propaganda and peer pressure isn&#8217;t the only tool being used to generate compliance. The biggest ones are the workplace and college mandates; when long-pursued careers, livelihoods, and hard-earned educational achievements are directly threatened, the threat becomes much more immediate and personal than any abstract concept of what <em>might</em> happen to the country at large in the future, and standing up against it comes with real, quantifiable, potentially life-destroying risks. Over the last few years, those threats were used to enforce compliance with the vaccines; years later, the true experts, warning about blood clots, heart diseases, strokes and sudden death, and berated as quacks and conspiracy theorists, have been proven correct. All-cause excess mortality is far above normal and continuously rising; sudden deaths of celebrities, newscasters, sports players at all levels, and friends, family and colleagues are a regular and ongoing event.</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!bVkx!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F3cf4db4c-35cd-4baf-9766-d5b5f54faba6_1074x1005.jpeg" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!bVkx!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F3cf4db4c-35cd-4baf-9766-d5b5f54faba6_1074x1005.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!bVkx!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F3cf4db4c-35cd-4baf-9766-d5b5f54faba6_1074x1005.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!bVkx!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F3cf4db4c-35cd-4baf-9766-d5b5f54faba6_1074x1005.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!bVkx!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F3cf4db4c-35cd-4baf-9766-d5b5f54faba6_1074x1005.jpeg 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!bVkx!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F3cf4db4c-35cd-4baf-9766-d5b5f54faba6_1074x1005.jpeg" width="581" height="543.6731843575419" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/3cf4db4c-35cd-4baf-9766-d5b5f54faba6_1074x1005.jpeg&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:1005,&quot;width&quot;:1074,&quot;resizeWidth&quot;:581,&quot;bytes&quot;:null,&quot;alt&quot;:&quot;Image&quot;,&quot;title&quot;:null,&quot;type&quot;:null,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:null,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="Image" title="Image" srcset="/__u/substackcdn.com/image/fetch/$s_!bVkx!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F3cf4db4c-35cd-4baf-9766-d5b5f54faba6_1074x1005.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!bVkx!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F3cf4db4c-35cd-4baf-9766-d5b5f54faba6_1074x1005.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!bVkx!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F3cf4db4c-35cd-4baf-9766-d5b5f54faba6_1074x1005.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!bVkx!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F3cf4db4c-35cd-4baf-9766-d5b5f54faba6_1074x1005.jpeg 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption">Nothing to see here&#8230; <a href="https://twitter.com/USMortality/status/1690544651625996288/">Source</a></figcaption></figure></div><p>Of course, the masks don&#8217;t pose <em>quite</em> that level of danger. They are dangerous, nonetheless; for one, <a href="https://link.springer.com/article/10.1007/s11356-022-24702-1">plastic particulate matter</a> is <a href="https://www.koreabiomed.com/news/articleView.html?idxno=20301">lodging in wearers&#8217; lungs</a>, likely to eventually cause any of a variety of respiratory diseases; masks produced in horribly unhygenic conditions, and by our geopolitical enemies in China, are also frequently contaminated with everything from fecal matter to graphene fibers, which have absolutely no business being anywhere near your mouth or lungs. Any way you slice it though, unless there are already extenuating respiratory conditions, it&#8217;s still difficult to argue that a mask is anywhere near as dangerous as the Russian Roulette that is the shots.</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!_h2J!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F55c1573f-dacd-48c4-997c-9daba3d2ba15_1280x720.jpeg" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!_h2J!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F55c1573f-dacd-48c4-997c-9daba3d2ba15_1280x720.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!_h2J!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F55c1573f-dacd-48c4-997c-9daba3d2ba15_1280x720.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!_h2J!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F55c1573f-dacd-48c4-997c-9daba3d2ba15_1280x720.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!_h2J!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F55c1573f-dacd-48c4-997c-9daba3d2ba15_1280x720.jpeg 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!_h2J!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F55c1573f-dacd-48c4-997c-9daba3d2ba15_1280x720.jpeg" width="479" height="269.4375" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/55c1573f-dacd-48c4-997c-9daba3d2ba15_1280x720.jpeg&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:720,&quot;width&quot;:1280,&quot;resizeWidth&quot;:479,&quot;bytes&quot;:null,&quot;alt&quot;:&quot;Factory caught RECYCLING used coronavirus face masks to sell again in  Thailand&quot;,&quot;title&quot;:null,&quot;type&quot;:null,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:null,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="Factory caught RECYCLING used coronavirus face masks to sell again in  Thailand" title="Factory caught RECYCLING used coronavirus face masks to sell again in  Thailand" srcset="/__u/substackcdn.com/image/fetch/$s_!_h2J!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F55c1573f-dacd-48c4-997c-9daba3d2ba15_1280x720.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!_h2J!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F55c1573f-dacd-48c4-997c-9daba3d2ba15_1280x720.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!_h2J!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F55c1573f-dacd-48c4-997c-9daba3d2ba15_1280x720.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!_h2J!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F55c1573f-dacd-48c4-997c-9daba3d2ba15_1280x720.jpeg 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption"><em>Recycled masks. </em>RECYCLED. <a href="https://uk.news.yahoo.com/factory-caught-recycling-used-coronavirus-150000595.html">Source</a></figcaption></figure></div><p>Nevertheless, as you may have figured out by now, good faith is a sucker&#8217;s game when it comes to opposing these things. As Bezmenov said, it doesn&#8217;t matter how much evidence you bring to a communist; they&#8217;re never going to believe, understand or accept it, until that boot lands squarely on their face. Likewise, trying to argue in good faith with one&#8217;s HR department, or your local college commies, is a losing proposition.</p><p>These mandates are not grounded in reality; they are grounded in disparities of force, and driven by ideology. So too, then, is the most effective means of opposition; you have more force at your disposal than you might think, and you would be amazed at how far integrity, and standing for your principles and beliefs, can take you. Lots of people have been winning lawsuits and compensation for constructive dismissal, wrongful termination, discrimination, etc, over the mandates. A few have sadly been lost, too. Companies and corporations tend to be allergic to risk; while standing up for yourself usually does entail some degree of risk, if you can flip the tables and turn it into <em>their</em> risk, you just might come through it okay. In the end, you&#8217;re the only one that can make that determination, and you should do what&#8217;s right for you.</p><p><em>(Just for the record,</em> <em>I am not a lawyer, and this is not legal advice. Talk to a lawyer if you do end up considering legal action - there are numerous organizations that have popped up over the years that are wholly dedicated to helping us fight these fights.)</em></p><p></p><p>The resistance we offer over the next few months, particularly with regard to these mask mandates, will likely determine just how hard and far they&#8217;re going to push in the near future.</p><p></p><p>An ounce of prevention is worth a pound of cure.</p>]]></content:encoded></item><item><title><![CDATA[Threads]]></title><description><![CDATA[The demonic tapestry is beginning to unravel.]]></description><link>https://veryvirology.substack.com/p/threads</link><guid isPermaLink="false">https://veryvirology.substack.com/p/threads</guid><dc:creator><![CDATA[Adam Gaertner]]></dc:creator><pubDate>Thu, 20 Jul 2023 02:35:46 GMT</pubDate><enclosure url="https://substackcdn.com/image/fetch/$s_!qUWs!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fddd2d325-98c8-4fef-b883-e34b5b9fe140_1280x600.jpeg" length="0" type="image/jpeg"/><content:encoded><![CDATA[<div class="pullquote"><p>"If only it were all so simple! If only there were evil people somewhere insidiously committing evil deeds, and it were necessary only to separate them from the rest of us and destroy them.</p><p><em><strong>Aleksandr Solzhenitsyn</strong></em></p></div><p>Stolen elections. War for fun and profit. Gaslighting and propaganda that would make George Orwell blush. Schools more concerned with sexualizing our children than teaching them to read or count. AI so advanced that humans are fast becoming obsolete. An FBI and DOJ so thoroughly, pervasively compromised, that the special prosecutor assigned to investigate them openly admitted, to Congress, that they are now little more than the enforcement arm of the Democratic Party. A President that can&#8217;t keep his eyes open long enough to finish a sentence. Jewish organizations defending and excusing avowed Nazis. A world so exhausted by our shenanigans that they&#8217;re increasingly turning to Russia and China for freedom from the global economic order that brought us into the modern era, as it slowly collapses around us.</p><p></p><p>It&#8217;s enough to make a man drown his sorrows in despair.</p><p></p><p>And yet, for all the doom and gloom of the modern world in which we find ourselves, the light at the end of this tunnel is growing brighter. We have something that Aleksandr Solzhenitsyn pined for, something which the dissident Russians, living under Communist totalitarianism, could only have dreamed: we have clarity. We <em>know</em> who is doing this to us. We know <em>how</em> they are doing it. We even know <em>why</em> they are doing it - and, of course, despite all that, they are still doing it.</p><p>In April of this year, I wrote an article, in which I explored some of the background to what has been happening, some of those methods, the people, and their reasons; I also laid out a means by which anybody could pick up the proverbial torch and join this expansive, all encompassing, 5th-generation battlefield. There should be no doubt that we are squarely in the middle of the Third World War, and unlike practically every war that came before, there is absolutely no distinction between civilian, combatant, soldier or innocent. Every corner of every society is being touched in some way or another, and everybody has something they can contribute, big or small.</p><p>It is also very easy to lose sight, or to lose hope; with the endless new depths being plumbed every day, one might be tempted to give in. To figure that the corruption runs too deep; the election fraud, too well entrenched; or perhaps that the competing global powers, salivating at the thought of our demise, and working hand-in-glove with our most elite traitors to bring it about, are too far along, and our leaders and public servants too incompetent and corrupt to do anything but helplessly watch. Perhaps, apparently in the case of this guy, it might even be a tempting thought to jump ship and back a winning horse.</p><p>Nothing could be further from the truth. We are winning this war. Perhaps not yet on the global front, but certainly, at present, at home. It is an interesting dynamic: the World Economic Forum, having assimilated our wealthiest and most powerful individuals and organizations, now acts, by default, as our unelected, not-quite-global aristocratic rulers. In doing so, also by default, they now control and direct our foreign policy; our military, diplomatic, economic and social exports and actions; and as such, they have found themselves, of course, on a collision course with the rest of the planet, particularly Russia and China, that do not live under their thumb.</p><p></p><h2>The Enemy Of My Enemy</h2><p>In a way, it almost appears reasonable to think that the enemy of my enemy is my friend. During the Civil War, the Confederacy, in (another) act of treason, accepted French military and economic support with which to prosecute their war; given the dynamics that have been evolving on this front, would it also, then, not make sense to accept such foreign assistance against these tyrannical demons, that have undemocratically seized power and continue to push us, as hard and fast as their little feet can go, towards some nightmarish, new amalgam of the very worst aspects of Stalinism, fascism, and bad &#8216;80s cyberpunk movies, all wrapped up in love, tolerance, soft pastels and rainbows?</p><p>The answer is, of course, abso<em>lutely</em> not. To touch on the most obvious problem with that theory: <em>nobody</em> is planning, or has the means to execute, a revolutionary civil war anymore. This is not 1877, and we do not exist in a vacuum. To even contemplate such actions is to presume that, in essence, our cherished Constitution will not survive to the end of this war; were there to be any other outcome, one would end up marked a traitor from now til the end of time, and of the two sides to this civil war, the ones that want to abolish the Constitution are <em>not</em> the ones with whom we have a future. Not even a <em>good</em> future; I would wager, between the clownish incompetence both domestically and internationally, the determined kitchen-sink attempts at genocide and population control, and the ascendancy of the Eastern world and their brooding desire to avenge the various indignities visited upon them over the past century, that if these corrupt, woke, communist assholes were to win out, we will have no future, period. Our countries - both here in the US and across Europe - will cease to exist, splintered by politics, economies, ideologies, religions, and ethnic and immigration divides, and a hundred years from now, it will be Russia, China and Africa calling us the third world, charitably providing food aid and testing the occasional biological weapon or two.</p><p>No: no matter what ends up happening here, any such help would come as the ultimate poisoned chalice, and were it to actually succeed in making any material difference to the situation, it would undoubtedly have come at the price of demolishing the very thing that one had set out to preserve.</p><p>Nevertheless, we do, in fact, find ourselves in something approximating that situation anyway. Mostly by way of the incredible incompetence of the WEF-istas, and their handpicked puppets - having been chosen for ideology over merit, burrowed throughout the bureaucracies and positions of power over decades, and now wreaking clown-world lunacy everywhere they go - and the fact that they have, forcibly and without our consent, tied all of our fortunes to theirs - the Great Powers of the world have joined the fight against them, and <em>how</em> are they kicking their asses on pretty much every front. It&#8217;s just quite unfortunate that our asses are getting kicked right alongside theirs. Russia, China, and BRICS - which is ever-expanding, to include even prospectively <em>Mexico</em>, not to mention the recent addition of Saudi Arabia, on whom the dollar dominance rests - have been slowly but surely etching away their power base, founded chiefly on the oil, the dollar, global development and debt, and behind it all, our rapidly depleting military force.</p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://veryvirology.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">To receive new articles and support this work, please consider becoming a free or paid subscriber. It makes a difference!</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div><h3>China</h3><p>With the competence of meritocracy - and in China&#8217;s case, generations of totalitarian eugenics, geared to produce the most diligent and intelligent, and to hell with the rest - and the foresight and planning of dictatorships that do not need to contend with radical shifts in policy every four years, our enemies have us, as a nation and a hegemonic empire, falling into traps and plans they have long laid out. A world under Chinese rule will be everything we fear at home from the WEF, but writ large, and firmly out of our control. Whatever one might think of the Pax Americana - our proclivity to go to war for one reason or another, or the economic exploitation we have perpetuated against African and South American nations, or the stranglehold we keep on nations far and wide with our dollar and our military - well, as they say, democracy is the worst form of governance, except for all the others.</p><p>China&#8217;s initial moves have been to bring peace. Peace between the Saudis, the Iranians, the Yemenis, and the Syrians; now, if you&#8217;ve been paying attention, that bloc, primarily Sino-centric now, is already coming into conflict with the Russian sphere of the Middle East, with Turkey, ostensibly our ally, caught in the middle and surrounded on all four sides. A Chinese world may well be a peaceful one; when it is enforced at the barrel of a gun, by a facial recognition drone being operated 1000 miles away, it brings new meaning to &#8220;peace through superior firepower.&#8221; Peaceful as it may be, if the trajectory of Chinese social credit and CBDC systems is any indication, it will be a peace obtained by the loss of our collective humanity and adsorption into a world-spanning Chinese hive. The WEF wants something similar; to hear them tell it, by 2030 the only fashion we&#8217;ll ever need will be the uniforms we wear in our 15 minute cities - but these absolute morons, having seized their little bit of power, have found themselves playing a geopolitical board for which they were <em>laughably</em> unprepared, and their days are now numbered; they have absolutely no chance of accomplishing any of those goals before they, and the rest of us with them, end up roadkill on the highway, as China seizes power from the vacuum they created.</p><p></p><h3>Russia</h3><p>One of the worst lies of the war in Ukraine, and one of the justifications for the war beyond the farcical defense of dictatorial, Nazi-led &#8220;democracy&#8221;, is that if Ukraine falls, Poland and Lithuania will be next to fall to an newly expansionist Russia, which is why we have to deplete everything we&#8217;ve got to fight them, to the last Ukrainian, on Ukrainian territory. The kinetic war against Russia started in 2008, in South Ossetia, Georgia, on Russia&#8217;s southern border, just to the north of which is the rebellious Chechen Muslim regions of Russia. The US had been conducting training and joint operations in Georgia, in pursuit of ostensibly admitting Georgia to NATO.</p><p>One fine morning, then-President of Georgia, Mikhail Saakashvili, began shelling, apropos of absolutely nothing, civilian structures and buildings in the city of Tskhinvali. The Russian peacekeepers in the area, sparse in number and armament, were bypassed, to begin the utterly senseless attacks on what were predominately ethnic Russian Georgians living in the region. Attacks on Abkhazia, a similar small region, also began shortly thereafter. The Russian military, caught by surprise, rushed to send a massive combined-arms assault on the Georgian forces; at the time, there was much gnashing of teeth about a particular mountainous tunnel through which the Russian forces must have passed before they would be able to fight Georgia, and an effort to collapse it. That effort failed: the Russians broke through, and subsequently, the Georgian military, and even the local police forces in the northern cities, were completely and utterly routed, abandoning their uniforms and vehicles and streaming towards the perceived safety of the Georgian capital Tbilisi. One of the funniest moments of the &#8220;war&#8221; was a haggard Saakashvili, looking decidedly unpresidential in military fatigues and a bulletproof vest, giving a panicked press conference in the middle of Tbilisi, vowing to defend his country to the end and whining about the Russian &#8220;invasion.&#8221;</p><p>The Russians did not, in fact, end up pursuing those forces all the way to Tbilisi, or making any expansionist effort to take control of the country. Even though the Russian forces were also hilariously incompetent - they managed to lose a few fighter jets to human error, despite a total lack of Georgian anti-air defense - their only goal, which was achieved, was to defend settlements of ethnic Russians against what was, as the EU eventually acknowledged, a completely senseless military assault on defenseless Russian civilians, without any provocation whatsoever. With the Georgian forces in total rout and disarray, and our &#8220;advisors&#8221; having fled at the first sign of the Russian invasion, taking control of the country would have been incredibly easy.</p><p>Why did Georgia do that? Because we told them to do that.</p><p>What is it that the Russians keep saying Ukraine has been doing since 2014? Something about senselessly shelling ethically Russian civilians in the eastern part of the country for the better part of the last decade? I believe there was also a very detailed article about how the CIA has been present in eastern Ukraine, training the Nazi Azov forces, and &#8220;assisting&#8221; with &#8220;fighting&#8221; the &#8220;Russians&#8221; over there?</p><p>The plain truth of the matter is, that for whatever reason our deep state may have, we have been using our proxies to attack Russia and Russian civilians for the better part of 20 years now. Russia&#8217;s response has been to carve out limited, small demilitarized zones in the offending countries, sufficient in their minds to keep us and our proxies far enough away that we can&#8217;t just wake up one day and decide to bomb their civilians again. Their actions, despite certainly constituting invasions and seizures of the territories of otherwise sovereign nations, appear to have been entirely and maximally minimally defensive.</p><p>The last thing Russia is trying to do is reclaim their Soviet empire, much less start or at least risk a nuclear war with NATO to seize a couple of poor, under-developed countries on the eastern flank. We won the cold war. It&#8217;d be really great if our leaders would recognize that. Unfortunately they seem to have made plans otherwise - and now they&#8217;re backfiring, badly.</p><p>Ending the war in Ukraine is incredibly simple. Remove Zelensky and his merry band of Nazis, stop shooting at the Russians, and maybe in a decade or two they&#8217;ll even give back some of those eastern territories. Medvedev said at one point - the longer-range weapons we give them, the more of Ukraine they&#8217;ll have to seize for their buffer zones.</p><p>I&#8217;d wager that President Trump&#8217;s plan is something along those lines. Those actions could certainly end the war &#8220;tomorrow.&#8221;</p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://veryvirology.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">To receive new articles and support this work, please consider becoming a free or paid subscriber. It makes a difference!</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div><p>In an interesting note, Saakashvili served out the remainder of his Presidential term, and in 2014, after the Euromaidan coup in Ukraine, moved to Ukraine and lived there under the new regime. In late 2021, he returned to Georgia, where he was promptly arrested for plotting a coup. Seems like somebody was thinking about also reopening that Georgian front - the protests and near-overthrow of their government late in 2022 might also have been pursuant to that. Unfortunately for them, it doesn&#8217;t seem to have worked out very well. Ukraine, just after attacking the Kerch bridge and sinking the Grain Deal, just asked for Saakashvili to be returned to Ukraine.</p><p>Needless to say, they weren&#8217;t exactly receptive.</p><p></p><h3>The WEF</h3><p>So, needless to say at this point - the Russians and the Chinese have very much got their hands full with their own plans. It seems a lot like the WEF only planned as far as actually taking power over the Western world; now that they&#8217;ve got it, what are they going to do with it? Launch a kinetic war against Russia, for which we were woefully unprepared, within two years of having completely seized the Presidency? They did have the Presidency under Obama, but only to a degree; he was certainly on their team, and <em>man</em> did he do a lot of damage for them, but he wasn&#8217;t simply a rubber stamp - say what you like about him, but he was certainly a competent and intelligent man, and working within the still-competent confines of the US government apparatus, we didn&#8217;t have to suffer the indignity of our entire global empire slowly imploding, one domino after another. We certainly did suffer under Obama, but for malice, not incompetence and total absence of leadership; the difference is now, I hope, clear.</p><p>The Achilles heel of the Klaus Schwabs and the Bill Gates of the world is their boundless arrogance; a close second is their penchant for symbolism and ritual, particularly the revelation of the method. You can <em>always</em> count on some clear indication of whatever their next depraved move is going to be; once upon a time, such conspiracies were actually kept secret, but these days it seems like they prefer to wrap them in rainbows and Orwellian language instead. These are fatal weaknesses, and from the perspectives of our enemies, with the bureaucracies and policies of our nations now dancing to these tunes, we must look like absolute amateur hour clowns.</p><p>If these people remain in power, we will be destroyed, and our enemies will be laughing as they do it; while the WEF-istas will certainly fall from grace in such a scenario, it will hardly be a victory for the rest of us as we are plunged into poverty, famine, international isolation, and probably some manner of civil conflict. Europe particularly, having absorbed untold numbers of hostile African refugees for at least a generation now, is in for a particularly difficult time. We cannot simply sit back and have Russia, China or BRICS fight our battles for us; they&#8217;re <em>our</em> elites, as sour a taste as that might leave in one&#8217;s mouth, and as such, they are <em>our</em> problem.</p><h3></h3><h3>Nevertheless&#8230;</h3><p>You may or may not be aware of this, but Russia and China are not natural allies; nor is the rest of this shaky coalition that has been gradually developing around BRICS. Their alliance and cooperation is one of convenience and necessity; they have been pretty much forced into it, as a matter of survival, in the face of our military aggression and weaponization of our vast economic and structural might. A world in which the Pax Americana reigns supreme is still the best of all worlds, for all concerned; while China does have their imperial ambitions, their incipient realization of them is more a matter of opportunism, on the top of our dismally failing foreign policies, than any particularly concerted effort to bring it all to fruition right now.</p><p>In other words - all is not lost on the geopolitical stage, either. Should we somehow manage to wrest control of our own country back again, and see to it that patriotic, competent people are back in power and running it, all the damage of recent years is reversible; with a leader like Trump or RFK, even our enemies would likely welcome it (and perhaps, just maybe, cease holding such enmity), and if that stability could be guaranteed moving forwards, we could well hit that infamous &#8216;reset&#8217; button and carry on like nothing ever happened - presuming that Russia isn&#8217;t feeling vengeful for their and Ukraine&#8217;s hundreds of thousands of dead, anyhow. That&#8217;s a tougher one.</p><p>Nevertheless, we have our work cut out for us: we have to finish the job of rooting out and destroying this cancer that has infiltrated us. The first - and sometimes, only - step to facilitate that, is simply being able to recognize it. The reason they fight the definition of &#8220;woke&#8221; so hard is that once it is defined, it becomes recognizable, and it becomes fightable. You may have noticed how &#8220;woke&#8221; has become something of a catchall term for insane far leftists and the corrupt, or ideologically indoctrinated, officials that enable them; that we have now, as a society, managed to firmly define them, is a deadly risk to them, one made possible by both their general arrogance, and their fatally flawed methodologies.</p><p>Russia and China are not stupid; they know their enemy, they know how woefully inadequate these WEF types and their lackeys are to wield the risks and responsibilities of nation-states, and they are, in gross aggregate, being severely degraded and defeated in detail. This weakness becomes visible, like leaks in a rotted old dinghy, in random and unexpected places; these odd appearances, more than the specific subject matter of any one event, are indicative of deep vulnerability, the kind of vulnerability that allows us to continue chipping away at their house of cards - and maybe, just maybe, with the escalating desperation and continual mistakes being made on the home front, the thread that will unravel it all will come loose.</p><div class="captioned-image-container"><figure><a class="image-link image2" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!qUWs!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fddd2d325-98c8-4fef-b883-e34b5b9fe140_1280x600.jpeg" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!qUWs!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fddd2d325-98c8-4fef-b883-e34b5b9fe140_1280x600.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!qUWs!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fddd2d325-98c8-4fef-b883-e34b5b9fe140_1280x600.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!qUWs!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fddd2d325-98c8-4fef-b883-e34b5b9fe140_1280x600.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!qUWs!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fddd2d325-98c8-4fef-b883-e34b5b9fe140_1280x600.jpeg 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!qUWs!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fddd2d325-98c8-4fef-b883-e34b5b9fe140_1280x600.jpeg" width="377" height="176.71875" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/ddd2d325-98c8-4fef-b883-e34b5b9fe140_1280x600.jpeg&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:600,&quot;width&quot;:1280,&quot;resizeWidth&quot;:377,&quot;bytes&quot;:null,&quot;alt&quot;:&quot;How to Fix a Snagged Thread in Your Favorite Sweater &#171; Fashion ::  WonderHowTo&quot;,&quot;title&quot;:null,&quot;type&quot;:null,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:null,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="How to Fix a Snagged Thread in Your Favorite Sweater &#171; Fashion ::  WonderHowTo" title="How to Fix a Snagged Thread in Your Favorite Sweater &#171; Fashion ::  WonderHowTo" srcset="/__u/substackcdn.com/image/fetch/$s_!qUWs!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fddd2d325-98c8-4fef-b883-e34b5b9fe140_1280x600.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!qUWs!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fddd2d325-98c8-4fef-b883-e34b5b9fe140_1280x600.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!qUWs!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fddd2d325-98c8-4fef-b883-e34b5b9fe140_1280x600.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!qUWs!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fddd2d325-98c8-4fef-b883-e34b5b9fe140_1280x600.jpeg 1456w" sizes="100vw" loading="lazy"></picture><div></div></div></a><figcaption class="image-caption"><em>Don&#8217;t stop pulling.</em></figcaption></figure></div>]]></content:encoded></item><item><title><![CDATA[Prions: One Of These Things Is Not Like The Others]]></title><description><![CDATA[A surprising development constitutes some unexpectedly good news.]]></description><link>https://veryvirology.substack.com/p/prions-one-of-these-things-is-not</link><guid isPermaLink="false">https://veryvirology.substack.com/p/prions-one-of-these-things-is-not</guid><dc:creator><![CDATA[Adam Gaertner]]></dc:creator><pubDate>Tue, 20 Jun 2023 06:05:31 GMT</pubDate><enclosure url="https://substack-post-media.s3.amazonaws.com/public/images/3709c5be-2f86-4bc4-9308-05b66e9309a2_1200x630.png" length="0" type="image/jpeg"/><content:encoded><![CDATA[<p>Among the many terrible gain-of-function insertions to call SARS-CoV-2 home, the worst has long been - by some, anyhow - thought to be the inclusion of prionic domains in the spike protein, which would, hypothetically, set every one of us who suffered an infection, or received an mRNA hot shot, on a potentially decades-long, irreversible, and incurable path towards eventually fatal neurodegeneration and death. I have personally been concerned about it, and had been working on it, since March 18th, 2021, and made some good, albeit limited progress over time, with an unfortunate false start and a lot of difficulty along the way. While I wasn&#8217;t the first - I believe Dr. Kevin McCairn (not to be confused with Dr. McKernan, who recently sequenced SV40 DNA in the mRNA shots) rightly deserves that distinction, for his very early work on this - I was still pretty early, and it&#8217;s been a point of interest and investigation for me for quite some time. It has since been confirmed by NIH-affiliated scientists, and while there&#8217;s no planet on which ubiquitous exposure to a prion protein could be considered good news, there is in fact a saving grace which, in my opinion, makes this particular prion disease far less dangerous than initially thought.</p><p>Let&#8217;s dig into that.</p><p></p><h2>Protein Folding</h2><p>Every cell in our bodies, and a great number of the smaller components which are found both inside and outside of those cells, is made of proteins in various capacities. They are chains of amino acid molecules, organized and bound together in helices, sheets, turns, and coils, by the ribosomes which read the mRNA produced from our DNA. Not dissimilarly to a 3D printer, the ribosome uses the mRNA to determine the order in which amino acids are to be attached to the strand of protein being output; consider it a printer head, which is constantly changing material within the same stream of material. Every bond between the different amino acids exhibits different physical properties; these properties inform the strength, direction and orientation of their binding to the neighboring amino acids. Imagine a 3D printer outputting a stream of hot plastic; if not properly calibrated, that plastic will bend, loop, curve, and (only occasionally!) produce the straight line that you actually wanted from it.</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!JzGI!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F74bc4ac6-ca45-46dc-b58f-173a505ead76_600x700.gif" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!JzGI!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F74bc4ac6-ca45-46dc-b58f-173a505ead76_600x700.gif 424w, /__u/substackcdn.com/image/fetch/$s_!JzGI!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F74bc4ac6-ca45-46dc-b58f-173a505ead76_600x700.gif 848w, /__u/substackcdn.com/image/fetch/$s_!JzGI!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F74bc4ac6-ca45-46dc-b58f-173a505ead76_600x700.gif 1272w, /__u/substackcdn.com/image/fetch/$s_!JzGI!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F74bc4ac6-ca45-46dc-b58f-173a505ead76_600x700.gif 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!JzGI!,w_1456,c_limit,f_auto,q_auto:good,fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F74bc4ac6-ca45-46dc-b58f-173a505ead76_600x700.gif" width="472" height="550.6666666666666" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/74bc4ac6-ca45-46dc-b58f-173a505ead76_600x700.gif&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:700,&quot;width&quot;:600,&quot;resizeWidth&quot;:472,&quot;bytes&quot;:13571522,&quot;alt&quot;:null,&quot;title&quot;:null,&quot;type&quot;:&quot;image/gif&quot;,&quot;href&quot;:null,&quot;belowTheFold&quot;:false,&quot;topImage&quot;:true,&quot;internalRedirect&quot;:null,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="" srcset="/__u/substackcdn.com/image/fetch/$s_!JzGI!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F74bc4ac6-ca45-46dc-b58f-173a505ead76_600x700.gif 424w, /__u/substackcdn.com/image/fetch/$s_!JzGI!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F74bc4ac6-ca45-46dc-b58f-173a505ead76_600x700.gif 848w, /__u/substackcdn.com/image/fetch/$s_!JzGI!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F74bc4ac6-ca45-46dc-b58f-173a505ead76_600x700.gif 1272w, /__u/substackcdn.com/image/fetch/$s_!JzGI!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F74bc4ac6-ca45-46dc-b58f-173a505ead76_600x700.gif 1456w" sizes="100vw" fetchpriority="high"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption">Well, that wasn&#8217;t supposed to happen. Does look a lot like a protein, though! <a href="https://realvisiononline.com/blog/the-12-most-common-problems-in-3d-printing-and-how-to-fix-them">Source</a></figcaption></figure></div><p>Proteins are formed in the same way: upon being output, they <em>fold</em> into a practically limitless array of different conformations. This process is so complex, operating purely based on the various laws of physics which dictate the attraction and repulsion of atoms and molecules, that even in our modern era, it still takes massive computing resources to brute-force search through every possible permutation until the correct one is identified. This process, and also, separately, the computational work that goes into predicting it, is known as protein folding. Despite the infinite complexity of this process, our DNA has evolved, by trial and error, to (<em>almost</em>) always produce proteins in such a way as to create perfectly formed proteins.</p><p>Imagine trying to build a clockwork wristwatch, comprised of so many perfectly calibrated cogs, bars, springs and screws, one part at a time, with only the meandering, ostensibly random coils of a partially clogged 3D printer head to do it. That&#8217;s what our ribosomes are doing, all day every day.</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!b_oU!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F9c5341b5-8ead-46d3-b73d-e904049dd9af_480x270.gif" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!b_oU!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F9c5341b5-8ead-46d3-b73d-e904049dd9af_480x270.gif 424w, /__u/substackcdn.com/image/fetch/$s_!b_oU!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F9c5341b5-8ead-46d3-b73d-e904049dd9af_480x270.gif 848w, /__u/substackcdn.com/image/fetch/$s_!b_oU!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F9c5341b5-8ead-46d3-b73d-e904049dd9af_480x270.gif 1272w, /__u/substackcdn.com/image/fetch/$s_!b_oU!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F9c5341b5-8ead-46d3-b73d-e904049dd9af_480x270.gif 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!b_oU!,w_1456,c_limit,f_auto,q_auto:good,fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F9c5341b5-8ead-46d3-b73d-e904049dd9af_480x270.gif" width="480" height="270" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/9c5341b5-8ead-46d3-b73d-e904049dd9af_480x270.gif&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:270,&quot;width&quot;:480,&quot;resizeWidth&quot;:null,&quot;bytes&quot;:null,&quot;alt&quot;:&quot;Ribosomes GIFs - Get the best GIF on GIPHY&quot;,&quot;title&quot;:null,&quot;type&quot;:null,&quot;href&quot;:null,&quot;belowTheFold&quot;:false,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:null,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="Ribosomes GIFs - Get the best GIF on GIPHY" title="Ribosomes GIFs - Get the best GIF on GIPHY" srcset="/__u/substackcdn.com/image/fetch/$s_!b_oU!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F9c5341b5-8ead-46d3-b73d-e904049dd9af_480x270.gif 424w, /__u/substackcdn.com/image/fetch/$s_!b_oU!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F9c5341b5-8ead-46d3-b73d-e904049dd9af_480x270.gif 848w, /__u/substackcdn.com/image/fetch/$s_!b_oU!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F9c5341b5-8ead-46d3-b73d-e904049dd9af_480x270.gif 1272w, /__u/substackcdn.com/image/fetch/$s_!b_oU!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_lossy/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F9c5341b5-8ead-46d3-b73d-e904049dd9af_480x270.gif 1456w" sizes="100vw"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption">Artist&#8217;s impression of ribosomal protein folding. <a href="https://news.ucsc.edu/2008/04/2083.html">Direct observations</a> have also been made.</figcaption></figure></div><h2>When It Goes Wrong</h2><p>Of course, this process is, whilst <em>nearly</em> perfect, not entirely perfect. With such a complex system, occasional errors are to be expected. For this reason, we have a number of other proteins - that hopefully were formed correctly! - that stand guard and act as the quality control. Some, like the chaperones, which I covered in the <a href="/__u/veryvirology.substack.com/p/curing-the-incurable-cancer">article on cancer</a>, will take a misfolded protein and attempt to re-fold it into its proper conformation. Others will simply destroy and recycle the base amino acid components of a misfolded protein. However, they are both imperfect and a double edged sword. Overactivity can result in the preservation of an extensively mutated cell&#8217;s proteins and permit a cancer cell to survive; and the evolution of protease-resistant misfolded proteins are a causative factor of numerous neurodegenerative diseases. They can&#8217;t, and don&#8217;t, do everything; some proteins can neither be reformed nor destroyed. Those proteins, rather than going off to live their lives as the cogs in the machine they were supposed to be, end up accumulating in piles of garbage, better known as plaques, both interfering with the proper functioning of various bodily systems and, by virtue of their absence, degrading the functionality of whichever system they were supposed to be part of. This is a major factor in Alzheimer&#8217;s disease, which I touched on in the very first article I ever published to Substack, among others.</p><p>However, these are still not prions.</p><p></p><h2>When It Goes Really Wrong</h2><p>A misfolded protein is bad enough; a misfolded protein will fail to perform its duty, and some will aggregate together to form a garbage heap, whether inside or outside of a cell, interfering in the ordinary operation of the microbiological machinery that keeps us ticking. However, it gets worse. Here, we come to prions.</p><p>A prion is a misfolded protein, just like the others. However, it is a misfolded protein which <em>also causes other, properly folded proteins</em> to become misfolded<em>.</em> Think of a prion protein like the pink-haired, trans-ally, elementary school math teacher; not only is it failing to teach the kids their math lesson, it&#8217;s dimming the lights and making the kids watch a video on how you too can become a eunuch, and expounding at length on how beautiful and normal that is. Not every protein is vulnerable. The teacher in this scenario is the prion <em>seed</em>. When a vulnerable, properly folded protein comes into contact with the prionic protein, the seed protein causes conformational changes to it, converting it into a similarly infectious shape. The best example of this is the eponymously named prion protein. In the proper, natural conformation, PrPC, it is an important cog in the brain&#8217;s machinery, thought to aid in cell signaling, protecting neurons, and facilitating synaptic plasticity. However, upon exposure to the misfolded form, PrPSC, the healthy PrPC changes its conformation, and becomes the prionic PrPSC form; having lost its original shape, it is no longer capable of performing its natural function, and instead begins adhering to a cell membrane, forming a disruptive plaque. Any healthy PrPC protein that is unfortunate enough to come into contact with the PrPSC protein will be converted into PrPSC. Eventually, the plaque reaches a critical mass, and instead of further aggregating into the plaque, they begin to instead form long fibrils, growing out from the plaque and dramatically increasing the surface area by which healthy proteins may be &#8220;infected.&#8221; At this stage, the plaques begin growing everywhere, significantly damaging and destroying brain tissue, and causing the symptomatic phase of such diseases as Creutzfeld-Jakob Disease, also known as CJD or mad cow disease, Kuru, and other similar ailments.</p><div class="native-video-embed" data-component-name="VideoPlaceholder" data-attrs="{&quot;mediaUploadId&quot;:&quot;1ae13da1-c2d6-4338-a97a-bb467127a708&quot;,&quot;duration&quot;:null}"></div><p>This process, at every stage, but especially the final fibrillization phase, is universally accepted to be incurable, and inevitably fatal, and usually in relatively short order upon presentation of symptoms. With the observation that the spike protein was exhibiting prion-like behavior, made so long ago and with extremely limited, but nonetheless convincing evidence, this was reasonably presumed to be the likely process that would be followed, and the inevitable outcome.</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!H_XH!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fe160ca28-88e4-41b5-9434-dd789eb16f92_850x529.png" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!H_XH!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fe160ca28-88e4-41b5-9434-dd789eb16f92_850x529.png 424w, /__u/substackcdn.com/image/fetch/$s_!H_XH!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fe160ca28-88e4-41b5-9434-dd789eb16f92_850x529.png 848w, /__u/substackcdn.com/image/fetch/$s_!H_XH!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fe160ca28-88e4-41b5-9434-dd789eb16f92_850x529.png 1272w, /__u/substackcdn.com/image/fetch/$s_!H_XH!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fe160ca28-88e4-41b5-9434-dd789eb16f92_850x529.png 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!H_XH!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fe160ca28-88e4-41b5-9434-dd789eb16f92_850x529.png" width="545" height="339.1823529411765" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/e160ca28-88e4-41b5-9434-dd789eb16f92_850x529.png&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:529,&quot;width&quot;:850,&quot;resizeWidth&quot;:545,&quot;bytes&quot;:42831,&quot;alt&quot;:null,&quot;title&quot;:null,&quot;type&quot;:&quot;image/png&quot;,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:null,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="" srcset="/__u/substackcdn.com/image/fetch/$s_!H_XH!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fe160ca28-88e4-41b5-9434-dd789eb16f92_850x529.png 424w, /__u/substackcdn.com/image/fetch/$s_!H_XH!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fe160ca28-88e4-41b5-9434-dd789eb16f92_850x529.png 848w, /__u/substackcdn.com/image/fetch/$s_!H_XH!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fe160ca28-88e4-41b5-9434-dd789eb16f92_850x529.png 1272w, /__u/substackcdn.com/image/fetch/$s_!H_XH!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fe160ca28-88e4-41b5-9434-dd789eb16f92_850x529.png 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption">Healthy vs misfolded prion protein. <a href="https://www.researchgate.net/publication/361314702_Prionvirus_the_danger_of_biological_weapons">Source</a></figcaption></figure></div><p>Now we know more, and amazingly, it&#8217;s actually much better news than I think anybody expected.</p><h2>Spike-Prion Work Over The Years</h2><p>Throughout the early work on this issue, there were many areas of uncertainty. Exactly which regions of the spike are supposed to be acting in this way? Which other proteins are they actually infecting and causing to become misfolded? How long should we expect the latent phase of the disease, wherein the prionic proteins are aggregating but not yet causing symptoms, to last, as opposed to the active, symptomatic and fatal phase? In my <a href="/__u/veryvirology.substack.com/p/archival-this-is-how-they-tell-me">article</a>, dated July of 2021, I proposed that the PrP may be affected, and speculated that a zombie apocalypse may eventuate. There are a number of other proteins known to exhibit amyloidogenic activity; tau, TDP-43, &#945;-synuclein and PrP among them, all of which aggregate for different reasons, in different locations, and cause different issues.</p><p>I also took the step of soliciting and aggregating data on people who had developed symptoms of, obtained a diagnosis of, and/or died of Creutzfeld-Jakob-like symptoms, at various time intervals after their receipt of the spike-encoding mRNA vaccines, alongside early research work into potentially useful therapeutics. The results were very concerning, and helped to initiate broader research efforts by various individuals across the world. In sum, I collected data on approximately 60 cases. All of them demonstrated symptomatic onset between 7 to 30 days after the mRNA shots. There were questions about the brand of vaccine; they were heavily weighted towards Pfizer. There were also questions about whether it was simply background noise; while it is extremely rare, occurring in about 1 in a million people, there are many millions of people in the world, and while that dataset did not, very strictly speaking, exceed the background rate, it was definitely significant enough, alongside the temporal correlation to mRNA administration, to warrant a closer look.</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!6bjS!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F61efc9cc-4404-43ca-a0b7-3f67eaf7af15_850x456.jpeg" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!6bjS!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F61efc9cc-4404-43ca-a0b7-3f67eaf7af15_850x456.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!6bjS!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F61efc9cc-4404-43ca-a0b7-3f67eaf7af15_850x456.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!6bjS!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F61efc9cc-4404-43ca-a0b7-3f67eaf7af15_850x456.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!6bjS!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F61efc9cc-4404-43ca-a0b7-3f67eaf7af15_850x456.jpeg 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!6bjS!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F61efc9cc-4404-43ca-a0b7-3f67eaf7af15_850x456.jpeg" width="565" height="303.1058823529412" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/61efc9cc-4404-43ca-a0b7-3f67eaf7af15_850x456.jpeg&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:456,&quot;width&quot;:850,&quot;resizeWidth&quot;:565,&quot;bytes&quot;:null,&quot;alt&quot;:&quot;Image&quot;,&quot;title&quot;:null,&quot;type&quot;:null,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:null,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="Image" title="Image" srcset="/__u/substackcdn.com/image/fetch/$s_!6bjS!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F61efc9cc-4404-43ca-a0b7-3f67eaf7af15_850x456.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!6bjS!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F61efc9cc-4404-43ca-a0b7-3f67eaf7af15_850x456.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!6bjS!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F61efc9cc-4404-43ca-a0b7-3f67eaf7af15_850x456.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!6bjS!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F61efc9cc-4404-43ca-a0b7-3f67eaf7af15_850x456.jpeg 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption"><em>My raw data on prion disease and death contemporaneous with vaccination, collected via self-reporting, in late 2021.</em></figcaption></figure></div><p>Unfortunately, the work was, temporarily, shelved, later in 2021. Unlike many these days, I do not approach a topic with a pre-determined answer, and then set out to massage the data to elicit a proof. Considering the heavy slant of the data towards the Pfizer shots, we found another, very plausible explanation: a footnote, at the bottom of an EU document relating to its approval, stated that due to their use of processed animal fats, primarily cows, to produce the lipid nanoparticles within which the mRNA is encased for administration, they acknowledged the possibility of prion protein contamination stemming from the processing of those animal tissues. It was also not yet established that approximately <a href="https://twitter.com/SaiKate108/status/1667500388017401856">only 5% of the administered mRNA shots are actually active</a>, with the remainder being partially or completely inactivated due to either storage concerns, or something perhaps more nefarious, and thus not actually capable of causing spike mRNA production.</p><p>In summary, the EU acknowledgement that a number of Pfizer batches may exhibit prion protein contamination, considered alongside the facts that the small number of cases linked to other brands certainly did not exceed the background rate, the yet-unknown even further diminishing of the disease rate due to the &#8220;hot shot&#8221; batch differentials, and the complete absence of any such reports connectable only to infection by the SARS-CoV-2 virus, it appeared that sufficiently strong evidence simply wasn&#8217;t there to firmly draw a connection between the spike and the observed prion diseases; the far more likely explanation was prion protein contamination of a very few Pfizer batches, and purely coincidental cases of people who happened to receive a vaccine of a different brand, the rate of which was well within the expected background rate.</p><p>Accordingly, I announced my findings, and, at least for a time, that was that; while this conclusion was tentatively agreed to be plausible by others who were also looking into it, not everybody was convinced, and fortunately, some theoretical research work went on.</p><p>Fast-forwarding 12 months to the beginning of this year, and those initial findings - specifically, the <a href="https://www.researchgate.net/publication/363484655_Towards_the_emergence_of_a_new_form_of_the_neurodegenerative_Creutzfeldt-Jakob_disease_Twenty_six_cases_of_CJD_declared_a_few_days_after_a_COVID-19_vaccine_Jab">emergence of a new form of Creutzfeld-Jakob disease</a>, noted to be affecting people shortly after having received mRNA vaccinations - have now been observed elsewhere, confirmed, and written up in a published study by Dr. Jean-Claude Perez et al. While unsettling, the samples are still just too small to firmly draw a conclusion, especially a wide-ranging one, such that every person who received a vaccine, or every person infected by SARS-CoV-2, should be looking forwards to an unfortunate, if long delayed, eventual expiration via prion-induced neurodegeneration. It certainly seemed that way to me; if the spike itself is the prion protein of concern, how could it not?</p><p>I will make note at this point that Omicron was a very strange emergence. First characterized in South Africa, it derived directly from the Alpha lineage. Before Omicron, there was Delta, and a long line of variants before it; the emergence of that virus, at that time, is something akin to an ancient zombie virus being discovered in the Siberian permafrosts. It just shouldn&#8217;t happen. Nevertheless, it did happen, and it came with a number of notable elements: particularly of relevance here is the absence of the inserted HIV residues (specifically, <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8723827/">G142D/&#916;143-145</a>, within the <a href="https://www.biorxiv.org/content/10.1101/2020.01.30.927871v1.full">136-150 gp120 domain</a>) which were among those on the spike expected to exhibit prionic activity. It sure seems like somebody took SARS-CoV-2, removed the very worst gain-of-function elements, improved the transmissibility whilst decreasing the virulence, and set it loose on the world to replace the escalatingly dangerous Delta variant.</p><p>If that is in fact what happened - of course there is no particular evidence of that, beyond a circumstantial look at the bigger picture, and how such a release might have factored into the geopolitical machinations taking place in the broad context of this pandemic - then we probably owe the responsible party some thanks. It is due to those modifications, specifically to the gp120 region, that every time somebody asks me whether it&#8217;s just the shots, or also exposure to the virus, that puts people at risk for prion disease, I will tell you that it is any of:</p><ul><li><p>People who received a hot shot (ie the 5% of the batches causing adverse events)</p></li><li><p>People infected with any variant of SARS-CoV-2 prior to Omicron.</p></li></ul><p>I count myself among the latter, having been infected early in March of 2020, and having reached a point of severe pneumonia, as well as some eye-opening neurological effects, before both discovering and then successfully using first ascorbic acid to hold it at bay, and then ivermectin to finally and fully cure it. However, the possibility of the presence of a slow-burning prion infection has been on my mind for years now.</p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://veryvirology.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">To receive new articles and support this work, please consider becoming a free or paid subscriber. It makes a difference!</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div><p>So, that&#8217;s the (relatively) short version of the various types and locations of work that have been happening on the prion disease front over time. I could discuss the lab - but all I really have to say about that at this point is that I hope failure builds character. Since funding the development &amp; readying of a non-invasive prion blood test, and the lab to provide it, as opposed to the invasive, dangerous, painful and standard spinal tap, I have had several false starts insofar as my desire to begin conducting broad, indiscriminate, population-level testing. Such testing and information would be able to tell us, once and for all, if we are in fact facing a latent, widespread prion pandemic. Alas, if it is to eventually be done, it doesn&#8217;t really seem at this point like I&#8217;m the one that is going to do it. It&#8217;s still there, gathering dust. Maybe one day it&#8217;ll be put to use.</p><p></p><h2>The Good News</h2><p>I did promise good news, didn&#8217;t I? It&#8217;s probably about time to get into that.</p><p>There is not, ordinarily, a whole lot of good news to be had concerning prion diseases. There have only been a very few, vanishingly rare cases in which a prion infection has been cured; whether by pure chance, or remission, or misdiagnosis, there have not been enough cases to say with any certainty. Let&#8217;s go back to the watch analogy; the entire watch body is made of steel, or aluminum, or whatever it is that they make watches out of these days; likewise, the components are made of the same parts. Take that watch, and start growing a little pile of metal within it; now you have a little pile of metal in the corner, not yet interfering with its operation, but ever so steadily growing. If you try to dissolve it, it&#8217;s going to destroy the rest of it; if you let it continue growing, it&#8217;s going to destroy the watch; and by the time anybody notices the gears aren&#8217;t turning properly, the cogs look more like blobs, and there&#8217;s really no salvaging it anymore. There is very little good news when it comes to prion diseases.</p><p>&#8220;But Adam,&#8221; they ask, &#8220;Surely they wouldn&#8217;t release a bioweapon without themselves having the cure, right? There must be one!&#8221; Considering how clearly premeditated this all is - and the fact that the people aiding and abetting this biowarfare have also themselves been, if not exposed to the real &#8220;vaccines,&#8221; at least infected with various strains of the virus - it&#8217;s a valid question, and one I have not, until now, been able to answer.</p><p></p><p>We still need a little more background before we get to that good news, though.</p><p></p><h2>The Prion-Like Domains</h2><p>The SARS-CoV-2 S protein has several prion-like domains. While initially it was thought that the addition of the HIV gp120 protein should have been primarily, or even solely responsible, we now have a firm identification of these domains. So, that&#8217;s great - but why is it good news?</p><p>Prionic proteins usually affect only other proteins that are just like them, although in some cases, such as Alzheimer&#8217;s disease, the downstream effects can, directly or indirectly, cause aggregation of other proteins. An outstanding question was, for some time - exactly which protein(s) can the spike actually turn into misfolded prion proteins? Is it tau? Perhaps TDP-43? PrPC?</p><p>Well, <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9551214/">it binds to all of them</a>.</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!NLOF!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Ff92e1841-d2b3-4a70-b20d-579afba79057_1000x1792.jpeg" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!NLOF!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Ff92e1841-d2b3-4a70-b20d-579afba79057_1000x1792.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!NLOF!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Ff92e1841-d2b3-4a70-b20d-579afba79057_1000x1792.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!NLOF!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Ff92e1841-d2b3-4a70-b20d-579afba79057_1000x1792.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!NLOF!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Ff92e1841-d2b3-4a70-b20d-579afba79057_1000x1792.jpeg 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!NLOF!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Ff92e1841-d2b3-4a70-b20d-579afba79057_1000x1792.jpeg" width="509" height="912.128" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/f92e1841-d2b3-4a70-b20d-579afba79057_1000x1792.jpeg&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:1792,&quot;width&quot;:1000,&quot;resizeWidth&quot;:509,&quot;bytes&quot;:391840,&quot;alt&quot;:null,&quot;title&quot;:null,&quot;type&quot;:&quot;image/jpeg&quot;,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:null,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="" srcset="/__u/substackcdn.com/image/fetch/$s_!NLOF!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Ff92e1841-d2b3-4a70-b20d-579afba79057_1000x1792.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!NLOF!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Ff92e1841-d2b3-4a70-b20d-579afba79057_1000x1792.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!NLOF!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Ff92e1841-d2b3-4a70-b20d-579afba79057_1000x1792.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!NLOF!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Ff92e1841-d2b3-4a70-b20d-579afba79057_1000x1792.jpeg 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption">Amyloidogenic spike binding resides. Click to expand. <em>Nystr&#246;m, S., &amp; Hammarstr&#246;m, P. (2022). Amyloidogenesis of SARS-COV-2 spike protein. Journal of the American Chemical Society, 144(20), 8945&#8211;8950. <a href="https://doi.org/10.1021/jacs.2c03925">https://doi.org/10.1021/jacs.2c03925</a></em></figcaption></figure></div><p>These residues on the spike bind to the many and varied amyloidogenic proteins, and those amyloid plaques begin to aggregate. Considering this action, in combination with the <a href="https://ashpublications.org/bloodadvances/article/6/7/2250/477738/SARS-CoV-2-spike-dependent-platelet-activation-in">spike-mediated activation of platelets</a>, <a href="https://pubmed.ncbi.nlm.nih.gov/33789211/">heparin amyloidogenesis</a>, and the trillions upon trillions of spikes delivered by one of those relatively rare, functional mRNA shots&#8230; </p><p></p><p>&#8230;and I think we just might have an answer as to where these come from:</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!Yk1n!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F9af74fe1-eece-4074-8b71-ae1fb9bf0a4c_653x563.jpeg" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!Yk1n!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F9af74fe1-eece-4074-8b71-ae1fb9bf0a4c_653x563.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!Yk1n!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F9af74fe1-eece-4074-8b71-ae1fb9bf0a4c_653x563.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!Yk1n!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F9af74fe1-eece-4074-8b71-ae1fb9bf0a4c_653x563.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!Yk1n!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F9af74fe1-eece-4074-8b71-ae1fb9bf0a4c_653x563.jpeg 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!Yk1n!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F9af74fe1-eece-4074-8b71-ae1fb9bf0a4c_653x563.jpeg" width="383" height="330.21286370597244" 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/__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F9af74fe1-eece-4074-8b71-ae1fb9bf0a4c_653x563.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!Yk1n!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F9af74fe1-eece-4074-8b71-ae1fb9bf0a4c_653x563.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!Yk1n!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F9af74fe1-eece-4074-8b71-ae1fb9bf0a4c_653x563.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!Yk1n!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F9af74fe1-eece-4074-8b71-ae1fb9bf0a4c_653x563.jpeg 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption"><a href="https://twitter.com/realstewpeters/status/1425652262018371584">Source</a> (sorry)</figcaption></figure></div><p>There is no further evidence, that I&#8217;m aware of, yet, that there is any subsequent growth or actual prion seeding taking place; those proteins bind to the spike, and that&#8217;s the end of it. The more spikes, the more binding, but it doesn&#8217;t appear to be actually modifying any of them to turn them into prion seeds. So, what we essentially have here is, instead of a silently cascading apocalypse, buried deep inside parts of the brain that we will never reach, we likely, instead, have these long, stringy, vein-shaped agglomerations of the various amyloid proteins, binding together wherever they meet, and apparently at least somewhat resistant to being broken down by the body&#8217;s natural processes for dealing with such eventualities.</p><p></p><p>So, that&#8217;s the first part of the good news: unless something&#8217;s been missed - which I would be able to tell, <em>if I had a lab</em>, but nevertheless - it seems like the zombie apocalypse should be off. If there is no secondary activation of different prion proteins, then all this is going to do is cause circulatory issues, blood clots, heart attacks, strokes and pulmonary embolisms among those unfortunate and/or short-sighted enough to have taken the COVID vaccines. Note that this also applies equally to the adenovirus vectors, the subunit protein vaccines like Novavax, and generally anything that&#8217;s deploying large numbers of spike proteins. The more, the worse - but, if it hasn&#8217;t killed you yet, or done irreversible damage to one&#8217;s heart via myocarditis, or caused IgG4 immune tolerance of SARS-CoV-2, or pervasive damage to the circulatory system, or &#8230;.</p><p>Fine, it&#8217;s still pretty grim for the vaxxies. Long, long ways to go until they won&#8217;t be perennially worrying about whether bringing in some heavy groceries will be their last act on this fair Earth. However, that is not the only good news.</p><p></p><h2>The Really Good News</h2><p>Now, we should all be clear that proteins are, chemically speaking, simply chains of molecules. For one protein to cause some action or effect on another, it generally must fit into a well-matching receptor site, whether it is a purpose-made receptor, or in the case of the spike proteins, a region that (perhaps) coincidentally just happens to fit. When something gets in the way, whether it&#8217;s a neutralizing antibody or a chemical of some description, the protein loses its ability, at that site, to bind to other proteins and cause whatever effect it is going to cause.</p><p>It has been known for quite some time that, amongst its many, many, <em>many</em> and varied other modes of action, <strong>ivermectin</strong> binds directly to the spike protein itself. Specifically, within the <a href="https://pubmed.ncbi.nlm.nih.gov/32871846/">receptor binding domain, at the L91 residue</a>. This interaction is useful for preventing the interaction between the spike protein and the ACE2 receptor, as the ivermectin molecule physically places itself in the way; if the spike is a key to the receptor&#8217;s lock, then ivermectin would be a big chunk of debris attached to the top, preventing the key from ever entering the keyhole.</p><p>Guess what else it is, thusly, useful for?</p><p>Preventing the amyloidogenic aggregations to the spike protein!</p><p>The spike is not like a typical prion, which is why the wording has been &#8220;Prion-Like Domain.&#8221; It is like a prion protein, insofar as it has the capability to bind to other proteins - specifically, itself - to form plaques, and this mechanism may also be of relevance to the long, stringy, proteinaceous blood clots that have been occasionally reported. Just as with this recent, and alarming <em>if true</em> reporting of SV40 DNA being identified in the shots - I would like to see some reproducibility, a second or third or fourth test from another source that can independently corroborate it. Once is happenstance, twice is coincidence, and three times is a pattern; to my knowledge, we&#8217;re sitting at <em>one</em> report right now. There have also been reports of graphene nanobots, alien squids, and various other contaminants, which needless to say have not been credibly corroborated. The shots alone are quite bad enough without inventing fanciful and quite obviously false BS.</p><p>With that said, it is also, however, unlike a prion protein, in that there is no misfolding or conformational change either caused, or necessary, to facilitate this binding action. Instead of an infection-like change upon contact, and a newly recognizable conformation of the spike, this interaction is much more akin to a couple of Velcro pads on either protein: the key fits the lock, and if they interact, they bind together. That simplifies the problem: just keep them from interacting, and you&#8217;re not going to have any formation of proteinaceous aggregates taking place. This should, in theory, apply equally to both the virus and the vaccine.</p><p></p><h3>Therapeutics</h3><p>Considering the fact that the vast majority of us have likely been repeatedly exposed to the virus over time - not to even get into the poor fools taking booster after booster - there is likely some degree of aggregation having already taken place. This work is closely related to the ALS work I was pursuing; these same protein aggregates, albeit through very different methods, are also observed and are likely at least partially responsible for the signs and symptoms of the various well-known neurodegenerative diseases. A number of relevant investigational therapeutics are noted in the very first article I published on Substack, <a href="/__u/veryvirology.substack.com/p/curing-the-incurable-als">here</a>; separately, an exploration of <a href="/__u/veryvirology.substack.com/p/serrapeptase-drano-for-your-vein">serrapeptase</a>, a proteolytic enzyme which may also be of some use. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696844/">Quercetin</a> has been noted to be of particular use insofar as disaggregation. Consider a rope, made of many thin strands of fiber; if you take a pair of scissors to it, it&#8217;s going to be pretty slow going, but if you first separate those strands, you&#8217;ll get a whole lot further, a whole lot faster. <a href="https://pubmed.ncbi.nlm.nih.gov/28790398/">Methylene blue</a> is another candidate, as is <a href="https://pubmed.ncbi.nlm.nih.gov/22465415/">resveratrol</a>, found in red wine, which has a <a href="https://pubmed.ncbi.nlm.nih.gov/30864708/">very</a> <a href="https://onlinelibrary.wiley.com/doi/10.1002/ptr.6732">broad</a> <a href="https://www.sciencedirect.com/science/article/pii/S2667137923000012">range</a> of <a href="https://gumc.georgetown.edu/news-release/resveratrol-appears-to-restore-blood-brain-barrier-integrity-in-alzheimers-disease/">useful</a> <a href="https://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-016-0779-0">actions</a>. I have to imagine that at least a large part of the reason there has been so little progress on these neurodegenerative diseases is your run-of-the-mill pharma and charity corruption; if they actually solved the problem, there wouldn&#8217;t be any reason for them to fundraise anymore.</p><p></p><h3>So, we have yet another application for ivermectin.</h3><p>I&#8217;ve said it before, and I&#8217;ll say it again: the more you look at ivermectin, the more you will find. Ivermectin is, without a shadow of a doubt at this point, a true miracle drug: with so many applications, from antiviral, to cancer treatment, to anti-inflammatory, and of course in its originally recognized anti-parasitic application, there should be little wonder why the powers that be have done their best to diminish it as &#8220;horse paste.&#8221; Whether it may be of any utility insofar as disaggregating already assembled plaques is a question I cannot answer, but it should (pending some experimental validation, which is probably never going to come) prevent such aggregation from initiating or continuing.</p><p></p><h4>Brain fog</h4><p>It&#8217;s also worth noting that, regarding the various degrees brain fog that many have experienced post-covid, a very unscientific poll I conducted on Twitter regarding brain fog found 80% reporting that a single, low dose of ivermectin - typically 150mcg/kg - had significantly improved their condition, in apparently short order. That may or may not be related to this functionality, or it may be yet another undiscovered application - but it&#8217;s definitely worth a footnote. Even with as much as we know now, there&#8217;s still a lot to learn. It is certainly conceivable that there may be some degree of disaggregatory effect.</p><p></p><h3>Wrapping up&#8230;</h3><p>I certainly did not plan to be writing just one single article over a month. </p><p>I still have a few pieces I&#8217;ve promised that will be forthcoming - aging, and vascular health in light of covid, are at the top of that list, as well as the eventual followup on East Palestine. (Regarding East Palestine, there is <a href="https://pubmed.ncbi.nlm.nih.gov/37189513/">now an article published to PubMed</a>, saying pretty much exactly what I had said, albeit a couple of months too late to actually help anybody get out in time.) Generally speaking, though, $7 really isn&#8217;t going as far as it did even six months ago, thanks largely to Brandon and our spineless Congress printing themselves up never-ending trillions of dollars - and between the general Twitter shadowbanning, and the Substack shadowbanning on top of that, I have been having to spend less time writing and more time elsewhere to just be able to get by. If you would like to see more frequent, more informative, and - well, let&#8217;s be honest, better - writing, consider becoming a paid subscriber. Until Substack and Twitter resolve their differences - if ever - they have made it very difficult to continue putting as much time into it as once I was. For those of you who are, it is greatly appreciated, as is your patience with the rather dramatically reduced volume lately, and I hope you can stick with us. Hopefully this will be just a temporary setback. <em>Also, the public metrics are apparently rather misleading: ~95% of y&#8217;all are free subscribers. We are not rich.</em></p><p>I&#8217;m also thinking about writing a criticism of Peter Hotez, his refusal to debate his conclusions and ostensibly sincerely held convictions, and the terrible impact this is going to have (and already has had) on the credibility and accuracy of the scientific method itself. We have, for some time, been told to just trust the science - which has, in practice, really meant trusting the scientists, like Fauci, like Andrew Hill, and like so many others whose conclusions are drawn not from an honest analysis of their work, but the imaginations and vested interests of whoever is lining their pockets. Moving forward from that era is starting to expose some of these people for what they really are; if we are to take their lead, then will we not simply be conducting science not by trial, error, and analysis, but by assertion and popular opinion? If I told you that everyone who took an mRNA vaccine was going to drop dead tomorrow, you might endorse that opinion, you might feel vindicated, and you might go tell others as much, and then they would do similarly. That might make me popular (until tomorrow, at least, unless I had a fawning media complex to clear it all up for me) - but would it be right?</p><p>Of course not. The lessons of Galileo are still as relevant today as ever. Science is supposed to be open; it is supposed to be questionable, falsifiable, and replicable; and now that this choice has been given to us, we should absolutely not stand for the kind of opaqueness that Hotez is telling us we should all just accept. If you have a position on something, and thousands or millions of people are taking your word for it and acting accordingly - <em>especially</em> if you have been telling them to take an experimental injection that has killed and maimed millions at this point - then you should be ready and willing to defend that position, and forsake it if you are proven wrong. I hold myself to that standard, and I expect nothing less of anyone else.</p><p>I have also been considering changing it up a little, and publishing short news updates on the health freedom movement, and the sprawling, many-faceted effort it has become over the years, in addition to these longer pieces. There&#8217;s been a lot of progress, on a lot of fronts, and more comes regularly as the world continues waking up. Let me know if you have any thoughts on that in the comments.</p><p>Thank you for reading, thank you for supporting us, and see you on Twitter!</p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://veryvirology.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">To receive new articles and support this work, please consider becoming a free or paid subscriber. It makes a difference!</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div>]]></content:encoded></item><item><title><![CDATA[Well, Apparently We're Not Going To Default]]></title><description><![CDATA[That's what I get for having any faith in any of these people.]]></description><link>https://veryvirology.substack.com/p/well-apparently-were-not-going-to</link><guid isPermaLink="false">https://veryvirology.substack.com/p/well-apparently-were-not-going-to</guid><dc:creator><![CDATA[Adam Gaertner]]></dc:creator><pubDate>Mon, 29 May 2023 04:13:00 GMT</pubDate><enclosure url="https://substack-post-media.s3.amazonaws.com/public/images/e41174cb-6c74-4ce0-b63b-fab39ac026be_1024x540.png" length="0" type="image/jpeg"/><content:encoded><![CDATA[<p>This will be a short one. I just got off a Space with Matt Gaetz, Lauren Boebert, and George Santos (can anybody explain why he was there?). They were parroting the same, tired old lines about how it&#8217;s really a much better deal than anyone expected, talking about Ukraine, the border wall, giving Santos speaking time (?!) and just generally stealing ten minutes of my time that I am never going to get back.</p><p></p><p>They gave absolutely no indication that they plan to use the powers they fought for - namely, a single Rep being able to initiate a vote of no confidence to vacate the Speaker&#8217;s chair - to do anything about this horrific disaster of a &#8220;deal.&#8221;</p><p></p><p>Lest I repeat myself, that&#8217;s what I get for having any faith in any of these people.</p><p></p><p>Congress is broken. If those guys aren&#8217;t going to stand up to this, I can&#8217;t imagine that any of them ever will. Swamp fever has the highest R0 of anything I&#8217;ve ever seen. I&#8217;m disgusted, I&#8217;m mad, and I was wrong.</p><p></p><p>It sure ain&#8217;t often that I&#8217;m accused of being an optimist.</p><p></p><p>Lesson learned.</p>]]></content:encoded></item><item><title><![CDATA[We're Going To Default (Actually, we're not.)]]></title><description><![CDATA[It's a political question, not an economic one (that I got wrong.)]]></description><link>https://veryvirology.substack.com/p/were-going-to-default</link><guid isPermaLink="false">https://veryvirology.substack.com/p/were-going-to-default</guid><dc:creator><![CDATA[Adam Gaertner]]></dc:creator><pubDate>Thu, 25 May 2023 04:09:22 GMT</pubDate><enclosure url="https://substack-post-media.s3.amazonaws.com/public/images/1396ea22-2ea4-4444-96ac-d8a67127db0a_945x608.png" length="0" type="image/jpeg"/><content:encoded><![CDATA[<p><em>Update: I was wrong. Gaetz is, apparently, just as bad as the rest of them, and has expressed no plan to do anything about it. I&#8217;ve taken the paywall down. Let this article stand as a shining example of the complete folly of having any faith in <strong>any</strong> of these politicians.</em></p><p></p><p><em>Lesson learned. Separate article coming shortly.</em></p><p></p><p>If you&#8217;ve been paying any attention - at all - to the political situation in which we find ourselves, you should probably have noticed by now that this is no ordinary situation. Every year we have this debate, every year they drag it out to the 11th hour, and every year they make a last-minute deal of some kind to avert the promised catastrophe.</p><p>This time is different.</p><p>Allow me, if you will, to tell you why.</p><p></p><p><em>Disclosure: Last Friday, I spent $40 (pretty much all I can spare) on OTM SPXU call options, strike $13.50, expiring 6/23. For those not financially inclined, that&#8217;s a very heavily leveraged position that will become profitable in the event of a severe drop in the S&amp;P 500, and end up worthless otherwise. As of today, those options are exactly ATM. I very rarely trade stocks etc, but an opportunity like this is just too good to pass up.</em></p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!QL5D!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F22265a41-b70f-4327-8b4c-6a1f5c2077a8_646x1248.jpeg" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!QL5D!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F22265a41-b70f-4327-8b4c-6a1f5c2077a8_646x1248.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!QL5D!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F22265a41-b70f-4327-8b4c-6a1f5c2077a8_646x1248.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!QL5D!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F22265a41-b70f-4327-8b4c-6a1f5c2077a8_646x1248.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!QL5D!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F22265a41-b70f-4327-8b4c-6a1f5c2077a8_646x1248.jpeg 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!QL5D!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F22265a41-b70f-4327-8b4c-6a1f5c2077a8_646x1248.jpeg" width="228" height="440.47058823529414" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/22265a41-b70f-4327-8b4c-6a1f5c2077a8_646x1248.jpeg&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:1248,&quot;width&quot;:646,&quot;resizeWidth&quot;:228,&quot;bytes&quot;:76498,&quot;alt&quot;:&quot;&quot;,&quot;title&quot;:&quot;&quot;,&quot;type&quot;:&quot;image/jpeg&quot;,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:null,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="" title="" srcset="/__u/substackcdn.com/image/fetch/$s_!QL5D!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F22265a41-b70f-4327-8b4c-6a1f5c2077a8_646x1248.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!QL5D!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F22265a41-b70f-4327-8b4c-6a1f5c2077a8_646x1248.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!QL5D!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F22265a41-b70f-4327-8b4c-6a1f5c2077a8_646x1248.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!QL5D!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F22265a41-b70f-4327-8b4c-6a1f5c2077a8_646x1248.jpeg 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption">Not financial advice; DYOR. But I&#8217;m putting my very limited money where my mouth is on this one.</figcaption></figure></div><p></p><h2>Game Theory</h2><p>I caught some flak for talking about game theory in relation to this. At its simplest, game theory deals with the incentives, motivations, and probabilities that motivate any given party to make the correct moves and maximize the chances for their optimal outcome. The Prisoner&#8217;s Dilemma is the Ur-example.</p><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!e85p!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F1ed3f2d9-dbc4-4e4d-985d-99ee9d53cc0a_1600x1600.jpeg" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!e85p!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F1ed3f2d9-dbc4-4e4d-985d-99ee9d53cc0a_1600x1600.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!e85p!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F1ed3f2d9-dbc4-4e4d-985d-99ee9d53cc0a_1600x1600.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!e85p!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F1ed3f2d9-dbc4-4e4d-985d-99ee9d53cc0a_1600x1600.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!e85p!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F1ed3f2d9-dbc4-4e4d-985d-99ee9d53cc0a_1600x1600.jpeg 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!e85p!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F1ed3f2d9-dbc4-4e4d-985d-99ee9d53cc0a_1600x1600.jpeg" width="416" height="416" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/1ed3f2d9-dbc4-4e4d-985d-99ee9d53cc0a_1600x1600.jpeg&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:1456,&quot;width&quot;:1456,&quot;resizeWidth&quot;:416,&quot;bytes&quot;:null,&quot;alt&quot;:&quot;Game theory - Prisoner's Dilemma, Theory of Moves, and Bourgeois Strategy |  Britannica&quot;,&quot;title&quot;:null,&quot;type&quot;:null,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:null,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="Game theory - Prisoner's Dilemma, Theory of Moves, and Bourgeois Strategy |  Britannica" title="Game theory - Prisoner's Dilemma, Theory of Moves, and Bourgeois Strategy |  Britannica" srcset="/__u/substackcdn.com/image/fetch/$s_!e85p!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F1ed3f2d9-dbc4-4e4d-985d-99ee9d53cc0a_1600x1600.jpeg 424w, /__u/substackcdn.com/image/fetch/$s_!e85p!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F1ed3f2d9-dbc4-4e4d-985d-99ee9d53cc0a_1600x1600.jpeg 848w, /__u/substackcdn.com/image/fetch/$s_!e85p!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F1ed3f2d9-dbc4-4e4d-985d-99ee9d53cc0a_1600x1600.jpeg 1272w, /__u/substackcdn.com/image/fetch/$s_!e85p!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F1ed3f2d9-dbc4-4e4d-985d-99ee9d53cc0a_1600x1600.jpeg 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption">Encyclopedia Britannica. <a href="https://www.britannica.com/science/game-theory/The-prisoners-dilemma">Source</a></figcaption></figure></div><p><br>There are, effectively, two parties to the dispute: President Biden&#8217;s handlers, and Speaker McCarthy. Both of them, as rational actors, want to secure the outcome that is the most beneficial to them personally. Does anybody expect any different from our politicians? That&#8217;s how the game is played, and this time is no different. What is different, this time, is the extremities of both their positions and their motivations. If there were going to be a deal, both Biden and McCarthy would need to win and lose a little. Give and take, compromise, the usual. So, what is motivating them, and what does it mean for the chances of a debt ceiling deal before a US default?</p><p></p><h3>Biden</h3><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!35Yw!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F4b383082-4a86-48ec-9b85-a3448eeb94ee_1024x1024.png" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!35Yw!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F4b383082-4a86-48ec-9b85-a3448eeb94ee_1024x1024.png 424w, /__u/substackcdn.com/image/fetch/$s_!35Yw!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F4b383082-4a86-48ec-9b85-a3448eeb94ee_1024x1024.png 848w, /__u/substackcdn.com/image/fetch/$s_!35Yw!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F4b383082-4a86-48ec-9b85-a3448eeb94ee_1024x1024.png 1272w, /__u/substackcdn.com/image/fetch/$s_!35Yw!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F4b383082-4a86-48ec-9b85-a3448eeb94ee_1024x1024.png 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!35Yw!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F4b383082-4a86-48ec-9b85-a3448eeb94ee_1024x1024.png" width="298" height="298" data-attrs="{&quot;src&quot;:&quot;https://substack-post-media.s3.amazonaws.com/public/images/4b383082-4a86-48ec-9b85-a3448eeb94ee_1024x1024.png&quot;,&quot;srcNoWatermark&quot;:null,&quot;fullscreen&quot;:null,&quot;imageSize&quot;:null,&quot;height&quot;:1024,&quot;width&quot;:1024,&quot;resizeWidth&quot;:298,&quot;bytes&quot;:1281365,&quot;alt&quot;:null,&quot;title&quot;:null,&quot;type&quot;:&quot;image/png&quot;,&quot;href&quot;:null,&quot;belowTheFold&quot;:true,&quot;topImage&quot;:false,&quot;internalRedirect&quot;:null,&quot;isProcessing&quot;:false,&quot;align&quot;:null,&quot;offset&quot;:false}" class="sizing-normal" alt="" srcset="/__u/substackcdn.com/image/fetch/$s_!35Yw!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F4b383082-4a86-48ec-9b85-a3448eeb94ee_1024x1024.png 424w, /__u/substackcdn.com/image/fetch/$s_!35Yw!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F4b383082-4a86-48ec-9b85-a3448eeb94ee_1024x1024.png 848w, /__u/substackcdn.com/image/fetch/$s_!35Yw!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F4b383082-4a86-48ec-9b85-a3448eeb94ee_1024x1024.png 1272w, /__u/substackcdn.com/image/fetch/$s_!35Yw!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F4b383082-4a86-48ec-9b85-a3448eeb94ee_1024x1024.png 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption">Ask not what China can do for you.</figcaption></figure></div><p>Let&#8217;s get the basics out of the way. Biden is a traitor. The Hunter laptop, among many other tidbits that have come out over time, have pretty clearly highlighted the fact that Biden is irrevocably beholden to several masters, China among them. If he were to defy their wishes, just like many of other corrupt politicians, we should expect to see graphic child abuse imagery involving at least him and Hunter, among God only knows what else they, or other parties, are holding over him. China already <a href="https://www.washingtontimes.com/news/2023/apr/12/china-sent-not-so-subtle-threat-joe-biden-revealin/">disclosed</a> Hunter&#8217;s financial records to Senate Republicans, leaving not a shred of doubt that they are quite willing and able to pull that chain if he were to stray too far from his orders.</p><p>So, for starters, we have a President that is firmly beholden to our enemies. What would China, or anybody else who has power over him, like to see for their money?</p><p>Well, presuming that they <em>are</em> acting in their national interest, they&#8217;d probably like to see the US suffer, in some way or another. BRICS is in the middle of a worldwide campaign to de-dollarize the global economy; a US debt default would, among the multitude of other terrible economic effects, crush the value of US Treasuries, severely damage the credibility and reputation of the US dollar, and likely give a big boost to their competing plans. Of course, it&#8217;s going to get stronger before it gets weaker - as the world&#8217;s reserve currency, the Dollar Milkshake theory is in full effect, and so as people, institutions and countries divest themselves of increasingly risky USD-denominated assets, what will they trade them for? Dollars, of course. That will paradoxically drive up the value of the USD in the midst of that economic chaos: at least, until everybody decides to trade their dollars for whatever hard assets they can still get for them.</p><p>But surely he still has to worry about re-election, right? Also, not really - if you don&#8217;t understand by now that the 2020 (and 2022) elections were severely rigged, then there&#8217;s probably no helping you. Biden said it himself: <a href="https://twitter.com/TrumpWarRoom/status/1322677836713545729">he doesn&#8217;t need you to get elected</a>. Any ordinary POTUS would be rightly very concerned that a gigantic, messy, chaotic economic crisis on their watch might harm their re-election chances. No such luck with this guy.</p><p>It&#8217;s also worth noting at this point that McCarthy himself recently said as much: &#8220;<a href="https://www.zerohedge.com/political/debt-ceiling-negotiations-crumble-mccarthy-and-biden-hold-sunday-call-impasse-intensifies">It seems like Biden </a><em><a href="https://www.zerohedge.com/political/debt-ceiling-negotiations-crumble-mccarthy-and-biden-hold-sunday-call-impasse-intensifies">wants</a></em><a href="https://www.zerohedge.com/political/debt-ceiling-negotiations-crumble-mccarthy-and-biden-hold-sunday-call-impasse-intensifies"> to default.</a>&#8221; Why would Biden possibly want that? Of course the Democrats are trying to lay the blame on Republicans; if they can get away with that, all the better, and maybe that&#8217;ll give them some cover to explain away another blatantly stolen election. That said, that&#8217;s a rather extreme, and telling, statement. It is a basic, undeniable fact that the US government brings in far more revenue than is required to keep up on debt service; the ongoing revenues are sufficient to cover those payments, including bond maturities (paying back the principal amount of a Treasury bill when it comes due, not just the interest). A debt default will not happen automatically; depending on how the Treasury balances change day to day, it&#8217;s likely that Biden would need to explicitly order the Treasury to default on those bond payments to prioritize something else.</p><p>In other words: The only realistic scenario of a US debt service default is the situation in which Biden actually wants one.</p><p>There&#8217;s also the incipient CBDCs, or Central Bank Digital Currencies. The Federal Reserve has been developing the FedNow &#8220;service&#8221; to that end. It was originally <a href="https://www.federalreserve.gov/newsevents/pressreleases/other20230315a.htm">scheduled for release</a> on July 1st; that may have been <a href="https://westfaironline.com/banking-finance/fednow-speeds-up-money-transfers/">moved up to June 1st</a>. Seeing as the expected default date is June 1st - why, I wonder, would they possibly do that? Biden is, of course, full steam ahead on board with the Great Reset, better known to some as the &#8220;Build Back Better&#8221; plan. It was literally his campaign&#8217;s tagline! CBDCs, which are programmable digital currencies, are a critical element of the &#8220;Fourth Industrial Revolution&#8221; under which we are all supposed to be digitally enslaved. They give the issuer the ability to view every transaction you&#8217;ve ever made, arbitrarily restrict where, when, with whom, or how much you are allowed to spend, grant them the ability to implement negative interest rates or time-limited allowances - that is to say, if you have $600 right now, you&#8217;d better spend it, because it will expire at the end of the month - as well as limiting the amount of savings you are allowed to build up. The FedNow service, intended for use between large financial institutions, is their first operational toe in the water. T-bills are <a href="https://www.kroll.com/en/insights/publications/the-federal-reserve-rides-to-the-rescue">primarily</a> behind the banking crisis: the banks held them as collateral, and with skyrocketing interest rates, they lost a lot of their value, decimating the banks&#8217; capital and collateral they are legally and contractually required to maintain.</p><p>The official reserve ratio is currently 0% - at the bottom line, they are allowed to maintain zero reserves to cover customers&#8217; assets, withdrawals, et cetera - but once their liabilities exceed the value of their assets, that situation is known as bankruptcy, and they end up being seized by regulators. T-bills, once thought to be among the safest assets in existence, have already taken a heavy hit to their value, and a sovereign debt default ain&#8217;t gonna help matters. The Federal Reserve has implemented the <a href="https://www.federalreserve.gov/newsevents/pressreleases/monetary20230312a.htm">BTFP</a> program, directly buying T-bills from the banks above their newly decimated market value; a whole lot more of them are going to need that help if they have any chance of surviving a US sovereign debt default. What better, more convenient way to implement that program than the new CBDC? It could also, if the federal government stops funding Social Security, food stamps, et cetera, allow the Fed to unilaterally magic the money into existence even more efficiently. Of course, it would take one hell of a crisis for anybody to accept that.</p><p>We now have a few reasons each why Biden both will not be negatively affected by causing a sovereign debt default, and why he and his puppet masters will actually benefit from the chaos, destruction, poverty and suffering it will cause across the board. So, with that said &#8230;</p><p><strong>There is not a snowball&#8217;s chance in Hell that Biden won&#8217;t allow, or cause, the default.</strong></p><p></p><h3>McCarthy</h3><div class="captioned-image-container"><figure><a class="image-link image2 is-viewable-img" target="_blank" href="/__u/substackcdn.com/image/fetch/$s_!5M65!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fdad8d2bf-0e9b-4cc6-90b2-0fb0c2be22a3_1024x1024.png" data-component-name="Image2ToDOM"><div class="image2-inset"><picture><source type="image/webp" srcset="/__u/substackcdn.com/image/fetch/$s_!5M65!, /__u/veryvirology.substack.com/w_424, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fdad8d2bf-0e9b-4cc6-90b2-0fb0c2be22a3_1024x1024.png 424w, /__u/substackcdn.com/image/fetch/$s_!5M65!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fdad8d2bf-0e9b-4cc6-90b2-0fb0c2be22a3_1024x1024.png 848w, /__u/substackcdn.com/image/fetch/$s_!5M65!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fdad8d2bf-0e9b-4cc6-90b2-0fb0c2be22a3_1024x1024.png 1272w, /__u/substackcdn.com/image/fetch/$s_!5M65!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_webp, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fdad8d2bf-0e9b-4cc6-90b2-0fb0c2be22a3_1024x1024.png 1456w" sizes="100vw"><img src="/__u/substackcdn.com/image/fetch/$s_!5M65!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fdad8d2bf-0e9b-4cc6-90b2-0fb0c2be22a3_1024x1024.png" width="296" height="296" 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/__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fdad8d2bf-0e9b-4cc6-90b2-0fb0c2be22a3_1024x1024.png 424w, /__u/substackcdn.com/image/fetch/$s_!5M65!, /__u/veryvirology.substack.com/w_848, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fdad8d2bf-0e9b-4cc6-90b2-0fb0c2be22a3_1024x1024.png 848w, /__u/substackcdn.com/image/fetch/$s_!5M65!, /__u/veryvirology.substack.com/w_1272, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fdad8d2bf-0e9b-4cc6-90b2-0fb0c2be22a3_1024x1024.png 1272w, /__u/substackcdn.com/image/fetch/$s_!5M65!, /__u/veryvirology.substack.com/w_1456, /__u/veryvirology.substack.com/c_limit, /__u/veryvirology.substack.com/f_auto, /__u/veryvirology.substack.com/q_auto:good, /__u/veryvirology.substack.com/fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2Fdad8d2bf-0e9b-4cc6-90b2-0fb0c2be22a3_1024x1024.png 1456w" sizes="100vw" loading="lazy"></picture><div class="image-link-expand"><div class="pencraft pc-display-flex pc-gap-8 pc-reset"><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container restack-image"><svg aria-hidden="true" width="20" height="20" viewBox="0 0 20 20" fill="none" stroke-width="1.5" stroke="var(--color-fg-primary)" stroke-linecap="round" stroke-linejoin="round" xmlns="http://www.w3.org/2000/svg"><g><path d="M2.53001 7.81595C3.49179 4.73911 6.43281 2.5 9.91173 2.5C13.1684 2.5 15.9537 4.46214 17.0852 7.23684L17.6179 8.67647M17.6179 8.67647L18.5002 4.26471M17.6179 8.67647L13.6473 6.91176M17.4995 12.1841C16.5378 15.2609 13.5967 17.5 10.1178 17.5C6.86118 17.5 4.07589 15.5379 2.94432 12.7632L2.41165 11.3235M2.41165 11.3235L1.5293 15.7353M2.41165 11.3235L6.38224 13.0882"></path></g></svg></button><button tabindex="0" type="button" class="pencraft pc-reset pencraft icon-container view-image"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-maximize2 lucide-maximize-2"><polyline points="15 3 21 3 21 9"></polyline><polyline points="9 21 3 21 3 15"></polyline><line x1="21" x2="14" y1="3" y2="10"></line><line x1="3" x2="10" y1="21" y2="14"></line></svg></button></div></div></div></a><figcaption class="image-caption">If you give the House to the Freedom Caucus, you&#8217;re gonna have a bad time.</figcaption></figure></div><p>Well, fortunately for the rest of us, Biden isn&#8217;t the only party to this debate. McCarthy is a well-known RINO; the man is slimy, opportunistic, self-interested, made-man Uniparty personified. Everybody expects the Republicans to fold - we&#8217;re all well and truly used to the pithy spinelessness that has defined the Republican Party for the last few decades. They talk a big game, they take it to the wire, and then they disappoint us all and fold like the cheap, empty suits they are. Why is this time any different?</p><p>Well, for starters, McCarthy is not in charge. You may have heard that it took him 15 votes to successfully take the Speaker&#8217;s gavel, and that he made some concessions to be able to do so. Among those concessions, we have these three shining gems.</p><ol><li><p><strong>The Freedom Caucus controls the Rules Committee.</strong> The Rules Committee decides, in this Congress, and among numerous other duties, which bills are allowed to come to the floor for a vote. Pelosi ruled the House with an iron, autocratic fist: she alone kept the power to decide what would come up for a vote. That is not the situation in this Congress.</p></li><li><p><strong>The three-day rule.</strong> The three-day rule means that any bill, no matter how urgent, must be debated for a minimum of three days before coming up for a vote. This dramatically shortens the true deadline. As I write this, we have 8 days until the money runs out and the US defaults on something. If the Democrats want to negotiate another bill - they don&#8217;t, but let&#8217;s play pretend - McCarthy has plainly stated that this rule will still apply. If they were to somehow convince the House to vote on, and pass, a &#8220;clean&#8221; debt ceiling bill, then they must do so within the next <em>five</em> days. This will also give us three days&#8217; notice that we do, in fact, stand at the cliff-edge: once that deadline has elapsed, the House couldn&#8217;t pass a &#8220;clean&#8221; debt ceiling bill in time if they wanted to. Separating the deadlines is going to make for some interesting partisan brinksmanship, as the only answer at that point will then be either signing the already-passed House bill that contains major cuts, or some doomed gimmick like the 14th Amendment or the trillion-dollar coin.</p></li><li><p><strong>The vote of no-confidence.</strong> This is the true Sword of Damocles hovering over McCarthy&#8217;s head, and this is what truly grants the Freedom Caucus full control of the House and everything that happens, or doesn&#8217;t happen, therein. If McCarthy were to bend to the Democrats&#8217; demands - or the RINO demands - a single Representative, most likely Matt Gaetz, may force a vote of no confidence. If that happens, Speaker McCarthy is no longer, and all House business promptly ceases until such time as a new Speaker is elected. That could go on for quite a while, depending on just how hard the Republicans dig in their heels, but one thing is certain: there won&#8217;t be <em>any</em> new bills passing the House until that&#8217;s resolved, and certainly not a clean debt ceiling bill.</p></li></ol><p></p><p>So, we&#8217;re putting a lot of faith in the likes of Matt Gaetz and Jim Jordan here. What makes them so special? Why are we presuming that they&#8217;re going to take this game of chicken to the messy conclusion when neither party budges?</p><p>Well, for starters, you could ask McConnell. In last year&#8217;s session, the lame-duck Congress, with the Senate led by McConnell and the House by Pelosi, passed a $1.7 trillion budget for the next year. That is a rather unusual action. Congress&#8217; primary means of oversight and control is the &#8220;power of the purse;&#8221; that is, the power to spend, borrow, or prohibit same. By passing that budget in the lame-duck session, using undemocratic tricks to ram it through an otherwise skeptical Congress, McConnell, RINO extraordinaire that he is, worked with the Democrats to kneecap the incoming Congress. Why would he take such an extreme measure? Why would he deny the new House any power of negotiation, any reason for the White House to talk to them or take them seriously, for so long?</p><p>Why indeed.</p><p>Furthermore, these Republicans are the very same that have formed and are heading up the Select Subcommittee on the Weaponization of the Federal Government, better known as just Weaponization. They&#8217;re going after the corrupt FBI, DOJ, CIA, IRS, so on, and so forth - tomorrow, Durham will be facing some very difficult questions regarding both the extensive criminal conspiracy to frame Trump, and why, exactly, he has apparently decided not to lay any criminal charges for those actions. This is not entirely unprecedented, but I can&#8217;t imagine the Swamp appreciates their many and varied crimes being aired out for all to see. These guys are fully informed of the depth of corruption, criminality and treason of the Biden Administration, and they know the stakes of allowing this supremely corrupt administration to continue wielding the awesome power of the federal government. Continuing to fund it is not exactly high on their list of priorities.</p><p>Beyond that, I don&#8217;t really know what else to tell you - if you think Matt Gaetz is going to fold on this, then you go right ahead and believe that, and we&#8217;ll see who stands where come June. For all the clownery around &#8220;patriots are in control,&#8221; for once in our lives, that statement is true. At least insofar as control of the House.</p><p>A US government default is going to be an extraordinarily disruptive event, socially, economically, and politically, and we have a traitor for a POTUS that is almost assuredly going to go out of his way to make it as painful as absolutely possible. If you are reliant on government money, programs or support, in any way, I would strongly suggest that you should do what you can to prepare for that to go away, for at least a little while.</p><p>In the worst case, we could emerge into a whole new world.</p><p></p><p>Thank you for reading, and I hope you learned something - this time is definitely not like all the other times. As we get closer to the deadline over the next few days, I expect it will become rather quite clearer than it is right now - I&#8217;ll be tracking the developments on Twitter. I do have another couple of articles in the works, regarding both vascular health, in light of the extensive damage caused by the spike protein, and compensating for lacking immune function, of varying severities, due to the same; you might be surprised to learn that research takes time, and I can&#8217;t really just rush out a new article every few days. (I could, but I can&#8217;t imagine they would really be worth reading.) We&#8217;re also a month or two away from my next update on East Palestine, and the fallout in surrounding areas, which I know a few of you have been waiting for; I am waiting for the effects to begin appearing before I revisit that again. With the continuing craziness of events this month, I have been very busy. Your continued support is greatly appreciated, and it makes all the difference to us.</p><p>Stay tuned, and see you on Twitter!</p><p></p><p></p>]]></content:encoded></item><item><title><![CDATA[Curing Cancer: Success!]]></title><description><![CDATA[Two months later, one man is completely cancer-free.]]></description><link>https://veryvirology.substack.com/p/curing-cancer-success</link><guid isPermaLink="false">https://veryvirology.substack.com/p/curing-cancer-success</guid><dc:creator><![CDATA[Adam Gaertner]]></dc:creator><pubDate>Tue, 02 May 2023 06:34:31 GMT</pubDate><enclosure url="https://substack-post-media.s3.amazonaws.com/public/images/20e41792-6aee-4431-9415-73964a1f47d2_968x643.png" length="0" type="image/jpeg"/><content:encoded><![CDATA[<p>When I determined that ivermectin was curative for COVID, all the way back in April of 2020, I did so based on what was, at the time, relatively thin evidence. I had a pile of mechanistic research, a report from a hospital in South America that had begun to use it because they&#8217;d run out of hydroxychloroquine, a novel theory concerning the immunology at play, and a protocol, developed at length, with consideration of numerous microbiological and virological factors that ordinarily wouldn&#8217;t warrant so much as a second glance in that context.</p><p>Similarly, I find myself now in almost precisely the same position as regards this cancer protocol. I have a novel theory of immunology, a pile of mechanistic research, a protocol, and now, <em>very</em> limited, but nonetheless extant, evidence of use and success <em>in vivo</em>.</p><p></p><p><em>You can read the original article, detailing the mechanisms and the protocol, <a href="/__u/veryvirology.substack.com/p/curing-the-incurable-cancer">here</a>.</em></p><p></p><p>Without further ado:</p><p></p><h3>Case Report - Patient 1</h3><p><em>The patient, a 60 year old male with a history of nodular basal cell carcinoma on the chest and melanoma on the ring finger, started the protocol approximately 4 weeks prior to reporting. The patient's diet was also modified to be mostly organic, low carb, and vegetable-centric, while monitoring systemic acid/base balance using urine pH strips. The patient also applied a 10% ivermectin and fenbendazole topical cream on the affected areas.</em></p><p><em>Progress:</em></p><ul><li><p><em>Days 1-10: No notable changes.</em></p></li><li><p><em>Day 11: Inflammation and severe itching observed on the back of the hand and a 1x3 inch area above the basal cell. Oozing of clear amber liquid noted.</em></p></li><li><p><em>Day 15: The pink spot on the ring finger darkened, transformed into a bump, and the whole area became swollen and red.</em></p></li><li><p><em>Day 30+: The skin on the red oozing areas began sloughing off and was replaced by tender pink "baby skin." The chest basal cell shrank only slightly, and the hands and chest began healing.</em></p></li></ul><p><em>Additional Treatments: The patient applied c-herb to the ring finger, resulting in a tiny hole where the dark spot/bump used to be. The chest basal cell was also treated next with c-herb. Timing of these additions is unclear.</em></p><p><em>Outcome: Both the chest lesion and the ring finger lesion disappeared, leaving craters in their places - the tumor on the chest wholly detached and fell off. The patient treated the craters with sangre de grado, and both areas have healed well: the skin on the back of the hand and chest area is now fully healed, with a healthy, normal appearance.</em></p><p></p><h3>Takeaways</h3><p>I am very surprised that two months later, despite a few people having indicated that they intended to begin using the protocol, I have only heard results from two people. The second report, which may have been confounded, and does not appear to have been as successful - but may contain useful lessons, nonetheless - follows further down the article, but let&#8217;s talk about this case first.</p><p>The man had a history of melanoma on the ring finger, which was thought to have been successfully excised quite some time ago. However, upon the 11th day of the protocol - the day at which the immune reaction is prompted by therapeutics to begin in earnest, after the first 10 days of preparation - and much to his surprise, the localized cytokine storms began not only near the chest tumor, but also on the hand. This indicates three things to me:</p><ol><li><p><strong>The preparation phase was successful.</strong></p><p>The protocol starts out with high dose IVM and FBZ, followed by alternating days of ascorbic acid and sodium bicarbonate treatment, with lower dose FBZ. This phase is intended to cause metabolic stress to the tumor&#8217;s microenvironment, modifying the cytokine profile, destroying just a few cells, and giving the immune system a sample of the antigenic profile of the solid tumor mass, with which B and T cells can learn and develop the appropriate recognition and responses. This process is ordinarily inhibited by the inaccessibility of the tumor, due to the numerous and varied immune suppression functions they exhibit.</p><p></p></li><li><p><strong>The &#8220;nuke it from orbit&#8221; strategy was successful.</strong></p><p>And how! By giving the immune system sufficient time to learn to recognize the tumor antigens, and subsequently hitting the tumor with higher doses IVM and FBZ again, whilst ceasing the anti-inflammatory ascorbic acid that was used to soften it up via the Warburg effect, the therapeutic profile of the 11th day creates a perfect storm - a cytokine storm, at that - of immune response at the site of the tumor. This was precisely what I had theorized should happen; I couldn&#8217;t have imagined a more successful result in my dreams.</p><p></p></li><li><p><strong>The protocol is not harmless - you must seek medical advice and supervision.</strong></p></li></ol>
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